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Regulation of Corticotropin-Releasing Factor Neuronal Systems and Hypothalamic-Pituitary-Adrenal Axis Activity by Stress and Chronic Antidepressant Treatment
Abstract
In a series of experiments, we tested the hypothesis that chronic antidepressant drug administration reduces the synaptic availability of corticotropin-releasing factor (CRF) through one or more effects on CRF gene expression or peptide synthesis. We also determined whether effects of acute or chronic stress on CRF gene expression or peptide concentration are influenced by antidepressant drug treatment. Four-week treatment with venlafaxine, a dual serotonin (5-HT)/norepinephrine (NE) reuptake inhibitor, and tranylcypromine, a monoamine oxidase inhibitor, resulted in an attenuation of acute stress-induced increases in CRF heteronuclear RNA (hnRNA) synthesis in the paraventricular nucleus (PVN). Trends toward the same effect were observed after treatment with the 5-HT reuptake inhibitor fluoxetine, or the NE reuptake inhibitor reboxetine. CRF mRNA accumulation in the PVN during exposure to chronic variable stress was attenuated by concurrent antidepressant administration. Basal CRF hnRNA and mRNA expression were not affected by antidepressant treatment in the PVN or in other brain regions examined. Chronic stress reduced CRF concentrations in the median eminence, but there were no consistent effects of antidepressant drug treatment on CRF, serum corticotropin, or corticosterone concentrations. CRF receptor expression and basal and stress-stimulated HPA axis activity were unchanged after antidepressant administration. These results suggest that chronic antidepressant administration diminishes the sensitivity of CRF neurons to stress rather than alters their basal activity. Additional studies are required to elucidate the functional consequences and mechanisms of this interaction.
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“Interestingly, antidepressant treatment normalizes expression of CRF and CRF 1 receptors in association with remission of depression [329,344,346].”
From Anxiety, depression, and the microbiome: A role for gut peptides (2018) · cites this paper as [346]
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378
Self-citationChronic mild stress-induced anhedonia: A realistic animal model of depression
Willner, P., Muscat, R., & Papp, M. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80194-0 · Cited by 1,160 · cited 1×
“A third experiment used a chronic, variable stress regimen that was adapted from previous studies (Chappell et al., 1986; Willner et al., 1992) and consisted of the schedule as detailed below.”
MethodPhysiology and pharmacology of corticotropin-releasing factor.
Owens, M. J., & Nemeroff, C. B. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06673-6 · Cited by 1,147
Self-citationSimmons, D. M., Arriza, J. L., & Swanson, L. W. (1989) · Journal of Histotechnology · doi:10.1179/his.1989.12.3.169 · Cited by 921
Neurotransmitter Receptor and Transporter Binding Profile of Antidepressants and Their Metabolites
Owens, M. J., Morgan, W. N., Plott, S. J., & Nemeroff, C. B. (1997) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37161-7 · Cited by 676
Self-citationPich, E., Lorang, M., Yeganeh, M., Rodriguez de Fonseca, F., Raber, J., Koob, G., & Weiss, F. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05439.1995 · Cited by 565
Ladd, C. O., Owens, M. J., & Nemeroff, C. (1996) · Endocrinology · doi:10.1210/endo.137.4.8625891 · Cited by 536
Self-citationChappell, P., Smith, M., Kilts, C., Bissette, G., Ritchie, J., Anderson, C., & Nemeroff, C. (1986) · The Journal of Neuroscience · doi:10.1523/jneurosci.06-10-02908.1986 · Cited by 464
Self-citationHerman, J. P., Adams, D., & Prewitt, C. M. (2008) · Neuroendocrinology · doi:10.1159/000126839 · Cited by 462
Research works printed but not linked: 1
- Stout, 1996, CRF1 receptor binding, mRNA expression and signal transduction after chronic antidepressant treatment in rats., Soc Neurosci Abstr, 22, 609.4
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Xu, H., Chen, Z., He, J., Haimanot, S., Li, X., Dyck, L. E., & Li, X. (2006) · Hippocampus · doi:10.1002/hipo.20184 · Cited by 175
Keck, M. E., Welt, T., Müller, M. B., Uhr, M., Ohl, F., Wigger, A., Toschi, N., Holsboer, F., & Landgraf, R. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300040 · Cited by 169
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THOMSON, F. J., & Craighead, M. W. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9518-3 · Cited by 158
Ladd, C. O., Thrivikraman, K. V., Huot, R. L., & Plotsky, P. M. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2004.12.004 · Cited by 145
Givalois, L., Naert, G., Rage, F., IXART, G., Arancibia, S., & Tapia‐Arancibia, L. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.07.002 · Cited by 138
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Ishiwata, H., Shiga, T., & Okado, N. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.03.048 · Cited by 138
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Hill, M. N., Ho, W. ‐. V., Sinopoli, K. J., Viau, V., Hillard, C. J., & Gorzalka, B. B. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301092 · Cited by 118
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Dunlop, B. W., Binder, E. B., Iosifescu, D., Mathew, S. J., Neylan, T. C., Pape, J. C., Carrillo-Roa, T., Green, C., Kinkead, B., Grigoriadis, D., et al. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.06.024 · Cited by 96
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Raone, A., Cassanelli, A., Scheggi, S., Rauggi, R., Danielli, B., & Montis, M. G. D. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.03.027 · Cited by 89
Schüle, C., Baghai, T. C., Eser, D., Häfner, S., Born, C., Herrmann, S., & Rupprecht, R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004324 · Cited by 82
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Schüle, C., Baghai, T. C., Eser, D., & Rupprecht, R. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.52 · Cited by 74
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Budziszewska, B., Jaworska-Feil, L., Tetich, M., Basta‐Kaim, A., Kubera, M., Leśkiewicz, M., & Lasoń, W. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300379 · Cited by 29
Skelton, K. H., Gutman, D. A., Thrivikraman, K. V., Nemeroff, C. B., & Owens, M. J. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0713-3 · Cited by 28
Self-citationWeinstock, M., & Poltyrev, T. (2004) · Psychopharmacology · doi:10.1007/s00213-003-1577-9 · Cited by 28
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Santibañez, M., Gysling, K., & Forray, M. I. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.21023 · Cited by 26
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Kier, A., Han, J., & Jacobson, L. (2004) · Endocrinology · doi:10.1210/en.2004-0650 · Cited by 26
Basta‐Kaim, A., Budziszewska, B., Jaworska-Feil, L., Tetich, M., Kubera, M., Leśkiewicz, M., & Lasoń, W. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.02.008 · Cited by 25
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Poretti, M. B., Sawant, R. S., Rask‐Andersen, M., de Cúneo, M. F., Schiöth, H. B., Pérez, M. F., & Carlini, V. P. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4187-4 · Cited by 22
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Geng, L., Ye, D., Shi, Y., Xu, Z., Pu, M., Li, Z., Li, X., Li, Y., & Zhang, Z. (2014) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12201 · Cited by 17
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Vining, C., Iyer, V., & Bhatnagar, S. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01522.x · Cited by 10
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Gołyszny, M. J., Zielinski, M. W., Paul-Samojedny, M., Pałasz, A., & Obuchowicz, E. (2022) · AIMS neuroscience · doi:10.3934/neuroscience.2022022 · Cited by 9
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Cordner, A., Herwood, M. B., Helmreich, D. L., & Parfitt, D. B. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01214.x · Cited by 9
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Bethea, C. L., & Reddy, A. P. (2012) · Brain Research · doi:10.1016/j.brainres.2012.09.035 · Cited by 5
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Metadata
- Authors
- Stout, S. C., Owens, M. J., & Nemeroff, C. B.
- Affiliations
- Emory University (US)
- ORCID
- Nemeroff, Charles B.
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 2002-03
- Volume
- 300
- Issue
- 3
- Pages
- 1085-1092
- ISSN
- 0022-3565 (ISSN-L)
- OpenAlex
- W2154085228
- Cited by
- 117
- References
- 36
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 3 · 2013: 3 · 2012: 4
- FWCI
- 3.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH042088, P50MH058922, MH58922, MH42088)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- corticotropin-releasing factor, hypothalamic-pituitary-adrenal axis, chronic stress, chronic antidepressant treatment, venlafaxine, tranylcypromine, fluoxetine, reboxetine, paraventricular nucleus, chronic variable stress, CRF neurons, monoamine oxidase inhibitors, serotonin reuptake inhibitors, norepinephrine reuptake inhibitors
- MeSH terms
- Adrenocorticotropic Hormone, Animals, Antidepressive Agents, Autoradiography, Corticotropin-Releasing Hormone, Hypothalamo-Hypophyseal System, Immobilization, Male, Neurons, Pituitary-Adrenal System, Radioimmunoassay, RNA Processing, Post-Transcriptional, RNA, Messenger, Stress, Psychological, Swimming, RNA, Antisense, Rats, Sprague-Dawley, In Situ Hybridization, Receptors, Corticotropin-Releasing Hormone, Rats
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