Cited by 147Dementia and Cognitive Impairment ResearchPalliative Care and End-of-Life IssuesAging, Health, and Disability

Prognostic Factors in Very Old Demented Adults: A Seven‐Year Follow‐Up From a Population‐Based Survey in Stockholm

Agüero‐Torres, Hedda, Fratiglioni, Laura, Guo, Zhenchao, Viitanen, Matti, Winblad, Bengt·1998·Journal of the American Geriatrics Society

Abstract

Objective To detect prognostic factors in very old demented subjects with Alzheimer's disease (AD), vascular dementia (VaD), and other types of dementia (OD). Design Follow-up clinical examinations of dementia patients from a population-based study after 3- and 7-year intervals. Setting and participants In an established population aged 75 years and older in Stockholm, Sweden, there were 133 cases of AD, 52 of VaD, and 38 of OD. Main outcome measures Predictors of survival at 3- and 7-year follow-up examinations were evaluated by Cox proportional hazard models. Progression was measured as the annual rate of change in Mini-Mental State Examination (MMSE) scores. Linear models were used to evaluate predictors of progression. Results Older age, male gender, low education, comorbidity, and functional disability predicted shorter 7-year survival in the 223 prevalent dementia cases. Other factors, including type of dementia, dementia severity, and duration of the disease were not significant. The average rate of cognitive decline in the 81 mild to moderate demented subjects who survived 3 years was 2.4 MMSE points per year. Type of dementia (AD vs OD), higher baseline cognitive function, and greater functional disability predicted faster decline. Despite similar survival probability, predictors of death varied as a function of dementia type: Older age (for AD and VaD), comorbidity (for AD and OD), and functional dependency (for VaD). In AD, prognostic factors were similar to those…

Integrity signals

Registry

Crossref · 10.1111/j.1532-5415.1998.tb02464.x

Cites

54 of 54 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Agüero‐Torres, H., Fratiglioni, L., Guo, Z., Viitanen, M., & Winblad, B.
Affiliations
Karolinska Institutet (SE)
Corresponding author
Agüero‐Torres, Hedda
Venue
Journal of the American Geriatrics Society
Publisher
Wiley
Published
1998-04
Volume
46
Issue
4
Pages
444-452
ISSN
  • 0002-8614 (ISSN-L)
  • 1532-5415
OpenAlex
W2067887764
Cited by
147
References
54
Citations by year
2026: 1 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 7 · 2021: 2 · 2020: 5 · 2019: 1 · 2018: 4 · 2017: 5 · 2016: 9 · 2015: 3 · 2014: 5 · 2013: 7 · 2012: 2
FWCI
5.74
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of the American Geriatrics Society (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords
dementia prognosis, Alzheimer's disease, vascular dementia, survival, cognitive decline, functional disability, comorbidities, educational attainment, sex differences, oldest old, Mini-Mental State Examination
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease, Dementia, Female, Follow-Up Studies, Health Surveys, Humans, Male, Mental Status Schedule, Prognosis, Psychometrics, Sweden, Urban Population, Dementia, Vascular, Geriatric Assessment, Survival Analysis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review