Dopamine receptors –IUPHAR R eview 13

Repeated cocaine administration changes the function and subcellular distribution of adenosine A1receptor in the rat nucleus accumbens

Toda, S., Alguacil, L. F., & Kalivas, P. W. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02121.x · Cited by 69

Schizophrenia in Translation: Dissecting Motivation in Schizophrenia and Rodents

Simpson, E. H., Waltz, J. A., Kellendonk, C., & Balsam, P. D. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs114 · Cited by 67

Nicotine-Induced Structural Plasticity in Mesencephalic Dopaminergic Neurons Is Mediated by Dopamine D3 Receptors and Akt-mTORC1 Signaling

Collo, G., Bono, F., Cavalleri, L., Plebani, L., Mitola, S. M. F., Pich, E. M., Millan, M. J., Zoli, M., Maskos, U., Spano, P., et al. (2013) · Molecular Pharmacology · doi:10.1124/mol.113.084863 · Cited by 67

Dopamine D2-like receptor signaling suppresses human osteoclastogenesis

Hanami, K., Nakano, K., Saito, K., Okada, Y., Yamaoka, K., Kubo, S., Kondo, M., & Tanaka, Y. (2013) · Bone · doi:10.1016/j.bone.2013.04.019 · Cited by 66

Signaling Pathways Leading to Phosphorylation of Akt and GSK-3β by Activation of Cloned Human and Rat Cerebral D2 and D3 Receptors

la Cour, C. M., Salles, M., Pasteau, V., & Millan, M. J. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.065409 · Cited by 66

Involvement of a Subpopulation of Neuronal M4Muscarinic Acetylcholine Receptors in the Antipsychotic-like Effects of the M1/M4Preferring Muscarinic Receptor Agonist Xanomeline

Dencker, D., Wörtwein, G., Weikop, P., Jeon, J., Thomsen, M., Sager, T. N., Mørk, A., Woldbye, D. P. D., Wess, J., & Fink‐Jensen, A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0370-11.2011 · Cited by 65

Fluorescence Studies Reveal Heterodimerization of Dopamine D1and D2Receptors in the Plasma Membrane

Dziedzicka‐Wasylewska, M., Faron‐Górecka, A., Andrecka, J., et al. (2006) · Biochemistry · doi:10.1021/bi060702m · Cited by 65

A physiological role for the dopamine D5 receptor as a regulator of BDNF and Akt signalling in rodent prefrontal cortex

Perreault, M. L., Jones-Tabah, J., O’Dowd, B. F., & George, S. R. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712000685 · Cited by 65

Confocal analysis of cholinergic and dopaminergic inputs onto pyramidal cells in the prefrontal cortex of rodents

Zhang (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00021 · Cited by 65

DRD4 Genotype Predicts Longevity in Mouse and Human

Grady, D. L., Thanos, P. K., Corrada, M. M., Barnett, J. C., Ciobanu, V., Shustarovich, D., Napoli, A., Moyzis, A. G., Grandy, D. K., Rubinstein, M., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3515-12.2013 · Cited by 63

ERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertion

Song, R. S., Massenburg, B. B., Wenderski, W., Jayaraman, V., Thompson, L. E., & Neves, S. R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311783110 · Cited by 63

Protein kinase Cβ is a modulator of the dopamine D2 autoreceptor‐activated trafficking of the dopamine transporter

Chen, R., Daining, C. P., Sun, H., Fraser, R., Stokes, S. L., Leitges, M., & Gnegy, M. E. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12229 · Cited by 61

PKC phosphorylates GluA1-Ser831 to enhance AMPA receptor conductance

Jenkins, M. A., & Traynelis, S. F. (2012) · Channels · doi:10.4161/chan.18648 · Cited by 60

Selective Overexpression of Dopamine D3 Receptors in the Striatum Disrupts Motivation but not Cognition

Simpson, E. H., Winiger, V., Biezonski, D. K., Haq, I., Kandel, E. R., & Kellendonk, C. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.11.023 · Cited by 59

Signaling in Striatal Neurons

Girault, J. (2012) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-396456-4.00006-7 · Cited by 57

Dopamine D4 Receptors in Psychostimulant Addiction

Ciano, P. D., Grandy, D. K., & Foll, B. L. (2014) · Advances in pharmacology · doi:10.1016/b978-0-12-420118-7.00008-1 · Cited by 57

Functionally Selective Dopamine D2/D3Receptor Agonists Comprising an Enyne Moiety

Hiller, C., Kling, R. C., Heinemann, F. W., Meyer, K., Hübner, H., & Gmeiner, P. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm400520c · Cited by 55

Reciprocal Modulation of Function between the D1 and D2 Dopamine Receptors and the Na+,K+-ATPase

Hazelwood, L. A., Free, R. B., Cabrera, D. M., Skinbjerg, M., & Sibley, D. R. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805520200 · Cited by 54

Regulation of the Pcl7–Pho85 cyclin–cdk complex by Pho81

Lee, M., O'regan, S., Moreau, J. ‐., Johnson, A. L., Johnston, L. H., & Goding, C. R. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.02140.x · Cited by 54

Peripherin‐mediated death of motor neurons rescued by overexpression of neurofilament NF‐H proteins

Beaulieu, J., & Julien, J. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01653.x · Cited by 53

D1Dopamine Receptor Coupling to PLCβ Regulates Forward Locomotion in Mice

Medvedev, I. O., Ramsey, A. J., Masoud, S. T., Bermejo, M. K., Urs, N. M., Sotnikova, T. D., Beaulieu, J., Gainetdinov, R. R., & Salahpour, A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2382-13.2013 · Cited by 53

Selective Disruption of Dopamine D2 Receptors in Pituitary Lactotropes Increases Body Weight and Adiposity in Female Mice

Millan, M. I. P., Luque, G. M., Ramirez, M. C., Noaín, D., Ornstein, A. M., Rubinstein, M., & Becú‐Villalobos, D. (2014) · Endocrinology · doi:10.1210/en.2013-1707 · Cited by 52

Deficient Dopamine D2 Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

Zhang, Y., Cuevas, S., Asico, L. D., Escano, C. S., Yang, Y., Pascua, A., Wang, X., Jones, J. E., Grandy, D. K., Eisner, G. M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038745 · Cited by 52

Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization

Wu, J., McCallum, S. E., Glick, S. D., & Huang, Y. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.10.041 · Cited by 52

Insulin, IGF-1, and Muscarinic Agonists Modulate Schizophrenia-associated Genes in Human Neuroblastoma Cells

Altar, C. A., Hunt, R. A., Jurata, L. W., Webster, M. J., Derby, E. G., Gallagher, P., Lemire, A. L., Brockman, J. A., & Laeng, P. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.08.031 · Cited by 50

Direct and indirect interactions of the dopamine D3 receptor with glutamate pathways: implications for the treatment of schizophrenia

Sokoloff, P., Leriche, L., Díaz, J., Louvel, J., & Pumain, R. (2012) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-012-0797-0 · Cited by 49

Nearest neighbor analysis of dopamine D1 receptors and Na+‐K+‐ATPases in dendritic spines dissected by STED microscopy

Blom, H., Rönnlund, D., Scott, L., Špicarová, Z., Rantanen, V., Widengren, J., Aperia, A. C., & Brismar, H. (2011) · Microscopy Research and Technique · doi:10.1002/jemt.21046 · Cited by 47

Pre‐synaptic dopamine D3receptor mediates cocaine‐induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways

Collo, G., Bono, F., Cavalleri, L., Plebani, L., Pich, E. M., Millan, M. J., Spano, P., & Missale, C. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07618.x · Cited by 46

Dual alteration of limbic dopamine D1 receptor‐mediated signalling and the Akt/GSK3 pathway in dopamine D3 receptor mutants during the development of methamphetamine sensitization

Chen, P., Lao, C. L., & Chen, J. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04203.x · Cited by 46

Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1

Bonito-Oliva, A., Pallottino, S., Bertran‐Gonzalez, J., Girault, J., Valjent, E., & Fisone, G. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.043 · Cited by 44

Persistent activation of the D1R/Shp-2/Erk1/2 pathway in l-DOPA-induced dyskinesia in the 6-hydroxy-dopamine rat model of Parkinson's disease

Fiorentini, C., Savoia, P., Savoldi, D., Barbon, A., & Missale, C. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.01.005 · Cited by 44

Dopamine D2 Receptor-mediated Epidermal Growth Factor Receptor Transactivation through a Disintegrin and Metalloprotease Regulates Dopaminergic Neuron Development via Extracellular Signal-related Kinase Activation

Yoon, S., & Baik, J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.461202 · Cited by 41

Each Individual Isoform of the Dopamine D2 Receptor Protects from Lactotroph Hyperplasia

Radl, D. B., Mei, C. D., Chen, E., Lee, H., & Borrelli, E. (2013) · Molecular Endocrinology · doi:10.1210/me.2013-1008 · Cited by 40

Possible mechanisms for the skeletal effects of antipsychotics in children and adolescents

Calarge, C. A., Ivins, S. D., Motyl, K. J., Shibli-Rahhal, A. A., Bliziotes, M. M., & Schlechte, J. (2013) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125313487548 · Cited by 39

SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C

Lee, S. M., Kant, A., Blake, D. C., Murthy, V., Boyd, K. N., Wyrick, S. D., & Mailman, R. B. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.05.042 · Cited by 39

Rescue of Dopamine Transporter Function in Hypoinsulinemic Rats by a D2Receptor–ERK-Dependent Mechanism

Owens, W. A., Williams, J. M., Saunders, C., Avison, M. J., Galli, A., & Daws, L. C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3759-11.2012 · Cited by 39

Adenosine A1 and Dopamine D1 Receptor Regulation of AMPA Receptor Phosphorylation and Cocaine-Seeking Behavior

Hobson, B. D., O’Neill, C. E., Levis, S. C., Monteggia, L. M., Neve, R. L., Self, D. W., & Bachtell, R. K. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.96 · Cited by 36

The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin signaling network and the control of normal myelopoiesis.

Martelli, A. M., Chiarini, F., Evangelisti, C., Grimaldi, C., Ognibene, A., Manzoli, L., Billi, A. M., & McCubrey, J. A. (2010) · PubMed · doi:10.14670/hh-25.669 · Cited by 35

Qualitative and quantitative re‐evaluation of epidermal growth factor‐ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target‐derived neurotrophic signaling (Part 1)

Iwakura, Y., Zheng, Y., Sibilia, M. C., Abe, Y., Piao, Y., Yokomaku, D., Wang, R., Ishizuka, Y., Takei, N., & Nawa, H. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07287.x · Cited by 35

The adenosine A2A receptor agonist CGS 21680 exhibits antipsychotic-like activity in Cebus apella monkeys

Andersen, M. B., Fuxé, K., Werge, T. M., et al. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200212000-00005 · Cited by 35

Dopamine D4 receptor oligomerization – contribution to receptor biogenesis

Van Craenenbroeck, K., Borroto‐Escuela, D. O., Romero‐Fernandez, W., Skieterska, K., Rondou, P., Lintermans, B., Vanhoenacker, P., Fuxe, K., Ciruela, F., & Haegeman, G. (2011) · The FEBS Journal · doi:10.1111/j.1742-4658.2011.08052.x · Cited by 33

Daily oscillation of gene expression in the retina is phase-advanced with respect to the pineal gland

Bai, L., Zimmer, S., Rickes, O., Rohleder, N. H., Holthues, H., Engel, L., Leube, R. E., & Spessert, R. (2008) · Brain Research · doi:10.1016/j.brainres.2008.01.073 · Cited by 33

Novel therapies for the management of type 2 diabetes mellitus: Part 1. Pramlintide and bromocriptine‐ QR (2型糖尿病治疗新药：第1部分.普兰林肽与溴隐亭‐QR)

Grunberger, G. (2013) · Journal of Diabetes · doi:10.1111/1753-0407.12034 · Cited by 32

Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S

Neve, K. A., Ford, C., Buck, D. C., Grandy, D. K., Neve, R. L., & Phillips, T. J. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.06.035 · Cited by 31

The tyrosine phosphatase Shp‐2 interacts with the dopamine D1 receptor and triggers D1‐mediated Erk signaling in striatal neurons

Fiorentini, C., Mattanza, C., Collo, G., Savoia, P., Spano, P., & Missale, C. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07196.x · Cited by 30

Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes

Yamada, T., Katagiri, H., Asano, T., Tsuru, M., Inukai, K., Ono, H., Kodama, T., Kikuchi, M., & Oka, Y. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00486.2001 · Cited by 30

Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840

Jenkins, M. A., Wells, G., Bachman, J., Snyder, J. P., Jenkins, A., Huganir, R. L., Oswald, R. E., & Traynelis, S. F. (2014) · Molecular Pharmacology · doi:10.1124/mol.113.091488 · Cited by 30

Regulation of the ERK pathway in the dentate gyrus by in vivo dopamine D1 receptor stimulation requires glutamatergic transmission

Gangarossa, G., & Valjent, E. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.062 · Cited by 27

Newer antipsychotics and upcoming molecules for schizophrenia

George, M., Amrutheshwar, R., Rajkumar, R. P., Kattimani, S., & Dkhar, S. A. (2013) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-013-1498-4 · Cited by 27

mGlu5R promotes glutamate AMPA receptor phosphorylation via activation of PKA/DARPP-32 signaling in striatopallidal medium spiny neurons

Dell’Anno, M. T., Pallottino, S., & Fisone, G. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.03.025 · Cited by 25

Glycogen Synthase Kinase-3 Overexpression Replicates Electroretinogram Anomalies of Offspring at High Genetic Risk for Schizophrenia and Bipolar Disorder

Lavoie, J., Hébert, M., & Beaulieu, J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.08.035 · Cited by 24

BRET Approaches to Characterize Dopamine and TAAR1 Receptor Pharmacology and Signaling

Espinoza, S., Masri, B., Salahpour, A., & Gainetdinov, R. R. (2012) · Methods in molecular biology · doi:10.1007/978-1-62703-251-3_8 · Cited by 24

Hyperdopaminergic modulation of inhibitory transmission is dependent on GSK‐3β signaling‐mediated trafficking of GABAA receptors

Li, Y., Wang, M., & Gao, W. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07790.x · Cited by 23

Mechanism of action of clozapine in the context of dopamine D1-D2 receptor hetero-dimerization--a working hypothesis.

Dziedzicka‐Wasylewska, M., Faron‐Górecka, A., Górecki, A., & Kuśemider, M. (2008) · PubMed · Cited by 23

Dopamine D2 Receptor Relies upon PPM/PP2C Protein Phosphatases to Dephosphorylate Huntingtin Protein

Marion, S., Urs, N. M., Peterson, S. M., Sotnikova, T. D., Beaulieu, J., Gainetdinov, R. R., & Caron, M. G. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.544312 · Cited by 20

A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer

Trincavelli, M. L., Daniele, S., Orlandini, E., Navarro, G., Casadó, V., Giacomelli, C., Nencetti, S., Nuti, E., Macchia, M., Huebner, H., et al. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.12.018 · Cited by 18

Negative regulation of cyclin-dependent kinase 5 targets by protein kinase C

Sahin, B., Hawasli, A. H., Greene, R. W., Molkentin, J. D., & Bibb, J. A. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.061 · Cited by 17

Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia

Tan, M. L., Basu, D., Kwiecień, J. M., Johnson, R. L., & Mishra, R. K. (2013) · Peptides · doi:10.1016/j.peptides.2013.02.004 · Cited by 17

Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization

Basu, D., Tian, Y., Bhandari, J., Jiang, J. R., Hui, P., Johnson, R. L., & Mishra, R. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070736 · Cited by 17

How adenylate cyclase choreographs the pas de deux of the receptors heteromerization dance

Woods, A. S., & Jackson, S. N. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.02.006 · Cited by 15

Frequency of Hyperprolactinemia and Its Associations With Demographic and Clinical Characteristics and Antipsychotic Medications in Psychiatric Inpatients in China

Wang, Z., Xiang, Y., An, F., Correll, C. U., Ungvari, G. S., Wang, C., Lai, K. Y. C., Bo, Q., Li, Y., Zhong, B., et al. (2013) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12050 · Cited by 15

Dopamine: Functions, Signaling, and Association with Neurological Diseases

Klein, M. O., Battagello, D. S., Cardoso, A. R., Hauser, D. N., Bittencourt, J. C., & Correa, R. G. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0632-3 · Cited by 1,073

An update on the physiological and therapeutic relevance of GPCR oligomers

Farran, B. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.01.008 · Cited by 115

Locus Coeruleus and Dopamine-Dependent Memory Consolidation

Yamasaki, M., & Takeuchi, T. (2017) · Neural Plasticity · doi:10.1155/2017/8602690 · Cited by 91

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

Ramos‐Lopez, O., Riezu‐Boj, J. I., Milagro, F. I., Martinez, J. A., & MENA Project (2018) · Brain and Behavior · doi:10.1002/brb3.1017 · Cited by 33

Dopamine Concentrations and Dopamine Receptor Gene Expression in Emotion-Related Brain Structures of Female Adult Rats Exposed to Stress of Chronic Isolation from Weaning

Karailiev, P., Hlavacova, N., Chomanic, P., Riecansky, I., & Jezova, D. (2020) · General Physiology and Biophysics · doi:10.4149/gpb_2020015 · Cited by 3