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Cited by 51Substance Abuse Treatment and OutcomesEating Disorders and BehaviorsNeurotransmitter Receptor Influence on Behavior

Relationship between Substance Use and Body Mass Index in Young Males

Blüml, Victor, Kapusta, Nestor, Vyssoki, Benjamin, Kogoj, Dagmar, Walter, Henriette, Lesch, Otto M.·2012·The American Journal on Addictions
DOI 10.1111/j.1521-0391.2011.00192.x
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Abstract

Recent findings in basic scientific research, such as neurobiological and neuroimaging studies, have suggested common pathways for food and drug intake. It was hypothesized that both compete for the same brain reward sites, and that a higher body mass index (BMI) may be associated with lower substance use. The aim of this study was to investigate the relationship between BMI and substance use in a large sample of young male adults. The sample consisted of 1,902 18‐year‐old males from a province of Austria in a naturalistic cross‐sectional setting. Questionnaires were administered to assess alcohol abuse and dependence (CAGE) and nicotine dependence (Heavy Smoking Index). Urine samples were collected to assess the prevalence of recent illicit drug use. Associations between BMI and substance use were calculated by means of logistic regression analyses. An inverse relationship between BMI and recent illicit drug use was found. This relationship remained significant after adjusting for possible confounding factors such as level of education, nicotine dependence, breath carbon monoxide (CO) levels, and alcohol abuse and dependence. No significant association was found between BMI and nicotine and alcohol dependence. A higher BMI was associated with lower illicit drug use in our sample of young adult males. These results provide further evidence for the hypothesis that food and drugs may compete for the same brain reward sites. (Am J Addict 2011;21:72–77)

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  • In humans, BMI is inversely related to recent illicit drug use and obesity is associated with a lower risk for substance use disorders.

    “In humans, there have been reports of an inverse relationship between body mass index (BMI) and recent illicit drug use (35) and of an association between obesity and a lower risk for substance use disorders (36).”

    From Obesity and addiction: Neurobiological overlaps (2013) · cites this paper as [35]

  • Human studies found an inverse relationship between BMI and illicit drug use and lower risk for substance use disorders in obese individuals, including lower rates of nicotine and marijuana abuse.

    “Similarly, human studies found an inverse relationship between BMI and illicit drug use (21) and a lower risk for substance use disorders in obese individuals (22), including lower rates of nicotine (23) and marijuana (24) abuse.”

    From The Addictive Dimensionality of Obesity (2013) · cites this paper as [21]

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Authors
Blüml, V., Kapusta, N., Vyssoki, B., Kogoj, D., Walter, H., & Lesch, O. M.
Affiliations
Medical University of Vienna (AT)
ORCID
Venue
The American Journal on Addictions
Publisher
Wiley
Published
2011-12-15
Volume
21
Issue
1
Pages
72-77
ISSN
  • 1055-0496 (ISSN-L)
  • 1521-0391
DOI
10.1111/j.1521-0391.2011.00192.x
OpenAlex
W2150926376
Cited by
51
References
54
Citations by year
2025: 1 · 2024: 2 · 2022: 3 · 2021: 1 · 2020: 6 · 2018: 4 · 2017: 1 · 2016: 4 · 2015: 6 · 2014: 7 · 2013: 11 · 2012: 4
FWCI
5.52
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • American Journal on Addictions (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
body mass index, substance use, illicit drug use, alcoholism, nicotine dependence, young men, brain reward system
MeSH terms
Adolescent, Alcoholism, Austria, Humans, Male, Obesity, Surveys and Questionnaires, Smoking, Statistics as Topic, Tobacco Use Disorder, Substance Abuse Detection, Body Mass Index, Prevalence, Substance-Related Disorders, Diagnostic and Statistical Manual of Mental Disorders

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