Arrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

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Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

Masopust, D., Vezys, V., Marzo, A. L., & Lefrançois, L. (2001) · Science · doi:10.1126/science.1058867 · Cited by 1,952

Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

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Phenotypic and functional separation of memory and effector human CD8+ T cells

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Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

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Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine

Amara, R. R. (2001) · Science · doi:10.1126/science.1058915 · Cited by 1,110

Visualizing the generation of memory CD4 T cells in the whole body

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Skewed maturation of memory HIV-specific CD8 T lymphocytes

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Control of Inflammation, Cytokine Expression, and Germinal Center Formation by BCL-6

Dent, A. L., Shaffer, A. L., Yu, X., Allman, D., & Staudt, L. M. (1997) · Science · doi:10.1126/science.276.5312.589 · Cited by 950

BCL-6 Represses Genes that Function in Lymphocyte Differentiation, Inflammation, and Cell Cycle Control

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

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Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

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Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

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Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma

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BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor.

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CD28- T lymphocytes. Antigenic and functional properties

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Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes

Opferman, J. T., Ober, B. T., & Ashton‐Rickardt, P. G. (1999) · Science · doi:10.1126/science.283.5408.1745 · Cited by 380

Disruption of the Bcl6 Gene Results in an Impaired Germinal Center Formation

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Modelling T-cell memory by genetic marking of memory T cells in vivo

Jacob, J., & Baltimore, D. (1999) · Nature · doi:10.1038/21208 · Cited by 308

Suppression of Signal Transducer and Activator of Transcription 3–Dependent B Lymphocyte Terminal Differentiation by Bcl-6

Reljić, R., Wagner, S. D., Peakman, L. J., & Fearon, D. T. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.12.1841 · Cited by 217

Transcriptional repression by the proto-oncogene BCL-6.

Seyfert, V. L., Allman, D., He, Y., & Staudt, L. M. (1996) · PubMed · Cited by 187

Induction of CD8+ T cells using heterologous prime‐boost immunisation strategies

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The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain.

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Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine

Amara, R. R., Villinger, F. J., Altman, J. D., Lydy, S. L., O’Neil, S. P., Staprans, S. I., Montefiori, D. C., Xu, Y., Herndon, J. G., Wyatt, L. S., et al. (2001) · Science · doi:10.1126/science.292.5514.69 · Cited by 133

BAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor

Okabe, S., Fukuda, T., Ishibashi, K., Kojima, S., Okada, S., Hatano, M., Ebara, M., Saisho, H., & Tokuhisa, T. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.7.4235 · Cited by 89

Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Peripheral CD4+T Cells

Spiegel, H. M. L., Ogg, G. S., DeFalcon, E., Sheehy, M. E., Monard, S. P., Haslett, P. A. J., Gillespie, G. M. A., Donahoe, S. M., Pollack, H. J., Borkowsky, W., et al. (2000) · Journal of Virology · doi:10.1128/jvi.74.2.1018-1022.2000 · Cited by 85

In vivo and in vitro studies of immunoglobulin gene somatic hypermutation

Sale, J. E., Bemark, M., Williams, G. T., Jolly, C. J., Ehrenstein, M. R., Rada, C. A., Milstein, C., & Neuberger, M. S. (2001) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2000.0744 · Cited by 22

Affinity maturation of antibodies

Milstein, C. (1991) · Immunology Today · doi:10.1016/0167-5699(91)90164-o · Cited by 17

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067

A human memory T cell subset with stem cell–like properties

Gattinoni, L., Lugli, E., Ji, Y., Pos, Z., Paulos, C. M., Quigley, M. F., Almeida, J. R., Gostick, E., Yu, Z., Carpenito, C., et al. (2011) · Nature Medicine · doi:10.1038/nm.2446 · Cited by 1,974

Lineage relationship and protective immunity of memory CD8 T cell subsets

Wherry, E. J., Teichgräber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni889 · Cited by 1,864

Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells

Bernasconi, N. L., Traggiai, E., & Lanzavecchia, A. (2002) · Science · doi:10.1126/science.1076071 · Cited by 1,304

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

Gattinoni, L., Zhong, X.-S., Palmer, D. C., Ji, Y., Hinrichs, C. S., Yu, Z., Wrzesinski, C., Boni, A., Cassard, L., Garvin, L. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1982 · Cited by 1,031

Vaccination and immunological memory

Lanzavecchia, A. (2003) · Cancer immunity

Bcl-6 Uncouples B Lymphocyte Proliferation from Differentiation

Fearon, D. T., Manders, P., & Wagner, S. D. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0757-4_3 · Cited by 9

The immortality of humoral immunity

Elgueta, R., de Vries, V. C., & Noelle, R. J. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00924.x · Cited by 106

Regulation of Telomere Length and Telomerase in T and B Cells

Weng, N., Hathcock, K. S., & Hodes, R. J. (1998) · Immunity · doi:10.1016/s1074-7613(00)80597-x · Cited by 157

Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes

Opferman, J. T., Ober, B. T., & Ashton‐Rickardt, P. G. (1999) · Science · doi:10.1126/science.283.5408.1745 · Cited by 380