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Chia Seed ( Salvia hispanica L.) as a Source of Proteins and Bioactive Peptides with Health Benefits: A Review
Abstract
The consumption of chia seed (Salvia hispanica L.) has increased in recent years due its high content of omega-3 fatty acids and dietary fiber. This seed also has a high concentration of proteins and essential amino acids, becoming a promising source of bioactive peptides. The objective of this review was to identify the composition and the beneficial effects of chia seeds (S. hispanica L.), their proteins, peptides, and their potential impact on human health. The UniProt database was used to identify the chia proteins and their amino acid sequences. The BIOPEP database was used to analyze the peptides's bioactive potential. A total of 20 proteins were cataloged in chia seed, 12 of those were involved in the regular metabolic processes of the plant cells. However, eight proteins were specifically related to production and storage of plant lipids, thus explaining the high concentration of lipids in chia seeds (around 30%), especially omega-3 fatty acids (around 20%). The analyses of amino acid sequences showed peptides with bioactive potential, including dipeptidyl peptidase-IV inhibitors, angiotensin-converting enzyme inhibitors, and antioxidant capacity. These results correlated with the main health benefits of whole chia seed in humans such as antioxidant capacity, and hypotensive, hypoglycemic, and anticholesterolemic effects. Such relation can be associated with chia protein and peptide compositions and therefore needs further investigation in vitro and in vivo.
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“Also, rosmarinic acid, found in higher amounts, acts as the most abundant antioxidant present in chia seeds, i.e., 0.93 mg/g, followed by three other phenolic compounds, i.e., protocatechuic acid, caffeic acid, and gallic acid with concentrations of 0. 75, 0.03, and 0.01 mg/g, respectively [87,88,94].”
From Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds (2023) · cites this paper as [88]
In the citing paper
“Digested proteins of chia seeds exhibit anti-inflammatory and anti-adipogenic effects [88].”
From Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds (2023) · cites this paper as [88]
Citations
Cites
UniProt: the Universal Protein knowledgebase
Apweiler, R. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkh131 · Cited by 7,593
UniProt: the universal protein knowledgebase
The UniProt Consortium (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw1099 · Cited by 4,436
Protein and amino acid requirements in human nutrition.
(2007) · PubMed · Cited by 2,234
Molecular targets of dietary agents for prevention and therapy of cancer
Aggarwal, B. B., & Shishodia, S. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.02.009 · Cited by 1,774
Tripathi, D. K., Mishra, R. K., Singh, S., Singh, S., Vishwakarma, K., Sharma, S., Singh, V. P., Singh, P. K., Prasad, S. M., Dubey, N. K., et al. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.00001 · Cited by 1,177
Food Protein‐Derived Bioactive Peptides: Production, Processing, and Potential Health Benefits
Udenigwe, C. C., & Aluko, R. E. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2011.02455.x · Cited by 1,069
Regulation of inflammation and redox signaling by dietary polyphenols
Rahman, I., Biswas, S. K., & Kirkham, P. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.07.004 · Cited by 1,003
Structure and function of Rubisco
Andersson, I., & Backlund, A. (2008) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2008.01.001 · Cited by 580
Physiological and developmental regulation of seed oil production
Baud, S., & Lepiniec, L. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.01.001 · Cited by 527
Yousef-Yousef, M., Alba-Ramírez, C., Garrido‐Jurado, I., Mateu, J., Raya–Díaz, S., Valverde‐Garcia, P., & Quesada‐Moraga, E. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00001 · Cited by 521
Reyes-Caudillo, E., Tecante, A., & Valdivia-López, M. A. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2007.08.062 · Cited by 462
Jackson, L. P., Kelly, B. T., McCoy, A. J., Gaffry, T., James, L. C., Collins, B. M., Höning, S., Evans, P. R., & Owen, D. J. (2010) · Cell · doi:10.1016/j.cell.2010.05.006 · Cited by 389
Chia seeds: Microstructure, mucilage extraction and hydration
Muñoz, L. A., Cobos, Á., Rubio, O. D., & Aguilera, J. M. (2011) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2011.06.037 · Cited by 376
Nutritional and therapeutic perspectives of Chia (Salvia hispanica L.): a review
Ullah, R., Nadeem, M., Khalique, A., Imran, M., Mehmood, S., Javid, A., & Hussain, J. (2016) · Journal of Food Science and Technology · doi:10.1007/s13197-015-1967-0 · Cited by 365
Cicero, A. F. G., Fogacci, F., & Colletti, A. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13608 · Cited by 355
Capitani, M. I., Spotorno, V., Nolasco, S. M., & Tomás, M. C. (2012) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2011.07.012 · Cited by 325
Physical properties of chia (Salvia hispanica L.) seeds
Ixtaina, V. Y., Nolasco, S. M., & Tomás, M. C. (2008) · Industrial Crops and Products · doi:10.1016/j.indcrop.2008.03.009 · Cited by 320
The FAD2 Gene in Plants: Occurrence, Regulation, and Role
Dar, A. A., Choudhury, A. R., Kancharla, P. K., & Arumugam, N. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01789 · Cited by 314
Hu, Y., Li, J., Liu, P., Chen, X., Guo, D., Li, Q., & Rahman, K. (2011) · BioMed Research International · doi:10.1155/2012/728342 · Cited by 311
Ayerza, R., & Coates, W. E. (2011) · Industrial Crops and Products · doi:10.1016/j.indcrop.2010.12.007 · Cited by 296
Plant Lipid Droplets and Their Associated Proteins: Potential for Rapid Advances
Huang, A. H. C. (2017) · PLANT PHYSIOLOGY · doi:10.1104/pp.17.01677 · Cited by 287
The Promising Future of Chia,Salvia hispanicaL.
Ali, N. M., Yeap, S. K., Ho, W. Y., Beh, B. K., Tan, S. W., & Tan, S. G. (2012) · BioMed Research International · doi:10.1155/2012/171956 · Cited by 270
Isolation and Characterization of Proteins from Chia Seeds (Salvia hispanica L.)
Sandoval-Oliveros, M. R., & Paredes‐López, O. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3034978 · Cited by 267
Physicochemical and functional properties of protein isolate produced from Australian chia seeds
Timilsena, Y. P., Adhikari, R., Barrow, C. J., & Adhikari, B. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.06.017 · Cited by 258
Martínez‐Cruz, O., & Paredes‐López, O. (2014) · Journal of Chromatography A · doi:10.1016/j.chroma.2014.04.007 · Cited by 217
Vuksan, V. V. V., Whitham, D., Sievenpiper, J. L., Jenkins, A. L., Rogovik, A. L., Bazinet, R. P., Vidgen, E., & Hanna, A. (2007) · Diabetes Care · doi:10.2337/dc07-1144 · Cited by 197
Chemical and Functional Properties of Chia Seed (Salvia hispanicaL.) Gum
Campos, M. R. S., Ciau-Solís, N., Rosado-Rubio, G., Chel‐Guerrero, L., & Betancur‐Ancona, D. (2014) · International Journal of Food Science · doi:10.1155/2014/241053 · Cited by 193
Poudyal, H., Panchal, S. K., Waanders, J., Ward, L. C., & Brown, L. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.11.011 · Cited by 192
Characterization of phenolic compounds in chia (Salvia hispanica L.) seeds, fiber flour and oil
Oliveira-Alves, S. C., Vendramini-Costa, D. B., Betim Cazarin, C. B., Maróstica Júnior, M. R., Borges Ferreira, J. P., Silva, A. B., Prado, M. A., & Bronze, M. R. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.04.002 · Cited by 192
Amaranth, quinoa and chia protein isolates: Physicochemical and structural properties
López, D. N., Galante, M., Robson, M., Boeris, V., & Spelzini, D. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.12.080 · Cited by 190
Chemical composition of Brazilian chia seeds grown in different places
da Silva, B. P., Anunciação, P. C., Matyelka, J. C. D. S., Lúcia, C. M. D., Martino, H. S. D., & Pinheiro-Sant’Ana, H. M. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.10.115 · Cited by 188
Meisel, H. (1997) · Livestock Production Science · doi:10.1016/s0301-6226(97)00083-3 · Cited by 186
Kato, Y., & Sakamoto, W. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00855 · Cited by 183
Antioxidant capacity and chemical composition in seeds rich in omega-3: chia, flax, and perilla
Sargi, S. C., Silva, B. C. E., dos Santos, H. M. C., Montanher, P. F., Boeing, J. S., Santos, O. O., de Souza, N. E., & Visentainer, J. V. (2013) · Food Science and Technology · doi:10.1590/s0101-20612013005000057 · Cited by 182
Srichuwong, S., Curti, D., Austin, S., King, R., Lamothe, L. M., & Gloria, H. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.04.019 · Cited by 178
Chicco, A. G., D’Alessandro, M. E., Hein, G. J., Oliva, M. E., & Lombardo, Y. B. (2008) · British Journal Of Nutrition · doi:10.1017/s000711450899053x · Cited by 175
Olivos-Lugo, B. L., Valdivia-López, M. A., & Tecante, A. (2010) · Food Science and Technology International · doi:10.1177/1082013209353087 · Cited by 175
Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats
Poudyal, H., Panchal, S. K., Ward, L. C., & Brown, L. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.07.014 · Cited by 173
Campos, M. R. S., Salazar‐Vega, I. M., Chel‐Guerrero, L., & Betancur‐Ancona, D. (2012) · LWT · doi:10.1016/j.lwt.2012.07.017 · Cited by 166
Chia (Salvia hispanica L) Gel Can Be Used as Egg or Oil Replacer in Cake Formulations
Borneo, R., Aguirre, A., & León, A. E. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.03.011 · Cited by 161
Antioxidant potential of dietary chia seed and oil ( Salvia hispanica L.) in diet-induced obese rats
Marineli, R. D. S., Lenquiste, S. A., Moraes, É. A., & Maróstica, M. R. (2015) · Food Research International · doi:10.1016/j.foodres.2015.07.039 · Cited by 157
Cotabarren, J., Rosso, A. M., Tellechea, M., García-Pardo, J., Rivera, J. L., Obregón, W. D., & Parisi, M. G. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2018.09.061 · Cited by 155
Kampa, M., Nistikaki, A., Tsaousis, V., Maliaraki, N. E., Notas, G., & Castanas, E. (2002) · BMC Clinical Pathology · doi:10.1186/1472-6890-2-3 · Cited by 152
Ottesen, M., & Svendsen, I. (1970) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(70)19014-8 · Cited by 152
Supplementation of Milled Chia Seeds Increases Plasma ALA and EPA in Postmenopausal Women
Jin, F., Nieman, D. C., Sha, W., Xie, G., Qiu, Y., & Jia, W. P. (2012) · Plant Foods for Human Nutrition · doi:10.1007/s11130-012-0286-0 · Cited by 147
Chia seed does not promote weight loss or alter disease risk factors in overweight adults
Nieman, D. C., Cayea, E. J., Austin, M. D., Henson, D. A., McAnulty, S. R., & Jin, F. (2009) · Nutrition Research · doi:10.1016/j.nutres.2009.05.011 · Cited by 146
In Vivo Packaging of Triacylglycerols Enhances Arabidopsis Leaf Biomass and Energy Density
Winichayakul, S., Scott, R., Roldan, M. B., Hatier, J. B., Livingston, S., Cookson, R., Curran, A., & Roberts, N. J. (2013) · PLANT PHYSIOLOGY · doi:10.1104/pp.113.216820 · Cited by 144
Lopez (2015) · doi:10.1016/bs.afnr.2015.06.002 · Cited by 142
Design, Development and Construct Validation of the Children’s
Khan, S., Wirth, M. D., Ortaglia, A., Alvarado, C. R., Shivappa, N., Hurley, T. G., & Hébert, J. R. (2018) · Scholar Commons (University of South Carolina) · Cited by 135
Vuksan, V. V. V., Jenkins, A. L., Dias, A. G., Lee, A. S., Jovanovski, E., Rogovik, A. L., & Hanna, A. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2009.159 · Cited by 128
INTESTINAL ASSIMILATION OF INTACT PEPTIDES AND PROTEINS FROM THE DIET‐A NEGLECTED FIELD?
Gardner, M. L. G. (1984) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1984.tb00708.x · Cited by 125
Vuksan, V., Jenkins, A. L., Brissette, C., Choleva, L., Jovanovski, E., Gibbs, A. L., Bazinet, R. P., Au-Yeung, F., Zurbau, A., Ho, H. V. T., et al. (2017) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2016.11.124 · Cited by 125
Yoshikawa, M. (2015) · Peptides · doi:10.1016/j.peptides.2015.07.013 · Cited by 120
Montoya‐Rodríguez, A., Gómez-Favela, M. A., Reyes‐Moreno, C., Milán‐Carrillo, J., & de Mejı́a, E. G. (2015) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12125 · Cited by 117
Ayerza, R. (2009) · Journal of Oleo Science · doi:10.5650/jos.58.347 · Cited by 112
Nutrition value and use of grain amaranth: potential future application in bread making
Mlakar, S. G., Turinek, M., Jakop, M., Bavec, M., & Bavec, F. (2009) · Agricultura · Cited by 109
Orona‐Tamayo, D., Valverde, M. E., Nieto-Rendón, B., & Paredes‐López, O. (2015) · LWT · doi:10.1016/j.lwt.2015.05.033 · Cited by 108
Evaluation of performance of dough and bread incorporating chia (Salvia hispanica L.)
Iglesias-Puig, E., & Haros, C. M. (2013) · European Food Research and Technology · doi:10.1007/s00217-013-2067-x · Cited by 108
Vuksan, V. V. V., Choleva, L., Jovanovski, E., Jenkins, A. L., Au‐Yeung, F., Dias, A. G., Ho, H. V. T., Zurbau, A., & Duvnjak, L. S. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.148 · Cited by 105
Chia Flour Supplementation Reduces Blood Pressure in Hypertensive Subjects
Toscano, L. T., da Silva, C. S. O., Toscano, L. T., de Almeida, A. E. M., da Cruz Santos, A., & Silva, A. S. (2014) · Plant Foods for Human Nutrition · doi:10.1007/s11130-014-0452-7 · Cited by 104
Chia Seed Supplementation and Disease Risk Factors in Overweight Women: A Metabolomics Investigation
Nieman, D. C., Gillitt, N., Jin, F., Henson, D. A., Kennerly, K., Shanely, R. A., Ore, B., Su, M., & Schwartz, S. (2012) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2011.0443 · Cited by 104
Marineli, R. D. S., Moura, C. S., Moraes, É. A., Lenquiste, S. A., Lollo, P. C. B., Morato, P. N., Amaya‐Farfán, J., & Maróstica, M. R. (2014) · Nutrition · doi:10.1016/j.nut.2014.11.009 · Cited by 97
Quantitative assessment of placental morphology may identify specific causes of stillbirth
Ptacek, I., Smith, A. H., Garrod, A., Bullough, S., Bradley, N., Batra, G., Sibley, C. P., Jones, R. L., Brownbill, P., & Heazell, A. E. P. (2016) · BMC Clinical Pathology · doi:10.1186/s12907-016-0023-y · Cited by 97
Samani, Z. N., Sewell, R. D. E., Lorigooini, Z., & Rafieian‐Kopaei, M. (2018) · Current Diabetes Reports · doi:10.1007/s11892-018-1042-0 · Cited by 94
Ellulu, M. S. (2017) · Inflammopharmacology · doi:10.1007/s10787-017-0314-7 · Cited by 93
Wet‐fractionation of Phaseolus lunatus seeds: partial characterization of starch and protein
Betancur‐Ancona, D., Tintoré, S. G., & Chel‐Guerrero, L. (2004) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.1804 · Cited by 92
Ayerza, R., & Coates, W. E. (2009) · Industrial Crops and Products · doi:10.1016/j.indcrop.2009.03.009 · Cited by 90
Peptides from Chia Present Antibacterial Activity and Inhibit Cholesterol Synthesis
Coelho, M. S., Soares-Freitas, R. A. M., Arêas, J. A. G., Gandra, E. A., & Salas-Mellado, M. D. L. M. (2018) · Plant Foods for Human Nutrition · doi:10.1007/s11130-018-0668-z · Cited by 89
Gómez-Favela, M. A., Gutiérrez‐Dorado, R., Cuevas‐Rodríguez, E. O., Canizalez-Román, V. A., León-Sicairos, C., Milán‐Carrillo, J., & Reyes‐Moreno, C. (2017) · Plant Foods for Human Nutrition · doi:10.1007/s11130-017-0631-4 · Cited by 88
da Silva, B. P., Dias, D. M., Moreira, M. E. D. C., Toledo, R. C. L., da Matta, S. L. P., Lúcia, C. M. D., Martino, H. S. D., & Pinheiro-Sant’Ana, H. M. (2016) · Plant Foods for Human Nutrition · doi:10.1007/s11130-016-0543-8 · Cited by 87
Genetic diversity among varieties of Chia (Salvia hispanica L.)
Joseph, C. P. (2004) · Genetic Resources and Crop Evolution · doi:10.1023/b:gres.0000034583.20407.80 · Cited by 86
Campos, M. R. S., González, F. P., Chel‐Guerrero, L., & Betancur‐Ancona, D. (2013) · International Journal of Food Science · doi:10.1155/2013/158482 · Cited by 81
Ho, H. V. T., Lee, A. S., Jovanovski, E., Jenkins, A. L., deSouza, R., & Vuksan, V. V. V. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2013.103 · Cited by 76
Sandri, L. T. B., dos Santos, F. G., Fratelli, C., & Capriles, V. D. (2017) · Food Science & Nutrition · doi:10.1002/fsn3.495 · Cited by 76
(2017) · PubMed · Cited by 76
Rossi, A., Oliva, M. E., Ferreira, M. D. R., Chicco, A. G., & Lombardo, Y. B. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512003558 · Cited by 74
Bioinformatics study of delta-12 fatty acid desaturase 2 (FAD2) gene in oilseeds
Nayeri, F. D., & Yarizade, K. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3373-5 · Cited by 66
Udenigwe, C. C., Okolie, C. L., Qian, H., Ohanenye, I. C., Agyei, D., & Aluko, R. E. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.09.001 · Cited by 66
Toscano, L. T., Toscano, L. T., Tavares, R. L., Silva, C. S. D. O., & Silva, A. S. (2014) · PubMed · doi:10.3305/nh.2015.31.3.8242 · Cited by 64
Xue, Y., Chen, B., Win, A. N., Fu, C. M., Lian, J., Liu, X., Wang, R., Zhang, X., & Chai, Y. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191432 · Cited by 62
Novel α-Tubulin Mutations Conferring Resistance to Dinitroaniline Herbicides in Lolium rigidum
Chu, Z., Chen, J., Nyporko, A. Y., Han, H., Yu, Q. P., & Powles, S. B. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00097 · Cited by 59
Creus, A., Ferreira, M., Oliva, M., & Lombardo, Y. B. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5020018 · Cited by 57
Levent, H. (2017) · Journal of Food Science and Technology · doi:10.1007/s13197-017-2633-5 · Cited by 56
Chañi, E. M. M., Pacheco, S. O. D. S., Martínez, G. A., Freitas, M. R., Ivona, J. G., Ivona, J. A., Craig, W. J., & Pacheco, F. J. (2018) · Nutrients · doi:10.3390/nu10070922 · Cited by 55
Effects of chia (Salvia hispanica L.) on calcium bioavailability and inflammation in Wistar rats
da Silva, B. P., Toledo, R. C. L., Grancieri, M., Moreira, M. E. D. C., Medina, N. R., Silva, R. R., Costa, N. M. B., & Martino, H. S. D. (2018) · Food Research International · doi:10.1016/j.foodres.2018.08.078 · Cited by 52
Rendón–Villalobos, R., Ortíz-Sánchez, A., Solorza‐Feria, J., & Hernandez, C. A. T. (2012) · Czech Journal of Food Sciences · doi:10.17221/393/2010-cjfs · Cited by 51
Vázquez-Ovando, A., Rosado-Rubio, J. G., Chel‐Guerrero, L., & Betancur‐Ancona, D. (2010) · CyTA - Journal of Food · doi:10.1080/19476330903223580 · Cited by 50
Meyer, B. J., & de Groot, R. H. M. (2017) · Nutrients · doi:10.3390/nu9121305 · Cited by 49
Ahmad, B. S., Talou, T., Straumīte, E., Šabovics, M., Krūma, Z., Saad, Z., Hijazi, A., & Merah, O. (2018) · Foods · doi:10.3390/foods7090135 · Cited by 49
Haslam, S. A., Reicher, S. D., & Millard, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0109015 · Cited by 48
Ayaz, A., Akyol, A., Eroglu, E. I., Çetin, A. K., Samur, G., & Akbıyık, F. (2017) · Nutrition Research and Practice · doi:10.4162/nrp.2017.11.5.412 · Cited by 44
Sreedhar, R. V., Kumari, P., Rupwate, S. D., Rajasekharan, R., & Srinivasan, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123580 · Cited by 43
Gupta, S. K., Yadav, B. S., Raj, U., Freilich, S., & Varadwaj, P. K. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01025 · Cited by 42
Park, J., Lee, S. Y., Kim, W. Y., Jung, Y. J., Chae, H. B., Jung, H. S., Kang, C. H., Shin, M. R., Kim, S. Y., Su’udi, M., et al. (2011) · New Phytologist · doi:10.1111/j.1469-8137.2011.03734.x · Cited by 40
Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis
Rasheed, A., & Cummins, C. L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082307 · Cited by 40
Zeng, H., Xie, Y., Liu, G., Lin, D., He, C., & Shi, H. (2018) · Plant Molecular Biology · doi:10.1007/s11103-018-0733-x · Cited by 39
Ferreira, C. D. S., Fomes, L. D. F. D. S., da Silva, G. E. S., & Rosa, G. (2015) · PubMed · doi:10.3305/nh.2015.32.5.9394 · Cited by 38
Radovanovic, N., Thambugala, D., Duguid, S. D., Loewen, E., & Cloutier, S. (2014) · Molecular Biotechnology · doi:10.1007/s12033-014-9737-1 · Cited by 36
Vázquez-Ovando, A., Betancur‐Ancona, D., & Chel‐Guerrero, L. (2012) · CyTA - Journal of Food · doi:10.1080/19476337.2012.692123 · Cited by 33
Thongnak, L., Pongchaidecha, A., Jaikumkao, K., Chatsudthipong, V., Chattipakorn, N., & Lungkaphin, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-13206-5 · Cited by 33
Kaneko, K., Mizushige, T., Miyazaki, Y., Lazarus, M., Urade, Y., Yoshikawa, M., Kanamoto, R., & Ohinata, K. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00405.2013 · Cited by 31
Sharma, A., & Chauhan, R. S. (2012) · Comparative and Functional Genomics · doi:10.1155/2012/914843 · Cited by 31
A Bifunctional Enzyme That Has Both Monoacylglycerol Acyltransferase and Acyl Hydrolase Activities
Vijayaraj, P., Jashal, C. B., Vijayakumar, A., Sapa, H., Rao, D. K. V., & Rajasekharan, R. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.202135 · Cited by 30
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Metadata
- Authors
- Grancieri, M., Martino, H. S. D., & Gonzalez de Mejia, E.
- Affiliations
- Universidade Federal de Viçosa (BR)
- Dept. de Nutrição e Saúde Univ. Federal de Viçosa Viçosa MG Brazil
- Dept. of Food Science & Human Nutrition Univ. of Illinois at Urbana‐Champaign IL U.S.A
- Venue
- Comprehensive Reviews in Food Science and Food Safety
- Publisher
- Wiley
- Published
- 2019-02-12
- Volume
- 18
- Issue
- 2
- Pages
- 480-499
- ISSN
- 1541-4337 (ISSN-L)
- OpenAlex
- W2913105102
- Cited by
- 238
- References
- 119
- Citations by year
- 2026: 32 · 2025: 39 · 2024: 30 · 2023: 42 · 2022: 33 · 2021: 31 · 2020: 23 · 2019: 7
- FWCI
- 7.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Comprehensive Reviews in Food Science and Food Safety (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior”- Brazil (001)
- ACES International Joint Research Program, University of Illinois [Research was supported by the USDA-NIFA-HATCH project (1014457)
- Conselho Nacional de Ciência e Tecnologia Brasileira (200739/2017-4)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
- Keywords
- Salvia hispanica, bioactive peptides, omega-3 fatty acids, essential amino acids, DPP-4 inhibitors, ACE inhibitors, antioxidant capacity, hypoglycemic effect, antihypertensive effect, health benefits
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