Cited by 115Gastrointestinal motility and disordersProbiotics and Fermented FoodsGut microbiota and health

Probiotics for childhood functional gastrointestinal disorders: a systematic review and meta-analysis

Korterink, Judith J, Ockeloen, Lize, Benninga, Marc A, Tabbers, Merit M, Hilbink, Mirrian, Deckers‐Kocken, Judith M·2014·Acta Paediatrica

Abstract

UNLABELLED: A systematic review and meta-analysis were performed to investigate the quantity and quality of the current evidence regarding the effect of different probiotic strains in the treatment of functional gastrointestinal disorders (FGID) in children and adolescents. CONCLUSION: Probiotics are more effective than placebo in the treatment of patients with abdominal pain-related FGID, especially with respect to patients with irritable bowel syndrome. To date, however, probiotics have not proved effective for children with functional constipation.

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Crossref · 10.1111/apa.12513

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37 of 37 references verified0 citation errors · 0 not checkable

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  • Similar studies with pediatric patients do not support the efficacy of probiotics on pediatric functional constipation.

    “However, similar studies with pediatric patients do not support the efficacy of probiotics on pediatric FC [ 85 , 86 ].”

    From Role of gut microbiota in functional constipation (2021) · cites this paper as [85]

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Authors
Korterink, J. J., Ockeloen, L., Benninga, M. A., Tabbers, M. M., Hilbink, M., & Deckers‐Kocken, J. M.
Affiliations
  • Jeroen Bosch Ziekenhuis (NL)
  • Amsterdam UMC Location University of Amsterdam (NL)
Corresponding author
Korterink, Judith J
Venue
Acta Paediatrica
Publisher
Wiley
Published
2014-01-07
Volume
103
Issue
4
Pages
365-372
ISSN
  • 0365-1436 (ISSN-L)
  • 0803-5253
  • 1651-2227
OpenAlex
W1965957847
Cited by
115
References
37
Citations by year
2026: 5 · 2025: 5 · 2024: 2 · 2023: 9 · 2022: 10 · 2021: 12 · 2020: 9 · 2019: 8 · 2018: 10 · 2017: 14 · 2016: 11 · 2015: 12 · 2014: 8
FWCI
1.64
Type
journal article
Language
en
Open access
closed
Locations
  • Acta Paediatrica (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
probiotics, functional gastrointestinal disorders, childhood, irritable bowel syndrome, abdominal pain, functional constipation, probiotic strains, adolescents, placebo comparison
MeSH terms
Adolescent, Child, Child, Preschool, Gastrointestinal Diseases, Humans, Infant, Probiotics

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