Differential Acute Effect of High-Intensity Interval or Continuous Moderate Exercise on Cognition in Individuals With Parkinson’s Disease
Abstract
BACKGROUND: People with Parkinson's disease (PD) present cognitive impairments, which deteriorate their quality of life and increase disability. Acute aerobic exercise has demonstrated favorable effects on cognitive function in healthy neurologically individuals, but these effects have a dose-response relationship. Therefore, this study aimed to investigate the acute effects of high-intensity interval training (HIIT) versus continuous moderate-intensity training (MICT) on cognitive functions in people with PD. METHODS: A total of 14 individuals with PD performed cognitive tests, before and after 3 sessions-control session (CON), HIIT, and MICT. HIIT and MICT were performed on a stationary bicycle. HIIT consisted of a 25-minute exercise of high-intensity intervals (1 min) alternated with moderate-intensity intervals (2 min). MICT consisted of a 30-minute moderate-intensity exercise. CON was 30 minutes of seated resting. The cognitive parameters were compared by a mixed-model analysis for repeated measures. RESULTS: Acute effects of exercise were according to its type: MICT-improved immediate auditory memory (P < .01); HIIT-improved immediate auditory memory (P < .02), attention (P < .001), and sustained attention (P < .01); and CON-no effects on cognitive function. CONCLUSIONS: Acute aerobic exercise was able to promote better cognitive performance in people with PD. The effects on cognition were exercise intensity dependent.
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Exercise therapy in the form of endurance training, resistance training, intensive mixed training, or high-intensity interval training resulted in a reduction of clinical symptoms in Parkinson's disease.
“In addition, exercise therapy in the form of endurance training, resistance training, intensive mixed training, or high-intensity interval training (HIIT) resulted in a reduction of clinical symptoms in PD [145,146,147,148,149,150,151,152].”
From BDNF as a Promising Therapeutic Agent in Parkinson’s Disease (2020) · cites this paper as [152]
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BDNF as a Promising Therapeutic Agent in Parkinson’s Disease
Palasz, E., Wysocka, A., Gasiorowska, A., Chalimoniuk, M., Niewiadomski, W., & Niewiadomska, G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21031170 · Cited by 504 · see citing works
- Authors
- Fiorelli, C. M., Ciolac, E. G., Simieli, L., Silva, F. A., Fernandes, B., Christofoletti, G., & Barbieri, F. A.
- ORCID
- Venue
- Journal of Physical Activity and Health
- Publisher
- Human Kinetics
- Published
- 2019-02
- Volume
- 16
- Issue
- 2
- Pages
- 157-164
- ISSN
- 1543-3080 (ISSN-L)
- 1543-5474
- OpenAlex
- W2911009565
- Cited by
- 72
- References
- 46
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 7 · 2023: 10 · 2022: 13 · 2021: 19 · 2020: 5 · 2019: 3
- FWCI
- 6.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Physical Activity and Health (publishedVersion)
- PubMed (publishedVersion)
- UNESP Institutional Repository (São Paulo State University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- Parkinson's disease, high-intensity interval training, moderate-intensity continuous training, acute aerobic exercise, cognitive function, exercise intensity, auditory memory, attention, sustained attention, dose-response relationship
- MeSH terms
- High-Intensity Interval Training, Aged, Aged, 80 and over, Cognition, Female, Humans, Longitudinal Studies, Male, Middle Aged, Parkinson Disease, Quality of Life, Rest, Exercise
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