Cited by 113Skin Protection and AgingAntioxidant Activity and Oxidative StressPhytochemicals and Antioxidant Activities

Carotenoids and UV Protection

Sies, Helmut, Stahl, Wilhelm·2004·Photochemical & Photobiological Sciences

Abstract

Photooxidative processes play a role in the pathobiochemistry of various disorders of light-exposed tissue. After irradiation of skin with UV light, erythema (sunburn) is an initial effect suitable for monitoring the direct biological response. Carotenoids are efficient in photoprotection, scavenging singlet oxygen and peroxyl radicals. Intervention studies with supplements or a carotenoid-rich diet documented efficiency in systemic photoprotection, measuring a decreased sensitivity against UV-induced erythema. For successful intervention, treatment with carotenoids is needed for a period of at least ten weeks. An increased consumption of carotenoids may contribute to life-long protection against UV-induced damage.

Integrity signals

Registry

Crossref · 10.1039/b316082c

Cites

37 of 37 references verified0 citation errors · 0 not checkable

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  • Carotenoids' photoprotective qualities are linked to their antioxidant activities, which effectively scavenge reactive oxygen species, such as superoxide anions, singlet molecular oxygen, hydroxyl radicals and hydrogen peroxide.

    “Carotenoids' photoprotective qualities are linked to their antioxidant activities, which effectively scavenge reactive oxygen species, such as superoxide anions, singlet molecular oxygen, hydroxyl radicals and hydrogen peroxide (Sies and Stahl 2004).”

    From Skin protection from solar ultraviolet radiation using natural compounds: a review (2024) · cites this paper as Sies and Stahl 2004

  • A carotenoid-rich diet decreases erythema size upon UV radiation exposure, but at least ten weeks is necessary for successful intervention.

    “The photoprotective effects of several carotenoids have been investigated by intervention studies in humans, in which a carotenoid-rich diet has been investigated for its ability to decrease the erythema size upon UV radiation exposure [104–106], even though a long period (at least ten weeks) is necessary for successful intervention [106].”

    From Antioxidants from Plants Protect against Skin Photoaging (2018) · cites this paper as [106]

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Authors
Sies, H., & Stahl, W.
Affiliations
Heinrich Heine University Düsseldorf (DE)
Venue
Photochemical & Photobiological Sciences
Published
2004-08
Volume
3
Issue
8
Pages
749-752
ISSN
  • 1474-905X (ISSN-L)
  • 1474-9092
OpenAlex
W2074590131
Cited by
113
References
39
Citations by year
2026: 3 · 2025: 4 · 2024: 3 · 2023: 12 · 2022: 6 · 2021: 7 · 2020: 2 · 2019: 6 · 2018: 5 · 2017: 4 · 2016: 2 · 2015: 5 · 2014: 7 · 2013: 2 · 2012: 7
FWCI
1.17
Type
journal article
Language
en
Open access
closed
Locations
  • Photochemical & Photobiological Sciences (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
carotenoids, UV protection, sunburn, erythema, singlet oxygen scavenging, peroxy radicals, photooxidation, dietary carotenoids, UV-induced skin damage
MeSH terms
Animals, Carotenoids, Free Radicals, Humans, Neoplasms, Radiation-Protective Agents, Ultraviolet Rays

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