H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Huang, P. L., Huang, Z., Mashimo, H., Bloch, K. D., Moskowitz, M. A., Bevan, J. A., & Fishman, M. C. (1995) · Nature · doi:10.1038/377239a0 · Cited by 2,070

The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener

Zhao, W., Zhang, J., Lu, Y., & Wang, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.6008 · Cited by 1,936

Two's company, three's a crowd: can H 2 S be the third endogenous gaseous transmitter?

Wang, R. T. (2002) · The FASEB Journal · doi:10.1096/fj.02-0211hyp · Cited by 1,808

N OVEL N EURAL M ODULATORS

Boehning, D. F., & Snyder, S. H. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131047 · Cited by 1,235

Elevated blood pressures in mice lacking endothelial nitric oxide synthase

Shesely, E. G., Maeda, N., Kim, H.-S., Desai, K. M., Krege, J. H., Laubach, V. E., Sherman, P. A., Sessa, W. C., & Smithies, O. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.23.13176 · Cited by 908

Homocysteine and vascular disease

McCully, K. S. (1996) · Nature Medicine · doi:10.1038/nm0496-386 · Cited by 705

H2S-induced vasorelaxation and underlying cellular and molecular mechanisms

Zhao, W., & Wang, R. T. (2002) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00013.2002 · Cited by 505

Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats

Cheng, Y., Ndisang, J. F., Tang, G., Cao, K., & Wang, R. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00331.2004 · Cited by 439

Hydrogen Sulfide as a Neuromodulator

Kimura, H. (2002) · Molecular Neurobiology · doi:10.1385/mn:26:1:013 · Cited by 427

Inhibition of Hydrogen Sulfide Generation Contributes to Gastric Injury Caused by Anti-Inflammatory Nonsteroidal Drugs

Fiorucci, S., Antonelli, E., Distrutti, E., Rizzo, G., Mencarelli, A., Orlandi, S., Zanardo, R. C. O., Renga, B., Sante, M. D., Morelli, A., et al. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.07.060 · Cited by 409

Luminescent Chemodosimeters for Bioimaging

Yang, Y., Zhao, Q., Feng, W., & Li, F. (2012) · Chemical Reviews · doi:10.1021/cr2004103 · Cited by 2,244

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

Wang, R. (2012) · Physiological Reviews · doi:10.1152/physrev.00017.2011 · Cited by 1,962

Hydrogen Sulfide and Cell Signaling

Li, L., Rose, P. E., & Moore, P. K. (2011) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010510-100505 · Cited by 1,289

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

Paulsen, C. E., & Carroll, K. S. (2013) · Chemical Reviews · doi:10.1021/cr300163e · Cited by 1,313

H 2 S Signals Through Protein S-Sulfhydration

Mustafa, A. K., Gadalla, M. M., Sen, N., Kim, S., Mu, W., Gazi, S. K., Barrow, R. K., Yang, G., Wang, R., & Snyder, S. H. (2009) · Science Signaling · doi:10.1126/scisignal.2000464 · Cited by 1,243

Chemical Biology of H 2 S Signaling through Persulfidation

Filipović, M. R., Živanović, J., Álvarez, B., & Banerjee, R. V. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00205 · Cited by 1,059

Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

Lin, V., Chen, W., Xian, M., & Chang, C. J. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00298a · Cited by 1,041

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

Wallace, J. L., & Wang, R. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4433 · Cited by 882

Hydrogen sulfide is an endogenous stimulator of angiogenesis

Papapetropoulos, A., Pyriochou, A., Altaany, Z., Yang, G., Marazioti, A., Zhou, Z., Jeschke, M. G., Branski, L. K., Herndon, D. N., Wang, R., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908047106 · Cited by 868

H2S signalling through protein sulfhydration and beyond

Paul, B. D., & Snyder, S. H. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3391 · Cited by 864

Nitric oxide signalling in cardiovascular health and disease

Farah, C., Michel, L. Y. M., & Balligand, J.-L. (2018) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.224 · Cited by 779

Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

Szabó, C., Coletta, C., Chao, C., Módis, K., Szczęsny, B., Papapetropoulos, A., & Hellmich, M. R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306241110 · Cited by 771

Reaction-Based Fluorescent Probes for Selective Imaging of Hydrogen Sulfide in Living Cells

Lippert, A. R., New, E. J., & Chang, C. J. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203661j · Cited by 768

Redox Biochemistry of Hydrogen Sulfide

Kabil, Ö., & Banerjee, R. V. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.r110.128363 · Cited by 745

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

Sen, N., Paul, B. D., Gadalla, M. M., Mustafa, A. K., Sen, T., Xu, R., Kim, S., & Snyder, S. H. (2012) · Molecular Cell · doi:10.1016/j.molcel.2011.10.021 · Cited by 733

Multicenter Metal–Organic Framework‐Based Ratiometric Fluorescent Sensors

Wu, S., Min, H., Shi, W., & Cheng, P. (2019) · Advanced Materials · doi:10.1002/adma.201805871 · Cited by 715

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202916109 · Cited by 677

Development of a Highly Selective Fluorescence Probe for Hydrogen Sulfide

Sasakura, K., Hanaoka, K., Shibuya, N., Mikami, Y., Kimura, Y., Komatsu, T., Ueno, T., Terai, T., Kimura, H., & Nagano, T. (2011) · Journal of the American Chemical Society · doi:10.1021/ja207851s · Cited by 661

Multiphase Chemistry at the Atmosphere–Biosphere Interface Influencing Climate and Public Health in the Anthropocene

Pöschl, U., & Shiraiwa, M. (2015) · Chemical Reviews · doi:10.1021/cr500487s · Cited by 691

Hydrogen sulfide: its production, release and functions

Kimura, H. (2010) · Amino Acids · doi:10.1007/s00726-010-0510-x · Cited by 640

Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels

Mustafa, A. K., Sikka, G., Gazi, S. K., Steppan, J., Jung, S. M., Bhunia, A. K., Barodka, V. M., Gazi, F. K., Barrow, R. K., Wang, R., et al. (2011) · Circulation Research · doi:10.1161/circresaha.111.240242 · Cited by 630

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

Singh, S., Padovani, D., Leslie, R. A., Chiku, T., & Banerjee, R. V. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.010868 · Cited by 615

Endogenous hydrogen sulfide production is essential for dietary restriction benefits

Hine, C., Harputlugil, E., Zhang, Y., Ruckenstuhl, C., Lee, B. C., Brace, L., Longchamp, A., Treviño-Villarreal, J. H., Mejia, P., Ozaki, C. K., et al. (2015) · Cell · doi:10.1016/j.cell.2014.11.048 · Cited by 558

Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe

Liu, C., Pan, J. H., Li, S., Zhao, Y., Wu, L. Y., Berkman, C. E., Whorton, A. R., & Xian, M. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201104305 · Cited by 578

A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria

Chen, Y., Zhu, C., Yang, Z., Chen, J., He, Y., Jiao, Y., He, W., Qiu, L., Cen, J., & Guo, Z. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201207701 · Cited by 563

Hydrogen Sulfide Protects Against Cellular Senescence via S -Sulfhydration of Keap1 and Activation of Nrf2

Yang, G., Zhao, K., Ju, Y., Mani, S., Cao, Q., Puukila, S., Khaper, N., Wu, L., & Wang, R. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4645 · Cited by 571

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

Cirino, G., Szabó, C., & Papapetropoulos, A. (2022) · Physiological Reviews · doi:10.1152/physrev.00028.2021 · Cited by 578

S-adenosylmethionine in Liver Health, Injury, and Cancer

Lu, S. C.-L., & Mato, J. M. (2012) · Physiological Reviews · doi:10.1152/physrev.00047.2011 · Cited by 565

Role of Endothelial Dysfunction in Cardiovascular Diseases: The Link Between Inflammation and Hydrogen Sulfide

Sun, H., Wu, Z., Nie, X.-W., & Bian, J. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01568 · Cited by 558

Targeting vascular (endothelial) dysfunction

Daiber, A., Steven, S., Weber, A., Shuvaev, V. V., Muzykantov, V. R., Laher, I., Li, H., Lamas, S., & Münzel, T. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13517 · Cited by 501

Selective fluorescent probes for live-cell monitoring of sulphide

Qian, Y., Karpus, J., Kabil, Ö., Zhang, S., Zhu, H.-L., Banerjee, R. V., Zhao, J., & He, C. (2011) · Nature Communications · doi:10.1038/ncomms1506 · Cited by 506

Hydrogen sulfide as a gasotransmitter

Gadalla, M. M., & Snyder, S. H. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06580.x · Cited by 493

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

Stipanuk, M. H., & Ueki, I. (2010) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-009-9006-9 · Cited by 498

Signaling by Gasotransmitters

Mustafa, A. K., Gadalla, M. M., & Snyder, S. H. (2009) · Science Signaling · doi:10.1126/scisignal.268re2 · Cited by 503

Hydrogen sulfide chemical biology: pathophysiological roles and detection

Kolluru, G. K., Shen, X., Bir, S. C., & Kevil, C. G. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.07.002 · Cited by 480

Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide

Shibuya, N., Mikami, Y., Kimura, Y., Nagahara, N., & Kimura, H. (2009) · The Journal of Biochemistry · doi:10.1093/jb/mvp111 · Cited by 481

Enzymology of H 2 S Biogenesis, Decay and Signaling

Kabil, Ö., & Banerjee, R. V. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5339 · Cited by 479

Molecular Biology of Atherosclerosis

Hopkins, P. N. (2013) · Physiological Reviews · doi:10.1152/physrev.00004.2012 · Cited by 469

Making and working with hydrogen sulfide

Hughes, M., Centelles, M. N., & Moore, K. P. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.09.018 · Cited by 454

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

Chiku, T., Padovani, D., Zhu, W., Singh, S., Vitvitsky, V., & Banerjee, R. V. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808026200 · Cited by 454

Emergence of Hydrogen Sulfide as an Endogenous Gaseous Signaling Molecule in Cardiovascular Disease

Polhemus, D. J., & Lefer, D. J. (2014) · Circulation Research · doi:10.1161/circresaha.114.300505 · Cited by 442

International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors

Szabó, C., & Papapetropoulos, A. (2017) · Pharmacological Reviews · doi:10.1124/pr.117.014050 · Cited by 423

Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

Montoya, L. A., & Pluth, M. D. (2012) · Chemical Communications · doi:10.1039/c2cc30730h · Cited by 426

The ozone paradox: Ozone is a strong oxidant as well as a medical drug

Bocci, V. A., Borrelli, E., Travagli, V., & Zanardi, I. (2009) · Medicinal Research Reviews · doi:10.1002/med.20150 · Cited by 422

A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?

Cao, X., Ding, L., Xie, Z., Yang, Y., Whiteman, M., Moore, P. K., & Bian, J. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7058 · Cited by 412

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease

Paul, B. D., Sbodio, J. I., Xu, R., Vandiver, M. S., Cha, J. Y., Snowman, A. M., & Snyder, S. H. (2014) · Nature · doi:10.1038/nature13136 · Cited by 407

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

Živanović, J., Kouroussis, E., Kohl, J. B., Adhikari, B., Bursać, B. N., Schott-Roux, S., Petrovic, D., Miljković, J. L., Thomas‐López, D., Jung, Y., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.10.007 · Cited by 401

Hydrogen Sulfide in Biochemistry and Medicine

Predmore, B. L., Lefer, D. J., & Gojon, G. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4612 · Cited by 393

The metabolism and significance of homocysteine in nutrition and health

Kumar, A., Palfrey, H. A., Pathak, R., Kadowitz, P. J., Gettys, T. W., & Murthy, S. N. (2017) · Nutrition & Metabolism · doi:10.1186/s12986-017-0233-z · Cited by 399

Regulators of the transsulfuration pathway

Sbodio, J. I., Snyder, S. H., & Paul, B. D. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14446 · Cited by 379

Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

Mani, S., Li, H., Untereiner, A., Wu, L., Yang, G., Austin, R. C., Dickhout, J. G., Lhoták, Š., Meng, Q. H., & Wang, R. (2013) · Circulation · doi:10.1161/circulationaha.113.002208 · Cited by 377

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

Eberhardt, M. J., Dux, M., Namer, B., Miljković, J. L., Cordasic, N., Will, C., Kichko, T. I., de la Roche, J., Fischer, M. J. M., Suárez, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms5381 · Cited by 387

Hydrogen sulphide, a novel gasotransmitter involved in guard cell signalling

García‐Mata, C., & Lamattina, L. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03465.x · Cited by 376

Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H 2 O 2 -dependent H 2 S production

Lin, V., Lippert, A. R., & Chang, C. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1302193110 · Cited by 379

Hydrogen sulphide enhances photosynthesis through promoting chloroplast biogenesis, photosynthetic enzyme expression, and thiol redox modification in Spinacia oleracea seedlings

Chen, J., Wu, F.-H., Wang, W., Zheng, C., Lin, G., Dong, X.-J., He, J., Pei, Z., & Zheng, H. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err145 · Cited by 369

No facilitator required for membrane transport of hydrogen sulfide

Mathai, J., Missner, A., Kügler, P., Saparov, S. M., Zeidel, M. L., Lee, J. K., & Pohl, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902952106 · Cited by 369

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

King, A. L., Polhemus, D. J., Bhushan, S., Otsuka, H., Kondo, K., Nicholson, C. K., Bradley, J., Islam, K. N., Calvert, J. W., Tao, Y., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321871111 · Cited by 368

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

Whiteman, M., Li, L., Rose, P. E., Tan, C., Parkinson, D. B., & Moore, P. K. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2899 · Cited by 367

H 2 S: A Novel Gasotransmitter that Signals by Sulfhydration

Paul, B. D., & Snyder, S. H. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.08.007 · Cited by 365

H 2 S mediates O 2 sensing in the carotid body

Peng, Y.-J., Nanduri, J., Raghuraman, G., Souvannakitti, D., Gadalla, M. M., Kumar, G. K., Snyder, S. H., & Prabhakar, N. R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005866107 · Cited by 361

Cysteine Metabolism in Neuronal Redox Homeostasis

Paul, B. D., Sbodio, J. I., & Snyder, S. H. (2018) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2018.02.007 · Cited by 356

l ‐Cysteine metabolism and its nutritional implications

Yin, J., Ren, W., Yang, G., Duan, J., Huang, X., Fang, R., Li, C.-Y., Li, Y., Yin, Y., Hou, Y., et al. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500031 · Cited by 355

Signaling Molecules: Hydrogen Sulfide and Polysulfide

Kimura, H. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5869 · Cited by 358

A practical guide to working with H 2 S at the interface of chemistry and biology

Hartle, M. D., & Pluth, M. D. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00212a · Cited by 350

H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

Kondo, K., Bhushan, S., King, A. L., Prabhu, S. D., Hamid, T., Koenig, S. C., Murohara, T., Predmore, B. L., Gojon, G., Gojon, G., et al. (2013) · Circulation · doi:10.1161/circulationaha.112.000855 · Cited by 344

Environmental toxicology of hydrogen sulfide

Malone, S. L., Pearce, L. L., & Peterson, J. (2017) · Nitric Oxide · doi:10.1016/j.niox.2017.09.011 · Cited by 350

Oxidative Stress and Hypertension: Current Concepts

Briones, A. M., & Touyz, R. M. (2010) · Current Hypertension Reports · doi:10.1007/s11906-010-0100-z · Cited by 347

Vascular biology of ageing—Implications in hypertension

Harvey, A., Montezano, A. C., & Touyz, R. M. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.04.011 · Cited by 330

Gasotransmitters: growing pains and joys

Wang, R. (2014) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2014.03.003 · Cited by 342

Hydrogen Sulfide Is an Endogenous Inhibitor of Phosphodiesterase Activity

Bucci, M., Papapetropoulos, A., Vellecco, V., Zhou, Z., Pyriochou, A., Roussos, C., Roviezzo, F., Brancaleone, V., & Cirino, G. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.209783 · Cited by 337

The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art

Esse, R., Barroso, M., de Almeida, I. T., & Castro, R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040867 · Cited by 352

Chemical Characterization of the Smallest S -Nitrosothiol, HSNO; Cellular Cross-talk of H 2 S and S -Nitrosothiols

Filipovic, M. R., Miljkovic, J. L., Nauser, T., Royzen, M., Klos, K., Shubina, T., Koppenol, W. H., Lippard, S. J., & Ivanović-Burmazović, I. (2012) · Journal of the American Chemical Society · doi:10.1021/ja3009693 · Cited by 336

Chemical foundations of hydrogen sulfide biology

Li, Q., & Lancaster, J. R. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.07.001 · Cited by 334

EDHF: an update

Félétou, M., & Vanhoutte, P. M. (2009) · Clinical Science · doi:10.1042/cs20090096 · Cited by 331

Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation — a tale of three gases!

Li, L., Hsu, A., & Moore, P. K. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.05.005 · Cited by 331

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production

Longchamp, A., Mirabella, T., Arduini, A., MacArthur, M. R., Das, A., Trevino-Villarreal, J. H., Hine, C., Ben‐Sahra, I., Knudsen, N. H., Brace, L. E., et al. (2018) · Cell · doi:10.1016/j.cell.2018.03.001 · Cited by 330

Low Levels of Hydrogen Sulfide in the Blood of Diabetes Patients and Streptozotocin-Treated Rats Causes Vascular Inflammation?

Jain, S. K., Bull, R., Rains, J., Bass, P. F., Levine, S. N., Reddy, S., McVie, R., & Bocchini, J. A. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2956 · Cited by 318

Hydrogen Sulfide: From Brain to Gut

Kimura, H. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2919 · Cited by 315

Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

Calvert, J. W., Coetzee, W. A., & Lefer, D. J. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2882 · Cited by 313

Synthesis and application of coumarin fluorescence probes

Sun, X., Liu, T., Sun, J., & Wang, X. (2020) · RSC Advances · doi:10.1039/c9ra10290f · Cited by 326

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

Whiteman, M., Trionnaire, S. L., Chopra, M., Fox, B. C., & Whatmore, J. L. (2011) · Clinical Science · doi:10.1042/cs20110267 · Cited by 310

A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living cells based on thiolysis of dinitrophenyl ether

Cao, X., Lin, W., Zheng, K., & He, L. (2012) · Chemical Communications · doi:10.1039/c2cc34031c · Cited by 304

Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising

Whiteman, M., & Winyard, P. G. (2010) · Expert Review of Clinical Pharmacology · doi:10.1586/ecp.10.134 · Cited by 304

Cysteine Oxidative Posttranslational Modifications

Chung, H. S., Wang, S.-B., Venkatraman, V., Murray, C. I., & Eyk, J. E. V. (2013) · Circulation Research · doi:10.1161/circresaha.112.268680 · Cited by 314

Hydrogen Sulfide Is a Signaling Molecule and a Cytoprotectant

Kimura, H., Shibuya, N., & Kimura, Y. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4345 · Cited by 291

Human Sulfide:Quinone Oxidoreductase Catalyzes the First Step in Hydrogen Sulfide Metabolism and Produces a Sulfane Sulfur Metabolite

Jackson, M. R. C., Melideo, S. L., & Jörns, M. S. (2012) · Biochemistry · doi:10.1021/bi300778t · Cited by 291

Detection of Protein S‐Sulfhydration by a Tag‐Switch Technique

Zhang, D., Mačinković, I., Devarie‐Baez, N. O., Pan, J. H., Park, C., Carroll, K. S., Filipović, M. R., & Xian, M. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201305876 · Cited by 289

Hydrogen sulfide interacting with abscisic acid in stomatal regulation responses to drought stress in Arabidopsis

Jin, Z., Xue, S., Luo, Y., Tian, B., Fang, H., Li, H., & Pei, Y. (2012) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2012.10.017 · Cited by 287

Hydrogen Sulfide: The Third Gasotransmitter in Biology and Medicine

Wang, R. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2938 · Cited by 287

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

Suzuki, K., Oláh, G., Módis, K., Coletta, C., Kulp, G., Gerő, D., Szoleczky, P., Chang, T., Zhou, Z., Wu, L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105121108 · Cited by 287

Chemical aspects of hydrogen sulfide measurements in physiological samples

Nagy, P., Pálinkás, Z., Nagy, A., Budai, B., Tóth, I., & Vasas, A. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.05.037 · Cited by 285

Förster Resonance Energy Transfer Switchable Self-Assembled Micellar Nanoprobe: Ratiometric Fluorescent Trapping of Endogenous H2S Generation via Fluvastatin-Stimulated Upregulation

Zhao, C., Zhang, X., Li, K.-B., Zhu, S., Guo, Z., Zhang, L., Wang, F., Fei, Q., Luo, S., Shi, P., et al. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b03248 · Cited by 282

A Retrievable and Highly Selective Fluorescent Probe for Monitoring Sulfide and Imaging in Living Cells

Hou, F., Huang, L., Xi, P., Cheng, J., Zhao, X., Xie, G., Shi, Y., Cheng, F., Yao, X., Bai, D., et al. (2012) · Inorganic Chemistry · doi:10.1021/ic2024082 · Cited by 278

Sulfur signaling: Is the agent sulfide or sulfane?

Toohey, J. I. (2011) · Analytical Biochemistry · doi:10.1016/j.ab.2011.01.044 · Cited by 276

The Quantitative Significance of the Transsulfuration Enzymes for H 2 S Production in Murine Tissues

Kabil, Ö., Vitvitsky, V., Xie, P., & Banerjee, R. V. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3781 · Cited by 275

Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

Giovinazzo, D., Bursać, B. N., Sbodio, J. I., Nalluru, S., Vignane, T., Snowman, A. M., Albacarys, L. M., Sedlak, T. W., Torregrossa, R., Whiteman, M., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2017225118 · Cited by 274

Synthesis and Biological Effects of Hydrogen Sulfide (H2S): Development of H2S-Releasing Drugs as Pharmaceuticals

Caliendo, G., Cirino, G., Santagada, V., & Wallace, J. L. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm901638j · Cited by 272

A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator

Szabó, C. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.09.010 · Cited by 271

Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H 2 S Gas Biology

Kajimura, M., Fukuda, R., Bateman, R. M., Yamamoto, T., & Suematsu, M. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2657 · Cited by 271

Hydrogen Sulfide in the Mammalian Cardiovascular System

Liu, Y., Lu, M., Hu, L., Wong, P. T. ‐., Webb, G. D., & Bian, J. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4005 · Cited by 264

Blood pressure control: hydrogen sulfide, a new gasotransmitter, takes stage

Zoccali, C., Catalano, C., & Rastelli, S. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp053 · Cited by 34

Hydrogen sulfide: a new gaseous signal molecule and blood pressure regulator

Wagner, C. A. (2009) · Journal of Nephrology · doi:10.1093/joneph/2.22.173 · Cited by 94

Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases

Meng, G., Ma, Y., Xie, L., Ferro, A., & Ji, Y. H. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12900 · Cited by 123

Reply to Olson and Perry: H 2 S physiologically mediates O 2 sensing

Snyder, S. H., Gadalla, M. M., & Prabhakar, N. R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010131107

The Role of Hydrogen Sulfide as an Endogenous Vasorelaxant Factor

Wang, R., Cheng, Y., & Wu, L. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-806-9_19 · Cited by 6