Carotenoids and UV Protection
Abstract
Photooxidative processes play a role in the pathobiochemistry of various disorders of light-exposed tissue. After irradiation of skin with UV light, erythema (sunburn) is an initial effect suitable for monitoring the direct biological response. Carotenoids are efficient in photoprotection, scavenging singlet oxygen and peroxyl radicals. Intervention studies with supplements or a carotenoid-rich diet documented efficiency in systemic photoprotection, measuring a decreased sensitivity against UV-induced erythema. For successful intervention, treatment with carotenoids is needed for a period of at least ten weeks. An increased consumption of carotenoids may contribute to life-long protection against UV-induced damage.
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Carotenoids' photoprotective qualities are linked to their antioxidant activities, which effectively scavenge reactive oxygen species, such as superoxide anions, singlet molecular oxygen, hydroxyl radicals and hydrogen peroxide.
“Carotenoids' photoprotective qualities are linked to their antioxidant activities, which effectively scavenge reactive oxygen species, such as superoxide anions, singlet molecular oxygen, hydroxyl radicals and hydrogen peroxide (Sies and Stahl 2004).”
From Skin protection from solar ultraviolet radiation using natural compounds: a review (2024) · cites this paper as Sies and Stahl 2004
A carotenoid-rich diet decreases erythema size upon UV radiation exposure, but at least ten weeks is necessary for successful intervention.
“The photoprotective effects of several carotenoids have been investigated by intervention studies in humans, in which a carotenoid-rich diet has been investigated for its ability to decrease the erythema size upon UV radiation exposure [104–106], even though a long period (at least ten weeks) is necessary for successful intervention [106].”
From Antioxidants from Plants Protect against Skin Photoaging (2018) · cites this paper as [106]
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- Authors
- Sies, H., & Stahl, W.
- Affiliations
- Heinrich Heine University Düsseldorf (DE)
- Venue
- Photochemical & Photobiological Sciences
- Published
- 2004-08
- Volume
- 3
- Issue
- 8
- Pages
- 749-752
- ISSN
- 1474-905X (ISSN-L)
- 1474-9092
- OpenAlex
- W2074590131
- Cited by
- 113
- References
- 39
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 3 · 2023: 12 · 2022: 6 · 2021: 7 · 2020: 2 · 2019: 6 · 2018: 5 · 2017: 4 · 2016: 2 · 2015: 5 · 2014: 7 · 2013: 2 · 2012: 7
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Photochemical & Photobiological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- carotenoids, UV protection, sunburn, erythema, singlet oxygen scavenging, peroxy radicals, photooxidation, dietary carotenoids, UV-induced skin damage
- MeSH terms
- Animals, Carotenoids, Free Radicals, Humans, Neoplasms, Radiation-Protective Agents, Ultraviolet Rays
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