Cited by 89Neurotransmitter Receptor Influence on BehaviorPsychedelics and Drug StudiesNeuroscience and Neuropharmacology Research

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism

Open access
Meinhardt, Marcus W., Pfarr, Simone, Fouquet, Grégory, Rohleder, Cathrin, Meinhardt, Manuela L., Barroso-Flores, Janet, Hoffmann, Rebecca, Jeanblanc, Jérôme +14 more·2021·Science Advances

Abstract

Alcohol-induced mGluR2 deficits are restored by psilocybin, resulting in a rescue of pathological behaviors in alcoholism.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1126/sciadv.abh2399

Cites

83 of 83 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

1 of the 84 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

  1. [1]UNODC, World Drug Report (2018), pp. 35–42.
  2. [73]L. Lumeng, T. Hawkins, T. Li, Alcohol and Aldehyde Metabolizing Systems (Academic Press, 1977), pp. 537–544.
  3. [85]G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates (Elsevier, ed. 4, 1998).

Cited by

Sorted by citations

Authors
Meinhardt, M. W., Pfarr, S., Fouquet, G., Rohleder, C., Meinhardt, M. L., Barroso-Flores, J., Hoffmann, R., Jeanblanc, J., Paul, E., Wagner, K., Hansson, A. C., Köhr, G., Meier, N., von Bohlen und Halbach, O., Bell, R. L., Endepols, H., Neumaier, B., Schönig, K., Bartsch, D., Naassila, M., Spanagel, R., & Sommer, W. H.
Affiliations
  • Heidelberg University (DE)
  • Inserm (FR)
  • The University of Sydney (AU)
  • Universitätsmedizin Greifswald (DE)
  • Institute for Anatomy and Cell Biology, Universitätsmedizin Greifswald, Greifswald, Germany.
  • Indiana University Indianapolis (US)
  • Forschungszentrum Jülich (DE)
  • University of Cologne (DE)
  • Department of Molecular Biology, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Université de Picardie Jules Verne, INSERM UMRS, 1247 Amiens, France.
Corresponding author
  • Meinhardt, Marcus W.
  • Pfarr, Simone
  • Fouquet, Grégory
  • Spanagel, Rainer
  • Sommer, Wolfgang H.
Venue
Science Advances
Published
2021-11-19
Volume
7
Issue
47
Pages
eabh2399-eabh2399
ISSN
2375-2548 (ISSN-L)
OpenAlex
W3213463597
Cited by
89
References
84
Citations by year
2026: 6 · 2025: 20 · 2024: 25 · 2023: 22 · 2022: 14 · 2021: 2
FWCI
7.26
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Science Advances (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Kölner Universitäts PublikationsServer (Universität zu Köln) (publishedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion, cc-by-nc)
  • HAL (submittedVersion)
Funders
  • European Commission (668863, HORIZON2020)
  • Deutsche Forschungsgemeinschaft (ME 5279/3–1, TRR 265, 402170461)
  • Agence Nationale de la Recherche (ANR-18-NEUR-0007)
  • Bundesministerium für Bildung und Forschung (01ZX1909A, FKZ: 01EW1908, 402170461, FKZ: 01ZX1909A, 01EW1908)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
psilocybin, mGluR2, alcoholism, alcohol craving, executive dysfunction, cognitive flexibility, alcohol seeking, relapse, prefrontal cortex, viral gene delivery, personalized treatment, pharmacological interventions

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review