The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Arabidopsis IRT3 is a zinc‐regulated and plasma membrane localized zinc/iron transporter
Abstract
ZIP transporters (ZRT, IRT-like proteins) are involved in the transport of iron (Fe), zinc (Zn) and other divalent metal cations. The expression of IRT3, a ZIP transporter, is higher in the Zn/cadmium (Cd) hyperaccumulator Arabidopsis halleri than is that of its ortholog in Arabidopsis thaliana, which implies a positive association of its expression with Zn accumulation in A. halleri. IRT3 genes from both A. halleri and A. thaliana functionally complemented the Zn uptake mutant Spzrt1 in Schizosaccharomyces pombe; and Zn uptake double mutant zrt1zrt2, Fe-uptake mutant fet3fet4 and conferred Zn and Fe uptake activity in Saccharomyces cerevisiae. By contrast, the manganese (Mn) uptake mutant smf1 phenotypes were not rescued. Insufficient Cd uptake for toxicity was found. Expression of IRT3-green fluorescent protein (GFP) fusion proteins in Arabidopsis root protoplasts indicated localization of both IRT3 proteins in the plasma membrane. Overexpressing AtIRT3 in A. thaliana led to increased accumulation of Zn in the shoot and Fe in the root of transgenic lines. Therefore, IRT3 functions as a Zn and Fe-uptake transporter in Arabidopsis.
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Cites
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
The ZIP family of metal transporters
Guerinot, M. L. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00138-3 · Cited by 1,200
Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4
Hanikenne, M., Talke, I. N., Haydon, M. J., Lanz, C., Nolte, A., Motte, P., Kroymann, J., Weigel, D., & Krämer, U. (2008) · Nature · doi:10.1038/nature06877 · Cited by 812
The molecular physiology of heavy metal transport in the Zn/Cd hyperaccumulator Thlaspi caerulescens
Pence, N. S., Larsen, P. B., Ebbs, S. D., Letham, D. L. D., Lasat, M. M., Garvin, D. F., Eide, D., & Kochian, L. V. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.9.4956 · Cited by 748
Becher, M., Talke, I. N., Krall, L., & Krämer, U. (2004) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01959.x · Cited by 568
Weber, M., Harada, E., Vess, C., Roepenack‐Lahaye, E. V., & Clemens, S. (2004) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01960.x · Cited by 440
Self-citationAssunção, A. G. L., Martins, P. D. C., De Folter, S., Vooijs, R., Schat, H., & Aarts, M. G. M. (2001) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2001.00666.x · Cited by 350
Bert, V., Bonnin, I., Saumitou‐Laprade, P., De Laguérie, P., & Petit, D. (2002) · New Phytologist · doi:10.1046/j.1469-8137.2002.00432.x · Cited by 257
Research works printed but not linked: 32
- Baker AJM, 1989, Terrestrial higher plants which hyperaccumulate metallic elements – a review of their distribution, ecology and phytochemistry, Biorecovery, 1, 81
- 10.1111/j.1567-1364.2008.00414.x · DOI
- 10.1093/jxb/erf004 · DOI · Paper page
- 10.1007/BF02670468 · DOI · Paper page
- 10.1021/es061432y · DOI · Paper page
- 10.1016/j.pbi.2006.03.015 · DOI · Paper page
- 10.1104/pp.103.025122 · DOI · Paper page
- 10.1105/tpc.001263 · DOI · Paper page
- 10.1016/S0269-7491(00)00203-7 · DOI
- 10.1073/pnas.93.11.5624 · DOI · Paper page
- Ernst WHO, 1974, Schwermetallvegetation der erde
- 10.1016/S0378-1119(97)00058-9 · DOI · Paper page
- 10.1073/pnas.95.12.7220 · DOI · Paper page
- 10.1093/jxb/eri317 · DOI · Paper page
- 10.1111/j.1365-313X.2005.02624.x · DOI · Paper page
- 10.1093/nar/gkm256 · DOI · Paper page
- 10.1104/pp.107.113282 · DOI
- 10.1023/A:1026438615520 · DOI · Paper page
- 10.1080/713779219 · DOI
- 10.1023/B:PLAN.0000038271.96019.aa · DOI · Paper page
- 10.1104/pp.126.4.1646 · DOI · Paper page
- 10.1074/jbc.M106754200 · DOI · Paper page
- 10.1111/j.1399-3054.1996.tb00520.x · doi:10.1111/j.1399-3054.1996.tb00520.x
- 10.1104/pp.103.026815 · DOI · Paper page
- 10.1038/scientificamerican0293-56 · DOI
- 10.1073/pnas.210214197 · DOI · Paper page
- 10.1104/pp.010820 · DOI · Paper page
- 10.1046/j.1365-313x.2000.00768.x · DOI · Paper page
- 10.1021/bi00476a001 · DOI · Paper page
- 10.1046/j.1365-313x.2001.01018.x · DOI · Paper page
- 10.1074/jbc.M309338200 · DOI · Paper page
- 10.1073/pnas.93.6.2454 · DOI · Paper page
Cited by
Metal hyperaccumulation in plants
Krämer, U. (2010) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042809-112156 · Cited by 1,284
The zinc homeostasis network of land plants
Sinclair, S. A., & Krämer, U. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.05.016 · Cited by 502
Assunção, A. G. L., Herrero, E., Lin, Y.-F., Huettel, B., Talukdar, S., Smaczniak, C., Immink, R. G. H., van Eldik, M., Fiers, M., Schat, H., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004788107 · Cited by 379
Self-citationAn overview of heavy metal challenge in plants: from roots to shoots
DalCorso, G., Manara, A., & Furini, A. (2013) · Metallomics · doi:10.1039/c3mt00038a · Cited by 325
Zinc hyperaccumulation in plants: A review
Balafrej, H., Bogusz, D., Triqui, Z.-E. A., Guedira, A., Bendaou, N., Smouni, A., & Fahr, M. (2020) · Plants · doi:10.3390/plants9050562 · Cited by 275
Metadata
- Authors
- Lin, Y., Liang, H., Yang, S., Boch, A., Clemens, S., Chen, C., Wu, J., Huang, J., & Yeh, K.
- Venue
- New Phytologist
- Publisher
- Wiley
- Published
- 2009-03-27
- Volume
- 182
- Issue
- 2
- Pages
- 392-404
- ISSN
- 0028-646X (ISSN-L)
- 1469-8137
- OpenAlex
- W2118890187
- Cited by
- 289
- References
- 8
- FWCI
- 11.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- onlinelibrary.wiley.com/termsAndConditions#vor (vor)
- doi.wiley.com/10.1002/tdm_license_1.1 (tdm)
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- Lin, Y., Liang, H., Yang, S., Boch, A., Clemens, S., Chen, C., Wu, J., Huang, J., & Yeh, K. (2009). Arabidopsis IRT3 is a zinc‐regulated and plasma membrane localized zinc/iron transporter. New Phytologist. https://doi.org/10.1111/j.1469-8137.2009.02766.x
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