A cable-tie-type parylene cuff electrode for peripheral nerve interfaces
Abstract
We have designed, fabricated and characterized a cable-tie-type parylene cuff electrode for peripheral nerve interfaces, whose diameter is adjustable to accommodate the nerve properly during implantation. Cuffs made of thin and flexible parylene minimize mechanical damage to surrounding tissues after implantation. Moreover, the integrated parylene cable and pads facilitate the connection with external circuits through wired or wireless interfaces. Using the fabricated cable-tie-type parylene cuff electrodes, acute neural recoding and stimulation tests were performed on the rat sciatic nerve to verify the capabilities of recording the neural activity and selectively stimulating different nerve fascicles.
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Previous studies of peripheral implants used for rodents have reported peak-to-peak signal amplitudes ranging from 100-900 μV in response to electrical stimuli.
“Previous studies of peripheral implants used for rodents have reported peak-to-peak signal amplitudes ranging from 100–900 μV in response to electrical stimuli [22–27].”
From A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve (2017) · cites this paper as [24]
Cites
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Sullivan, R. P. (2018) · Research Online (University of Wollongong)
- Authors
- Yu, H., Xiong, W., Zhang, H., Wang, W., & Li, Z.
- Affiliations
- Peking University (CN)
- Venue
- 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)
- Publisher
- IEEE
- Published
- 2014-01
- Pages
- 9-12
- ISSN
- 1084-6999 (ISSN-L)
- OpenAlex
- W2054966062
- Cited by
- 10
- References
- 10
- Citations by year
- 2024: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 1
- FWCI
- 4.77
- Type
- conference paper
- Language
- en
- Open access
- closed
- Locations
- IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (publishedVersion)
- Funders
- Centre National de la Recherche Scientifique
- Peking University
- National Key Laboratory of Science and Technology on Micro/Nano Fabrication
- National Key Research and Development Program of China
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Undergraduate Neuroscience Education and Research
- Keywords
- parylene, cuff electrodes, peripheral nerve interfaces, neural recording, neurostimulation, sciatic nerve, rats, wireless interface
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