American Geriatrics Society Abstracted Clinical Practice Guideline for Postoperative Delirium in Older Adults
Open accessAbstract
The abstracted set of recommendations presented here provides essential guidance both on the prevention of postoperative delirium in older patients at risk of delirium and on the treatment of older surgical patients with delirium, and is based on the 2014 American Geriatrics Society ( AGS ) Guideline. The full version of the guideline, American Geriatrics Society Clinical Practice Guideline for Postoperative Delirium in Older Adults is available at the website of the AGS . The overall aims of the study were twofold: first, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the prevention of postoperative delirium in older adults; and second, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the treatment of postoperative delirium in older adults. Prevention recommendations focused on primary prevention (i.e., preventing delirium before it occurs) in patients who are at risk for postoperative delirium (e.g., those identified as moderate‐to‐high risk based on previous risk stratification models such as the National Institute for Health and Care Excellence ( NICE ) guidelines, Delirium: Diagnosis, Prevention and Management . Clinical Guideline 103; London (UK): 2010 July 29). For management of delirium, the goals of this guideline are to decrease delirium severity and duration, ensure patient safety and improve outcomes.
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Several clinical management guidelines for delirium have been published, including from NICE and the American Geriatrics Society, emphasizing prevention with multicomponent non-pharmacological approaches.
“Several clinical management guidelines for delirium have been published 191 , which include those from the UK National Institute for Health and Care Excellence (NICE) 192 and the American Geriatrics Society 193 . The emphasis is on prevention, with the use of multicomponent non‐pharmacological approaches.”
From Mental health care for older adults: recent advances and new directions in clinical practice and research (2022) · cites this paper as [193]
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The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C., et al. (2011) · BMJ · doi:10.1136/bmj.d5928 · Cited by 33,817 · see citing works
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,577 · see citing works
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C., Reynolds, D. J. M., Gavaghan, D. J., & McQuay, H. J. (1996) · Controlled Clinical Trials · doi:10.1016/0197-2456(95)00134-4 · Cited by 17,582 · see citing works
Zhang, Q., Wang, C., Zheng, M., Li, Y., Li, J., Zhang, L., Shang, X., & Yan, C. (2014) · Cerebrovascular Diseases · doi:10.1159/000369778 · Cited by 11,609 · see citing works
Grading quality of evidence and strength of recommendations
(2004) · BMJ · doi:10.1136/bmj.328.7454.1490 · Cited by 8,477 · see citing works
Dong, Y., Hao, L., Shi, Z., Wang, G., Zhang, Z., & Han, C. (2013) · Urologia Internationalis · doi:10.1159/000351405 · Cited by 4,557 · see citing works
Clinical Practice Guidelines We Can Trust
Board on Health Care Services (2011) · National Academies Press eBooks · doi:10.17226/13058 · Cited by 3,102 · see citing works
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye, S. K., Bogardus, S. T., Charpentier, P. A., Leo-Summers, L. S., Acampora, D., Holford, T. R., & Cooney, L. M. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903043400901 · Cited by 2,904 · see citing works
The American Geriatrics Society 2012 Beers Criteria Update Expert Panel (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2012.03923.x · Cited by 2,578 · see citing works
Inouye, S. K. (2006) · New England Journal of Medicine · doi:10.1056/nejmra052321 · Cited by 2,091 · see citing works
Reducing Delirium After Hip Fracture: A Randomized Trial
Marcantonio, E. R., Flacker, J. M., Wright, R. J., & Resnick, N. M. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49108.x · Cited by 1,344 · see citing works
Finding What Works in Health Care: Standards for Systematic Reviews
Eden, J., Levit, L. A., Berg, A. O., & Morton, S. C. (2013) · Cited by 943 · see citing works
Reuben, D. B., Inouye, S. K., Bogardus, S. T., Baker, D. I., Leo‐Summers, L., & Cooney, L. M. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb03885.x · Cited by 802 · see citing works
The Relationship of Postoperative Delirium With Psychoactive Medications
Marcantonio, E. R. (1994) · JAMA · doi:10.1001/jama.1994.03520190064036 · Cited by 565 · see citing works
Lundström, M., Edlund, A., Karlsson, S., Brännström, B., Bucht, G., & Gustafson, Y. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53210.x · Cited by 387 · see citing works
Occurrence of delirium is severely underestimated in the ICU during daily care
Spronk, P. E., Riekerk, B., Hofhuis, J. G. M., & Rommes, J. H. (2009) · Intensive Care Medicine · doi:10.1007/s00134-009-1466-8 · Cited by 380 · see citing works
A Nurse‐Led Interdisciplinary Intervention Program for Delirium in Elderly Hip‐Fracture Patients
Milisen, K., Foreman, M. D., Abraham, I. L., Geest, S. D., Godderis, J., Vandermeulen, E., Fischler, B., Delooz, H. H., Spiessens, B., & Broos, P. L. O. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49109.x · Cited by 369 · see citing works
Iedema, R. A. M., Allen, S. J., Britton, K., Piper, D. A., Baker, A., Grbich, C. F., Allan, A., Jones, L., Tuckett, A. G., Williams, A. F., et al. (2011) · BMJ · doi:10.1136/bmj.d4423 · Cited by 306 · see citing works
Melatonin decreases delirium in elderly patients: A randomized, placebo‐controlled trial
Alaama, T. Y., Brymer, C. D., Gutmanis, I., Woolmore-Goodwin, S., Esbaugh, J., & Dasgupta, M. (2010) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2582 · Cited by 291 · see citing works
Postoperative delirium in old patients with femoral neck fracture: a randomized intervention study
Lundström, M., Olofsson, B., Stenvall, M., Karlsson, S., Nyberg, L., Englund, U., Borssén, B., Svensson, O., & Gustafson, Y. (2007) · Aging Clinical and Experimental Research · doi:10.1007/bf03324687 · Cited by 287 · see citing works
Inouye, S. K. (2000) · Annals of Medicine · doi:10.3109/07853890009011770 · Cited by 242 · see citing works
Qaseem, A., Snow, V., Owens, D. K., Shekelle, P., & for the Clinical Guidelines Committee of the American College of Physicians (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-153-3-201008030-00010 · Cited by 233 · see citing works
Vidán, M. T., Sánchez, E., Alonso, M. T., Montero, B., Ortíz, J., & Rexach, J. A. S. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02485.x · Cited by 227 · see citing works
An educational intervention can prevent delirium on acute medical wards
Tabet, N. (2005) · Age and Ageing · doi:10.1093/ageing/afi031 · Cited by 197 · see citing works
Multicomponent Targeted Intervention to Prevent Delirium in Hospitalized Older Patients
Rizzo, J. A., Bogardus, S. T., Leo-Summers, L. S., Williams, C. S., Acampora, D., & Inouye, S. K. (2001) · Medical Care · doi:10.1097/00005650-200107000-00010 · Cited by 190 · see citing works
Sultan, S. S. A. (2010) · Saudi Journal of Anaesthesia · doi:10.4103/1658-354x.71132 · Cited by 190 · see citing works
Sustainability and Scalability of the Hospital Elder Life Program at a Community Hospital
Rubin, F. H., Neal, K., Fenlon, K., Hassan, S., & Inouye, S. K. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03243.x · Cited by 186 · see citing works
Preventing delirium in an acute hospital using a non-pharmacological intervention
Martínez, F. T., Tobar, C., Beddings, C. I., Vallejo, G., & Fuentes, P. (2012) · Age and Ageing · doi:10.1093/ageing/afs060 · Cited by 182 · see citing works
The Role of Adherence on the Effectiveness of Nonpharmacologic Interventions
Inouye, S. K., Bogardus, S. T., Williams, C. S., Leo-Summers, L. S., & Agostini, J. V. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.8.958 · Cited by 179 · see citing works
Reducing delirium in elderly patients with hip fracture: a multi‐factorial intervention study
Björkelund, K. B., Hommel, A., Thorngren, K., Gustafson, L., Larsson, S., & LUNDBERG, D. (2010) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2010.02232.x · Cited by 175 · see citing works
Modified Hospital Elder Life Program: Effects on Abdominal Surgery Patients
Chen, C., Lin, M., Tien, Y., Yen, C., Huang, G., & Inouye, S. K. (2011) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2011.05.004 · Cited by 149 · see citing works
Rubin, F. H., Williams, J. T., Lescisin, D. A., Mook, W. J., Hassan, S., & Inouye, S. K. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00744.x · Cited by 125 · see citing works
Zaubler, T. S., Murphy, K., Rizzuto, L., Santos, R., Skotzko, C. E., Giordano, J., Bustami, R. T., & Inouye, S. K. (2013) · Psychosomatics · doi:10.1016/j.psym.2013.01.010 · Cited by 123 · see citing works
Recruitment of volunteers to improve vitality in the elderly: the REVIVE* study
Caplan, G. A., & Harper, E. L. (2007) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2007.01265.x · Cited by 118 · see citing works
Villani, D., & Meghi, P. (2014) · Springer eBooks · doi:10.1007/978-3-319-06118-4_6 · Cited by 83 · see citing works
Effectiveness of a multi-component intervention to reduce delirium incidence in elderly care wards
Holt, R., Young, J. B., & Heseltine, D. (2013) · Age and Ageing · doi:10.1093/ageing/aft120 · Cited by 67 · see citing works
Bell, R. H., Drach, G. W., & Rosenthal, R. A. (2011) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2011.08.004 · Cited by 34 · see citing works
Delirium Prevention for Cognitive, Sensory, and Mobility Impairments
Robinson, S. B., Rich, C. A., Weitzel, T., Vollmer, C., & Eden, B. M. (2008) · Research and theory for nursing practice · doi:10.1891/0889-7182.22.2.103 · Cited by 25 · see citing works
Delirium Prevention for Cognitive, Sensory, and Mobility Impairments
Robinson, S. B., Rich, C., Weitzel, T., et al. (2008) · Research and theory for nursing practice · doi:10.1891/1541-6577.22.2.103 · Cited by 13 · see citing works
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- [1]Hazzard WR Bierman EL Bass JP Perioperative management of the older patient Francis J Principles of Geriatric Medicine and Gerentology New York, NY McGraw-Hill International Book Company 1994 277 286
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- Authors
- The American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults
- Affiliations
- American Geriatrics Society (US)
- Corresponding author
- The American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2014-12-12
- Volume
- 63
- Issue
- 1
- Pages
- 142-150
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- PMC
- PMC5901697
- OpenAlex
- W2581138085
- Cited by
- 561
- References
- 39
- Citations by year
- 2026: 44 · 2025: 51 · 2024: 70 · 2023: 55 · 2022: 68 · 2021: 56 · 2020: 44 · 2019: 43 · 2018: 36 · 2017: 43 · 2016: 35 · 2015: 15 · 2013: 1
- FWCI
- 24.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- NIH
- ADRC
- AGS Foundation for Anesthesia Education and Research
- Covidien and Aspect
- National Institute of Nursing Research
- MedEd Portal/Josiah Macy Foundation
- ORNIM
- Pelvalon
- Medtronics, Inc.
- Karl Storz Endoscopy America
- Covidien
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Keywords
- postoperative delirium, older adults, delirium prevention, delirium management, perioperative care, pharmacological interventions, non-pharmacological treatment, risk stratification, surgical patients, patient safety
- MeSH terms
- Aged, Delirium, Humans, Postoperative Complications, Severity of Illness Index, Geriatric Assessment, Risk Assessment
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