The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Dental biofilm infections – an update
Open accessAbstract
Teeth are colonized by oral bacteria from saliva containing more than 700 different bacterial species. If removed regularly, the dental biofilm mainly comprises oral streptococci and is regarded as resident microflora. But if left undisturbed, a complex biofilm containing up to 100 bacterial species at a site will build up and may eventually cause development of disease. Depending on local ecological factors, the composition of the dental biofilm may vary considerably. With access to excess carbohydrates, the dental biofilm will be dominated by mainly gram‐positive carbohydrate‐fermenting bacteria causing demineralization of teeth, dental caries, which may further lead to inflammation and necrosis in the pulp and periapical region, i.e., pulpitis and periapical periodontitis. In supra‐ and subgingival biofilms, predominantly gram‐negative, anaerobic proteolytic bacteria will colonize and cause gingival inflammation and breakdown of supporting periodontal fibers and bone and ultimately tooth loss, i.e., gingivitis, chronic or aggressive periodontitis, and around dental implants, peri‐implantitis. Furthermore, bacteria from the dental biofilm may spread to other parts of the body by bacteremia and cause systemic disease. Basically, prevention and treatment of dental biofilm infections are achieved by regular personal and professional removal of the dental biofilm.
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Cites
Microbial complexes in subgingival plaque
Socransky, S. S., Haffajee, A. D., Cugini, M. A., Smith, C., & Kent, R. L. (1998) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1998.tb02419.x · Cited by 5,050
Habib, G., Lancellotti, P., Antunes, M. J., Bongiorni, M. G., Casalta, J.-P., Del Zotti, F., Dulgheru, R., El Khoury, G., Erba, P. A., Iung, B., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv319 · Cited by 4,997
Dewhirst, F. E., Chen, T., Izard, J., Paster, B. J., Tanner, A. C. R., Yu, W.-H., Lakshmanan, A., & Wade, W. G. (2010) · Journal of Bacteriology · doi:10.1128/jb.00542-10 · Cited by 3,352
Defining the normal bacterial flora of the oral cavity
Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., & Dewhirst, F. E. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5721-5732.2005 · Cited by 3,092
Effect of material characteristics and/or surface topography on biofilm development
Teughels, W., Van Assche, N., Sliepen, I., & Quirynen, M. (2006) · Clinical Oral Implants Research · doi:10.1111/j.1600-0501.2006.01353.x · Cited by 1,358
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Biofilms, the customized microniche
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Bacteria of Dental Caries in Primary and Permanent Teeth in Children and Young Adults
Aas, J. A., Griffen, A. L., Dardis, S. R., Lee, A. M., Olsen, I., Dewhirst, F. E., Leys, E. J., & Paster, B. J. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.01410-07 · Cited by 952 · cited 1×
“they are acidogenic and aciduric and actually involved in the caries process remains to be determined (12).”
BackgroundBacterial interactions and successions during plaque development
Kolenbrander, P. E., Palmer, R. J., Rickard, A. H., Jakubovics, N. S., Chalmers, N. I., & Diaz, P. I. (2006) · Periodontology 2000 · doi:10.1111/j.1600-0757.2006.00187.x · Cited by 791
Inflammation and Bone Loss in Periodontal Disease
Cochran, D. L. (2008) · Journal of Periodontology · doi:10.1902/jop.2008.080233 · Cited by 732
Cited by
Fasoulas, A., Pavlidou, E., Petridis, D., Mantzorou, M., Seroglou, K., & Giaginis, C. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02064 · Cited by 51
Characterization of Scardovia wiggsiae Biofilm by Original Scanning Electron Microscopy Protocol
Bossù, M., Selan, L., Artini, M., Relucenti, M., Familiari, G., Papa, R., Vrenna, G., Spigaglia, P., Barbanti, F., Salucci, A., et al. (2020) · Microorganisms · doi:10.3390/microorganisms8060807 · Cited by 50
Antimicrobial effects of a stannous fluoride toothpaste in distinct oral microenvironments
Haraszthy, V. I., Raylae, C. C., & Sreenivasan, P. K. (2019) · The Journal of the American Dental Association · doi:10.1016/j.adaj.2019.01.007 · Cited by 34
Dumitru, C. N., Mariana, L., Budacu, C. C., Mitea, G., Radu, M. D., Dumitru, A. O., Lupoae, A., Tatu, A., & Topor, G. (2025) · Dentistry Journal · doi:10.3390/dj13050222 · Cited by 17
Metadata
- Authors
- Larsen, T., & Fiehn, N.
- Venue
- APMIS
- Publisher
- Wiley
- Published
- 2017-04
- Volume
- 125
- Issue
- 4
- Pages
- 376-384
- ISSN
- 0903-4641 (ISSN-L)
- 1600-0463
- OpenAlex
- W2605771163
- Cited by
- 365
- References
- 28
- FWCI
- 37.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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