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ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

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Microglia and mast cells generate proinflammatory cytokines in the brain and worsen inflammatory state: Suppressor effect of IL-37

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HMGB1 in nervous system diseases: A common biomarker and potential therapeutic target

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The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway

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Selenium Nanoparticles-Enriched Lactobacillus casei ATCC 393 Prevents Cognitive Dysfunction in Mice Through Modulating Microbiota-Gut-Brain Axis

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Ceramides and diabetes mellitus: an update on the potential molecular relationships

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Ceramides in Parkinson’s Disease: From Recent Evidence to New Hypotheses

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DAMPs in immunosenescence and cancer

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Shaping of Innate Immune Response by Fatty Acid Metabolite Palmitate

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Clemastine improves hypomyelination in rats with hypoxic–ischemic brain injury by reducing microglia-derived IL-1β via P38 signaling pathway

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The role of Locus Coeruleus in neuroinflammation occurring in Alzheimer’s disease

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Pyroptotic cell death in the R6/2 mouse model of Huntington’s disease: new insight on the inflammasome

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Inhibition of inflammasome activation via sphingolipid pathway in acute lung injury by Huanglian Jiedu decoction: An integrative pharmacology approach

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Silica Nanoparticles Cause Activation of NLRP3 Inflammasome in-vitro Model-Using Microglia

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Carvacrol abates NLRP3 inflammasome activation by augmenting Keap1/Nrf-2/p62 directed autophagy and mitochondrial quality control in neuropathic pain

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Inflammasomes: An Emerging Mechanism Translating Environmental Toxicant Exposure Into Neuroinflammation in Parkinson’s Disease

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Molecular Effects of FDA-Approved Multiple Sclerosis Drugs on Glial Cells and Neurons of the Central Nervous System

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To re-examine the intersection of microglial activation and neuroinflammation in neurodegenerative diseases from the perspective of pyroptosis

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The Dichotomous Role of Inflammation in the CNS: A Mitochondrial Point of View

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Down-regulation of DJ-1 Augments Neuroinflammation via Nrf2/Trx1/NLRP3 Axis in MPTP-induced Parkinson’s Disease Mouse Model

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Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity – Probable role of NLRP3 inflammasome and caspase-1

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Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis

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Ceramide in cerebrovascular diseases

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Inflammasome activation in neurodegenerative diseases

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Extracellular tau stimulates phagocytosis of living neurons by activated microglia via Toll-like 4 receptor–NLRP3 inflammasome–caspase-1 signalling axis

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The Role of NLRP3 Inflammasome in Radiation-Induced Cardiovascular Injury

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Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia

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Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection

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The NLRP3 inflammasome as a bridge between neuro-inflammation in metabolic and neurodegenerative diseases

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Poria cocos could ameliorate cognitive dysfunction in APP / PS1 mice by restoring imbalance of Aβ production and clearance and gut microbiota dysbiosis

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Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease

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Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway

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Z-Guggulsterone alleviated oxidative stress and inflammation through inhibiting the TXNIP/NLRP3 axis in ischemic stroke

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Ceramide/Sphingosine 1-Phosphate Axis as a Key Target for Diagnosis and Treatment in Alzheimer’s Disease and Other Neurodegenerative Diseases

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JNK/c-Jun-driven NLRP3 inflammasome activation in microglia contributed to retinal ganglion cells degeneration induced by indirect traumatic optic neuropathy

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Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors

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Ceramides may Play a Central Role in the Pathogenesis of Alzheimer’s Disease: a Review of Evidence and Horizons for Discovery

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Activation of neutral sphingomyelinase 2 through hyperglycemia contributes to endothelial apoptosis via vesicle-bound intercellular transfer of ceramides

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Glial Cell Dynamics in Neuroinflammation: Mechanisms, Interactions, and Therapeutic Implications

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Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection

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Short-Chain Fatty Acids Attenuate 5-Fluorouracil-Induced THP-1 Cell Inflammation through Inhibiting NF-κB/NLRP3 Signaling via Glycerolphospholipid and Sphingolipid Metabolism

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The role of CNS macrophages in streptococcal meningoencephalitis

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Inhibiting Microglia‐Derived NLRP3 Alleviates Subependymal Edema and Cognitive Dysfunction in Posthemorrhagic Hydrocephalus after Intracerebral Hemorrhage via AMPK/Beclin‐1 Pathway

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Liraglutide and Naringenin relieve depressive symptoms in mice by enhancing Neurogenesis and reducing inflammation

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Synaptic Function and Dysfunction in Lysosomal Storage Diseases

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Phospholipid metabolism in innate immunity and inflammation: from basic to clinic

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Fundamental Neurochemistry Review: Lipids across microglial states

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The locus coeruleus neurotoxin, DSP4, and/or a high sugar diet induce behavioral and biochemical alterations in wild-type mice consistent with Alzheimers related pathology

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Lipid signatures of chronic pain in female adolescents with and without obesity

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Lipidomics of the erythrocyte membrane and network pharmacology to explore the mechanism of mangiferin from Anemarrhenae rhizoma in treating type 2 diabetes mellitus rats.

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Dietary Supplementation with Naringin Improves Systemic Metabolic Status and Alleviates Oxidative Stress in Transition Cows via Modulating Adipose Tissue Function: A Lipid Perspective

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Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence

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Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

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Targeting ceramide-induced microglial pyroptosis: Icariin is a promising therapy for Alzheimer's disease

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Multi-Omics Reveals Disrupted Immunometabolic Homeostasis and Oxidative Stress in Adipose Tissue of Dairy Cows with Subclinical Ketosis: A Sphingolipid-Centric Perspective

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Gold nanoclusters for optimizing the general efficacies of herbal medicines on nerve repair after spinal cord injury

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Immunometabolism Reframes Alzheimer’s Disease: From Systemic Dysmetabolism to Glial Rewiring

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The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes

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Gender differences in Alzheimer's may be associated with TLR4-LYN expression in damage associated microglia and neuronal phagocytosis

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Clinical and Genetic Profiles of 5q- and Non-5q-Spinal Muscular Atrophy Diseases in Pediatric Patients

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A novel serum metabolomic panel distinguishes I g G4 ‐related sclerosing cholangitis from primary sclerosing cholangitis

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A-Syn(ful) MAM: A Fresh Perspective on a Converging Domain in Parkinson’s Disease

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You aren't IMMUNE to the ceramides that accumulate in cardiometabolic disease

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Tongfu Xingshen capsule alleviates stroke-associated pneumonia-induced multiple organ injuries by modulating the gut microbiota and sphingolipid metabolism

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Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer’s disease associated with inflammasome activation and ASC speck propagation

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Omega-3FAs Can Inhibit the Inflammation and Insulin Resistance of Adipose Tissue Caused by HHcy Induced Lipids Profile Changing in Mice

Li, J., Zhang, H., Dong, Y., Wang, X., & Wang, G. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.628122 · Cited by 10 · see citing works

Diet‐Induced Obesity in the Rat Impairs Sphingolipid Metabolism in the Brain and This Metabolic Dysfunction Is Transmitted to the Offspring via Both the Maternal and the Paternal Lineage

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Centrality of Myeloid-Lineage Phagocytes in Particle-Triggered Inflammation and Autoimmunity

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Role of ceramides in diabetic foot ulcers (Review)

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Ceramides As Potential New Predictors of the Severity of Acute Coronary Syndrome in Conjunction with SARS-CoV-2 Infection

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Evaluation of Inflammatory Cellular Model by Advanced Bioanalytic and Artificial Intelligence Analyses of Lipids: Lipidomic Landscape of Inflammaging

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Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation

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RESEARCH ARTICLE NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not

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NLRP3 Inflammasome assembly in microglia-induced reactive astrocytes

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NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes

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Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia

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