Aging and Genome Maintenance: Lessons from the Mouse?
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Items 101–200 of 553
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- Somatic mutations, genome mosaicism, cancer and agingJan Vijg · 2014 · Current Opinion in Genetics & Development
- A Mouse Model of Accelerated Liver Aging Caused by a Defect in DNA RepairSiobhán Q. Gregg, Verónica Gutiérrez, Andria Rasile Robinson, Tyler B. Woodell, Atsunori Nakao, Mark A. Ross, George K. Michalopoulos, Lora Heather Rigatti, Carrie E. Rothermel, Irene Kamileri et al. · 2011 · Hepatology
- Reduced hematopoietic reserves in DNA interstrand crosslink repair‐deficient Ercc1−/− miceJoanna M. Prasher, Astrid S. Lalai, Claudia Heijmans‐Antonissen, RE Ploemacher, Jan H.J. Hoeijmakers, Ivo P. Touw, Laura J. Niedernhofer · 2005 · The EMBO Journal
- Chronological Aging in Saccharomyces cerevisiaeValter Daniel Longo, Paola Fabrizio · 2011 · Sub-cellular biochemistry/Subcellular biochemistry
- Metabolic integration during the evolutionary origin of mitochondriaSEARCY, Dennis G · 2003 · Cell Research
- Caloric restriction and genomic stabilityA. R. Heydari, Ashwin Unnikrishnan, Lisa F. Ventrella-Lucente, Arlan G Richardson · 2007 · Nucleic Acids Research
- Genome instability, cancer and agingAlexander Y. Maslov, Jan Vijg · 2009 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cellsAlison E. Mungenast, Sandra Siegert, Li‐Huei Tsai · 2015 · Molecular and Cellular Neuroscience
- Ageing, repetitive genomes and DNA damageMichael R. Lieber, Zarir E. Karanjawala · 2004 · Nature Reviews Molecular Cell Biology
- Chromatin structure and DNA damage repairChristoffel Dinant, Adriaan B. Houtsmuller, Wim Vermeulen · 2008 · Epigenetics & Chromatin
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- L2L: a simple tool for discovering the hidden significance in microarray expression dataJohn C Newman, Alan M. Weiner · 2005 · Genome biology
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- CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION—WHAT IS THE CAUSE?Richard F. Spaide, Donald Armstrong, Richard W. Browne · 2003 · Retina
- Nuclear DNA Damage as a Direct Cause of AgingBenjamin P. Best · 2009 · Rejuvenation Research
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- From DNA damage to mutations: All roads lead to agingJan Vijg · 2021 · Ageing Research Reviews
- Well-Being over the Life Span: Semiparametric Evidence from British and German Longitudinal DataChristoph Wunder, Andrea Wiencierz, Johannes Schwarze, Helmut Küchenhoff, Sara Kleyer, Philipp Bleninger · 2009 · The Review of Economics and Statistics
- Stem cells for skeletal muscle repairJ. Shadrach, A. Wagers · 2011 · Philosophical Transactions of the Royal Society B: Biological Sciences
- DNA end joining activity is reduced in Alzheimer's diseaseDeborah A. Shackelford · 2005 · Neurobiology of Aging
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- Telomeres, immune aging and autoimmunityJörg J. Goronzy, Hideki Fujii, Cornelia M. Weyand · 2006 · Experimental Gerontology
- Genes encoding longevity: from model organisms to humansMaris Kuningas, Simon P. Mooijaart, Diana van Heemst, Bas J. Zwaan, P. Eline Slagboom, Rudi G. J. Westendorp · 2008 · Aging Cell
- Decline of nucleotide excision repair capacity in aging Caenorhabditis elegansJoel N. Meyer, Windy A. Boyd, Gregory Albert Azzam, Astrid C. Haugen, Jonathan H. Freedman, Bennett Van Houten · 2007 · Genome biology
- Regulation of cell differentiation by the DNA damage responseMara H. Sherman, Craig H. Bassing, Michael A. Teitell · 2011 · Trends in Cell Biology
- Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescenceAgate Noer, Andrew C. Boquest, Philippe Collas · 2007 · BMC Cell Biology
- Pathology of mouse models of accelerated agingHarkema, L., Youssef, S. A., de Bruin, A. · 2016 · Veterinary Pathology
- Zebrafish as a Genetic Model in Biological and Behavioral Gerontology: Where Development Meets Aging in Vertebrates – A Mini-ReviewShuji Kishi, Barbara E. Slack, Junzo Uchiyama, Irina V. Zhdanova · 2009 · Gerontology
- DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding YeastMartin Weinberger, Feng Li, Anita Paul, Daniel L. Smith, Robert D. Hontz, Jeffrey S. Smith, Marija Vujcic, Keshav Kumar Singh, Joel A. Huberman, William C. Burhans · 2007 · PLoS ONE
- Tolerance analysis of chloroplast OsCu/Zn-SOD overexpressing rice under NaCl and NaHCO3 stressQingjie Guan, Xu Liao, Ming‐Liang He, Xiufeng Li, Zhenyu Wang, Haiyan Ma, Yu Song, Shenkui Liu · 2017 · PLoS ONE
- Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient miceMartijn E.T. Dollé, Rita A. Busuttil, Ana Maria Garcia, S. Wijnhoven, Ellen van Drunen, Laura J. Niedernhofer, Gijsbertus T. J. van der Horst, Jan H.J. Hoeijmakers, Harry VAN STEEG, Jan Vijg · 2006 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- Spartan deficiency causes genomic instability and progeroid phenotypesReeja S. Maskey, Myoung Shin Kim, Darren J. Baker, Bennett G. Childs, Liviu A. Malureanu, Karthik B. Jeganathan, Yuka Machida, Jan M. van Deursen, Yuichi Machida · 2014 · Nature Communications
- Increased oxidative phosphorylation in response to acute and chronic DNA damageLear E. Brace, Sarah C. Vose, Kristopher J. Stanya, Rose Muthoni Gathungu, Vasant R. Marur, Alban Longchamp, Humberto Treviño-Villarreal, Pedro Mejia, Dorathy Vargas, Karen Inouye et al. · 2016 · npj Aging and Mechanisms of Disease
- Molecular Mechanisms of Intervertebral Disc DegenerationSean M. Rider, Shuichi Mizuno, James D. Kang · 2018 · Spine Surgery and Related Research
- Increased p53 activity does not accelerate telomere‐driven ageingGarcía‐Cao, Isabel, García‐Cao, Marta, Tomás‐Loba, Antonia, Martin‐Caballero, Juan, Flores, Juana M, Klatt, Peter, Blasco, María A, Serrano, Manuel · 2006 · The EMBO Reports
- Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromesTohru Minamino, Issei Komuro · 2008 · Nature Clinical Practice Cardiovascular Medicine
- Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cellsGuo, Jia, Hanawalt, Philip C., Spivak, Graciela · 2013 · Nucleic Acids Research
- Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA DioxygenasesPertti Koivisto, Peter Robins, Tomas L. Lindahl, Barbara Sedgwick · 2004 · Journal of Biological Chemistry
- Does Damage to DNA and Other Macromolecules Play a Role in Aging? If So, How?Judith Campisi, Jan Vijg · 2009 · The Journals of Gerontology Series A
- A persistent level of Cisd2 extends healthy lifespan and delays aging in miceChia-Yu Wu, Yi‐Fan Chen, Chih‐Hao Wang, Cheng‐Heng Kao, Hui-Wen Zhuang, Chih‐Cheng Chen, Liang‐Kung Chen, Ralph Kirby, Yau‐Huei Wei, Shih‐Feng Tsai et al. · 2012 · Human Molecular Genetics
- Common aging pathways in worms, flies, mice and humansStuart K. Kim · 2007 · Journal of Experimental Biology
- Aging and nuclear organization: lamins and progeriaLeslie C. Mounkes, Colin L. Stewart · 2004 · Current Opinion in Cell Biology
- DNA Damage: A Main Determinant of Vascular AgingPaula K. Bautista‐Niño, Eliana Portilla-Fernández, Douglas E. Vaughan, A.H. Jan Danser, Anton J.M. Roks · 2016 · International Journal of Molecular Sciences
- Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus ApoptosisMonica M. Horvath, Xuting Wang, Michael A. Resnick, Douglas A. Bell · 2007 · PLoS Genetics
- Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouseElisardo C. Vasquez, Veronica A. Peotta, Agata Lages Gava, Thiago MC Pereira, Silvana S. Meyrelles · 2012 · Journal of Biomedical Science
- Are Anxiety Disorders Associated with Accelerated Aging? A Focus on NeuroprogressionGiampaolo Perna, Giuseppe Iannone, Alessandra Alciati, Daniela Caldirola · 2015 · Neural Plasticity
- Use of Senescence-Accelerated Mouse Model in Bleomycin-Induced Lung Injury Suggests That Bone Marrow-Derived Cells Can Alter the Outcome of Lung Injury in Aged MiceJianguo Xu, E. T. Gonzalez, S. S. Iyer, Valerie Mac, Ana Lucia Mora, Roy L. Sutliff, A. Reed, Kenneth L. Brigham, P. Kelly, Mauricio M. Rojas · 2009 · The Journals of Gerontology Series A
- The role of DNA repair in the pluripotency and differentiation of human stem cellsClarissa Ribeiro Reily Rocha, Letícia Koch Lerner, Oswaldo Keith Okamoto, Maria Carolina Marchetto, Carlos Frederico Martins Menck · 2012 · Mutation Research/Reviews in Mutation Research
- Broad segmental progeroid changes in short-lived Ercc1 −/Δ7 miceDollé, Martijn E.T., Kuiper, Raoul V., Roodbergen, Marianne, Robinson, Joke, de Vlugt, Sisca, Wijnhoven, Susan W. P., Beems, Rudolf B., de la Fonteyne, Liset, de With, Piet, van der Pluijm, Ingrid et al. · 2011 · Pathobiology of Aging & Age-related Diseases
- ‘Accelerated aging’: a primrose path to insight?Miller, Richard A. · 2004 · Aging Cell
- Cellular Senescence in Intervertebral Disc Aging and DegenerationPrashanti R. Patil, Laura J. Niedernhofer, Paul D. Robbins, Joon Lee, Gwendolyn Sowa, Nam N. Vo · 2018 · Current Molecular Biology Reports
- Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcsSilvia Espejel, Peter Klatt, Josiane Ménissier‐de Murcia, Juan Martín‐Caballero, Juana María Flores, Guillermo E. Taccioli, Gilbert de MURCIA, Marı́a A. Blasco · 2004 · The Journal of Cell Biology
- The mitotic checkpoint in cancer and aging: what have mice taught us?Darren J. Baker, Junjie Chen, Jan M. A. van Deursen · 2005 · Current Opinion in Cell Biology
- An overview of underlying causes and animal models for the study of age‐related degenerative disorders of the spine and synovial jointsNam N. Vo, Laura J. Niedernhofer, Luigi Aurelio Nasto, Lloydine J. Jacobs, Paul D. Robbins, James D. Kang, Christopher H. Evans · 2013 · Journal of Orthopaedic Research®
- Genetics and skin agingEvgenia Makrantonaki, Vassiliki Bekou, Christos C. Zouboulis · 2012 · Dermato-Endocrinology
- HGPS and related premature aging disorders: From genomic identification to the first therapeutic approachesPereira, Sandrine, Bourgeois, Patrice, Navarro, Claire, Esteves-Vieira, Vera, Cau, Pierre, De Sandre-Giovannoli, Annachiara, Lévy, Nicolas · 2008 · Mechanisms of Ageing and Development
- The skin as a mirror of the aging process in the human organism – State of the art and results of the aging research in the German National Genome Research Network 2 (NGFN-2)Evgenia Makrantonaki, Christos C. Zouboulis · 2007 · Experimental Gerontology
- Aging and cancer cell biology, 2009Judith Campisi, Paul Yaswen · 2009 · Aging Cell
- DNA damage and repair in the female germline: contributions to ARTJacinta Hope Martin, R. John Aitken, Elizabeth G. Bromfield, Brett Nixon · 2018 · Human Reproduction Update
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- A Dual Role of p21 in Stem Cell AgingZhenyu Ju, Aaheli Roy Choudhury, K. Lenhard Rudolph · 2007 · Annals of the New York Academy of Sciences
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- Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevityJoão Pedro de Magalhães, Richard Faragher · 2008 · BioEssays
- The emerging role of epigenetics in cellular and organismal agingBandyopadhyay, Debdutta, Medrano, Estela E · 2003 · Experimental Gerontology
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- ATM and p21 Cooperate to Suppress Aneuploidy and Subsequent Tumor DevelopmentKate C. Shen, Henry H. Heng, Yaolin Wang, Shu Lu, Guo Liu, Chu‐Xia Deng, S.C. Brooks, Yanru Wang · 2005 · Cancer Research
- DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient MouseRichard S. Maser, Kwok‐Kin Wong, Erguen Sahin, Huili Xia, Maria L. Naylor, Herbert Mason Hedberg, Steven E. Artandi, Ronald Anthony DePinho · 2006 · Molecular and Cellular Biology
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- Retinal Degeneration and Ionizing Radiation Hypersensitivity in a Mouse Model for Cockayne SyndromeTheo G. M. F. Gorgels, Ingrid van der Pluijm, Renata M. C. Brandt, George A. Garinis, Harry VAN STEEG, Gerard J. van den Aardweg, Gerard H. Jansen, Jan M. Ruijter, Arthur A B Bergen, Dirk V. Norren et al. · 2006 · Molecular and Cellular Biology
- A role for the CISD2 gene in lifespan control and human diseaseYi‐Fan Chen, Chia‐Yu Wu, Ralph Kirby, Cheng‐Heng Kao, Ting‐Fen Tsai · 2010 · Annals of the New York Academy of Sciences
- Accelerating aging by mouse reverse genetics: a rational approach to understanding longevityPaul Hasty, Jan Vijg · 2004 · Aging Cell
- Aging-Associated Vascular Phenotype in Mutant Mice With Low Levels of BubR1Matsumoto, Takuya, Baker, Darren J., d’Uscio, Livius V., Mozammel, Gazi, Katusic, Zvonimir S., van Deursen, Jan M. · 2007 · Stroke
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- DNA double-strand breaks: A potential causative factor for mammalian aging?Han Li, James R. Mitchell, Paul Hasty · 2008 · Mechanisms of Ageing and Development
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- Destructive cycles: the role of genomic instability and adaptation in carcinogenesisBrandt L. Schneider · 2004 · Carcinogenesis
- p53: at the crossroad between cancer and ageingCristian Papazoglu, AA Mills · 2007 · The Journal of Pathology
- Biochemical Markers of Aging for Longitudinal Studies in HumansPeter M. Engelfriet, Eugène H.J.M. Jansen, H. Susan J. Picavet, Martijn E.T. Dollé · 2013 · Epidemiologic Reviews
- Premature aging and cancer in nucleotide excision repair-disordersKarin E. M. Diderich, Mohammad A. Alanazi, Jan H.J. Hoeijmakers · 2011 · DNA repair
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- Comparison of mice with accelerated aging caused by distinct mechanismsAditi U. Gurkar, Laura J. Niedernhofer · 2015 · Experimental Gerontology
- Haploinsufficiency in DNA Polymerase β Increases Cancer Risk with Age and Alters Mortality RateDiane Cress Cabelof, Yuji Ikeno, Abraham Nyska, Rita A. Busuttil, Njwen Anyangwe, Jan Vijg, Larry H. Matherly, James D. Tucker, Samuel H. Wilson, Arlan Richardson et al. · 2006 · Cancer Research
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- A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-relatedAlex Alves Freitas, Olga Vasieva, João Pedro de Magalhães · 2011 · BMC Genomics
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