σ-1 Receptors (σ1 Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export

Lipid rafts and signal transduction

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The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

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THE CAVEOLAE MEMBRANE SYSTEM

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Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

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Cholesterol metabolism in the brain

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The Surface of Lipid Droplets Is a Phospholipid Monolayer with a Unique Fatty Acid Composition

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Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

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Mechanisms of lipid-body formation

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Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems

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Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.

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The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel Subunit

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Regulating ankyrin dynamics: Roles of sigma-1 receptors

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A Caveolin Dominant Negative Mutant Associates with Lipid Bodies and Induces Intracellular Cholesterol Imbalance

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Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS)

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An N‐terminal double‐arginine motif maintains type II membrane proteins in the endoplasmic reticulum.

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Ca2+ Signaling via ς1-Receptors: Novel Regulatory Mechanism Affecting Intracellular Ca2+Concentration

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Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration.

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Mutations in the gene encoding 3β- hydroxysteroid-Δ8,Δ7- isomerase cause X-linked dominant Conradi-Hünermann syndrome

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Interactions of selective serotonin reuptake inhibitors with subtypes of σ receptors in rat brain

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Accumulation of Caveolin in the Endoplasmic Reticulum Redirects the Protein to Lipid Storage Droplets

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On the Control of Lipolysis in Adipocytes

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Caveolin-2 Is Targeted to Lipid Droplets, a New “Membrane Domain” in the Cell

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N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors

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Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands

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Cocaine binding at σ receptors

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Cloning and Structural Analysis of the cDNA and the Gene Encoding the Murine Type 1 Sigma Receptor

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The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test.

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Intracellular sigma1 receptor modulates phospholipase C and protein kinase C activities in the brainstem.

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Sphingolipid transport in eukaryotic cells

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Evidence for a multi-site model of the rat brain σ receptor

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Receptor mechanisms in antipsychotic drug action: focus on sigma receptors

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Nerve Growth Factor-Induced Neurite Sprouting in PC12 Cells Involves ς-1 Receptors: Implications for Antidepressants

Takebayashi, M., Hayashi, T., & Su, T. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.041970 · Cited by 132

The Antidepressant-Like Effect Induced by ς1-Receptor Agonists and Neuroactive Steroids in Mice Submitted to the Forced Swimming Test

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σ Receptor antagonists block the development of sensitization to cocaine

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Haloperidol-sensitive (+)[3H]SKF-10,047 binding sites (σ sites) exhibit a unique distribution in rat brain subcellular fractions

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N-alkyl substituted analogs of the σ receptor ligand BD1008 and traditional σ receptor ligands affect cocaine-induced convulsions and lethality in mice

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Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding

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ς1 Receptor Agonist-Mediated Regulation of N-Methyl-d-aspartate-Stimulated [3H]Dopamine Release Is Dependent upon Protein Kinase C

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Cell Confluence-dependent Remodeling of Endothelial Membranes Mediated by Cholesterol

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Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step

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Isolation of the ERG2 gene, encoding sterol Δ8Δ→7 isomerase, from the rice blast fungus Magnaporthe grisea and its expression in the maize smut pathogen Ustilago maydis

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Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

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MAM: more than just a housekeeper

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The pharmacology of sigma-1 receptors.

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Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application

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The sigma-1 receptor chaperone as an inter-organelle signaling modulator

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Intracellular Dynamics of σ-1 Receptors (σ1 Binding Sites) in NG108-15 Cells

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The potential role of sigma-1 receptors in lipid transport and lipid raft reconstitution in the brain: Implication for drug abuse

Hayashi, T., & Su, T. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.05.009 · Cited by 92

Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction

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Sigma-1 Receptor Remodels Endoplasmic Reticulum Membrane

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Subcellular Localization and Interacellular Dynamics of σ1 Receptors

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