Nodular presentation of Dirofilaria repens infection in a cat mimicking a fibrosarcoma
Abstract
A cat with multiple subcutaneous nodules suggesting a soft tissue sarcoma by physical and computed tomographic examination was diagnosed as being affected by subcutaneous filariosis based on cytologic and ultrasonographic assessments. Nodules were surgically removed and extracted nematodes were identified by PCR as Dirofilaria repens. Furthermore, DNA of Dipetalonema dracunculoides (syn. Acantocheilonema dracunculoides) was detected by PCR, with no evidence of circulating microfilariae. To the best of the authors' knowledge, this represents the first report describing adults of D repens in multiple subcutaneous nodules in a cat. Cytopathologic examination allowed characterization of the parasitic nature of the nodules. Veterinary practitioners should be aware of the possible nodular presentation of D repens in cats and should include D repens in the differential diagnosis of subcutaneous neoformations in the cat.
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Selamectin administration was not effective in preventing subcutaneous dirofilariosis in one cat.
“Selamectin administration was not found to be effective in preventing subcutaneous dirofilariosis in one cat, but this apparent failure could have been due to prophylaxis being stopped before the end of the transmission season. 45”
From Dirofilarioses in cats: European guidelines from the ABCD on prevention and management (2020) · cites this paper as [45]
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Dirofilarioses in cats: European guidelines from the ABCD on prevention and management
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Dirofilaria spp. infection in cats from the Mediterranean basin: diagnosis and epidemiology
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Self-citation
- Authors
- Manzocchi, S., Lendner, M., Piseddu, E., Sebastiani, V., Morabito, S., Daugschies, A., & Pantchev, N.
- Affiliations
- Novara Day Lab – IDEXX Laboratories Italia srl Granozzo con Monticello Italy
- Leipzig University (DE)
- Istituto Veterinario di Novara Granozzo con Monticello Italy
- IDEXX Laboratories (Germany) (DE)
- Corresponding author
- Manzocchi, Simone
- Venue
- Veterinary Clinical Pathology
- Publisher
- Wiley
- Published
- 2016-12-09
- Volume
- 46
- Issue
- 1
- Pages
- 158-163
- ISSN
- 0275-6382 (ISSN-L)
- 1939-165X
- OpenAlex
- W2560851287
- Cited by
- 12
- References
- 25
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 4 · 2017: 1
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Veterinary Clinical Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Keywords
- Dirofilaria repens, cats, subcutaneous nodules, soft tissue sarcoma mimic, differential diagnosis, cytopathology, ultrasonography, surgical excision
- MeSH terms
- Animals, Cat Diseases, Cats, Dirofilariasis, Female, Fibrosarcoma, Microfilariae, Tomography, X-Ray Computed, Dirofilaria repens
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