Cited by 1,027Frailty in Older AdultsStatistical Methods in Clinical TrialsEthics in Clinical Research

The DOI matches its Crossref record; 76 of the 79 references it cites were found in a registry or an index.

Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

Ferrucci, Luigi, Guralnik, Jack M., Studenski, Stephanie, Fried, Linda P., Cutler, Gordon B., Walston, Jeremy D., The Interventions on Frailty Working Group·2004·Journal of the American Geriatrics Society

DOI 10.1111/j.1532-5415.2004.52174.x

Open this paper in CoChat — free account

Abstract

The discovery of effective interventions to prevent or delay disability in older persons is a public health priority. Most likely to benefit from such interventions are frail individuals who are not yet disabled and those with early disability who are at high risk of progression. In spite of this frail older persons have often been excluded from research on the assumption that they would not tolerate testing or benefit from treatment. The Interventions on Frailty Working Group developed recommendations to screen, recruit, evaluate, and retain frail older persons in clinical trials. Specific recommendations are: Eligibility screening should include a multistage process, to quickly exclude those who are too well and those who are too sick. Inclusion criteria should target those most likely to benefit, be meaningful to clinicians, and reflect advancements in the frailty research area. Disability outcome measures should include self‐reported, objective, and proxy measures. Strategies to improve retention and compliance and to monitor their effectiveness should be an integral part of the study design. Estimation of cost and sample size should contemplate high dropout rates and interference bycompeting outcomes. Additional research is needed to refine criteria for screening frail older persons, identify objective measures of disability that are reliable and valid in frail older persons, and improve the informed consent process for high‐risk participants, recognizing that research in this subgroup is essential to improving their health outcomes.

Integrity signals

Registry

Crossref · 10.1111/j.1532-5415.2004.52174.x

Cites

76 of 76 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
Self-citation
A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission
Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.2.m85 · Cited by 9,792
Self-citation
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials
Moher, D., Schulz, K. F., & Altman, D. G. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04337-3 · Cited by 5,373
Validating the SF-36 health survey questionnaire: new outcome measure for primary care.
Brazier, J. E., Harper, R., Jones, N. M., O’Cathain, A., Thomas, K. J., Usherwood, T. P., & Westlake, L. (1992) · BMJ · doi:10.1136/bmj.305.6846.160 · Cited by 4,660
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease
Moms, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., van Belle, G., Fillenbaum, G., Mellits, E. D., & Clark, C. (1989) · Neurology · doi:10.1212/wnl.39.9.1159 · Cited by 4,130
Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability
Guralnik, J. M., Ferrucci, L., Simonsick, E. M., Salive, M. E., & Wallace, R. B. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503023320902 · Cited by 4,083
Self-citation
The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration
Altman, D. G., Schulz, K. F., Moher, D., Egger, M., Davidoff, F., Elbourne, D., Gøtzsche, P. C., Lang, T., & for the CONSORT Group (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-8-200104170-00012 · Cited by 3,835
Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery
Guralnik, J. M., Ferrucci, L., Pieper, C. F., Leveille, S. G., Markides, K. S., Ostir, G. V., Studenski, S., Berkman, L. F., & Wallace, R. B. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.4.m221 · Cited by 2,898
Self-citation
The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials
Moher, D., Schulz, K. F., & Altman, D. G. (2001) · BMC Medical Research Methodology · doi:10.1186/1471-2288-1-2 · Cited by 2,755
A Multifactorial Intervention to Reduce the Risk of Falling among Elderly People Living in the Community
Tinetti, M. E., Baker, D. I., McAvay, G., Claus, E. B., Garrett, P., Gottschalk, M., Koch, M. L., Trainor, K. M., & Horwitz, R. I. (1994) · New England Journal of Medicine · doi:10.1056/nejm199409293311301 · Cited by 2,160

Show all 79 references

Research works printed but not linked: 2

10.1001/jama.1989.03420180087036 · DOI
Vellas B, 2000, [Falls, frailty and osteoporosis in the elderly, A public health problem], 21, 608

Sorted by citations

Items 901–999 of 999

Physical therapy treatment on frailty syndrome: systematic review Atuação da fisioterapia na síndrome de fragilidade: revisão sistemática
Arantes, P. M. M., Alencar, M. A., Dias, R. C., Marcos, J., Dias, D. P. M., & Pereira, L. S. M. (2009)
exercise-induced weight loss capacity decrease with caloric restriction but not with Lower extremity muscle size and strength and aerobic
Schechtman, K. B., Klein, S., Ehsani, A. A., Weiss, P., Racette, S. B., Villareal, D. T., Fontana, L., Lavie, J.-L., Church, T. S., Sénéchal, M., et al. (2015)
Consideraciones críticas acerca del programa tradicional de la asignatura Medicina Interna. Critical considerations on the traditional syllabus of the subject Internal Medicine.
Pedagógica, I., Julio, Á., & Cabrera, R. (2009) · Dialnet (Universidad de la Rioja)
Fragilité et maladie d’Alzheimer
Houles, M., & van Kan, G. A. (2013) · Springer eBooks · doi:10.1007/978-2-8178-0443-9_19
Prevalência e fatores associados às doenças reumáticas e aos sintomas articulares crônicos em idosos
Falsarella, G. R. (2010) · doi:10.47749/t/unicamp.2010.775516
Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease
Gauthier, S. G. (2007) · Springer eBooks · doi:10.1007/978-0-387-71522-3_2
Relação entre atividade física, capacidade funciona,l velocidade da marcha, sintomas de insônia, cochilo diurno, sintomas depressivos e ocorrência de quedas em idosos residentes na comunidade
Pereira, A. A. (2011) · doi:10.47749/t/unicamp.2011.804104
Management of breast cancer in older adults
Shayne, M., & Kimmick, G. G. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511763182.007
Epidemiologia da incapacidade funcional em idosos na comunidade: Inquérito de Saúde de Belo Horizonte e tradução e confiabilidade do instrumento de avaliação funcional SMAF no Projeto Bambuí.
da Saúde, M., & Giacomin, K. C. (2008) · Americanae (AECID Library)
Stimulation of different foot structures and functions : effects on physical performance in older adults
Hartmann, A. (2009) · doi:10.26481/dis.20091106ah
Sintomas de insônia e sono diurno associados à ocorrência de hipertensão e diabetes mellitus em idosos
Freitas, D. C. D. C. V. (2013) · doi:10.47749/t/unicamp.2013.901796
Relações entre exercícios físicos, força muscular e atividades de vida diária em mulheres idosas recrutadas na comunidade
Ribeiro, L. H. M. (2011) · doi:10.47749/t/unicamp.2011.841106
The Urgent Need for More Clinical Pharmacology Studies in Older Patients to Improve Drug Therapy in a Rapidly Growing at Risk Cohort
SITAR, D. S. (2012) · Clinical and Experimental Pharmacology · doi:10.4172/2161-1459.1000e115
“In addition, the increased prevalence of frailty with increasing age is almost certain to confound analysis and interpretation of data from such studies [11,12].”
Background
RELACIÓN ENTRE PARÁMETROS FUNCIONALES RESPIRATORIOS Y CLÍNICOS EN UNA COHORTE PROSPECTIVA DE ANCIANOS FRÁGILES COMUNITARIOS
Martínez‐Arnau, F. M., Pérez-Ros, M. P., Piera, C. C., & Tarazona‐Santabalbina, F. J. (2015) · Dialnet (Universidad de la Rioja)
a síndromE dE fragilidadE no idoso
Lourenço, R. A. (2008)
Aspects of treatment and care of nursing home residents. Challenges and possibilities.
Bolmsjö, B. B. (2016) · Lund University Publications (Lund University)
Análise da bateria de testes "Short Physical Performance Battery" de acordo com a classificação de fragilidade em idosos da comunidade - Estudo FIBRA
de Mello, M. J. C. (2015) · doi:10.47749/t/unicamp.2015.957187
Consensus Statement on Cardiac Diseases in Elderly Patients / Abbridged Version
Lax, J. A. (2016) · Dialnet (Universidad de la Rioja) · doi:10.7775/rac.84.3.8501
Delirium in frail surgical oncology patients
Hempenius, L. (2014) · University of Groningen research database (University of Groningen / Centre for Information Technology)
Mastering the design of clinical trials for older persons
Ferrucci, L., & Studenski, S. A. (2015) · doi:10.1002/9781118323434.ch4
Self-citation
Burden of disease, symptoms and self-rated health among frail elderly people
Ternrud, B. (2016) · Gothenburg University Publications Electronic Archive (Gothenburg University)
The Perceptions and Experiences of Mobility Scooters by Older Adults Experiencing a Decline in Mobility
Thoreau, R. (2016) · UCL Discovery (University College London)
Evaluation of the Effect of Stay On Your Feet, a Community-Delivered Falls Prevention Program for Older Adults, on Falls-Related Self-Efficacy and Balance
Duncan, C. L. (2007) · QSpace (Queen's University Library)
Research in Special Populations
Studenski, S. A., & Ferrucci, L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802101-9.00029-6
Self-citation
Queda e sua relação com fatores sociodemográficos e de saúde em idosos de uma comunidade brasileira: estudo de seguimento
Fhon, J. R. S. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.22.2016.tde-30092016-164859
Analysis of the relationship between the syndrome of frailty and cognitive deficit in older adults with independent living
da Cunha, G. L., Cabral, S. M., & dos Santos, G. A. (2017) · Análise Psicológica · doi:10.14417/ap.1145
“According recommendations of Ferrucci et al. (2004), were considered ineligible for research through observation: (a) seniors with severe cognitive deficit suggestive of dementia, evidenced by memory problems, attention, spatial and temporal orientation, and communication; (b) those who were using…”
Method
Metodologia e perfil sociodemográfico, cognitivo e de fragilidade de idosos comunitários de sete cidades brasileiras: Estudo FIBRA Methodology and social, demographic, cognitive, and frailty profiles of community-dwelling elderly from seven Brazilian cities: the FIBRA Study Metodología y perfil sociodemográfico, cognitivo y de fragilidad de ancianos en comunidades desfavorecidas de siete ciudades brasileñas:
Neri, A. L., Yassuda, M. S., de Araújo, L. F., Eulálio, M. D. C., Cabral, B. E., de Siqueira, M. E. C., & de Arruda, J. G. (2013)
A identificação da síndrome da fragilidade no comprometimento cognitivo leve em idosos
Cezar, N. O. D. C. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2017.tde-16052017-171439
[Relationship between streptomycin susceptibility and rpsL mutations of Mycobacterium tuberculosis strains].
Fukuda, M., Koga, H., Ohno, H., Ogawa, K., Yang, B., Miyamoto, J., Tomono, K., & KOHNO, S. (1997) · PubMed
Síndrome de fragilidad en pacientes con fractura vertebral. Asociación con polimorfismos de genes de autofagia
Carranco-Medina, T. E. (2017) · Gredos (University of Salamanca) · doi:10.14201/gredos.135753
Associação entre quedas e fragilidade em idosos do município de São Paulo, segundo o Estudo SABE
Duarte, G. P. (2016) · doi:10.11606/t.17.2016.tde-29082016-104634
RETRACTED ARTICLE: Management of Frailty: Screening and Interventions
Fougère, B. (2018) · The journal of nutrition health & aging · doi:10.1007/s12603-018-1009-5
Retracted
Efectos del kinesiotape en el equilibrio y la marcha en mayores inactivos
Ortíz‐Rubio, A., Martos, I. C., Casilda-López, J., Ariza-Mateos, M. J., Romero-Fernández, R., & Valenza, M. C. (2018) · Fisioterapia · doi:10.1016/j.ft.2018.01.003
Análise das relações municipais de medicamentos essenciais de municípios do estado de São Paulo e aplicação dos critérios de beers
Chiaroti, R. (2018) · doi:10.11606/d.17.2018.tde-26042018-112244
Pelvic floor physical therapy in the elderly
Wagg, A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-7020-4443-4.00011-x
Influência da Ginástica na Aptidão Física Funcional de Mulheres
Petreça, D. R., Hauser, E., Mazo, G. Z., & Benedetti, T. R. B. (2015) · Revista Brasileira de Ciência e Movimento · doi:10.18511/0103-1716/rbcm.v23n2p137-147
Frailty in Aortic Surgery
Mack, M. J. (2019) · Springer eBooks · doi:10.1007/978-3-7091-4874-7_15
Adjuvant Systemic Therapy
Battisti, N. M. L., & Ring, A. E. (2019) · Springer eBooks · doi:10.1007/978-3-030-11875-4_10
Epidemiologic evidence for physical activity as a preventative factor for metabolic syndrome and frailty: the Health ABC Study
Peterson, M. J. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/wzwf-h359
EFEITO DE UM PROGRAMA DE EXERCÌCIOS NAS MODALIDADES PRESENCIAIS E DOMICILAR NA FUNCIONALIDADE DE IDOSAS PRÉ-FRÁGEIS
Costa, S., de Mattos, F., Garcia, R., & Bento, P. (2019) · Estudos Interdisciplinares sobre o Envelhecimento · doi:10.22456/2316-2171.97738
Home-Based Rehabilitation and its Impact on Hospital Utilization
Knott, T. C. (2013) · QSpace (Queen's University Library)
Sarcopenia
Rolland, Y., & Vellas, B. J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6231-8.10073-x
Comprehending the Comprehensive Geriatric Assessment. Feasibility, outcomes and experiences of frail older people
Westgård, T. (2020) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Does Assessment of Frailty and Sarcopenia in Lung Resection Candidates Affect Patient Selection?
Huisingh-Scheetz, M. J., & Martinchek, M. (2020) · Difficult decisions in surgery: an evidence-based approach · doi:10.1007/978-3-030-47404-1_9
Frailty in Acute Kidney Injury Critical Care Patient
González, M. E., Fuentes, N. A., Franco, C. L., Lombardi, M., Musso, C. G., & Esperatti, E. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-53529-2_10
Peer Review #1 of "Using the FRAIL scale to compare pre-existing demographic lifestyle and medical risk factors between non-frail, pre-frail and frail older adults accessing primary health care: a cross-sectional study (v0.1)"
(2020) · PeerJ · doi:10.7287/peerj.10380v0.1/reviews/1
Correlates of improvement of care need level in disabled older adults: Two-year follow-up study in 11,585 older peoplePreprint
Hayashi, Y., Hato, S., & Shimada, H. (2019) · Research Square · doi:10.21203/rs.2.14919/v1
Fragilidade, sarcopenia e mobilidade nos espaços de vida de idosos
de Lima, M. D. C. C. (2020) · doi:10.47749/t/unicamp.2020.1157188
Fragilidade, desempenho cognitivo e sintomas depressivos de idosos ribeirinhos da Amazônia
do Nascimento, R. G., Pinto, D. D. S., Magalhães, C. M. C., Cardoso, R. D. O., Cunha, K. D. C., Piedade, A. B. D. S., & Puga, G. R. (2021) · Estudos Interdisciplinares em Psicologia · doi:10.5433/2236-6407.2021v12n2p23
Évolution des profils d'état de santé et utilisation des services sociosanitaires chez les personnes âgées
Lafortune, L. (2009) · doi:10.71781/1582
Definições de fragilidade em idosos
Teixeira, I. N. D. O. (2006) · doi:10.47749/t/unicamp.2006.385981
Frailty Screening
Hamaker, M. E. (2021) · Springer eBooks · doi:10.1007/978-3-030-22009-9_764
Comparação de duas definições de fragilidade na avaliação de risco para morte em idosos participantes do estudo fibra Campinas
Pereira, A. A. (2016) · doi:10.47749/t/unicamp.2016.977088
Frailty in later life
der Elst, M. V. (2022) · doi:10.26481/dis.20220202me
A conspectus on physical condition and quality of life
Kumar, S. N., & Geetha, P. V. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns3.6827
Inflammatory potential of diet and aging
Orchard, T., Lohman, M. C., & Kopec, R. E. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822130-3.00001-6
Desempenho cognitivo e funcionalidade em idosos residentes na comunidade
de Menezes, V. (2013) · doi:10.47749/t/unicamp.2013.912006
Associação entre os problemas da deglutição com as medidas de força muscular e velocidade de marcha em idosos octogenários
Ortega, N. C. (2020) · doi:10.47749/t/unicamp.2020.1149085
Frail Elderly
Satariano, W. A., & Maus, M. (2013) · doi:10.1093/obo/9780199756797-0078
F
(2007) · Elsevier eBooks · doi:10.1016/b978-032304195-9.50008-0
Indicadores de fragilidade e tempo despendido em atividades em idosos
Marincolo, J. C. S. (2011) · doi:10.47749/t/unicamp.2011.786569
Desempenho no MEEM em idosos frágeis, pré-frágeis e não frágeis residentes na comunidade
Macuco, C. R. M. (2011) · doi:10.47749/t/unicamp.2011.836840
Exercise
Hall, W. J. (2007) · Elsevier eBooks · doi:10.1016/b978-1-4160-2261-9.50017-3
Peer Review #2 of "Using the FRAIL scale to compare pre-existing demographic lifestyle and medical risk factors between non-frail, pre-frail and frail older adults accessing primary health care: a cross-sectional study (v0.1)"
(2020) · PeerJ · doi:10.7287/peerj.10380v0.1/reviews/2
Velocidade da marcha, força de preensão e saúde percebida em idosos
Bez, J. P. D. O. (2011) · doi:10.47749/t/unicamp.2011.805302
Frailty Screening
Hamaker, M. E. (2020) · Springer eBooks · doi:10.1007/978-3-319-69892-2_764-1
Como entender os parametros eritroides no contexto do fenotipo da fragilidade
Silva, J. C. E. (2013) · doi:10.47749/t/unicamp.2013.914606
Associação entre atividade física, aptidão física e mortalidade em idosos da comunidade
de Araújo, C. M. N. F. (2017) · doi:10.47749/t/unicamp.2017.989605
Estado nutricional, adiposidade abdominal e síndrome da fragilidade em idosos da comunidade
Moretto, M. C. (2012) · doi:10.47749/t/unicamp.2012.894541 · Cited by 1
General principles of recovery and rehabilitation
Wyller, T. B., & Bautz‐Holter, E. (2017) · doi:10.1093/med/9780198701590.003.0027
Peer Review #2 of "Using the FRAIL scale to compare pre-existing demographic lifestyle and medical risk factors between non-frail, pre-frail and frail older adults accessing primary health care: a cross-sectional study (v0.2)"
(2020) · PeerJ · doi:10.7287/peerj.10380v0.2/reviews/2
Preventing falls in older people
(2014) · Pharmaceutical journal/The pharmaceutical journal · doi:10.1211/pj.2014.20066844
Koruyucu Sağlıkta Fiziksel Aktivite Danışmanlığı: Derleme
Tokgoz, G. (2022) · Balıkesır Health Sciences Journal · doi:10.53424/balikesirsbd.1089892
Preventing falls in older people
(2015) · Nursing Standard · doi:10.7748/ns.29.34.19.s25
남해군에서의 소지역 건강 격차 해소 사업
강, 양., 박, 수., 서, 애., 김, 미., 김, 보., & 박, 기. (2022) · Public Health Weekly Report · doi:10.56786/phwr.2022.15.44.2765
Analysis of Frailty Factors in People over 55 Years Old in Inner Mongolia Autonomous Region
闫, 红. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.131016
Stratified assessment for geriatric mental health using probabilistic graphical model: a cross-sectional observational study in IndiaPreprint
Jha, I. P., Mishra, S. V., Pandey, N., & Kumar, V. (2023) · medRxiv · doi:10.1101/2023.03.26.23287749
Pre-morbid frailty is associated with poor outcome after thrombolysis in older patients with ST-elevation Myocardial Infarction
Aggarwal, A., Deorari, V., Raizada, A., Sharma, R., Avasthi, R., & Goel, A. (2023) · GSC Biological and Pharmaceutical Sciences · doi:10.30574/gscbps.2023.24.1.0282
Stratified assessment for geriatric mental health using probabilistic graphical model: a cross-sectional observational study in India (Preprint)Preprint
Jha, I. P., Mishra, S. V., Pandey, N., Kumar, A., & Kumar, V. (2023) · doi:10.2196/preprints.25096
Nutrição no Século XXI
Treptow, T. C., Brasil, C. C. B., & Copetti, C. (2023) · Editora Científica Digital eBooks · doi:10.37885/978-65-5360-407-0
DESEMPENHO FUNCIONAL E COMPOSIÇÃO CORPORAL EM IDOSOS INSTITUCIONALIZADOS: UMA ANÁLISE LONGITUDINAL
Mendes, E., Preto, L. S. R., & Novo, A. (2023) · Editora Científica Digital eBooks · doi:10.37885/230713822
ปจจยคดสรรทสมพนธกบภาวะเปราะบางของผสงอายทอยในบานพกคนชราของภาครฐ
เนตรจันทร์, ป. (2017) · doi:10.58837/chula.the.2017.1096
ผลของโปรแกรมการสรางพลงอำนาจและการออกกำลงกายแบบตานแรงตอภาวะเปราะบางของผสงอายในชมชน
นาคขํา, ก. (2017) · doi:10.58837/chula.the.2017.1060
Maßnahmen zur Gesundheitsförderung von Pflegebedürftigen nach dem Leitfaden Prävention: Bewegung und körperliche Aktivität
Voelcker‐Rehage, C., Janssen, T. I., Cordes, T., & Wollesen, B. (2023) · Springer eBooks · doi:10.1007/978-3-662-67020-0_13 · Cited by 1
Situação de diagnóstico e tratamento da hipertensão arterial em idosos brasileiros e inter-relações de variáveis pressóricas com cognição e fragilidade
Santimaria, M. R. (2019) · doi:10.47749/t/unicamp.2019.1165446
Relações entre aspectos psicossociais e desempenho cognitivo em uma coorte de idosos residentes na comunidade: dados da segunda onda do Estudo FIBRA
Oliveira, W. L. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.100.2023.tde-24102023-212532
Frailty, functional capacity, institutionalization, and quality of life
Smithard, D. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91686-8.00047-1
Benefícios das práticas corporais de combate no idoso: revisão sistemática
de Mendonça, D. L. C. (2024) · doi:10.11606/t.5.2024.tde-23042024-165246
Frailty Measure Development, Selection, and Implications
Bandeen‐Roche, K. (2024) · Springer eBooks · doi:10.1007/978-3-031-57361-3_17
Exploring bite force as an indicator of frailty phenotype: a pilot studyPreprint
Ferreira, L. M. A., Scoz, R. D., da Silva, J. R. T., da Silva, M. L., Brito, J., Amorim, C. F., de Júdice, A. F. T., Mendes, J. J., Machado, V., & Botelho, J. (2024) · Research Square · doi:10.21203/rs.3.rs-4607026/v1
The availability of care among frail older adults: impacts on care management in a crisis context — the Fibra Study
Torres, J. L., & Lustosa, L. P. (2024) · Cadernos Saúde Coletiva · doi:10.1590/1414-462x202432010201
“Participants were excluded if they had any stroke, had Parkinson’s disease, were using a wheelchair, and were bedridden 24 .”
Calculation of the Frailty Index and Precautions for Elderly Patients Undergoing Gastrointestinal Cancer Surgery
Şahin, E., Şahin, K., Ulutaş, M. E., Turan, Y., GÜLER, S. A., Şimşek, T., & Cantürk, N. Z. (2025) · Cureus · doi:10.7759/cureus.78097
“Some researchers define frailty in terms of physical parameters such as endurance, muscle strength, balance, weight loss, mobility, and physical activity [14,19,20], while other researchers perceive frailty in a larger sense that includes psychosocial factors and cognitive impairment [21-23].”
Reliability and validity of a full-body function Get-Up test in older adults
Meier, N. F., Klinedinst, B. S., & Lee, D.-C. (2025) · GeroScience · doi:10.1007/s11357-025-01643-4
“…and lower quality of life associated with increased morbidity, mobility disability, and mortality in older adults [3] underscore the urgent need to focus on identifying deficiencies in physical function and strength [4], given their established relationship with these adverse outcomes [5].”
The mediating and joint effects of depression in the association between cardiovascular health and frailty in middle-aged and elderly people: evidence from NHANES
Ma, Q., Zou, Z., Liu, Y., & Zhang, L. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1578743
Impacto da renda e escolaridade em indicadores de saúde e funcionalidade em idosos viventes na comunidade
de Bortolli, T. T., Marques, N. R., Prata, G. M., & Carnaz, L. (2025) · Caderno Pedagógico · doi:10.54033/cadpedv22n6-185
Patient Participation for Frail Older Persons and Their Next of Kin in Hospital Care—A Scoping Review
Bengtsson, P., Larsson, M., & Eklund, A. J. (2025) · International Journal of Older People Nursing · doi:10.1111/opn.70031
CR in HF: impact of frailty and mobility on proportion of inpatients eligible for CR referral at the point of discharge
Waterhouse, H., Squire, I., & Singh, S. (2025) · British Journal of Cardiology · doi:10.5837/bjc.2025.025
Frailty in Alzheimer's disease: A bibliometric analysis of research hotspots, emerging trends, and knowledge structure
Shi, L., Tian, X., Lu, X., Yih, B., & Chen, J. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251362665
“36 The ten most cited references 40 – 49 (Supplemental Table 1) explore the multifaceted relationship between AD and frailty across protein misfolding, in ﬂ ammation, aging mechanisms, cognitive function, and neurodegenerative vulnerability.”
Additional file 1 of Effect of nutritional and physical exercise intervention on hospital readmission for patients aged 65 or older: a systematic review and meta-analysis of randomized controlled trials
Lærum‐Onsager, E., Molin, M., Olsen, C. F., Bye, A., Debesay, J., Hestevik, C. H., Bjerk, M., & Pripp, A. H. (2021) · Figshare · doi:10.6084/m9.figshare.14570006

Authors: Ferrucci, L., Guralnik, J. M., Studenski, S., Fried, L. P., Cutler, G. B., Walston, J. D., & The Interventions on Frailty Working Group
Affiliations: National Institutes of Health (US)
ORCID: Ferrucci, Luigi
Guralnik, Jack M.
Studenski, Stephanie
Fried, Linda P.
Cutler, Gordon B.
Walston, Jeremy D.
Venue: Journal of the American Geriatrics Society
Publisher: Wiley
Published: 2004-03-30
Volume: 52
Issue: 4
Pages: 625-634
ISSN: 0002-8614 (ISSN-L)
1532-5415
DOI: 10.1111/j.1532-5415.2004.52174.x
OpenAlex: W1562992882
Cited by: 1,027
References: 79
Citations by year: 2026: 19 · 2025: 31 · 2024: 24 · 2023: 22 · 2022: 22 · 2021: 31 · 2020: 48 · 2019: 58 · 2018: 49 · 2017: 49 · 2016: 51 · 2015: 55 · 2014: 62 · 2013: 72 · 2012: 70
FWCI: 18.73
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of the American Geriatrics Society (publishedVersion)
PubMed (publishedVersion)
Funders: Eli Lilly and Company
Topics: Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
Keywords: frailty, older adults, disability prevention, functional decline, clinical trial design, participant recruitment, participant retention, sample size determination, dropout, informed consent
MeSH terms: Activities of Daily Living, Aged, Chronic Disease, Geriatrics, Persons with Disabilities, Health Priorities, Humans, Mass Screening, Periodicals as Topic, Planning Techniques, Primary Prevention, Public Health, Publishing, Research Design, Risk Factors, Geriatric Assessment, Randomized Controlled Trials as Topic, Frail Elderly, Outcome Assessment, Health Care, Sample Size, Disease Progression, Patient Selection

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks