The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Role of vitamin D in the pathogenesis of type 2 diabetes mellitus
Abstract
Vitamin D deficiency has been shown to alter insulin synthesis and secretion in both humans and animal models. It has been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus. Vitamin D replenishment improves glycaemia and insulin secretion in patients with type 2 diabetes with established hypovitaminosis D, thereby suggesting a role for vitamin D in the pathogenesis of type 2 diabetes mellitus. The presence of vitamin D receptors (VDR) and vitamin D–binding proteins (DBP) in pancreatic tissue and the relationship between certain allelic variations in the VDR and DBP genes with glucose tolerance and insulin secretion have further supported this hypothesis. The mechanism of action of vitamin D in type 2 diabetes is thought to be mediated not only through regulation of plasma calcium levels, which regulate insulin synthesis and secretion, but also through a direct action on pancreatic β‐cell function. Therefore, owing to its increasing relevance, this review focuses on the role of vitamin D in the pathogenesis of type 2 diabetes mellitus.
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Cites
Vitamin D Receptor Expression in Human Muscle Tissue Decreases with Age
Bischoff-Ferrari, H., Borchers, M., Gudat, F., Dürmüller, U., Stähelin, H., & Dick, W. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2004.19.2.265 · Cited by 585
An immune origin of type 2 diabetes?
Kolb, H., & Mandrup-Poulsen, T. (2005) · Diabetologia · doi:10.1007/s00125-005-1764-9 · Cited by 394
Use of cod liver oil during pregnancy associated with lower risk of type I diabetes in the offspring
Stene, L. C., Ulriksen, J., Magnus, P., & Joner, G. (2000) · Diabetologia · doi:10.1007/s001250051499 · Cited by 362
Cited by
Obesity and vitamin Ddeficiency: a systematic review and meta‐analysis
Pereira‐Santos, M., Costa, P. R. F., Assis, A. M. O., Santos, C. A. S. T., & Santos, D. B. (2015) · Obesity Reviews · doi:10.1111/obr.12239 · Cited by 858
Vitamin D supplementation for women during pregnancy
Palacios, C., Kostiuk, L. K., & Peña-Rosas, J. P. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008873.pub4 · Cited by 377
Nikooyeh, B., Neyestani, T. R., Farvid, M., Alavi-Majd, H., Houshiarrad, A., Kalayi, A., Shariatzadeh, N., Gharavi, A., Heravifard, S., Tayebinejad, N., et al. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.007336 · Cited by 277
25-Hydroxyvitamin D levels and cognitive performance and decline in elderly men
Slinin, Y., Paudel, M. L., Taylor, B. C., Fink, H. A., Ishani, A., Canales, M. T., Yaffe, K., Barrett-Connor, E., Orwoll, E. S., Shikany, J. M., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181c7197b · Cited by 193
Vilarrasa, N., Vendrell, J., Maravall, J., Elío, I., Solano, E., San José, P., García, I., Virgili, N., Soler, J., & Gómez, J. M. (2010) · Endocrine · doi:10.1007/s12020-010-9379-4 · Cited by 110
Metadata
- Authors
- Palomer, X., González‐Clemente, J. M., Blanco‐Vaca, F., & Mauricio, D.
- Venue
- Diabetes, Obesity and Metabolism
- Publisher
- Wiley
- Published
- 2007-02-12
- Volume
- 10
- Issue
- 3
- Pages
- 185-197
- ISSN
- 1462-8902 (ISSN-L)
- 1463-1326
- OpenAlex
- W2019870128
- Cited by
- 509
- References
- 3
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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