Cited by 841Cardiac Health and Mental HealthCancer survivorship and careMental Health Treatment and Access

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Prevalence of depression in survivors of acute myocardial infarction: Review of the evidence

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Thombs, Brett D., Bass, Eric B., Ford, Daniel E., Stewart, Kerry J., Tsilidis, Konstantinos K., Patel, Udita, Fauerbach, James A., Bush, David E., Ziegelstein, Roy C.·2006·Journal of General Internal Medicine

DOI 10.1111/j.1525-1497.2005.00269.xPMC PMC1484630

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Abstract

Objectives To assess the prevalence and persistence of depression in patients with acute myocardial infarction (AMI) and the relationship between assessment modality and prevalence.Data sources MEDLINE, Cochrane, CINAHL, PsycINFO, and EMBASE.Review methods A comprehensive search was conducted in March 2004 to identify original research studies published since 1980 that used a standardized interview or validated questionnaire to assess depression. The search was augmented by hand searching of selected journals from October 2003 through April 2004 and references of identified articles and reviews. Studies were excluded if only an abstract was provided, if not in English, or if depression was not measured by a validated method.Results Major depression was identified in 19.8% (95% confidence interval [CI] 19.1% to 20.6%) of patients using structured interviews (N=10,785, 8 studies). The prevalence of significant depressive symptoms based on a Beck Depression Inventory score > or =10 was 31.1% (CI 29.2% to 33.0%; N=2,273, 6 studies), using a Hospital Anxiety and Depression Scale (HADS) score > or =8%, 15.5% (CI 13.2% to 18.0%; N=863, 4 studies), and with a HADS score > or =11%, 7.3% (CI 5.5% to 9.3%; N=830, 4 studies). Although a significant proportion of patients continued to be depressed in the year after discharge, the limited number of studies and variable follow-up times precluded specification of prevalence rates at given time points.Conclusions Depression is common and persistent in AMI survivors. Prevalence varies depending on assessment method, likely reflecting treatment of somatic symptoms.

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Authors: Thombs, B. D., Bass, E. B., Ford, D. E., Stewart, K. J., Tsilidis, K. K., Patel, U., Fauerbach, J. A., Bush, D. E., & Ziegelstein, R. C.
Affiliations: Johns Hopkins University (US)
Corresponding author: Ziegelstein, Roy C.
ORCID: Thombs, Brett D.
Bass, Eric B.
Ford, Daniel E.
Stewart, Kerry J.
Tsilidis, Konstantinos K.
Patel, Udita
Ziegelstein, Roy C.
Venue: Journal of General Internal Medicine
Publisher: Springer Science and Business Media LLC
Published: 2006-01
Volume: 21
Issue: 1
Pages: 30-38
ISSN: 0884-8734 (ISSN-L)
1525-1497
DOI: 10.1111/j.1525-1497.2005.00269.x
PMC: PMC1484630
OpenAlex: W1481220499
Cited by: 841
References: 81
Citations by year: 2026: 22 · 2025: 28 · 2024: 26 · 2023: 53 · 2022: 47 · 2021: 45 · 2020: 49 · 2019: 50 · 2018: 62 · 2017: 55 · 2016: 64 · 2015: 55 · 2014: 46 · 2013: 47 · 2012: 47
FWCI: 2.23
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of General Internal Medicine (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
eScholarship@McGill (McGill) (submittedVersion)
Funders: U.S. Public Health Service (290-02-0018)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: depression, acute myocardial infarction, depression prevalence, depression persistence, depressive symptoms, Beck Depression Inventory, Hospital Anxiety and Depression Scale, somatic symptoms
MeSH terms: Depressive Disorder, Hospitalization, Humans, Myocardial Infarction, Prevalence

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Prevalence of depression in survivors of acute myocardial infarction: Review of the evidence

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