Is butyrate the link between diet, intestinal microbiota and obesity-related metabolic diseases?

Inflammation and metabolic disorders

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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

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Whole and Isolated Protein Fractions Differentially Affect Gastrointestinal Integrity Markers in C57Bl/6 Mice Fed Diets with a Moderate-Fat Content

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Recreating gut-liver axis during NAFLD onset by using a Caco-2/HepG2 co-culture system

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Long term exposure of human gut microbiota with high and low emulsifier sensitivity to soy lecithin in M-SHIME modelPreprint

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Substituting animal protein with black soymilk reduces advanced glycation end product level and improves gut microbiota composition in obese prediabetic individuals: a randomized crossover intervention trial

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Probiotic Effects on Disease Prevention and Treatment

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Dysbiosis of Gut Microbiome in Neurocritically Ill Patients in Intensive Care: Systematic Review

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Quantitative Sustainability

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MAFLD under the lens: the role of gut microbiota

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The microbial fermentation characteristics depend on both carbohydrate source and heat processing: a model experiment with ileo-cannulated pigs

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Basic mechanisms and potential for treatment of weight and eating disorders

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Functional Properties of Seaweed on Gut Microbiota

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A new biocompatible butyric acid-releasing glucosamine derivative for transdermal delivery

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Foods to Prevent Cardiometabolic Disease: Moving from “Saturated Fat” to “Whole Foods”

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Secretion of angiopoietin-like 4 protein from intestinal cells

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Apigetrin attenuates high fat diet-induced intestinal inflammation and nonalcoholic fatty liver disease (NAFLD) process

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Liver and Nutrition

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Metabolic Regulation of Microbiota and Tissue Response

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Metabolic Profile of Gut Microbiota and Levels of Trefoil Factors in Adults with Different Metabolic Phenotypes of Obesity

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Sialic Acid (Neu5Ac)-Driven Modulation of Intestinal Sialylation as a Novel Approach to Mitigating Allergic Reactions to Shrimp Tropomyosin

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Harnessing Probiotics: Exploring the Role of the Gut Microbiome in Combating Obesity

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Dietary ALoe vera gel and Microbiota Interactions: Influence of Butyrate and Insulin Sensitivity

Yagi, A., Al-Madboly, L. A., Kabbash, A. M., & El‐Aasr, M. (2017) · Journal of Gastroenterology and Hepatology Research · doi:10.17554/j.issn.2224-3992.2017.06.721 · Cited by 2

The role of probiotic supplementation on insulin resistance in obesity associated diabetes: A mini review

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Effects of Obesity and Feeding Avocado Extract on Gut Microbiota and Fecal Metabolomic Profile in Overweight/Obese Cats

Husník, R., Fletcher, J. M., Pilla, R., Ingram, D. K., Gaschen, F. P., Roth, G., Chen, C.-C., & Suchodolski, J. S. (2025) · Microbiology Research · doi:10.3390/microbiolres16080190 · Cited by 1

Bioelectronic Technology for Nutritional Research—a Novel In Vitro Platform for a Better Understanding of Human Gut Barrier Absorption

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Molecular signatures of the gut microbiota that affect longevity

Beyoğlu, D., & Idle, J. R. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.118267 · Cited by 1

Increased cytokine production by monocytes from human subjects who consumed grape powder was not mediated by differences in dietary intake patterns

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Role of the Gut Microbiome and Its Modulation in Neurodegenerative Diseases

Prabhakar, P., & Punnaveetil, S. (2022) · Springer eBooks · doi:10.1007/978-981-16-6703-9_5 · Cited by 1

Combating the Sustained Inflammation Involved in Aging and Neurodegenerative Diseases with Probiotics

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PREBIOTICS FOR ACUTE ISCHEMIC STROKE

Renamastika, S. N., Wahyuningrum, D. R., PUTRI, V. A., & Aisy, R. (2021) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2021v13i5.41110 · Cited by 1

Gut Microbiota in NAFLD Pathogenesis and Possible Dietary-Based StrategiesPreprint

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Produção e avaliação do potencial biológico dos enantiômeros de alfa-terpineol

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Does dietary fat composition matter in multiple sclerosis?

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Fecal Metabolomes in Response to Feed Supplemented with Fermented Parkia biglobosa and Sphenostylis stenocarpa in Obese Rats

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The Role of Prebiotics on Nutrient Sensing and Metabolic Homeostasis in the Small Intestine

Berthiaume, K. A. (2020) · UA Campus Repository (The University of Arizona)

Butyric acid (butyrate)

Пальцын, А. А., & Свиридкина, Н. Б. (2021) · Nauchno-prakticheskii zhurnal «Patogenez» · doi:10.25557/2310-0435.2021.01.79-86

Impact of gut-derived metabollites on substrate metabolism and metabolic health

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THE COMPOSITION OF GUT MICROBIOTA IN PATIENTS WITH HYPERLIPIDEMIA

Kvit, K. B. (2022) · Clinical & experimental pathology · doi:10.24061/1727-4338.xxi.3.81.2022.07

Interactions du dioxyde de titane alimentaire avec l’axe microbiote-système immunitaire : un nouvel acteur dans le développement de désordres métaboliques ?

Lamas, B., Evariste, L., & Houdeau, É. (2022) · Cahiers de Nutrition et de Diététique · doi:10.1016/j.cnd.2022.09.003

Cellulose Butyrate as a Potent Fiber Supplement for Mono-Gastric Animals to Modulate Hindgut Microbiota and Fermentation: In Vitro Evaluations

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Predictable Representation of Metabolic Synthesis Pathways of Vitamins and Short-Chain Fatty Acids in Obese Adults

Shestopalov, A. V., Ganenko, L. A., Kolesnikova, I. M., Grigoryeva, T. V., Vasilyev, I. Y., Naboka, Y. L., Волкова, Н. И., Borisenko, O. V., & Roumiantsev, S. A. (2023) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093023050058

Does resistant starch have an effect on intestinal modulation? An integrative review

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PREDICTION OF VITAMINS AND SHORT-CHAIN FATTY ACIDS SYNTHESIS PATHWAYS IN OBESE ADULTS

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The serum metabolic profile plays a role in mediating the regulatory impact of gut microbiota and its metabolites on susceptibility to obesity in micePreprint

Huang, J., Chen, B., Wen, Y., Luo, Y., Lv, S., Qiu, H., Chen, H., He, L., Feng, B., Yu, Z., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4334026/v1

Diagnostic Value of Short-chain Fatty Acids in Psychoneurology and Methodological Aspects of Quantitative Assessment

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Phytochemicals for Preventing and Treating Chronic Diseases

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Olfaction loss induces cognitive impairment and anxiety behavior in mice via the microbiota- gut-brain axisPreprint

Zhao, X., Xue, C., Wang, Y., Liu, X., Li, R., & Yi, X. (2024) · Research Square · doi:10.21203/rs.3.rs-5386295/v1

Metabolic Profile of Gut Microbiota and Levels of Trefoil Factors in Adults with Different Metabolic Phenotypes of Obesity

Kolesnikova, I. M., Ganenko, L. A., Vasilyev, I., Grigoryeva, T. V., Волкова, Н. И., Roumiantsev, S. A., & Shestopalov, A. V. (2024) · Molecular Biology · doi:10.31857/s0026898424040105

In vitro fermentation characteristics of dietary fibers using fecal inoculum from dogs consuming commercial or grain kefir

Metras, B. N., Oba, P. M., Holt, D. A., Bauer, L. L., Miller, M. J., Dilger, R. N., & Swanson, K. S. (2025) · Journal of Animal Science · doi:10.1093/jas/skaf022

Alterations of Gut Microbiome and Serum Short‐Chain Fatty Acids in Children With Enthesitis‐Related Arthritis

Zheng, Q., Xu, Y., Qian, X., Hu, B., Ma, Q., Guo, L., Dorazio, R. M., & Lu, M. (2025) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.70337

Development of a yogurt drink produced from pigeon pea (Cajanus Cajan (L.) Millsp.) that exhibits glucose-lowering effects in diabetic mice

Sine, Y., Widianto, D., Purwestri, Y. A., & Widodo, W. (2025) · Discover Food · doi:10.1007/s44187-025-00579-0

Role of Gut-Liver Axis in Non-Alcoholic Fatty Liver Disease: A Mini Review

Yaghmaei, H., Taromiha, A., Nojoumi, S. A., Soltanipur, M., Shahshenas, S., Rezaei, M., Mirhosseini, S. M., Hosseini, S. M., & Siadat, S. D. (2025) · Iranian Biomedical Journal · doi:10.61882/ibj.4212 · Cited by 1

Additional file 1 of The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life

Kaczmarczyk, M., Löber, U., Adamek, K., Węgrzyn, D., Skonieczna‐Żydecka, K., Malinowski, D., Łoniewski, I., Markó, L., Ulas, T., Forslund, S. K., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14509527

Effect of Lactoferrin in Obese Children and Adolescents with Metabolic Dysfunction-Associated Steatotic Disease: A Randomized Controlled Study

Amrousy, D. M. E., El‐Afify, D., Sorour, E. A. A.-F., & Elrifaey, S. M. (2026) · Pediatric Drugs · doi:10.1007/s40272-026-00742-9

Multi-omics insights into dietary zinc–mediated reprogramming of the gut–nasal ecosystem in allergic rhinitis

Yan, S., Zhang, Z., Xia, C., Liu, P., Ma, J., Liu, J., Wu, T., Wang, H., & Ma, R. (2026) · Frontiers in Allergy · doi:10.3389/falgy.2026.1801629

Improvement of glucose homeostasis during leptin treatment does not alter the intestinal microbiome in male diabetic UC Davis type-2 diabetes mellitus rats

Martínez-Ruiz, M., Tabor‐Simecka, L., Graham, J. L., Randolph, C., Fox, R., Lan, R. S.-L., Pack, L., LeRoith, T., Stanhope, K. L., Yeruva, L., et al. (2026) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00412.2025

Etude de la perméabilité intestinale au cours de l'obésité humaine

Genser, L. (2017) · theses.fr (ABES) · doi:10.70675/b31dde1bz1941z4398zaa56z406e97d709fa

The Great Bustard ( Otis tarda ) and Common Crane ( Grus grus ) Utilize Food Resources via Gut Microbiota Remodeling During Wintering in the Yellow River Wetlands in Ordos City, Inner Mongolia, China

Gao, L., Fang, H., Pei, H., Li, J., & Liu, L. (2026) · Ecology and Evolution · doi:10.1002/ece3.73814

Maternal Pre-Pregnancy Body Mass Index and Its Impact on Short- and Long-Chain Fatty Acid and Microbiome Profiles of Human Breast Milk in Caucasian Women of Northeast Tennessee

Thomas, K. L., Wahlquist, A. E., & Clark, W. A. (2026) · Nutrients · doi:10.3390/nu18121917

Butyrate and Butyrate-Producing Bacteria in Cardiovascular–Kidney–Metabolic Syndrome

Huang, W. W., Zhou, F. L., Wang, S., Shu, M., Liu, Z., & Gao, L. (2026) · Antioxidants · doi:10.3390/antiox15070812

Alcohol-fluoxetine co-treatment drives gut dysbiosis and intestinal barrier disruption with consequences for neuroimmune signaling in male rats

Rohra-Benítez, S., Sanchez-Marin, L., Ruiz-Martín, P., Moríñigo, M. Á., Попова, О. Н., Pavón, F. J., de Fonseca, F. R., Castro‐Zavala, A., Tapia-Paniagua, S. T., & Serrano, A. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.111103

Gut Microbiota and Metabolic Dysfunction-Associated Steatotic Liver Disease: From Dysbiosis to Metagenomic Insights and Therapeutic Perspectives

Frăsinariu, O. E., Ștreangă, V., Rugina, A. L., Mîndru, D. E., Vintilă, T. C., Bădulescu, O. V., Bararu‐Bojan, I., Lupu, V. V., Ignat, A., Mihai, A., et al. (2026) · Pharmaceuticals · doi:10.3390/ph19071113

The HDAC Inhibitor Butyrate Reduces SOD1 Aggregation and Improves Motor Function in C. elegans and Cellular Models of ALS

Dresel, F. C., Michaelis, M., & Gourlay, C. W. (2026) · International Journal of Cell Biology · doi:10.1155/ijcb/3022967

Gut microbiota- and probiotic-derived bioactive metabolites: mechanisms, evidence, and therapeutic potential in metabolic disorders

Akpor, O. B., & Ajinde, A. O. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1953273

Endoscopic treatment of obesity and metabolic disorders : basic and clinical studies on the effect of the Duodenal-Jejunal bypass liner

de Jonge, C. (2014) · Research Publications (Maastricht University) · doi:10.26481/dis.20140905cj

Butyrate as a Potential Preventive Therapy for Obesity

Kumari, P. M., & Peddha, M. S. (2019) · The Indian Journal of Nutrition and Dietetics · doi:10.21048/ijnd.2019.56.4.23688 · Cited by 2

Butyrate and obesity: Current research status and future prospect

Peng, K., Dong, W., Luo, T., Tang, H., Zhu, W., Huang, Y., & Yang, X. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1098881 · Cited by 81

The Protective Role of Butyrate against Obesity and Obesity-Related Diseases

Coppola, S., Avagliano, C., Calignano, A., & Canani, R. B. (2021) · Molecules · doi:10.3390/molecules26030682 · Cited by 272

Butyrate: A potential mediator of obesity and microbiome via different mechanisms of actions

Güler, M. S., Arslan, S., Ağagündüz, D., Cerqua, I., Pagano, E., Canani, R. B., & Capasso, R. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115420 · Cited by 92

Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

van Deuren, T., Blaak, E. E., & Canfora, E. E. (2022) · Obesity Reviews · doi:10.1111/obr.13498 · Cited by 169