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Performance of planar multisite microprobes in recording extracellular single-unit intracortical activity
Abstract
The microprobes consist of a thin-film electrode array supported by a silicon micromachined substrate and insulated using deposited dielectrics. Microprobes with multiple recording sites spaced from 30 mu m to 200 mu m apart are used to record spontaneous single-unit activity from rat cerebral cortex. Additionally, a theoretical model is used to establish a basis for interpreting the multisite single-unit data. The results suggest that the microprobes (1) couple tightly to the neural tissue with relatively little disturbance to the neural system, (2) facilitate the identification of single units in multiunit records through the use of spatially-separate recording sites, and (3) can be used to detect the cell position in tissue and observe events such as the propagation of electrical activity from the soma to the dendritic tree.>
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Cites
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Wise, K. D., Angell, J. B., & Starr, A. (1970) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1970.4502738 · Cited by 544
Self-citation
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Cited by
Response of brain tissue to chronically implanted neural electrodes
Polikov, V. S., Tresco, P. A., & Reichert, W. M. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2005.08.015 · Cited by 1,896
Intracellular Features Predicted by Extracellular Recordings in the Hippocampus In Vivo
Henze, D. A., Borhegyi, Z., Csicsvari, J., Mamiya, A., Harris, K. D., & Buzsáki, G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.1.390 · Cited by 942
Biran, R., Martin, D. C., & Tresco, P. A. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.04.020 · Cited by 893
Navarro, X., Krueger, T. B., Lago, N., Micera, S., Stieglitz, T., & Dario, P. (2005) · Journal of the Peripheral Nervous System · doi:10.1111/j.1085-9489.2005.10303.x · Cited by 845
Flexible and Stretchable Electronics for Biointegrated Devices
Kim, D.-H., Ghaffari, R., Lu, N., & Rogers, J. A. (2012) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071811-150018 · Cited by 749
Metadata
- Authors
- Drake, K. L., Wise, K. D., Farraye, J., Anderson, D. J., & BeMent, S. L.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 1988
- Volume
- 35
- Issue
- 9
- Pages
- 719-732
- ISSN
- 0018-9294 (ISSN-L)
- OpenAlex
- W2030275688
- Cited by
- 362
- References
- 1
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Drake, K. L., Wise, K. D., Farraye, J., Anderson, D. J., & BeMent, S. L. (1988). Performance of planar multisite microprobes in recording extracellular single-unit intracortical activity. IEEE Transactions on Biomedical Engineering. https://doi.org/10.1109/10.7273
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