How can drug addiction help us understand obesity?
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Humans with obesity and those with substance use disorders show overlapping neuroimaging characteristics, including reductions in DA-D2 receptors.
“Soon after, investigators documented overlapping neuroimaging characteristics in humans with obesity and those with substance use disorders (SUDs), showing reductions in DA-D2 receptors [4].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [4]
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- Authors
- Volkow, N. D., & Wise, R. A.
- Affiliations
- National Institutes of Health (US)
- Venue
- Nature Neuroscience
- Published
- 2005-04-26
- Volume
- 8
- Issue
- 5
- Pages
- 555-560
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2142013939
- Cited by
- 1,089
- References
- 61
- Citations by year
- 2026: 13 · 2025: 26 · 2024: 19 · 2023: 33 · 2022: 35 · 2021: 41 · 2020: 83 · 2019: 37 · 2018: 50 · 2017: 43 · 2016: 56 · 2015: 65 · 2014: 76 · 2013: 66 · 2012: 81
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- drug addiction, obesity, food reward, reward systems, neural circuits, food-motivated behavior, appetitive behavior
- MeSH terms
- Adaptation, Physiological, Animals, Appetite Regulation, Brain, Dopamine, Humans, Neural Pathways, Obesity, Reinforcement, Psychology, Behavior, Addictive, Substance-Related Disorders
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