The 5′ flanking region of the monogamous prairie vole oxytocin receptor gene directs tissue-specific expression in transgenic mice
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Comparisons of about 1500 bp of 5' flanking regions from the Oxtr gene reveal only a few SNPs and 99% homology between prairie and montane voles.
“Comparisons of ~1500 bp of 5’ flanking regions from the Oxtr gene reveal only a few SNPs and 99% homology between the species (63).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [63]
Cites
Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles
Insel, T. R., & Shapiro, L. E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.5981 · Cited by 833 · see citing works
Self-citationGonadal steroids have paradoxical effects on brain oxytocin receptors
Insel, T. R., Young, L., Witt, D. M., & Crews, D. (1993) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1993.tb00531.x · Cited by 113 · see citing works
Self-citationYoung, L. J., Huot, B., Nilsen, R., Wang, Z., & Insel, T. R. (1996) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1996.05188.x · Cited by 110 · see citing works
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Insel, T. R. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.005 · Cited by 1,044 · see citing works
Self-citationNeuropeptidergic regulation of affiliative behavior and social bonding in animals
Lim, M. M., & Young, L. J. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.06.028 · Cited by 624 · see citing works
Self-citationA neurobiological basis of social attachment.
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.6.726 · Cited by 553 · see citing works
The neurobiology of pair bonding: Insights from a socially monogamous rodent
Young, K. A., Gobrogge, K. L., Liu, Y., & Wang, Z. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.07.006 · Cited by 389 · see citing works
Self-citationNeuroendocrine bases of monogamy
Young, L. J., Wang, Z., & Insel, T. R. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01167-3 · Cited by 265 · see citing works
Self-citationOxytocin and Vasopressin Receptors and Species-Typical Social Behaviors
Young, L. J. (1999) · Hormones and Behavior · doi:10.1006/hbeh.1999.1548 · Cited by 211 · see citing works
Self-citationKing, L. B., Walum, H., Inoue, K., Eyrich, N. W., & Young, L. J. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.12.008 · Cited by 191 · see citing works
“the reporter in the brain in a pattern resembling prairie voles (64), suggesting the sequence may suffice for some aspects of brain region-specific expression.”
Self-citationYoung, K. A., Liu, Y., & Wang, Z. (2008) · Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology · doi:10.1016/j.cbpc.2008.02.004 · Cited by 163 · see citing works
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- Authors
- YOUNG, L. J., WAYMIRE, K. G., NILSEN, R., MACGREGOR, G. R., WANG, Z., & INSEL, T. R.
- Affiliations
- Emory University (US)
- Corresponding author
- YOUNG, L. J.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 1997-01
- Volume
- 807
- Issue
- 1
- Pages
- 514-517
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2121103027
- Cited by
- 20
- References
- 3
- Citations by year
- 2020: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of the New York Academy of Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Animal Genetics and Reproduction
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Keywords
- oxytocin receptor gene, 5'-flanking region, tissue-specific gene expression, transgenic mice, promoter regulation, social behavior
- MeSH terms
- Animals, beta-Galactosidase, Brain, Arvicolinae, Kidney, Limbic System, Mice, Transgenic, Organ Specificity, Recombinant Fusion Proteins, Regulatory Sequences, Nucleic Acid, Sexual Behavior, Animal, Social Behavior, Receptors, Oxytocin, Mice
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