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Brain region‐specific deficit in mitochondrial electron transport chain complexes in children with autism
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J. Neurochem. (2011) 117, 209–220. Mitochondria play important roles in generation of free radicals, ATP formation, and in apoptosis. We studied the levels of mitochondrial electron transport chain (ETC) complexes, that is, complexes I, II, III, IV, and V, in brain tissue samples from the cerebellum and the frontal, parietal, occipital, and temporal cortices of subjects with autism and age‐matched control subjects. The subjects were divided into two groups according to their ages: Group A (children, ages 4–10 years) and Group B (adults, ages 14–39 years). In Group A, we observed significantly lower levels of complexes III and V in the cerebellum (p < 0.05), of complex I in the frontal cortex (p < 0.05), and of complexes II (p < 0.01), III (p < 0.01), and V (p < 0.05) in the temporal cortex of children with autism as compared to age‐matched control subjects, while none of the five ETC complexes was affected in the parietal and occipital cortices in subjects with autism. In the cerebellum and temporal cortex, no overlap was observed in the levels of these ETC complexes between subjects with autism and control subjects. In the frontal cortex of Group A, a lower level of ETC complexes was observed in a subset of autism cases, that is, 60% (3/5) for complexes I, II, and V, and 40% (2/5) for complexes III and IV. A striking observation was that the levels of ETC complexes were similar in adult subjects with autism and control subjects (Group B). A significant increase in the levels of lipid hydroperoxides, an oxidative stress marker, was also observed in the cerebellum and temporal cortex in the children with autism. These results suggest that the expression of ETC complexes is decreased in the cerebellum and the frontal and temporal regions of the brain in children with autism, which may lead to abnormal energy metabolism and oxidative stress. The deficits observed in the levels of ETC complexes in children with autism may readjust to normal levels by adulthood.
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“In the cerebellum, the levels of lipid hydroperoxide [103], a product of fatty acid oxidation; of malonyldialdehyde [104], an end-product of lipid peroxidation; of 8-hydroxy-2’-deoxyguanosine (8-OH-dG) [105, 106], a marker of oxidative DNA damage; of protein carbonyl [107], a marker of protein oxidation; and of 3-nitrotyrosine [108], a marker of protein nitration, were significantly increased in”
From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [103]
In the citing paper
“Our studies of different brain regions showed that oxidative stress differentially affects selective brain regions, i.e., cerebellum, temporal and frontal cortices, in autism [103–105, 107]. Increased oxidative stress and mitochondrial abnormalities were not observed in the parietal and occipital cortices in autism [103–105, 107].”
From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [103]
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“Reduced levels of complexes III and V in the cerebellum, of complex I in the frontal cortex, and of complexes II, III, and V in the temporal cortex were observed in children with autism as compared to age-matched control subjects [103].”
From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [103]
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Citations
Cites
Mitochondrial free radical generation, oxidative stress, and aging
Cadenas, E., & Davies, K. J. A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00317-8 · Cited by 3,010
Mitochondrial Complex I Deficiency in Parkinson's Disease
Schapira, A. H. V., Cooper, J. M., Dexter, D., Clark, J. B., Jenner, P., & Marsden, C. D. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb02325.x · Cited by 2,283
MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE
Schapira, A. H. V., Cooper, J. A. D., Dexter, D. T., Jenner, P. G., Clark, J. B., & MARSDEN, C. D. (1989) · The Lancet · doi:10.1016/s0140-6736(89)92366-0 · Cited by 1,757
Histoanatomic observations of the brain in early infantile autism
Bauman, M., & Kemper, T. L. (1985) · Neurology · doi:10.1212/wnl.35.6.866 · Cited by 964
James, S. J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D. W., & Neubrander, J. A. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.6.1611 · Cited by 955
Neuroanatomic observations of the brain in autism: a review and future directions
Bauman, M. L., & Kemper, T. L. (2005) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2004.09.006 · Cited by 919
Rice, C. E. (2009) · PsycEXTRA Dataset · doi:10.1037/e562722010-001 · Cited by 762
Mitochondrial defect in Huntington's disease caudate nucleus
Gu, M., Gash, M. T., Mann, V. M., Javoy‐Agid, F., Cooper, J. M., & Schapira, A. H. V. (1996) · Annals of Neurology · doi:10.1002/ana.410390317 · Cited by 758
Chauhan, A., & Chauhan, V. (2006) · Pathophysiology · doi:10.1016/j.pathophys.2006.05.007 · Cited by 656
Self-citationEnergetic basis of brain activity: implications for neuroimaging
Shulman, R. G., Rothman, D. L., Behar, K. L., & Hyder, F. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.06.005 · Cited by 590
Lenaz, G. (2001) · IUBMB Life · doi:10.1080/15216540152845957 · Cited by 585
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes
Wegiel, J., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Marchi, E., Ma, S. Y., Chauhan, A., Chauhan, V., Bobrowicz, T. W., et al. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0655-4 · Cited by 577
Self-citationLord, C., Cook, E. H., Leventhal, B. L., & Amaral, D. G. (2000) · Neuron · doi:10.1016/s0896-6273(00)00115-x · Cited by 555
Mitochondria as a Pharmacological Target
Szewczyk, A. M., & Wojtczak, L. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.1.101 · Cited by 544
Prenatal and Perinatal Risk Factors for Autism
Kolevzon, A. L., Gross, R., & Reichenberg, A. (2007) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.161.4.326 · Cited by 541
Neuropathological findings in autism
Palmen, S. J. M. C. (2004) · Brain · doi:10.1093/brain/awh287 · Cited by 527
Effects of age on brain volume and head circumference in autism
Aylward, E., Minshew, N. J., Field, K., Sparks, B. F., & Singh, N. (2002) · Neurology · doi:10.1212/wnl.59.2.175 · Cited by 509
Minimum birth prevalence of mitochondrial respiratory chain disorders in children
Skladal, D. (2003) · Brain · doi:10.1093/brain/awg170 · Cited by 487
Mitochondrial Dysfunction and Psychiatric Disorders
Rezin, G. T., Amboni, G., Zugno, A. I., Quevedo, J., & STRECK, E. L. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9865-8 · Cited by 453
Prenatal stress and risk for autism
KINNEY, D., MUNIR, K., CROWLEY, D., & MILLER, A. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.06.004 · Cited by 440
Chauhan, A., Chauhan, V., Brown, W. T., & Cohen, I. (2004) · Life Sciences · doi:10.1016/j.lfs.2004.04.038 · Cited by 424
Self-citation(2009) · PubMed · Cited by 409
The epidemiology of mitochondrial disorders—past, present and future
Schaefer, A. M., Taylor, R. W., Turnbull, D. M., & Chinnery, P. F. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.09.005 · Cited by 406
Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
Wiedemann, F. R., Manfredi, G., Mawrin, C., Beal, M. F., & Schon, E. A. (2002) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00731.x · Cited by 383
Can Children with Autism Recover? If So, How?
Helt, M., Kelley, E., Kinsbourne, M., Pandey, J., Boorstein, H., Herbert, M., & Fein, D. (2008) · Neuropsychology Review · doi:10.1007/s11065-008-9075-9 · Cited by 353
Mitochondrial mechanisms of neural cell apoptosis
Polster, B. M., & Fiskum, G. M. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02572.x · Cited by 333
Regression and word loss in autistic spectrum disorders
Lord, C., Shulman, C., & DiLavore, P. S. (2004) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2004.t01-1-00287.x · Cited by 325
Brain development in autism: Early overgrowth followed by premature arrest of growth
Courchesne, E. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20020 · Cited by 310
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
Reddy, P. H., & Beal, M. F. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.03.004 · Cited by 294
Mitochondria: A therapeutic target in neurodegeneration
Moreira, P. I., Zhu, X., Wang, X., Lee, H., Nunomura, A., Petersen, R. B., Perry, G. L., & Smith, M. A. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.10.007 · Cited by 292
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease
Wang, X., Su, B., Zheng, L., Perry, G. L., Smith, M. A., & Zhu, X. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05867.x · Cited by 284
Juurlink, B. H. J., & Paterson, P. G. (1998) · Journal of Spinal Cord Medicine · doi:10.1080/10790268.1998.11719540 · Cited by 274
Mitochondrial dysfunction in autism spectrum disorders: a population-based study
Oliveira, G., Diogo, L. M., Grazina, M. M., Garcia, P., Ataíde, A., Marques, C., Miguel, T., Borges, L., Vicente, A., & Oliveira, C. R. (2005) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162205000332 · Cited by 267
Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis
Weissman, J. R., Kelley, R. I., Bauman, M. L., Cohen, B. H., Murray, K. F., Mitchell, R. L., Kern, R. L., & Natowicz, M. R. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003815 · Cited by 264
Course of Behavioral Change in Autism: A Retrospective Study of High-IQ Adolescents and Adults
Piven, J., HARPER, J., Palmer, P. J., & Arndt, S. V. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199604000-00019 · Cited by 256
Chromosomal disorders and autism
Gillberg, C. (1998) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1026004505764 · Cited by 237
Increased excretion of a lipid peroxidation biomarker in autism
Ming, X., Stein, T. P., Brimacombe, M., Johnson, W. G., Lambert, G. H., & Wagner, G. C. (2005) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.06.002 · Cited by 236
Zoroğlu, S. S., Armutçu, F., Özen, Ş., Gürel, A., Sivaslı, E., Yetkin, O., & Meram, İ. (2004) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-004-0456-7 · Cited by 235
Mitochondrial Medicine for Aging and Neurodegenerative Diseases
Reddy, P. H. (2008) · NeuroMolecular Medicine · doi:10.1007/s12017-008-8044-z · Cited by 230
Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System
Boekema, E. J., & Braun, H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r600031200 · Cited by 224
Casanova, M. F. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00100.x · Cited by 219
Palmieri, L., Papaleo, V., Porcelli, V., Scarcia, P., Gaita, L., Sacco, R., Hager, J., Rousseau, F., Curatolo, P., Manzi, B., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.63 · Cited by 210
Language and Other Regression: Assessment and Timing
Goldberg, W. A., Osann, K., Filipek, P. A., Laulhere, T. M., Jarvis, K. L., Modahl, C., Flodman, P. L., & Spence, M. A. (2003) · Journal of Autism and Developmental Disorders · doi:10.1023/b:jadd.0000005998.47370.ef · Cited by 206
Large Brains in Autism: The Challenge of Pervasive Abnormality
Herbert, M. R. (2005) · The Neuroscientist · doi:10.1177/0091270005278866 · Cited by 202
Relative Carnitine Deficiency in Autism
Filipek, P. A., Juranek, J. J., Nguyen, M. T., Cummings, C., & Gargus, J. J. (2004) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-004-5283-1 · Cited by 197
Minshew, N. J., Goldstein, G., Dombrowski, S. M., Panchalingam, K., & Pettegrew, J. W. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90017-8 · Cited by 186
Autism Associated With the Mitochondrial DNA G8363A Transfer RNALys Mutation
Graf, W. D., Marı́n-Garcı́a, J., Gao, H.-G., Pizzo, S., Naviaux, R. K., Markusic, D. M., Barshop, B. A., Courchesne, E., & Haas, R. (2000) · Journal of Child Neurology · doi:10.1177/088307380001500601 · Cited by 174
Hardan, A. Y., Minshew, N. J., Mallikarjuhn, M., & Keshavan, M. S. (2001) · Journal of Child Neurology · doi:10.1177/088307380101600607 · Cited by 170
Evidence of altered energy metabolism in autistic children
Chugani, D. C., Sundram, B. S., Behen, M. E., Lee, M.-L., & Moore, G. J. (1999) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00022-6 · Cited by 169
A simplified model for mitochondrial ATP production
Bertram, R., Pedersen, M. G., Luciani, D. S., & Sherman, A. (2006) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2006.07.019 · Cited by 168
Use of the Childhood Autism Rating Scale with Autistic Adolescents and Adults
Mesibov, G. B., Schopler, E., Schaffer, B., & MICHAL, N. (1989) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198907000-00012 · Cited by 164
Regression in Autism: Prevalence and Associated Factors in the CHARGE Study
Hansen, R. L., Ozonoff, S., Krakowiak, P., Angkustsiri, K., Jones, C., Deprey, L. J., Le, D.-N., Croen, L. A., & Hertz-Picciotto, I. (2008) · Ambulatory Pediatrics · doi:10.1016/j.ambp.2007.08.006 · Cited by 164
Autism: a mitochondrial disorder?
Lombard, J. (1998) · Medical Hypotheses · doi:10.1016/s0306-9877(98)90270-5 · Cited by 160
Parental report of the early development of children with regressive autism
Ozonoff, S. J., Williams, B. J., & Landa, R. J. (2005) · Autism · doi:10.1177/1362361305057880 · Cited by 159
Developmental Regression and Mitochondrial Dysfunction in a Child With Autism
Poling, J. S., Frye, R. E., Shoffner, J. M., & Zimmerman, A. W. (2006) · Journal of Child Neurology · doi:10.1177/08830738060210021401 · Cited by 155
Mitochondrial dysfunction in autistic patients with 15q inverted duplication
Filipek, P. A., Juranek, J. J., Smith, M., Mays, L. Z., Ramos, E. R., Bocian, M. E., Masser‐Frye, D., Laulhere, T. M., Modahl, C., Spence, M. A., et al. (2003) · Annals of Neurology · doi:10.1002/ana.10596 · Cited by 146
Filiano, J. J., Goldenthal, M. J., Rhodes, C. H., & Marı́n-Garcı́a, J. (2002) · Journal of Child Neurology · doi:10.1177/088307380201700607 · Cited by 143
Mitochondrial DNA abnormalities and autistic spectrum disorders
Pons, R. M., Andreu, A. L., Checcarelli, N., Vilà, M. R., Engelstad, K., Sue, C. M., Shungu, D. C., Haggerty, R., Vivo, D. C. D., & DiMauro, S. (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2003.10.023 · Cited by 138
Sugioka, K., Nakano, M., Totsune, H., Minakami, H., Tero‐Kubota, S., & Ikegami, Y. (1988) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(88)90014-x · Cited by 137
Navarro, A., Boveris, A., Bández, M. J., Sánchez-del-Pino, M. J., Gómez, C., Muntané, G., & Ferrer, I. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.03.007 · Cited by 136
McGinnis, W. R. (2005) · PubMed · Cited by 134
The Neuropathology of Autism: A Review
Pickett, J., & London, E. (2005) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000186921.42592.6c · Cited by 122
Increase in Cerebellar Neurotrophin-3 and Oxidative Stress Markers in Autism
Sajdel-Sulkowska, E. M., Xu, M., & Koibuchi, N. (2009) · The Cerebellum · doi:10.1007/s12311-009-0105-9 · Cited by 122
Correia, C., Coutinho, A. M., Diogo, L. M., Grazina, M. M., Marques, C., Miguel, T. S., Ataíde, A., Almeida, J., Borges, L., Oliveira, C. R., et al. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0138-6 · Cited by 114
Evidence for linkage to psychosis and cerebral asymmetry (relative hand skill) on the X chromosome
Laval, S. H., Dann, J. C., Butler, R. J., Loftus, J., Rue, J. E., Leask, S., Bass, N. J., Comazzi, M., Vita, A., Nanko, S., et al. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19980907)81:5 · Cited by 110
Neurometabolic disorders and dysfunction in autism spectrum disorders
Zecavati, N., & Spence, S. J. (2009) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-009-0021-x · Cited by 110
Fever Plus Mitochondrial Disease Could Be Risk Factors for Autistic Regression
Shoffner, J. M., Hyams, L., Langley, G. N., Cossette, S., Mylacraine, L., Dale, J., Ollis, L., Kuoch, S., Bennett, K., Aliberti, A., et al. (2009) · Journal of Child Neurology · doi:10.1177/0883073809342128 · Cited by 109
Purkinje cell vulnerability and autism: a possible etiological connection
Kern, J. K. (2003) · Brain and Development · doi:10.1016/s0387-7604(03)00056-1 · Cited by 108
Aliev, G., Palacios, H. H., Walrafen, B., Lipsitt, A. E., Obrenovich, M. E., & Morales, L. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.03.015 · Cited by 102
The neuropathology of autism: where do we stand?
Schmitz, C., & Rezaie, P. (2007) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2007.00872.x · Cited by 87
Targeting mitochondrial dysfunction in neurodegenerative disease: Part II
Burchell, V., Gandhi, S., Deas, E., Wood, N. W., Abramov, A. Y., & Plun‐Favreau, H. (2010) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728221003730434 · Cited by 83
Serum serotonin, lactate and pyruvate levels in infantile autistic children
László, A., Horváth, E., Eck, E., & Fekete, M. (1994) · Clinica Chimica Acta · doi:10.1016/0009-8981(94)90243-7 · Cited by 75
Ji, L., Chauhan, A., Brown, W. T., & Chauhan, V. (2009) · Life Sciences · doi:10.1016/j.lfs.2009.10.008 · Cited by 72
Self-citationA Microscopic Study of Language-Related Cortex in Autism
Lopez-Hurt, E., & Prieto, J. J. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.130.145 · Cited by 60
Mitochondrial Energy-Deficient Endophenotype in Autism
Gargus, J. J., & Imtiaz, F. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.198.207 · Cited by 53
Mitochondrial Enzymes in Schizophrenia
Bubber, P., Tang, J., Haroutunian, V. H., Xu, H., Davis, K. L., Blass, J. P., & Gibson, G. E. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:24:2:315 · Cited by 46
Scholes, T. A., & Hinkle, P. C. (1984) · Biochemistry · doi:10.1021/bi00309a035 · Cited by 46
Autistic Disorder in 2 Children With Mitochondrial Disorders
Tsao, C., & Mendell, J. R. (2007) · Journal of Child Neurology · doi:10.1177/0883073807306266 · Cited by 40
Xu, Y., Liu, P., & Li, Y. (2005) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20110 · Cited by 39
Patsoukis, N., & Georgiou, C. D. (2006) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2006.11.009 · Cited by 24
Mitochondrial dysfunction in autism spectrum disorders: a population-based study
Oliveira, G., Diogo, L. M., Grazina, M. M., Garcia, P., Psych, A. A., Marques, C., Miguel, T., Borges, L., Vicente, A. M., & Oliveira, C. R. (2007) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2005.tb01113.x · Cited by 21
Mitochondrial decay, a major cause of aging, can be delayed
Ames, B. N. (2004) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6202 · Cited by 20
Imaging of Autism: Lessons from the Past to Guide Studies in the Future
Goldberg, J., Szatmári, P., & Nahmias, C. (1999) · The Canadian Journal of Psychiatry · doi:10.1177/070674379904400806 · Cited by 20
Mitochondrial disease: Beyond etiology unknown
Read, C. Y., & Calnan, R. J. (2000) · Journal of Pediatric Nursing · doi:10.1053/jpdn.2000.8042 · Cited by 14
Rabbi‐Bortolini, E., Bernardino, A. L. F., Lopes, A. L., Ferri, A., Passos‐Bueno, M. R., & Zatz, M. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19980401)76:4 · Cited by 6
Type, Topography, and Sequelae of Neuropathological Changes Shaping Clinical Phenotype of Autism
Węgiel, J., Wısnıewskı, T., Chauhan, A., Chauhan, V. P. S., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Ma, S., Wierzba‐Bobrowicz, T., et al. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-c1 · Cited by 6
Self-citationEvidence for Oxidative Damage in the Autistic Brain
Evans, T. A., Perry, G. L., Smith, M. A., Salomon, R. G., McGinnis, W. R., Sajdel, E. M., & Zhu, X. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-c2 · Cited by 3
Research works printed but not linked: 1
- Muthaiyah B., 2009, Increased lipid peroxidation in cerebellum and temporal cortex of brain in autism, J. Neurochem., 108
Cited by
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Rossignol, D. A., & Frye, R. E. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00150 · Cited by 382
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Frustaci, A., Neri, M., Cesario, A., Adams, J. B., Domenici, E., Bernardina, B. D., & Bonassi, S. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.03.011 · Cited by 383
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Metadata
- Authors
- Chauhan, A., Gu, F., Essa, M. M., Wegiel, J., Kaur, K., Brown, W. T., & Chauhan, V.
- Affiliations
- New York State Office for People With Developmental Disabilities (US)
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 2011-02-24
- Volume
- 117
- Issue
- 2
- Pages
- 209-220
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- PMC
- PMC4839269
- OpenAlex
- W1577847097
- Cited by
- 243
- References
- 88
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 26 · 2023: 23 · 2022: 19 · 2021: 17 · 2020: 15 · 2019: 6 · 2018: 17 · 2017: 8 · 2016: 11 · 2015: 18 · 2014: 18 · 2013: 19 · 2012: 21
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neurochemistry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Defense
- Office for People With Developmental Disabilities
- National Institute on Aging (P30AG008051)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, cerebellum, frontal cortex, temporal cortex, oxidative stress, lipid hydroperoxides, brain energy metabolism, children versus adults
- MeSH terms
- Adolescent, Adult, Age Factors, Autistic Disorder, Brain, Child, Child, Preschool, Female, Humans, Lipid Peroxides, Male, Multienzyme Complexes, Postmortem Changes, Case-Control Studies, Reactive Oxygen Species, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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