Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications

Prospective identification of tumorigenic breast cancer cells

Al‐Hajj, M., Wicha, M. S., Benito‐Hernández, A., Morrison, S. J., & Clarke, M. F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530291100 · Cited by 10,579

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Lapidot, T., Sirard, C., Vormoor, J., Murdoch, B., Hoang, T., Caceres-Cortes, J., Minden, M., Paterson, B., Caligiuri, M. A., & Dick, J. E. (1994) · Nature · doi:10.1038/367645a0 · Cited by 4,783

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

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Identification and expansion of human colon-cancer-initiating cells

Ricci‐Vitiani, L., Lombardi, D. G., Pilozzi, E., Biffoni, M., Todaro, M., Peschle, C., & Maria, R. D. (2006) · Nature · doi:10.1038/nature05384 · Cited by 4,001

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium

Sato, T., Stange, D. E., Ferrante, M., Vries, R. G. J., van Es, J. H., van den Brink, S., van Houdt, W. J., Pronk, A., van Gorp, J., Siersema, P. D., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.07.050 · Cited by 3,753

Modeling Development and Disease with Organoids

Clevers, H. (2016) · Cell · doi:10.1016/j.cell.2016.05.082 · Cited by 3,196

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

Clarke, M. F., Dick, J. E., Dirks, P. B., Eaves, C., Jamieson, C., Jones, D. L., Visvader, J., Weissman, I. L., & Wahl, G. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-3126 · Cited by 3,124

The third dimension bridges the gap between cell culture and live tissue

Pampaloni, F., Reynaud, E. G., & Stelzer, E. H. K. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2236 · Cited by 2,817

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cellsPreprint

Dontu, G., Abdallah, W. M., Foley, J. M., Jackson, K. W., Clarke, M. F., Kawamura, M., & Wicha, M. S. (2003) · Genes & Development · doi:10.1101/gad.1061803 · Cited by 2,413

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Lee, J., Kotliarova, S. E., Kotliarov, Y., Li, A., Su, Q., Donin, N. M., Pastorino, S., Purow, B. W., Christopher, N., Zhang, W., et al. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.03.030 · Cited by 2,345

Role of circulating tumor cell spheroids in drug resistance

Hamilton, G., & Rath, B. (2019) · Cancer Drug Resistance · doi:10.20517/cdr.2019.47 · Cited by 35

Diphenylbutylpiperidine Antipsychotic Drugs Inhibit Prolactin Receptor Signaling to Reduce Growth of Pancreatic Ductal Adenocarcinoma in Mice

Dandawate, P. R., Kaushik, G., Ghosh, C., Standing, D., Sayed, A. A. A., Choudhury, S., Subramaniam, D., Manzardo, A. M., Banerjee, T., Santra, S., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.11.279 · Cited by 35

Ex Vivo Culture Models to Indicate Therapy Response in Head and Neck Squamous Cell Carcinoma

Demers, I., Donkers, J., Kremer, B., & Speel, E. M. (2020) · Cells · doi:10.3390/cells9112527 · Cited by 35

Cu( ii )-BODIPY photosensitizer for CAIX overexpressed cancer stem cell therapy

Jung, H. S., Koo, S., Won, M., An, S., Park, H., Sessler, J. L., Han, J., & Kim, J. S. (2023) · Chemical Science · doi:10.1039/d2sc03945a · Cited by 37

Millimetre-deep micrometre-resolution vibrational imaging by shortwave infrared photothermal microscopy

Ni, H., Yuan, Y., Li, M., Zhu, Y., Ge, X., Yin, J., Dessai, C. V. P., Wang, L., & Cheng, J. (2024) · Nature Photonics · doi:10.1038/s41566-024-01463-6 · Cited by 34

Cancer stem cells in neuroblastoma therapy resistance

Aravindan, N., Jain, D., Somasundaram, D. B., Herman, E. S., & Aravindan, S. (2019) · Cancer Drug Resistance · doi:10.20517/cdr.2019.72 · Cited by 35

The Organoid Era Permits the Development of New Applications to Study Glioblastoma

Andreatta, F., Beccaceci, G., Fortuna, N., Celotti, M., Felice, D. D., Lorenzoni, M., Foletto, V., Genovesi, S., Rubert, J., & Alaimo, A. (2020) · Cancers · doi:10.3390/cancers12113303 · Cited by 36

Microgel Single-Cell Culture Arrays on a Microfluidic Chip for Selective Expansion and Recovery of Colorectal Cancer Stem Cells

Lin, D., Chen, X., Liu, Y., Lin, Z., Luo, Y., Fu, M., Yang, N., Liu, D., & Cao, J. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c02335 · Cited by 34

Emerging roles of lncRNA in Nasopharyngeal Carcinoma and therapeutic opportunities

Wang, H., Wang, W., & Fan, S. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.70292 · Cited by 34

Microbeam evolution: from single cell irradiation to pre-clinical studies

Ghita, M., Fernández-Palomo, C., Fukunaga, H., Fredericia, P. M., Schettino, G., Bräuer‐Krisch, E., Butterworth, K. T., McMahon, S. J., & Prise, K. M. (2018) · International Journal of Radiation Biology · doi:10.1080/09553002.2018.1425807 · Cited by 34

Radiosensitization with Gadolinium Chelate-Coated Gold Nanoparticles Prevents Aggressiveness and Invasiveness in Glioblastoma

Durand, M., Chateau, A., Jubréaux, J., Devy, J., Paquot, H., Laurent, G., Bazzi, R., Roux, S., Richet, N., Reinhard, A., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s375918 · Cited by 36

Investigation of multicellular tumor spheroids enriched for a cancer stem cell phenotype

Herheliuk, T., Perepelytsina, O. M., Ugnivenko, A. P., Остапченко, Л. І., & Sydorenko, M. (2019) · Stem Cell Investigation · doi:10.21037/sci.2019.06.07 · Cited by 32

Polymer Thin Film-Induced Tumor Spheroids Acquire Cancer Stem Cell-like Properties

Choi, M., Yu, S. J., Choi, Y., Lee, H. R., Lee, E., Lee, E., Lee, Y., Song, J., Son, J. G., Lee, T. G., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-0927 · Cited by 32

HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma

Jaeger, M. D. C., Ghisleni, E. C., Cardoso, P. S., Siniglaglia, M., Falcón, T., Brunetto, A. T., Brunetto, A. L., de Farias, C. B., Taylor, M. D., Nör, C., et al. (2020) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01505-y · Cited by 32

Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening

Goričan, L., Gole, B., & Potočnik, U. (2020) · Cells · doi:10.3390/cells9071707 · Cited by 32

Precision Medicine Gains Momentum: Novel 3D Models and Stem Cell-Based Approaches in Head and Neck Cancer

Affolter, A., Lammert, A., Kern, J., Scherl, C., & Rotter, N. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.666515 · Cited by 34

Impact of Cancer Stem Cells on Therapy Resistance in Gastric Cancer

Otaegi-Ugartemendia, M., Matheu, A., & Carrasco‐García, E. (2022) · Cancers · doi:10.3390/cancers14061457 · Cited by 32

Pre-clinical models for studying the interaction between mesenchymal stromal cells and cancer cells and the induction of stemness

Avnet, S., Lemma, S., Cortini, M., Di Pompo, G., Perut, F., & Baldini, N. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00305 · Cited by 29

Bispecific aptamer-decorated and light-triggered nanoparticles targeting tumor and stromal cells in breast cancer derived organoids: implications for precision phototherapies

Camorani, S., Caliendo, A., Morrone, E., Agnello, L., Martini, M., Cantile, M., Cerrone, M., Zannetti, A., Deda, M. L., Fedele, M., et al. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03014-x · Cited by 31

WASH overexpression enhances cancer stem cell properties and correlates with poor prognosis of esophageal carcinoma

Huang, L., Lian, J., Chen, X., Qin, G., Zheng, Y., & Zhang, Y. (2017) · Cancer Science · doi:10.1111/cas.13400 · Cited by 31

Scaffold-free 3D culture systems for stem cell-based tissue regeneration

Liu, K.-C., Chen, Y.-C., Hsieh, C.-F., Wang, M., Zhong, M.-X., & Cheng, N. (2024) · APL Bioengineering · doi:10.1063/5.0225807 · Cited by 38

Human fibroblast-macrophage tissue spheroids demonstrate ratio-dependent fibrotic activity for in vitro fibrogenesis model development

Tan, Y. J., Suarez, A., Garza, M., Khan, A., Elisseeff, J. H., & Coon, D. (2020) · Biomaterials Science · doi:10.1039/c9bm00900k · Cited by 32

lncMat2B regulated by severe hypoxia induces cisplatin resistance by increasing DNA damage repair and tumor-initiating population in breast cancer cells

García-Venzor, A., Mandujano-Tinoco, E. A., Ruiz-Silvestre, A., Sánchez-López, J. M., Lizárraga, F., Zampedri, C., Meléndez-Zajgla, J., & Maldonado, V. (2020) · Carcinogenesis · doi:10.1093/carcin/bgaa078 · Cited by 29

ZIP4 Is a Novel Cancer Stem Cell Marker in High-Grade Serous Ovarian Cancer

Fan, Q., Zhang, W., Emerson, R. E., & Xu, Y. (2020) · Cancers · doi:10.3390/cancers12123692 · Cited by 30

A rapid biofabrication technique for self-assembled collagen-based multicellular and heterogeneous 3D tissue constructs

Shahin‐Shamsabadi, A., & Selvaganapathy, P. R. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.05.024 · Cited by 31

The role of metabolic reprogramming in cancer metastasis and potential mechanism of traditional Chinese medicine intervention

Wang, D., Wang, F., Kong, X., Li, Q., Shi, H., Zhao, S., Li, W., Li, Y., & Meng, J. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113376 · Cited by 32

Application of Three-dimensional (3D) Tumor Cell Culture Systems and Mechanism of Drug Resistance

Shehzad, A., Ravinayagam, V., AlRumaih, H. S., Aljafary, M. A., Almohazey, D., Almofty, S. A., Al-Rashid, N. A., & Al-Suhaimi, E. A. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666191014163923 · Cited by 28

Stearoyl-CoA desaturase 1 as a therapeutic target for cancer: a focus on hepatocellular carcinoma

Raeisi, M., Hassanbeigi, L., Khalili, F., Kharrati‐Shishavan, H., Yousefi, M., & Mehdizadeh, A. (2022) · Molecular Biology Reports · doi:10.1007/s11033-021-07094-2 · Cited by 28

Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses

Ammons, D. T., Guth, A., Rozental, A. J., Kurihara, J. N., Marolf, A. J., Chow, L., Griffin, J. F., Makii, R. L., MacQuiddy, B., Boss, M., et al. (2022) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0388 · Cited by 28

Multicellular tumor spheroids: A convenient in vitro model for translational cancer research

Patel, T. C., & Jain, N. D. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.123184 · Cited by 34

An Effective Primary Head and Neck Squamous Cell Carcinoma In Vitro Model

Oppel, F., Shao, S., Schürmann, M., Goon, P. K. C., Albers, A. E., & Sudhoff, H. H. (2019) · Cells · doi:10.3390/cells8060555 · Cited by 27

Synthetic switch-based baculovirus for transgene expression control and selective killing of hepatocellular carcinoma cells

Lin, M., Tseng, Y.-W., Shen, C., Hsu, M., Hwu, J. R., Chang, C.-W., Yeh, C.-J., Chou, M., Wu, J., & Hu, Y. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky447 · Cited by 26

Gel-Free 3D Tumoroids with Stem Cell Properties Modeling Drug Resistance to Cisplatin and Imatinib in Metastatic Colorectal Cancer

Sogawa, C. A., Eguchi, T., Namba, Y., Okusha, Y., Aoyama, E., Ohyama, K., & Okamoto, K. (2021) · Cells · doi:10.3390/cells10020344 · Cited by 26

Cancer Stem Cell Traits in Tumor Spheres Derived from Primary Laryngeal Carcinoma Cell Lines

Kumbar, V., Muddapur, U. M., Bhat, K. G., Shwetha, H., Kugaji, M. S., Peram, M. R., & Dindawar, S. (2021) · Contemporary Clinical Dentistry · doi:10.4103/ccd.ccd_252_20 · Cited by 28

CCR7 Mediates TGF-β1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial–Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway

Zheng, Y., Miu, Y., Yang, X., Yang, X., & Zhu, M. (2017) · DNA and Cell Biology · doi:10.1089/dna.2017.3818 · Cited by 26

Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines

Ameri, W. A., Ahmed, I., Al-Dasim, F. M., Mohamoud, Y. A., Al-Azwani, I. K., Malek, J. A., & Karedath, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143568 · Cited by 28

Deep learning unlocks label-free viability assessment of cancer spheroids in microfluidics

Chiang, C., Anne, R., Chawla, P. A., Shaw, R. M., He, S., Rock, E. C., Zhou, M., Cheng, J., Gong, Y., & Chen, Y. (2024) · Lab on a Chip · doi:10.1039/d4lc00197d · Cited by 26

The Evolution of Anticancer 3D In Vitro Models: The Potential Role of Machine Learning and AI in the Next Generation of Animal-Free Experiments

Momoli, C., Costa, B., Lenti, L., Tubertini, M., Parenti, M., Martella, E., Varchi, G., & Ferroni, C. (2025) · Cancers · doi:10.3390/cancers17040700 · Cited by 24

Hormonal Regulation of Patient-Derived Endometrial Cancer Stem-like Cells Generated by Three-Dimensional Culture

Shiba, S., Ikeda, K., SUZUKI, T. A., Shintani, D., Okamoto, K., Horie‐Inoue, K., Hasegawa, K., & Inoue, S. (2019) · Endocrinology · doi:10.1210/en.2019-00362 · Cited by 24

Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties

Pasquale, V., Ducci, G., Campioni, G., Ventrici, A., Assalini, C., Busti, S., Vanoni, M., Vago, R., & Sacco, E. (2020) · Cells · doi:10.3390/cells9122669 · Cited by 25

Small Molecule Targeting of Oxysterol-Binding Protein (OSBP)-Related Protein 4 and OSBP Inhibits Ovarian Cancer Cell Proliferation in Monolayer and Spheroid Cell Models

Bensen, R. C., Gunay, G., Finneran, M. C., Jhingan, I., Acar, H., & Burgett, A. W. G. (2021) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00207 · Cited by 24

Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence

Song, S., Ma, D., Xu, L., Wang, Q., Liu, L., Tong, X., & Yan, H. (2021) · iScience · doi:10.1016/j.isci.2021.103558 · Cited by 24

CD73 and PD-L1 as Potential Therapeutic Targets in Gallbladder Cancer

Cao, L., Bridle, K. R., Shrestha, R., Prithviraj, P., Crawford, D. H., & Jayachandran, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031565 · Cited by 24

A novel copper chelator for the suppression of colorectal cancer

Shi, X., Li, Y., Jia, M., Zhang, Z., Huang, L., Zhang, M., Xun, Q., Jiang, D., & Liu, Y. (2023) · Drug Development Research · doi:10.1002/ddr.22034 · Cited by 24

Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

Prasad, S., Chandra, A., Cavo, M., Parasido, E., Fricke, S., Lee, Y., D’Amone, E., Gigli, G., Albanese, C., Rodriguez, O., et al. (2020) · Nanotechnology · doi:10.1088/1361-6528/abc208 · Cited by 23

Comparison of primary and passaged tumor cell cultures and their application in personalized medicine

Pipiya, V. V., Gilazieva, Z. E., Issa, S. S., Rizvanov, A. A., & Solovyeva, V. V. (2024) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2024.00237 · Cited by 23

Patient-Derived Organoids: A Game-Changer in Personalized Cancer Medicine

Abbasian, M. H., Sobhani, N., Sisakht, M. M., D’Angelo, A., Sirico, M., & Roudi, R. (2024) · Stem Cell Reviews and Reports · doi:10.1007/s12015-024-10805-4 · Cited by 28

Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

Hernández-Camarero, P., López‐Ruiz, E., Griñán‐Lisón, C., García, M. Á., Chocarro‐Wrona, C., Marchal, J. A., Kenyon, J., & Perán, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-47837-7 · Cited by 23

Extracellular vesicle-associated miR-135b and -135a regulate stemness in Group 4 medulloblastoma cells by targeting angiomotin-like 2

Choi, S. A., Koh, E. J., Kim, R. N., Byun, J. W., Phi, J. H., Yang, J., Wang, K., Park, A. K., Hwang, D. W., Lee, J. Y., et al. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01645-6 · Cited by 24

Role of autophagy in regulation of glioma stem cells population during therapeutic stress

Abbas, S., Singh, S. K., Saxena, A. K., Tiwari, S., Sharma, L. K., & Tiwari, M. (2020) · Journal of Stem Cells and Regenerative Medicine · doi:10.46582/jsrm.1602012 · Cited by 23

Ca 2+ ‐activated K + channel K Ca 1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models

Ohya, S., Kajikuri, J., Endo, K., Kito, H., Elboray, E. E., & Suzuki, T. (2021) · Cancer Science · doi:10.1111/cas.15046 · Cited by 23

Spheroid-induced heterogeneity and plasticity of uveal melanoma cells

Chen, Y., Lu, X., Gao, L., Dean, D. C., & Liu, Y. (2022) · Cellular Oncology · doi:10.1007/s13402-022-00671-y · Cited by 23

Electrochemical Detection of a Novel Pt(IV) Prodrug with the Metronidazole Axial Ligand in the Hypoxic Area

Spector, D. V., Erofeev, A. S., Gorelkin, P. V., Vaneev, A. N., Akasov, R., Ul’yanovskii, N. V., Nikitina, V. N., Semkina, A. S., Vlasova, K. Y., Soldatov, M. A., et al. (2022) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.2c02062 · Cited by 23

Towards a New 3Rs Era in the construction of 3D cell culture models simulating tumor microenvironment

Zhang, L., Liao, W., Chen, S., Chen, Y., Cheng, P., Lu, X., & Ma, Y. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1146477 · Cited by 24

Synergistic Encapsulation of Paclitaxel and Sorafenib by Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles for Ovarian Cancer Therapy

Jin, C. E., Yoon, M. S., Jo, M. J., Kim, S. Y., Lee, J. M., Kang, S. J., Park, C., Kim, J., & Shin, D. H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041206 · Cited by 23

The m6A methyltransferase RBM15 affects tumor cell stemness and progression of cervical cancer by regulating the stability of lncRNA HEIH

Quan, Y., Zhou, M., Li, J., Yang, Y., Guo, J., Tang, T., & Liu, P. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.113924 · Cited by 23

Molecular iodine inhibits the expression of stemness markers on cancer stem-like cells of established cell lines derived from cervical cancer

Ordóñez, G. D. B., Ortíz-Sánchez, E., Chalma, P. R., Valencia-González, H. A., Aceves, C., & García-Carrancá, A. M. (2018) · BMC Cancer · doi:10.1186/s12885-018-4824-5 · Cited by 23

Human Organoids and Their Application in Tumor Models, Disease Modeling, and Tissue Engineering

Song, S., Liu, Z., Wang, Y., & Gong, B. (2025) · Medicine Bulletin · doi:10.1002/mdb2.70001 · Cited by 25

Polymersome‐assisted delivery of curcumin: A suitable approach to decrease cancer stemness markers and regulate miRNAs expression in HT29 colorectal cancer cells

Pakizehkar, S., Ranji, N., Sohi, A. N., & Sadeghizadeh, M. (2019) · Polymers for Advanced Technologies · doi:10.1002/pat.4759 · Cited by 22

A novel 3D co-culture platform for integrating tissue interfaces for tumor growth, migration and therapeutic sensitivity: “PP-3D-S”

Garakani, M. M., Ahangar, P., Watson, S., Nisol, B., Wertheimer, M. R., Rosenzweig, D. H., & Ajji, A. (2021) · Biomaterials Advances · doi:10.1016/j.msec.2021.112566 · Cited by 22

Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics

Konishi, I., Abiko, K., Hayashi, T., Yamanoi, K., Murakami, R., Yamaguchi, K. D., Hamanishi, J., Baba, T., Matsumura, N., & Mandai, M. (2022) · Journal of Gynecologic Oncology · doi:10.3802/jgo.2022.33.e83 · Cited by 21

Construction of cancer-on-a-chip for drug screening

Liu, Y., Yang, Q., Zhang, H., Han, S., Liu, N., Ren, H. J., Guo, H., & Xu, F. (2021) · Drug Discovery Today · doi:10.1016/j.drudis.2021.03.006 · Cited by 22

Wogonin Influences Osteosarcoma Stem Cell Stemness Through ROS-dependent Signaling

Koh, H., Sun, H., Xing, Z., Liu, R., Chandimali, N., Kwon, T., & Lee, D. (2020) · In Vivo · doi:10.21873/invivo.11878 · Cited by 21

Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization

Governa, V., Hugo Talbot, A., de Oliveira, K. G., Cerezo-Magaña, M., Bång-Rudenstam, A., Johansson, M. C., Månsson, A., Forsberg‐Nilsson, K., Marko‐Varga, G., Pérez, J. E., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2114456119 · Cited by 20

Models of head and neck squamous cell carcinoma using bioengineering approaches

Bonartsev, A. P., Lei, B., Kholina, M. S., Menshikh, K. A., Svyatoslavov, D. S., Ивановна, С. С., Sinelnikov, M. Y., Voinova, V. V., Шайтан, К. В., Kirpichnikov, M. P., et al. (2022) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2022.103724 · Cited by 23

Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen

Harrop, R., O’Neill, E. E., & Stern, P. L. (2019) · Therapeutic Advances in Vaccines and Immunotherapy · doi:10.1177/2515135518821623 · Cited by 22

Enrichment of genes associated with squamous differentiation in cancer initiating cells isolated from urothelial cells transformed by the environmental toxicant arsenite

Hoggarth, Z. E., Osowski, D. B., Slusser-Nore, A., Shrestha, S., Pathak, P., Solseng, T., Garrett, S. H., Patel, D. H., Savage, E. M., Sens, D. A., et al. (2019) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2019.04.021 · Cited by 21

BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas

Fisher, M. L., Balinth, S., Hwangbo, Y., Wu, C., Ballon, C., Wilkinson, J. E., Goldberg, G. L., & Mills, A. A. (2021) · Cancer Research · doi:10.1158/0008-5472.can-21-0707 · Cited by 21

Models in Pancreatic Neuroendocrine Neoplasms: Current Perspectives and Future Directions

Forsythe, S. D., Pu, T., Andrews, S. G., Madigan, J. P., & Sadowski, S. M. (2023) · Cancers · doi:10.3390/cancers15153756 · Cited by 23

Molecularly engineered lipid droplet-targeted NIR-II type I AIE photosensitizers trigger ferroptosis and apoptosis for cancer therapy

Yang, L., Zhuang, J., Chen, J., Wu, X., Li, N., & Zhao, N. (2025) · Science China Materials · doi:10.1007/s40843-025-3483-5 · Cited by 20

Comparison of EMT-Related and Multi-Drug Resistant Gene Expression, Extracellular Matrix Production, and Drug Sensitivity in NSCLC Spheroids Generated by Scaffold-Free and Scaffold-Based Methods

Qi, X., Prokhorova, A. V., Mezentsev, A., Shen, N., Trofimenko, A. V., Filkov, G. I., Sulimanov, R. A., Makarov, V., & Durymanov, M. O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113306 · Cited by 22

Rational design of a ratiometric fluorescent probe for imaging lysosomal nitroreductase activity

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Circular RNA ZNF800 (hsa_circ_0082096) regulates cancer stem cell properties and tumor growth in colorectal cancer

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