Increase in Activity During Calorie Restriction Requires Sirt1
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- Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseasesMargarita R. Ramis, Susana Esteban, Antonio Miralles, Dun‐Xian Tan, Russel Joseph Reiter · 2015 · Mechanisms of Ageing and Development
- SIRT1 Promotes Tumorigenesis and Resistance to Chemotherapy in Hepatocellular Carcinoma and its Expression Predicts Poor PrognosisHsieh-Cheng Chen, Yung‐Ming Jeng, Ray‐Hwang Yuan, Hey‐Chi Hsu, Yuling Chen · 2011 · Annals of Surgical Oncology
- SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- miceSokrates Stein, Nicola Schäfer, Alexander Breitenstein, Christian Besler, Stephan H. Winnik, Christine Lohmann, Kathrin Heinrich, Chad E. Brokopp, Christoph Handschin, Ulf Landmesser et al. · 2010 · Aging
- Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1Charles P. Najt, Salmaan Ahmed Khan, Timothy D. Heden, Bruce A. Witthuhn, Minervo Perez, Jason L. Heier, Linnea E. Mead, Mallory P. Franklin, Kenneth K. Karanja, Mark J. Graham et al. · 2019 · Molecular Cell
- The malate–aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeastErin J. Easlon, Felicia A. Tsang, Craig Skinner, Chen Wang, Su-Ju Lin · 2008 · Genes & Development
- Resveratrol and life extensionBeamon Agarwal, Joseph A. Baur · 2011 · Annals of the New York Academy of Sciences
- Behavioral impairments of the aging ratMikael Altun, Esbjörn Bergman, Erik Edström, Hans Johnson, Brun Ulfhake · 2007 · Physiology & Behavior
- Obesity accelerates ovarian follicle development and follicle loss in ratsNa Wang, Lili Luo, Jin-Jie Xu, Ming-Yan Xu, Xing‐Mei Zhang, Xiaoling Zhou, Wei-Juan Liu, Yu‐Cai Fu · 2013 · Metabolism
- Calorie restriction and the exercise of chromatinAlejandro Vaquero, Danny Reinberg · 2009 · Genes & Development
- SIRT6 in DNA repair, metabolism and ageingDavid B. Lombard, Bjoern Schwer, Frederick W. Alt, Raúl Mostoslavsky · 2008 · Journal of Internal Medicine
- Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCageSven Krackow, Elisabetta Vannoni, Alina Codita, A.H. Mohammed, Francesca Cirulli, Igor Branchi, Enrico Alleva, Anja Reichelt, Antje Willuweit, Vootele Võikar et al. · 2010 · Genes Brain & Behavior
- SIRT2 as a Therapeutic Target for Age-Related DisordersRita Machado de Oliveira, Jana Sarkander, Aleksey G. Kazantsev, Tiago F. Outeiro · 2012 · Frontiers in Pharmacology
- A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.Gregory S. Kelly · 2010 · PubMed
- Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1Ken Shinmura, Kayoko Tamaki, Roberto Bolli · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
- Sirtuins as Novel Targets for Alzheimer's Disease and Other Neurodegenerative Disorders: Experimental and Genetic EvidenceDiego Albani, Letizia Polito, Gianluigi Forloni · 2010 · Journal of Alzheimer s Disease
- IP3Receptors, Mitochondria, and Ca2+Signaling: Implications for AgingJean-Paul Decuypere, Giovanni Monaco, Ludwig Missiaen, Humbert DE SMEDT, Jan B. Parys, Geert Bultynck · 2011 · Journal of Aging Research
- Sirtuins regulate key aspects of lipid metabolismDavid J. Lomb, Gaëlle Laurent, Marcia C. Haigis · 2009 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
- NAD+ flux is maintained in aged mice despite lower tissue concentrationsMcReynolds, Melanie R., Chellappa, Karthikeyani, Chiles, Eric, Jankowski, Connor, Shen, Yihui, Chen, Li, Descamps, Hélène C., Mukherjee, Sarmistha, Bhat, Yashaswini R., Lingala, Siddharth R. et al. · 2021 · Cell Systems
- Sirtuins and Their Relevance to the KidneyChuan‐Ming Hao, Volker H. Haase · 2010 · Journal of the American Society of Nephrology
- Mitochondrial Dysregulation in the Pathogenesis of Diabetes: Potential for Mitochondrial Biogenesis-Mediated InterventionsAnna-Maria Joseph, Denis R. Joanisse, Richard G Baillot, David Albert Hood · 2011 · Experimental Diabetes Research
- SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosisKayvan Zainabadi, Cassie J. Liu, Alison L. M. Caldwell, Leonard Guarente · 2017 · PLoS ONE
- SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial MetabolismXing‐Jie Liang, Toren Finkel, Ding‐Wu Shen, Jun‐Jie Yin, Adorján Aszalós, Michael M. Gottesman · 2008 · Molecular Cancer Research
- Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti‐aging and metabolic effects of sirtuinsIvy Ka Man Law, Ling Liu, Aimin Xu, Karen S.L. Lam, Paul M. Vanhoutte, Chi‐Ming Che, Priscilla T.Y. Leung, Yu Wang · 2009 · PROTEOMICS
- Sirtuin‐independent effects of nicotinamide on lifespan extension from calorie restriction in yeastMitsuhiro Tsuchiya, Nick Dang, Emily O. Kerr, Di Hu, Kristan K. Steffen, Jonathan A. Oakes, Brian Keith Kennedy, Matt R. Kaeberlein · 2006 · Aging Cell
- Redox-regulating sirtuins in aging, caloric restriction, and exerciseZsolt O. Radak, Erika Koltai, Albert W. Taylor, Mitsuru Higuchi, Shuzo Kumagai, Hideki Ohno, Sataro Goto, Istvan R. Boldogh · 2013 · Free Radical Biology and Medicine
- SIRT1 and neuronal diseasesBor Luen Tang, Christelle En Lin Chua · 2007 · Molecular Aspects of Medicine
- Nampt/PBEF/Visfatin: A regulator of mammalian health and longevity?Hongying Yang, Siva Lavu, David A. Sinclair · 2006 · Experimental Gerontology
- SIRT 1 but not its increased expression is essential for lifespan extension in caloric‐restricted miceEvi M. Mercken, Jia Hua Hu, Susan M. Krzysik-Walker, Min Wei, Ying Li, Michael W. McBurney, Rafael de Cabo, Valter Daniel Longo · 2013 · Aging Cell
- Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activationXuben Hou, David W. Rooklin, Hao Fang, Yingkai Zhang · 2016 · Scientific Reports
- The Mysterious Food-Entrainable Oscillator: Insights from Mutant and Engineered Mouse ModelsJulie S. Pendergast, Shin Yamazaki · 2018 · Journal of Biological Rhythms
- Sirtuins in Neuroendocrine Regulation and Neurological DiseasesYuki Fujita, Toshihide Yamashita · 2018 · Frontiers in Neuroscience
- Sir2 and calorie restriction in yeast: A skeptical perspectiveMatt R. Kaeberlein, R. Wilson Powers · 2007 · Ageing Research Reviews
- Long-lived Indy and calorie restriction interact to extend life spanPei‐Yu Wang, Nicola Neretti, Rachel Whitaker, Suzanne Hosier, Cheng-Yi Chang, Daniel Y. Lu, Blanka Rogina, Stephen L. Helfand · 2009 · Proceedings of the National Academy of Sciences
- The role of SIRT1 in ocular agingTatsuya Mimura, Yuichi Kaji, Hidetaka Noma, Hideharu Funatsu, Shinseiro Okamoto · 2013 · Experimental Eye Research
- Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight LossMaura Fanti, Amrendra Kumar Mishra, Valter Daniel Longo, Sebastian Brandhorst · 2021 · Current Obesity Reports
- Nutrient Sensing and the Oxidative Stress ResponseHanzhi Luo, Hou-Hsien Chiang, Makensie Louw, Albert Susanto, Danica Chen · 2017 · Trends in Endocrinology and Metabolism
- Signaling networks in agingEric Lieberman Greer, Anne Brunet · 2008 · Journal of Cell Science
- Abnormal Epigenetic Regulation of Immune System during AgingMiriam Galvonas Jasiulionis · 2018 · Frontiers in Immunology
- Metabolic benefits from Sirt1 and Sirt1 activatorsNilika Chaudhary, Paul T. Pfluger · 2009 · Current Opinion in Clinical Nutrition & Metabolic Care
- Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicityDebariya Dutta, Jinze Xu, Marvin L. S. Dirain, Christiaan Leeuwenburgh · 2014 · Free Radical Biology and Medicine
- At the crossroads of longevity and metabolism: the metabolic syndrome and lifespan determinant pathwaysFadini, Gian Paolo, Ceolotto, Giulio, Pagnin, Elisa, de Kreutzenberg, Saula, Avogaro, Angelo · 2011 · Aging Cell
- Aging epigenetics: Causes and consequencesCovadonga Huidobro, Agustín F. Fernández, Mario F. Fraga · 2012 · Molecular Aspects of Medicine
- Circadian clocks govern calorie restriction—mediated life span extension through BMAL1‐ and IGF‐1‐dependent mechanismsPatel, Sonal A., Chaudhari, Amol, Gupta, Richa, Velingkaar, Nikkhil, Kondratov, Roman V. · 2016 · The FASEB Journal
- SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5pLina Sun, Zheng Zhi, Liangyan Chen, Qun Yong Zhou, Xiuming Li, Wen-Juan Gan, Shu Chen, Meng Yang, Yao Liu, Tong Shen et al. · 2017 · Cancer Letters
- Age-Related Increase in Levels of 5-Hydroxymethylcytosine in Mouse Hippocampus is Prevented by Caloric RestrictionChouliaras, Leonidas, L.A. van den Hove, Daniel, Kenis, Gunter, Keitel, Stella, R. Hof, Patrick, van Os, Jim, W.M. Steinbusch, Harry, Schmitz, Christoph, P.F. Rutten, Bart · 2012 · Current Alzheimer Research
- Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic NephropathyItaru Yasuda, Kazuhiro Hasegawa, Yusuke Sakamaki, Hirokazu Muraoka, Takahisa Kawaguchi, Ei Kusahana, Takashi Ono, Takeshi Kanda, Hirobumi Tokuyama, Shu Wakino et al. · 2021 · Journal of the American Society of Nephrology
- Sirtuin 1 in Endothelial Dysfunction and Cardiovascular AgingStefano Ministrini, Yustina M. Puspitasari, Georgia Beer, Luca Liberale, Fabrizio Montecucco, Giovanni Guido Camici · 2021 · Frontiers in Physiology
- SIRT1: roles in aging and cancerEun-Joo Kim, Soo‐Jong Um · 2008 · BMB Reports
- Metabolic and Neuropsychiatric Effects of Calorie Restriction and SirtuinsSergiy Libert, Leonard Guarente · 2012 · Annual Review of Physiology
- SIRT1 suppresses self-renewal of adult hippocampal neural stem cellsChenyan Ma, Maojin Yao, Qiwei Zhai, Jianwei Jiao, Xiao‐bing Yuan, Mu‐ming Poo · 2014 · Development
- Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70Thimmappa S. Anekonda, Grazyna Adamus · 2008 · BMC Research Notes
- Sirtuins: from metabolic regulation to brain agingWenzhen Duan · 2013 · Frontiers in Aging Neuroscience
- Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neuronsSteven J. Greco, Ashkan Hamzelou, Jane M. Johnston, Mark A. Smith, John Wesson Ashford, Nikolaos Tezapsidis · 2011 · Biochemical and Biophysical Research Communications
- Intersection between metabolic dysfunction, high fat diet consumption, and brain agingRomina María Uranga, Annadora J. Bruce‐Keller, Christopher D. Morrison, Sun Ok Fernandez‐Kim, Philip J. Ebenezer, Le Zhang, Kalavathi Dasuri, Jeffrey N. Keller · 2010 · Journal of Neurochemistry
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- Targeting p53-MDM2-MDMX Loop for Cancer TherapyQi Zhang, Shelya X. Zeng, Hua Lu · 2014 · Sub-cellular biochemistry/Subcellular biochemistry
- Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging—A Systematic ReviewAngelika Bielach-Bazyluk, Edyta Zbroch, Hanna Myśliwiec, Alicja Rydzewska–Rosołowska, Katarzyna Kakareko, Iwona Flisiak, Tomasz Hryszko · 2021 · Cells
- The ageing epigenome: Damaged beyond repair?David A. Sinclair, Philipp Oberdoerffer · 2009 · Ageing Research Reviews
- SIRT1, resveratrol and agingBlanka Rogina, Heidi A. Tissenbaum · 2024 · Frontiers in Genetics
- Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanismJunaith Shaik Mohamed, Joseph C. Wilson, Matthew J. Myers, Kayla J. Sisson, Stephen E. Alway · 2014 · Aging
- Distinct Effects of Calorie Restriction and Resveratrol on Diet-Induced Obesity and Fatty Liver FormationTauriainen, Eveliina, Luostarinen, Mira, Martonen, Essi, Finckenberg, Piet, Kovalainen, Miia, Huotari, Anne, Herzig, Karl-Heinz, Lecklin, Anne, Mervaala, Eero · 2011 · Journal of Nutrition and Metabolism
- The controversial links among calorie restriction, SIRT1, and resveratrolYi Hu, Jing Liu, Junfeng Wang, Qingsong Liu · 2011 · Free Radical Biology and Medicine
- Calorie restriction and the nutrient sensing signaling pathwaysIvanka Dilova, Erin J. Easlon, Su-Ju Lin · 2007 · Cellular and Molecular Life Sciences
- Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restrictionChouliaras, Leonidas, van den Hove, Daniel L.A., Kenis, Gunter, Keitel, Stella, Hof, Patrick R., van Os, Jim, Steinbusch, Harry W.M., Schmitz, Christoph, Rutten, Bart P.F. · 2012 · Neurobiology of Aging
- The Drosophila ARC homolog regulates behavioral responses to starvationMark D. Mattaliano, Enrico S. Montana, Katherine M. Parisky, J. Troy Littleton, Leslie C. Griffith · 2007 · Molecular and Cellular Neuroscience
- The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional OutputsFiorella Ghisays, Cynthia S. Brace, Shawn M. Yackly, Hyock Joo Kwon, Kathryn F. Mills, Elena A. Kashentseva, Igor P. Dmitriev, David T. Curiel, Shin‐ichiro Imai, Tom Ellenberger · 2015 · Cell Reports
- From Obesity to Hippocampal Neurodegeneration: Pathogenesis and Non-Pharmacological InterventionsThomas Ho-yin Lee, Suk‐Yu Yau · 2020 · International Journal of Molecular Sciences
- Ergothioneine and its congeners: anti-ageing mechanisms and pharmacophore biosynthesisLi Chen, Liping Zhang, Xujun Ye, Zixin Deng, Changming Zhao · 2023 · Protein & Cell
- Regulation of yeast sirtuins by NAD+ metabolism and calorie restrictionShu-Ping Lu, Su-Ju Lin · 2009 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
- Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetesShiro Maeda, Daisuke Koya, Shin‐ichi Araki, Tetsuya Babazono, Tomoya Umezono, Masao Toyoda, Koichi Kawai, Masahito Imanishi, Takashi Uzu, Daisuke Suzuki et al. · 2011 · Clinical and Experimental Nephrology
- Molecular Insights into SIRT1 Protection Against UVB-Induced Skin Fibroblast Senescence by Suppression of Oxidative Stress and p53 AcetylationKi Wung Chung, Yeon Ja Choi, Min Hi Park, Eun Ji Jang, Dae Hyun Kim, Byung Hyun Park, Byung Pal Yu, Hae Young Chung · 2014 · The Journals of Gerontology Series A
- Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy agingLaurent Mouchiroud, Laurent Molin, Nicolas Dallière, Florence Solari · 2010 · BioFactors
- Changes in behaviors of male C57BL/6J mice across adult life span and effects of dietary restrictionAndreas Fahlström, Hugo Zeberg, Brun Ulfhake · 2011 · AGE
- Association between low SIRT1 expression in visceral and subcutaneous adipose tissues and metabolic abnormalities in women with obesity and type 2 diabetesYoung Sook Song, Seul Ki Lee, Yeon Jin Jang, Hye Soon Park, Jong-Hyeok Kim, Yeon Ji Lee, Yoon-Suk Heo · 2013 · Diabetes Research and Clinical Practice
- The PPARδ-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependentMin Young Kim, Eun Sil Kang, Sun Ah Ham, Jung Seok Hwang, Tae Sik Yoo, Hanna Lee, Kyung Shin Paek, Chankyu Park, Hoon Taek Lee, Jin‐Hoi Kim et al. · 2012 · Biochemical Pharmacology
- The role of calorie restriction and SIRT1 in prion-mediated neurodegenerationDanica Chen, Andrew D. Steele, Gregor Hütter, Joanne Bruno, Arvind Govindarajan, Erin J. Easlon, Su-Ju Lin, Adriano Aguzzi, Susan Lee Lindquist, Leonard Guarente · 2008 · Experimental Gerontology
- Do Sirtuins Promote Mammalian Longevity?: A Critical Review on Its Relevance to the Longevity Effect Induced by Calorie RestrictionSeongjoon Park, Ryoichi Mori, Isao Shimokawa · 2013 · Molecules and Cells
- Role of Sirtuins and Calorie Restriction in Neuroprotection: Implications in Alzheimers and Parkinsons DiseasesSarika Srivastava, Marcia C. Haigis · 2011 · Current Pharmaceutical Design
- Potential Mechanisms Linking Atherosclerosis and Increased Cardiovascular Risk in COPD: Focus On SirtuinsGraziamaria Corbi, Andrea Bianco, Viviana Turchiarelli, Michele Cellurale, Federica Fatica, Aurora Daniele, Gennaro Mazzarella, Nicola Ferrara · 2013 · International Journal of Molecular Sciences
- Modulation of β-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5Ho, David, Yan, Lin, Iwatsubo, Kousaku, Vatner, Dorothy E., Vatner, Stephen F. · 2010 · Heart Failure Reviews
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- SIRT1 induces resistance to apoptosis in human granulosa cells by activating the ERK pathway and inhibiting NF-κB signaling with anti-inflammatory functionsYing Han, Haining Luo, Hui Wang, Jun Cai, Yunshan Zhang · 2017 · APOPTOSIS
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- Protective Properties of Radio-Chemoresistant Glioblastoma Stem Cell Clones Are Associated with Metabolic Adaptation to Reduced Glucose DependenceFei Ye, Yibei Zhang, Yue Liu, Kazunari Yamada, Jonathan L. Tso, Jimmy C. Menjivar, Jane Y. Tian, William H. Yong, Dörthe Schaue, Paul S. Mischel et al. · 2013 · PLoS ONE
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- Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in miceWei-Juan Liu, Xing‐Mei Zhang, Na Wang, Xiaoling Zhou, Yu‐Cai Fu, Lili Luo · 2015 · European journal of medical research
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