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SIRT Is Required for EDP-Mediated Protective Responses toward Hypoxia–Reoxygenation Injury in Cardiac Cells

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p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα

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Is Sirt1 a miracle bullet for longevity?

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Calorie Restriction and SIRT1 Overexpression Induce Different Gene Expression Profiles in White Adipose Tissue in Association with Metabolic Improvement

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The role of structural biology in the design of sirtuin activators

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Promising drug discovery strategies for sirtuin modulators: what lessons have we learnt?

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Is systemic activation of Sirt1 beneficial for ageing-associated metabolic disorders?

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Sirt1 as a key regulator orchestrating the response to caloric restriction

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Inhibition of GIP signaling extends lifespan without caloric restriction

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Shaping social behavior in an enriched environment

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Flavonostilbenes Isolated from the Stems of Rhamnoneuron balansae as Potential SIRT1 Activators

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NAD+ enhancers as therapeutic agents in the cardiorenal axis

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Early Contextual Fear Memory Deficits in a Double-Transgenic Amyloid-βPrecursor Protein/Presenilin 2 Mouse Model of Alzheimer’s Disease

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Food anticipatory activity on a calorie-restricted diet is independent of Sirt1

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Disruption of Igfbp1 fails to rescue the phenotype of Sirt1−/− mice

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Metabolic Effects of Caloric Restriction

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Regulation of the Immune System in Aging: Focus on Epigenetic Mechanisms

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Role of AMP-activated protein kinase and sirtuins as antiaging proteins

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Molecular, Cellular, and Physiological Characterization of Sirtuin 7 (SIRT7)

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Sirtuins, healthspan, and longevity in mammals

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Age and dietary restriction modulate mitochondrial quality in quadriceps femoris muscle of male mice

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When less is adequate: Protein and calorie restriction boosts immunity and possibly, longevity—but how and why?

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Cassava Root Diet Induces Low Pyruvate Levels

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Aging in Rodents

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Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Upregulation of Sirt1 in Type 2 Diabetes Mellitus

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Signaling Cascades in Heart Failure: From Cardiomyocytes Growth and Survival to Mitochondrial Signaling Pathways

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Does SIRT-1 Mediate Calorie Restriction and Prolong Life?

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REGULATION OF TRANSLATION AND TRANSCRIPTION BY SIRT1: POTENTIAL NOVEL MECHANISMS FOR REGULATING STRESS RESPONSE AND AGING

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Sirtuin Function in Longevity

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Study on the Role of SIRT2 in Stem Cell Aging and Chronic Inflammation

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Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction

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Interaction between Diet and Genes on Longevity

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Metabolic and cellular effects of calorie restriction and whey proteins in experimental obesity

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Ischaemia-Reperfusion-Induced Kidney Injury : Experimental studies on the effects of caloric restriction, AMPK activator AICAR and α2-adrenoceptor agonists in the rat

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Sirtuins as Potential Drug Targets for Metabolic Diseases

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Design and Synthesis of 2-Arylbenzimidazole Analogues as Novel SIRT1 Activators for the Treatment of Type II Diabetes

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Caenorhabditis Elegans Host Cell Factor 1 Modulates Organismal Longevity And Stress Responses Via Coordinated Interactions With Multiple Nuclear Transcription Factors And Regulators

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Behavioral changes and mechanisms – an experimental study on aging in rodents

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Therapeutic potential and challenges of targeting sirtuins in neurodegenerative diseases

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The skinny on SIRT1 regulation

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Cassava cyanocarbohydrate metabolism and proposed prehistoric symbionts

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Functions and Regulation of eukaryotic NAD kinase - an essential enzyme for NADP biosynthesis

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Genetic mechanisms of longevity responses to dietary restriction

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Role of Sirtuins in Aging and Tumorigenesis

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Down Regulation of Sirtuins in the Serum of Frail Elderly as Compared to Non-frail Elderly: Promising Diagnostic Protein Marker for Frailty

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Calorie restriction–the SIR2 connection

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Sirt1 as a key regulator orchestrating the response to caloric restriction

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