Behavioural and Neurochemical Consequences of Early Weaning in Rodents

Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress

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Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

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Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat

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Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

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Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

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Maternal care, hippocampal synaptogenesis and cognitive development in rats

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Adult brain neurogenesis and psychiatry: a novel theory of depression

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MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder

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Long-term behavioral and neuroendocrine adaptations to adverse early experience

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Maternal care and the development of stress responses

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Early life experience alters response of adult neurogenesis to stress

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Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation.

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Influence of Neonatal Rearing Conditions on Stress‐Induced Adrenocorticotropin Responses and Norepinepherine Release in the Hypothalamic Paraventricular Nucleus

Liu, Caldji, Sharma, Plotsky, & Meaney (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00422.x · Cited by 456

Periodic Maternal Deprivation Induces Gender-Dependent Alterations in Behavioral and Neuroendocrine Responses to Emotional Stress in Adult Rats

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Agonistic Behavior of Mice and Rats: A Review

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Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats

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Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression: Characterization of Intracellular Mediators and Potential Genomic Target Sites

Weaver, I. C. G., Diorio, J. C., Seckl, J. R., Szyf, M., & Meaney, M. J. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1321.099 · Cited by 332

Maternal Care, Gene Expression, and the Development of Individual Differences in Stress Reactivity

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Anxiety and fear behaviors in adult male and female C57BL/6 mice are modulated by maternal separation

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Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formation

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The influence of natural variations in maternal care on play fighting in the rat

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Aggression heightened by alcohol or social instigation in mice: reduction by the 5-HT1B receptor agonist CP-94,253

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Psychosocial stress, glucocorticoids, and structural alterations in the tree shrew hippocampus

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Aggression Escalated by Social Instigation or by Discontinuation of Reinforcement (“Frustration”) in Mice Inhibition by Anpirtoline: A 5-HT1B Receptor Agonist

de Almeida, R. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00291-9 · Cited by 149

Early weaning induces anxiety and precocious myelination in the anterior part of the basolateral amygdala of male Balb/c mice

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Maternal Behavior Regulates Benzodiazepine/GABAA Receptor Subunit Expression in Brain Regions Associated with Fear in BALB/c and C57BL/6 Mice

Caldji, C., Diorio, J. C., Anisman, H., & Meaney, M. J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300436 · Cited by 145

Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice

Kikusui, T., Ichikawa, S., & Mori, Y. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.12.009 · Cited by 115

Play in the domestic cat is enhanced by rationing of the mother during lactation

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Weaning in rats: I. Maternal behavior

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Early weaning deprives mouse pups of maternal care and decreases their maternal behavior in adulthood

Kikusui, T., Isaka, Y., & Mori, Y. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.03.013 · Cited by 100

Multidimensional structure of anxiety-related behavior in early-weaned rats

Kanari, K., Kikusui, T., Takeuchi, Y., & Mori, Y. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.05.008 · Cited by 90

Early weaning augments neuroendocrine stress responses in mice

Kikusui, T., Nakamura, K., Kakuma, Y., & Mori, Y. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.007 · Cited by 85

Repeated maternal separation: differences in cocaine-induced behavioral sensitization in adult male and female mice

Kikusui, T., Faccidomo, S., & Miczek, K. A. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1989-1 · Cited by 83

Deprivation of mother–pup interaction by early weaning alters myelin formation in male, but not female, ICR mice

Kikusui, T., Kiyokawa, Y., & Mori, Y. (2006) · Brain Research · doi:10.1016/j.brainres.2006.11.031 · Cited by 78

Study of expression of myelin basic proteins (MBPs) in developing rat brain using a novel antibody reacting with four major isoforms of MBP

Akiyama, K., Ichinose, S., Omori, A., Sakurai, Y., & Asou, H. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10188 · Cited by 64

Effects of early weaning on anxiety and autonomic responses to stress in rats

Ito, A., Kikusui, T., Takeuchi, Y., & Mori, Y. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.03.023 · Cited by 62

Differences in maternal behavior of rats and the sociosexual development of the offspring

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The influence of nutrition and postpartum mating on weaning and subsequent play behaviour of hooded rats

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∂-Opioid modulation of social interactions in juvenile mice weaned at different ages

Terranova, M. L., & Giovanni Laviola, A. (2001) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00447-4 · Cited by 49

Effects of cohabitation with females on aggressive behavior between male mice

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Early separation of young rats from the mother and the development of play fighting

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Early weaning decreases play‐fighting behavior during the postweaning developmental period of wistar rats

Shimozuru, M., Kodama, Y., Iwasa, T., Kikusui, T., Takeuchi, Y., & Mori, Y. (2007) · Developmental Psychobiology · doi:10.1002/dev.20202 · Cited by 44

Changes in social instigation- and food restriction-induced aggressive behaviors and hippocampal 5HT1B mRNA receptor expression in male mice from early weaning

Nakamura, K., Kikusui, T., TAKEUCHI, Y., & MORI, Y. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.10.002 · Cited by 43

Effects of mother-litter separation on survival, growth, and brain amino acid levels

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The Influence of Early Weaning on Aggressive Behavior in Mice

Nakamura, K., Kikusui, T., Takeuchi, Y., & Mori, Y. (2003) · Journal of Veterinary Medical Science · doi:10.1292/jvms.65.1347 · Cited by 29

Epigenetic transmission of the impact of early stress across generations

Franklin, T. B., Russig, H., Weiss, I. C., Gräff, J., Linder, N., Michalon, A., Vizi, S., & Mansuy, I. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.036 · Cited by 1,125

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

Heim, C., & Binder, E. B. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.032 · Cited by 986

A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing

Tottenham, N. (2009) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.068.2009 · Cited by 651

Elevated amygdala response to faces following early deprivation

Tottenham, N., Hare, T. A., Millner, A., Gilhooly, T., Zevin, J. D., & Casey, B. J. (2011) · Developmental Science · doi:10.1111/j.1467-7687.2010.00971.x · Cited by 468

Larger amygdala but no change in hippocampal volume in 10-year-old children exposed to maternal depressive symptomatology since birth

Lupien, S. J., Parent, S., Evans, A. C., Tremblay, R. E., Zelazo, P. D., Corbo, V., Pruessner, J. C., & Séguin, J. R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105371108 · Cited by 379

Emotionality-Related Consequences of Early Weaning in Mice and Rats

Kikusui, T. (2011) · Neuromethods · doi:10.1007/978-1-61779-313-4_14 · Cited by 2

Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice

Kikusui, T. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/conf.neuro.08.2009.09.191 · Cited by 2

Early weaning augments neuroendocrine stress responses in mice

Kikusui, T., Nakamura, K., Kakuma, Y., & Mori, Y. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.007 · Cited by 85

A review of the behavioral and neurochemical consequences of early weaning in rodents

Kikusui, T., Nakamura, K., & Mori, Y. (2007) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2007.03.019 · Cited by 18

Early weaning induces anxiety and aggression in adult mice

Kikusui, T., Takeuchi, Y., & Mori, Y. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2003.12.016 · Cited by 103