Clinical experience with a helical bipolar stimulating lead
Abstract
Over 100 patients have been treated for partial epilepsy using a NeuroCybernetic Prosthesis System (NCP). The NCP System is comprised of an implantable pulse generator, an implantable bipolar stimulating lead, and an external communication system. The lead delivers electrical impulses from the NCP Generator to the vagus nerve, and includes a connector end that plugs into the generator, a silicone insulated lead body, and the helical electrode array that attaches to the nerve. The surgical implantation technique has a significant impact on lead reliability and performance. The lead electrode has performed well to date. Modifications to further improve reliability have been implemented. Clinical experience, case history examples, and voltage measurements are examined. The lead electrode is an important component of the overall system and plays a significant part in the success of vagus nerve stimulation therapy.
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Large mechanical and geometrical mismatches still exist at the neural interfaces of first-generation extraneural electrodes.
“Large mechanical and geometrical mismatches still exist at the neural interfaces.”
From Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording (2019) · cites this paper as [6]
First-generation extraneural electrodes, including traditional 3D cuff electrodes, helical electrodes, and flat interface nerve electrodes, are made of silicone rubber and platinum.
“the first-generation extraneural electrodes, including traditional 3D cuff electrodes, helical electrodes, and flat interface nerve electrodes, are made of silicone rubber (thickness, ~0.5 mm; modulus, ~2 MPa) and platinum (thickness, ~25 μm; modulus, ~200 GPa) (5–8).”
From Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording (2019) · cites this paper as [6]
Existing extraneural electrodes have at least one of the following drawbacks: large mechanical and geometrical mismatches and complicated surgical implantation procedures.
“Although promising, existing extraneural electrodes have at least one of the following drawbacks: large mechanical and geometrical mismatches and complicated surgical implantation procedures.”
From Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording (2019) · cites this paper as [6]
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- Authors
- TARVER, W. B., GEORGE, R. E., MASCHINO, S. E., HOLDER, L. K., & WERNICKE, J. F.
- Affiliations
- Webster Vienna Private University (AT)
- Baylor College of Medicine (US)
- Corresponding author
- TARVER, W. BRENT
- Venue
- Pacing and Clinical Electrophysiology
- Publisher
- Wiley
- Published
- 1992-10
- Volume
- 15
- Issue
- 10
- Pages
- 1545-1556
- ISSN
- 0147-8389 (ISSN-L)
- 1540-8159
- OpenAlex
- W1996475512
- Cited by
- 46
- References
- 14
- Citations by year
- 2025: 1 · 2020: 4 · 2019: 2 · 2018: 3 · 2017: 1 · 2015: 2 · 2013: 1 · 2012: 3
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pacing and Clinical Electrophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Keywords
- vagus nerve stimulation, focal epilepsy, implantable pulse generator, surgical implantation technique, voltage measurement
- MeSH terms
- Adolescent, Adult, Electrodes, Implanted, Electric Stimulation Therapy, Epilepsies, Partial, Equipment Design, Equipment Failure, Humans, Male, Vagus Nerve, Prostheses and Implants
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