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Tobacco smoking behaviors in bipolar disorder: a comparison of the general population, schizophrenia, and major depression
Abstract
OBJECTIVES: This study compared the prevalence of tobacco smoking behaviors in patients with bipolar disorder with normal and psychiatric (schizophrenia and major depression) controls. The main goal was to establish that bipolar patients smoke more than normal controls. Differences with psychiatric controls were explored. METHODS: Samples of 424 patients (99 bipolar, 258 schizophrenia and 67 major depression) and 402 volunteer controls were collected in Central Kentucky. Smoking data for Kentucky's general population were available. Odds ratios (ORs) and their 95% confidence intervals (CIs) were used to establish the strength of associations. Logistic regression was used to adjust ORs for confounding variables. RESULTS: Using epidemiological definitions of smoking behaviors and the general population as controls provided bipolar disorder unadjusted ORs of 5.0 (95% CI: 3.3-7.8) for current cigarette smoking, 2.6 (95% CI: 1.7-4.4) for ever cigarette smoking, and 0.13 (95% CI: 0.03-0.24) for smoking cessation. Using a clinical definition and volunteers as controls provided respective bipolar disorder adjusted ORs of 7.3 (95% CI: 4.3-12.4), 4.0 (95% CI: 2.4-6.7), and 0.15 (95% CI: 0.06-0.36). Prevalences of current daily smoking for patients with major depression, bipolar disorder, and schizophrenia were 57%, 66%, and 74%, respectively. CONCLUSIONS: Bipolar disorder was associated with significantly higher prevalences of tobacco smoking behaviors compared with the general population or volunteer controls, independently of the definition used. It is possible that smoking behaviors in bipolar disorder may have intermediate prevalences between major depression and schizophrenia, but larger samples or a combination of multiple studies (meta-analysis) will be needed to establish whether this hypothesis is correct.
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“A catchment area study from Kentucky reports that the prevalence of everyday current smoking is 66% in people with BD, which is also significantly elevated when compared to the general population, and also exceeds the rate observed in people with major depression and schizophrenia (9).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [9]
Citations
Cites
Regier, D. A. (1990) · JAMA · doi:10.1001/jama.1990.03450190043026 · Cited by 3,962
Drug abuse: hedonic homeostatic dysregulation
Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535
Smoking and Mental Illness: A Population-Based Prevalence Study
Lasser, K., Boyd, J. W., Woolhandler, S., Himmelstein, D. U., McCormick, D., & Bor, D. H. (2000) · JAMA · doi:10.1001/jama.284.20.2606 · Cited by 2,508
Papageorgis, D. (1991) · Behaviour Research and Therapy · doi:10.1016/0005-7967(91)90087-j · Cited by 1,537
de Leon, J., & Diaz, F. J. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.02.010 · Cited by 1,276
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus
Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Hoff, M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.587 · Cited by 1,141
Smoking and Major Depression: A Causal Analysis
Kendler, K. S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820130038007 · Cited by 792
de León, J., Susce, M. T., Pan, R.-M., Fairchild, M., Koch, W. H., & Wedlund, P. J. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0103 · Cited by 319
Cigarette smoking and major depression
Covey, L. S., Glassman, A. H., & Stetner, F. (1998) · Journal of Addictive Diseases · doi:10.1300/j069v17n01_04 · Cited by 302
Epidemiology: Study Design and Data Analysis
Davies, S. (2006) · Journal of the American Statistical Association · doi:10.1198/jasa.2006.s92 · Cited by 288
Smoking prevalence in US birth cohorts: the influence of gender and education.
Escobedo, L. G., & Peddicord, J. P. (1996) · American Journal of Public Health · doi:10.2105/ajph.86.2.231 · Cited by 281
History of depression and smoking cessation outcome: A meta-analysis.
Hitsman, B., Borrelli, B., McChargue, D. E., Spring, B., & Niaura, R. (2003) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.71.4.657 · Cited by 253
Initiation of daily smoking and nicotine dependence in schizophrenia and mood disorders
de León, J., Díaz, F. J., Rogers, T. J., Browne, D., & Dinsmore, L. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00217-1 · Cited by 168
(1996) · PubMed · Cited by 156
de Leon, J., Becona, E., Gurpegui, M., Gonzalez-Pinto, A., & Diaz, F. J. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0911 · Cited by 144
Smoking and Vulnerability for Schizophrenia
de León, J. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.3.405 · Cited by 143
Waxmonsky, J. A., Thomas, M. R., Miklowitz, D. J., Allen, M. H., Wisniewski, S. R., Zhang, H., Ostacher, M. J., & Fossey, M. D. (2005) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2005.05.003 · Cited by 135
Tobacco Smoking and Bipolar Disorder
González-Pinto, A. M., Gutiérrez, M., Ezcurra, J., Aizpuru, F., Mosquera, F., López‐Mahía, P., & de León, J. (1998) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v59n0503 · Cited by 133
Vanable, P. A., Carey, M. P., Carey, K. B., & Maisto, S. A. (2003) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.17.4.259 · Cited by 132
Varenicline-Induced Manic Episode in a Patient With Bipolar Disorder
Kohen, I., & Kremen, N. J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07010173 · Cited by 113
de León, J., Rendon, D. M., Baca‐García, E., Aizpuru, F., González-Pinto, A. M., Anitua, C., & DÍAZ, F. J. (2007) · Alcohol and Alcoholism · doi:10.1093/alcalc/agm029 · Cited by 108
Nicotine dependence and symptoms in schizophrenia
Aguilar, M., Gurpegui, M., Diaz, F., & de Leon, J. (2005) · British Journal of Psychiatry · doi:10.1192/bjp.186.3.215 · Cited by 105
Covey, L. S., Hughes, D. C., Glassman, A. H., Blazer, D. G., & George, L. K. (1994) · Tobacco Control · doi:10.1136/tc.3.3.222 · Cited by 104
Cigarette smoking among patients with schizophrenia and bipolar disorders
Üçok, A., Polat, A., Bozkurt, O., & Meteris, H. (2004) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2004.01279.x · Cited by 85
A Brief Measure of High Nicotine Dependence for Busy Clinicians and Large Epidemiological Surveys
DÍAZ, F. J., Jané, M., Saltó, E., Pardell, H., Salleras, L., Pinet, C., & de León, J. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01538.x · Cited by 83
Predictors of Tobacco Use Among Persons With Mental Illnesses in a Statewide Population
Morris, C. D., Giese, A. A., Turnbull, J. J., Dickinson, M., & Johnson-Nagel, N. (2006) · Psychiatric Services · doi:10.1176/ps.2006.57.7.1035 · Cited by 67
Smoking Habits in Bipolar and Schizophrenic Outpatients in Southern Israel
Itkin, O., Nemets, B., & Einat, H. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n0409 · Cited by 54
Exacerbation of Recurrent Depression as a Result of Treatment With Varenicline
Popkin, M. K. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07111735 · Cited by 50
A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Disorder
Weinberger, A. H., Vessicchio, J. C., Sacco, K. A., Creeden, C. L., Chengappa, K. N. R., & George, T. P. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e318184ba3c · Cited by 47
Smoking initiation and schizophrenia: a replication study in a Spanish sample
Gurpegui, M., Martínez-Ortega, J. M., Aguilar, M. C., Díaz, F. J., Quintana, H. M., & de León, J. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2004.12.007 · Cited by 45
de León, J., Susce, M. T., DÍAZ, F. J., Rendon, D. M., & Velásquez, D. M. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1112 · Cited by 43
Does smoking reduce akathisia? Testing a narrow version of the self-medication hypothesis
de León, J., Díaz, F. J., Aguilar, M. C., Jurado, D., & Gurpegui, M. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.05.009 · Cited by 40
Bupropion SR for smoking cessation
West, R. (2003) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.4.4.533 · Cited by 36
Power and precision : a computer program for statistical power analysis and confidence intervals
Borenstein, M., Rothstein, H. R., & Cohen, J. (1997) · Medical Entomology and Zoology · Cited by 32
Severe mania following abrupt nicotine withdrawal
(1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.12.1641a · Cited by 30
Campo‐Arias, A., Díaz‐Martínez, L. A., Rueda-Jaimes, G. E., Rueda-Sánchez, M., Farelo, D., Díaz, F. J., & de León, J. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.01.001 · Cited by 26
Cigarette smoking and psychiatric disorders in Hungary
Döme, P., Ríhmer, Z., Gonda, X., Pestality, P., Kovács, G., Teleki, Z., & Mandl, P. (2005) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651500510028977 · Cited by 23
Fluoxetine, suicidal ideation, and aggressive behavior
Labbate, L. A. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.5.708b · Cited by 21
Epidemiology of Comorbid Tobacco Use and Schizophrenia: Thinking About Risks and Protective Factors
de León, J., Gurpegui, M., & Díaz, F. J. (2007) · Journal of Dual Diagnosis · doi:10.1300/j374v03n03_03 · Cited by 18
Effects of Topiramate on Smoking in Patients With Schizoaffective Disorder, Bipolar Type
Weinberger, A. H., George, T. P., Perkins, K. A., & Chengappa, K. N. R. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31816740cf · Cited by 12
A Case Report of Mania Related to Discontinuation of Bupropion Therapy for Smoking Cessation
Michael, N., Erfurth, A., & Arolt, V. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0220e · Cited by 12
Nicotine and caffeine use as confounds in psychiatric studies
Hughes, J. R., & Howard, T. S. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00344-2 · Cited by 12
Smoking Cessation in Patients With Psychiatric Disorders
Gelenberg, A. J., de León, J., Evins, A. E., Parks, J., & Rigotti, N. A. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0912 · Cited by 10
Kentucky Behavioral Risk Factor Surveillance System: 2001 Report
(2003) · PsycEXTRA Dataset · doi:10.1037/e533842010-001 · Cited by 4
Research works printed but not linked: 2
- Simon JL, 1999, Resampling Stats User’s Guide
- Labbate LA, 1992, Nicotine cessation, mania, and depression, Am J Psychiatry, 149, 708
Cited by
Sorted by citations
Yatham, L. N., Kennedy, S. H., Parikh, S. V., Schaffer, A., Beaulieu, S., Alda, M., O’Donovan, C., MacQUEEN, G. M., McIntyre, R. S., Sharma, V., et al. (2012) · Bipolar Disorders · doi:10.1111/bdi.12025 · Cited by 1,230
“Patients with BD have a fivefold higher risk of current cigarette smoking compared to the general population (300).”
BackgroundMalhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842
“Importantly, patients with bipolar disorder have a five-fold greater chance of smoking compared to the general public (Diaz et al., 2009).”
BackgroundGoldstein, B. I., Carnethon, M. R., Matthews, K. A., McIntyre, R. S., Miller, G. E., Raghuveer, G., Stoney, C. M., Wasiak, H., & McCrindle, B. W. (2015) · Circulation · doi:10.1161/cir.0000000000000229 · Cited by 519
Dickerson, F., Stallings, C. R., Origoni, A. E., Vaughan, C., Khushalani, S., Schroeder, J. R., & Yolken, R. H. (2012) · Psychiatric Services · doi:10.1176/appi.ps.201200143 · Cited by 248
Sleep and circadian functioning: critical mechanisms in the mood disorders?
Harvey, A. G. (2011) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032210-104550 · Cited by 237
“Sleep Deprivation Is Associated with Substance Use, Which May Contribute to Substance Use Comorbidity Several studies indicate that the presence of mood disorders is associated with elevated risk for alcohol abuse, drug abuse, and cigarette smoking (Diaz et al. 2009, Grant et al. 2004a).”
Background
Metadata
- Authors
- Diaz, F. J., James, D., Botts, S., Maw, L., Susce, M. T., & De Leon, J.
- Affiliations
- University of Kentucky (US)
- ORCID
- Botts, Sheila
- Venue
- Bipolar Disorders
- Publisher
- Wiley
- Published
- 2009-02-25
- Volume
- 11
- Issue
- 2
- Pages
- 154-165
- ISSN
- 1398-5647 (ISSN-L)
- 1399-5618
- OpenAlex
- W1979173012
- Cited by
- 179
- References
- 49
- Citations by year
- 2026: 6 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 12 · 2021: 6 · 2020: 10 · 2019: 8 · 2018: 6 · 2017: 12 · 2016: 6 · 2015: 20 · 2014: 6 · 2013: 12 · 2012: 24
- FWCI
- 14.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bipolar Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- smoking, bipolar disorder, schizophrenia, major depressive disorder, smoking prevalence, smoking cessation, psychiatric comorbidity
- MeSH terms
- Adult, Bipolar Disorder, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Schizophrenia, Schizophrenic Psychology, Smoking, Prevalence, Confidence Intervals, Odds Ratio, Population Groups
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