Cited by 121Skin Protection and AgingAntioxidant Activity and Oxidative StressSpectroscopy Techniques in Biomedical and Chemical Research

Carotenoids in human skin

Open access
Lademann, Juergen, Meinke, Martina C., Sterry, Wolfram, Darvin, Maxim E.·2011·Experimental Dermatology

Abstract

The interaction of free radicals with antioxidants is a topic of increasing interest in the development of prevention strategies against skin ageing. Carotenoids can serve as marker substances for the complete antioxidative network of human skin. Recently, it has become possible to measure the carotenoids non-invasively and online using resonance Raman spectroscopy. This method has been used in various studies to investigate the interaction of carotenoid antioxidants and free radicals in human skin. In this review, the results of the selected studies are summarized and compared. It could be demonstrated that the carotenoid concentration of the skin reflects the lifestyle of individuals. A high level of carotenoids can be achieved with a healthy diet rich, for instance, in fruit and vegetables. Stress factors such as illness, UV and IR radiation of the sun, and smoking and alcohol consumption reduce the concentration of the carotenoids in the skin. It could be demonstrated that premature skin ageing was less in people with a high level of antioxidants in their tissue. Consequently, the furrows and wrinkles were not so deep and dense as in the skin of individuals with a low antioxidant level. The measurements are highly suited for the development of anti-ageing strategies and can be efficiently used in the medical diagnostics and therapy control.

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Crossref · 10.1111/j.1600-0625.2010.01189.x

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8 of 8 references verified0 citation errors · 0 not checkable

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  • Vegetables and fruits contain a wide range of antioxidants.

    “Vegetables and fruits, for instance, contains a wide range of antioxidants [19].”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [19]

  • Dietary ingredients with antioxidant qualities are essential for protecting the skin from oxidative stress, either individually or in combination.

    “In addition to enhancing the structural qualities of the skin, dietary ingredients with antioxidant qualities (among others) are essential for protecting the skin from oxidative stress, either individually or in combination [34].”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [34]

  • One of the most effective ways to prevent skin aging is to regularly consume fruits and vegetables that are high in biologically active components.

    “One of the most effective ways to prevent skin aging is to regularly consume fruits and vegetables that are high in biologically active components [33, 34].”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [34]

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Authors
Lademann, J., Meinke, M. C., Sterry, W., & Darvin, M. E.
Affiliations
Charité – Universitätsmedizin Berlin (DE)
Venue
Experimental Dermatology
Publisher
Wiley
Published
2011-03-01
Volume
20
Issue
5
Pages
377-382
ISSN
0906-6705 (ISSN-L)
OpenAlex
W1684141870
Cited by
121
References
8
Citations by year
2026: 2 · 2025: 9 · 2024: 5 · 2023: 12 · 2022: 12 · 2021: 9 · 2020: 2 · 2019: 14 · 2018: 4 · 2017: 4 · 2016: 6 · 2015: 6 · 2014: 11 · 2013: 8 · 2012: 11
FWCI
15.39
Type
journal article
Language
en
Open access
Locations
  • Experimental Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
Keywords
carotenoids, human skin, skin aging, free radicals, antioxidants, resonance Raman spectroscopy, non-invasive measurement, ultraviolet radiation, smoking, alcohol consumption, wrinkles, medical diagnostics
MeSH terms
Carotenoids, Free Radicals, Humans, Life Style, Skin, Skin Aging

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