Aminolevulinic acid and methyl aminolevulinate equally effective in topical photodynamic therapy for non-melanoma skin cancers
Abstract
BACKGROUND: Topical photodynamic therapy (PDT) is an effective treatment for superficial non-melanoma skin cancers. Two prodrugs, 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL), are available for clinical use. There is, however, a lack of studies comparing the clinical effectiveness of these two prodrugs. OBJECTIVE: The objective of the study was to compare the clinical response between ALA- and MAL-PDT when treating actinic keratosis (AK), Bowen's disease (BD), nodular basal cell carcinoma (nBCC) and superficial basal cell carcinoma (sBCC). METHODS: During the period 2002-2009, patients with AK, BD, nBCC and sBCC were treated with ALA- and MAL-PDT at the Department of Dermatology at Karlskoga Hospital in Sweden using a fixed protocol. All patients were followed up approximately 6 months after treatment to evaluate the clinical results, which were analysed retrospectively. RESULTS: In total, 116 patients with 203 tumours were treated with PDT during the study period. ALA- and MAL-PDT were used for 24 vs. 44 AK fields, 9 vs. 18 BD lesions, 19 vs. 25 nBCCs and 25 vs. 39 sBCCs. Response rates with ALA- and MAL-PDT, respectively, were 63% and 75% for AK, 89% and 78% for BD, 84% and 84% for nBCC and 88% and 87% for sBCC. There were no statistically significant differences in the complete clinical response rates for ALA- and MAL-PDT when used for any of the four lesion types. CONCLUSION: ALA- and MAL-PDT appear to be equally effective in the treatment of AK, BD, nBCC and sBCC. Nevertheless, larger, prospective, randomized and controlled studies should be carried out to confirm these results.
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A study comparing ALA/PDT to MAL/PDT with 9 and 18 Bowen's disease lesions, respectively, showed an 89% and 78% response rate, respectively, at approximately 6 months after treatment.
“A study comparing ALA/PDT to MAL/PDT with 9 and 18 Bowen’s disease lesions, respectively, showed an 89% and 78% response rate, respectively, at approximately 6 months after treatment [59].”
From Photodynamic Therapy for Non-Melanoma Skin Cancers (2016) · cites this paper as [59]
Cites
Braathen, L. R., Szeimies, R., Basset‐Séguin, N., Bissonnette, R., Foley, P. A., Pariser, D. M., Roelandts, R., Wennberg, A., & Morton, C. A. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2006.06.006 · Cited by 658 · see citing works
Guidelines for topical photodynamic therapy: update
Morton, C. A., McKenna, K. E., & Rhodes, L. E. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08882.x · Cited by 469 · see citing works
Morton, C. A., Szeimies, R. ‐., Sidoroff, A., & Braathen, L. R. (2013) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12031 · Cited by 344 · see citing works
Rkein, A. M., & Ozog, D. (2014) · Dermatologic Clinics · doi:10.1016/j.det.2014.03.009 · Cited by 239 · see citing works
Peng, Q., Soler, A. M., Warloe, T., Nesland, J. M., & Giercksky, K.-E. (2001) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/s1011-1344(01)00173-7 · Cited by 218 · see citing works
Dirschka, T., Radny, P., Dominicus, R., Mensing, H., Brüning, H., Jenne, L., Karl, L., Sebastian, M., Oster‐Schmidt, C., Klövekorn, W., et al. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10613.x · Cited by 182 · see citing works
Photodynamic Therapy for the Treatment of Basal Cell Carcinoma
Wilson, B. D. (1992) · Archives of Dermatology · doi:10.1001/archderm.1992.04530010035004 · Cited by 177 · see citing works
Gupta, A. K., & Paquet, M. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12343 · Cited by 133 · see citing works
Moloney, F. J., & Collins, P. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.07946.x · Cited by 128 · see citing works
Important Factors for Pain during Photodynamic Therapy for Actinic Keratosis
Sandberg, C., Stenquist, B., Rosdahl, I. K., Ros, A., Synnerstad, I., Karlsson, M., Gudmundson, F., Ericson, M. B., Larkö, O., & Wennberg, A.-M. (2006) · Acta Dermato Venereologica · doi:10.2340/00015555-0098 · Cited by 112 · see citing works
KUIJPERS, D. I. M., Thissen, M. R. T. M., Thissen, C. A. C. B., & NEUMANN, M. H. A. M. (2006) · PubMed · Cited by 102 · see citing works
Foley, P., Freeman, M., Menter, A., Siller, G., El‐Azhary, R. A., Gebauer, K., Lowe, N. J., Jarratt, M. T., Murrell, D. F., Rich, P., et al. (2009) · International Journal of Dermatology · doi:10.1111/j.1365-4632.2008.04022.x · Cited by 92 · see citing works
Vijlder, H., Sterenborg, H., Neumann, H., Robinson, D., & Haas, E. (2012) · Acta Dermato Venereologica · doi:10.2340/00015555-1448 · Cited by 89 · see citing works
Neittaanmäki, N., Karppinen, T. T., Grönroos, M., Tani, T. T., & Snellman, E. (2014) · British Journal of Dermatology · doi:10.1111/bjd.13326 · Cited by 74 · see citing works
Truchuelo, M. T., Fernández-Guarino, M., Fleta, B., Alcántara, J., & Jaén, P. (2011) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2011.04175.x · Cited by 59 · see citing works
Ko, D., Kim, K., & Song, K. (2014) · Annals of Dermatology · doi:10.5021/ad.2014.26.3.321 · Cited by 36 · see citing works
Gold, M. H. (2009) · PubMed · Cited by 35 · see citing works
Mikolajewska, P., Iani, V., Juzeniene, A., & Moan, J. E. (2009) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2009.09437.x · Cited by 35 · see citing works
Photodynamic therapy in the treatment of basal cell carcinoma.
Matei, C., Tampa, M. Ş., Potecă, T. D., Panea-Paunica, G., Georgescu, S. R., Ion, R., Popescu, S. M., & Giurcăneanu, C. (2013) · Europe PMC (PubMed Central) · Cited by 33 · see citing works
Sandberg, C., Paoli, J., Gillstedt, M., Halldin, C. B., Larkö, O., Wennberg, A., & Ericson, M. B. (2011) · Acta Dermato Venereologica · doi:10.2340/00015555-1068 · Cited by 32 · see citing works
Self-citationde Bruijn, H. S., Casas, A. G., Di Venosa, G., Gandara, L., Sterenborg, H. J. C. M., Batlle, A., & Robinson, D. J. (2013) · Photochemical & Photobiological Sciences · doi:10.1039/c2pp25287b · Cited by 31 · see citing works
Juzeniene, A., Juzenas, P., & Moan, J. E. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-697-9_7 · Cited by 18 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions
van Straten, D., Mashayekhi, V., de Bruijn, H., Oliveira, S., & Robinson, D. J. (2017) · Cancers · doi:10.3390/cancers9020019 · Cited by 1,023 · see citing works
Topical treatments for skin cancer
Cullen, J. K., Simmons, J. L., Parsons, P. G., & Boyle, G. M. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.11.002 · Cited by 197 · see citing works
Cameron, M. C., Lee, E. J., Hibler, B. P., Giordano, C. N., Barker, C. A., Mori, S., Cordova, M. A., Nehal, K. S., & Rossi, A. (2018) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.02.083 · Cited by 154 · see citing works
Photodynamic Therapy for Non-Melanoma Skin Cancers
Cohen, D., & Lee, P. (2016) · Cancers · doi:10.3390/cancers8100090 · Cited by 128 · see citing works
Implications of photodynamic cancer therapy: an overview of PDT mechanisms basically and practically
Sobhani, N., & Samadani, A. A. (2021) · Journal of the Egyptian National Cancer Institute · doi:10.1186/s43046-021-00093-1 · Cited by 87 · see citing works
Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management
Naik, P. P., & Desai, M. B. (2022) · Oncology and Therapy · doi:10.1007/s40487-022-00201-8 · Cited by 83 · see citing works
The use of photodynamic therapy in medical practice
Aebisher, D., Rogóż, K., Myśliwiec, A., Dynarowicz, K., Wiench, R., Cieślar, G., Kawczyk‐Krupka, A., & Bartusik‐Aebisher, D. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1373263 · Cited by 80 · see citing works
Advancements and emerging trends in photodynamic therapy: innovations in cancer treatment and beyond
El-Sadek, M. Z., El‐Aziz, M. K. A., Shaaban, A., Mostafa, S. A., & Wadan, A. S. (2025) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-025-00765-0 · Cited by 63 · see citing works
NIR-activated multifunctional agents for the combined application in cancer imaging and therapy
Repetowski, P., Warszyńska, M., & Dąbrowski, J. M. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103356 · Cited by 45 · see citing works
Sun, J., Zhao, H., Fu, L., Cui, J., & Yang, Y. (2023) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s401206 · Cited by 44 · see citing works
Heppt, M. V., Steeb, T., Leiter, U., & Berking, C. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15459 · Cited by 42 · see citing works
Photodynamic therapy for Bowen’s Disease (squamous cell carcinoma in situ) current review and update
O’Connell, K. A., Okhovat, J., & Zeitouni, N. C. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.09.009 · Cited by 41 · see citing works
Kibbi, N., Zhang, Y., Leffell, D. J., & Christensen, S. R. (2019) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2019.10.079 · Cited by 35 · see citing works
Wang, B., Fu, C., Li, Q., Zeng, X.-Y., & Liu, Q. (2020) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2020.101667 · Cited by 35 · see citing works
Howley, R., Mansi, M., Shinde, J., Restrepo, J., & Chen, B. (2020) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/j.jphotobiol.2020.112017 · Cited by 25 · see citing works
Badon, I. W., Kim, C., Lim, J. M., Mai, D. K., Vales, T. P., Kang, D., Cho, S., Lee, J., Kim, H., & Yang, J. (2022) · Journal of Materials Chemistry B · doi:10.1039/d1tb02393d · Cited by 25 · see citing works
Photodynamic Therapy for Photodamage, Actinic Keratosis, and Acne in the Cosmetic Practice
Moy, L. S., Frost, D., & Moy, S. (2019) · Facial Plastic Surgery Clinics of North America · doi:10.1016/j.fsc.2019.09.012 · Cited by 22 · see citing works
Chemical peelings for the treatment of actinic keratosis: a systematic review and meta‐analysis
Steeb, T., Koch, E. A. T., Wessely, A., Wiest, L., Schmitz, L., Berking, C., & Heppt, M. V. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.16844 · Cited by 19 · see citing works
An insight into photodynamic therapy towards treating major dermatological conditions
Dey, A., Singhvi, G., Puri, A., Kesharwani, P., & Dubey, S. K. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.103751 · Cited by 19 · see citing works
Yazdanyar, S., Zarchi, K., & Jemec, G. B. E. (2017) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2017.07.010 · Cited by 19 · see citing works
Yang, X., Palasuberniam, P., Myers, K. A., Wang, C., & Chen, B. (2016) · Oncotarget · doi:10.18632/oncotarget.11058 · Cited by 18 · see citing works
Niculescu, L., Bierhoff, E., Hartmann, D., Ruzicka, T., Berking, C., & von Braunmühl, T. (2017) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2017.01.185 · Cited by 18 · see citing works
Alique-García, S., Alique-García, S., Sánchez, A., Núñez, A. H., & Borbujo, J. M. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.08.011 · Cited by 17 · see citing works
Palasuberniam, P., Kraus, D., Mansi, M. S., Howley, R., Braun, A., Myers, K. A., & Chen, B. (2021) · Journal of Biomedical Optics · doi:10.1117/1.jbo.26.9.098002 · Cited by 16 · see citing works
Zhang, G., Cao, Z. W., Wang, P., Zhu, L., Zhang, L., Zho, Z., Shi, L., & Wang, X. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.101605 · Cited by 16 · see citing works
Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin
Drucker, A. M., Adam, G. P., Langberg, V., Gazula, A., Smith, B., Moustafa, F. A., Weinstock, M. A., & Trikalinos, T. A. (2017) · doi:10.23970/ahrqepccer199 · Cited by 16 · see citing works
Petzold, A., Wessely, A., Steeb, T., Berking, C., & Heppt, M. V. (2024) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.20267 · Cited by 15 · see citing works
Application of microneedling in photodynamic therapy: A systematic review
Tian, R., Wang, X., Li, Y., Zhang, L., & Wen, X. (2024) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2024.104016 · Cited by 14 · see citing works
Photodynamic Therapy with 5-Aminolevulinic Acid Patch for the Treatment of Actinic Keratosis
Kiss, N., Farkas, K., Tosti, G., Gado, F. D., Bergler-Czop, B. S., Fazia, G., Tammaro, A., & Cantisani, C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11113164 · Cited by 14 · see citing works
Textile-integrated polymer optical fibers for healthcare and medical applications
Yamada, Y. (2020) · Biomedical Physics & Engineering Express · doi:10.1088/2057-1976/abbf5f · Cited by 14 · see citing works
Bartosińska, J., Szczepanik-Kułak, P., Raczkiewicz, D., Niewiedzioł, M., Gerkowicz, A., Kowalczuk, D., Kwaśny, M., & Krasowska, D. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14020346 · Cited by 13 · see citing works
Antonetti, P., Pellegrini, C., Caponio, C., Bruni, M., Dragone, L., Mastrangelo, M., Esposito, M., & Fargnoli, M. C. (2024) · Biomedicines · doi:10.3390/biomedicines12040795 · Cited by 13 · see citing works
Improved photodynamic activity of a dual phthalocyanine–ALA photosensitiser
Pavani, C., Francisco, C. M. L., Gobo, N. R. S., de Oliveira, K. T., & Baptista, M. S. (2016) · New Journal of Chemistry · doi:10.1039/c6nj02073a · Cited by 12 · see citing works
Nestor, M. S., Han, H., Ceci, F. M., Lawson, A., & Gade, A. (2023) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.15886 · Cited by 11 · see citing works
Zeitouni, N. C., Schlesinger, T. E., Kheterpal, M., Jolly, P. S., & Jagdeo, J. R. (2025) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2025.104649 · Cited by 11 · see citing works
Photodynamic Therapy and Skin Cancer
Papakonstantinou, E., Löhr, F., & Raap, U. (2018) · InTech eBooks · doi:10.5772/intechopen.70309 · Cited by 9 · see citing works
Meng, Y., Chen, S., Li, P., Wang, C., & Ni, X. (2024) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c01247 · Cited by 8 · see citing works
Morala, J. N., Mascaraque, M., Gallego-Rentero, M., Barahona, A., Lachén, E. A., Carrasco, E., Gilaberte, Y., González, S., & Juarranz, Á. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.94883 · Cited by 8 · see citing works
Rodriguez-Marquez, E., Nord, H., Sánchez, D. P., Kassem, A., Castán, J. M. A., Deiana, M., Cabanetos, C., Sabouri, N., & von Hofsten, J. (2025) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.5c00061 · Cited by 7 · see citing works
Karshieva, S. S., Glinskaya, E. G., Dalina, A. A., Akhlyustina, E. V., Makarova, E. A., Khesuani, Y. D., Chmelyuk, N. S., Abakumov, M. A., Khochenkov, D. A., Mironov, V. A., et al. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103202 · Cited by 7 · see citing works
Mohedano-Muñoz, M. A., Alique-García, S., Rubio-Sánchez, M., Raya, L., & Sánchez, A. (2021) · Expert Systems with Applications · doi:10.1016/j.eswa.2021.114605 · Cited by 7 · see citing works
Gómez, C., Cobos, M., & Alberdi, E. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.04.011 · Cited by 7 · see citing works
Targeting Glycosylation Aberrations to Improve the Efficiency of Cancer Phototherapy
Poiroux, G., Barre, A., Rougé, P., & Benoist, H. (2018) · Current Cancer Drug Targets · doi:10.2174/1568009618666180628101059 · Cited by 7 · see citing works
de Oliveira, E. R., Inada, N. M., Blanco, K. C., Bagnato, V. S., & Sálvio, A. G. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.101603 · Cited by 6 · see citing works
Lima, C. A., Goulart, V. P., Bechara, E. J. H., Côrrea, L., & Zezéll, D. M. (2016) · Journal of Biophotonics · doi:10.1002/jbio.201600164 · Cited by 6 · see citing works
Soto‐Moreno, A., Montero‐Vílchez, T., Díaz‐Calvillo, P., Molina‐Leyva, A., & Arias‐Santiago, S. (2023) · Skin Research and Technology · doi:10.1111/srt.13493 · Cited by 4 · see citing works
Dermatologic Surgery and Procedures
Vereecken, P. (2018) · InTech eBooks · doi:10.5772/66008 · Cited by 4 · see citing works
Shan, F., Zhang, L., Wang, P., Shi, L., Zhang, H., Liao, C., Zhao, Z., Zhou, Z., Zhao, Y., Yan, G., et al. (2024) · Clinical and Experimental Dermatology · doi:10.1093/ced/llae139 · Cited by 3 · see citing works
Schweizer, T. A., Würmli, J. S., Prinz, J., Wölfle, M., Marti, R., Koliwer‐Brandl, H., Rooney, A. M., Benvenga, V., Egli, A., Imhof, L., et al. (2025) · Microorganisms · doi:10.3390/microorganisms13010204 · Cited by 3 · see citing works
Photodynamic therapy: Basics and new directions for clinical applications
Popiel, A., Kr̨ecicki, T., & Kozieł, R. (2025) · Polymers in Medicine · doi:10.17219/pim/208132 · Cited by 2 · see citing works
Jiang, M., Li, D., Huang, Y., & Zhang, Q. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1802984 · Cited by 2 · see citing works
Topical Photodynamic Therapy in a Medical Centre: The Scottish Dermatology Experience
Chaiyabutr, C., Dawe, R. S., Lesar, A. E., & Ibbotson, S. H. (2025) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.70010 · Cited by 2 · see citing works
Kadbhane, A. S., Dahikar, S. B., & Bhutada, S. A. (2025) · Asian Journal of Research in Pharmaceutical Sciences · doi:10.52711/2231-5659.2025.00023 · Cited by 2 · see citing works
Study of ALA and small dosage of HPD photodynamic therapy (HPD-PDT) in treatment of skin cancer
Lü, W., Feng, W., Tang, Y., Tao, X., & Pan, L. (2017) · Biomedical Research-tokyo · Cited by 2 · see citing works
Arenberger, P., & Ettler, J. (2016) · Onkologie · doi:10.36290/xon.2016.015 · Cited by 1 · see citing works
Kubrak, T. P., & Aebisher, D. (2025) · Springer eBooks · doi:10.1007/978-3-642-36202-6_268-1 · Cited by 1 · see citing works
Update on Noninvasive Diagnostic Imaging and Management of Nonmelanoma Skin Cancer
Levine, A., Siegel, D. M., & Markowitz, O. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0207-z · Cited by 1 · see citing works
The Immunogenetic Aspects of Photodynamic Therapy
Lee, C., & Wong, T. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-92616-8_18 · Cited by 1 · see citing works
Vulvovaginal photodynamic therapy in genital erosive lichen planus
Helgesen, A. L. O. (2016) · NORA - Norwegian Open Research Archives
Photodynamic Therapy for Malignant Skin Lesions
Puyana, C., Bunney, R., Kaminska, E. C. N., Pei, S., & Tsoukas, M. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-15130-9_126
ALA-PDT in Nonmelanoma Skin Cancer
Zhang, G., Wang, P., Li, C., Zhao, Z., Li, J., Chang, Q., Wang, B., & Wang, X. (2025) · Springer eBooks · doi:10.1007/978-981-96-8915-6_5
Mantareva, V. N., Braikova, D., Sun, M., & Zhang, J. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48050441
Current Perspectives on Photodynamic Therapy for Skin Diseases: A Narrative Review
Beutler, K., Nowicka, D., & Chilicka, K. (2026) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s614649
- Authors
- Tarstedt, M., Gillstedt, M., Wennberg Larkö, A. ‐., & Paoli, J.
- Affiliations
- Department of Dermatology Karlskoga Hospital Karlskoga Sweden
- Sahlgrenska University Hospital (SE)
- Department of Dermatology and Venereology Sahlgrenska University Hospital Institute of Clinical Sciences at the Sahlgrenska Academy University of Gothenburg Gothenburg Sweden
- Corresponding author
- Paoli, J.
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2016-02-03
- Volume
- 30
- Issue
- 3
- Pages
- 420-423
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- OpenAlex
- W2320951753
- Cited by
- 63
- References
- 22
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 8 · 2023: 4 · 2022: 7 · 2021: 3 · 2020: 4 · 2019: 8 · 2018: 7 · 2017: 5 · 2016: 6
- FWCI
- 8.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the European Academy of Dermatology and Venereology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Keywords
- topical photodynamic therapy, 5-aminolevulinic acid, methyl aminolevulinate, non-melanoma skin cancer, actinic keratosis, Bowen's disease, nodular basal cell carcinoma, superficial basal cell carcinoma, treatment response
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aminolevulinic Acid, Basal Cell Carcinoma, Carcinoma, Basal Cell, Female, Follow-Up Studies, Humans, Male, Melanoma, Middle Aged, Retrospective Studies, Skin Neoplasms, Treatment Outcome, Photosensitizing Agents
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