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An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells

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Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity betweenPlasmodium vivaxPvDBP andPlasmodium falciparumVAR2CSA

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HCV Proteins and Immunoglobulin Variable Gene (IgV) Subfamilies in HCV-Induced Type II Mixed Cryoglobulinemia: A Concurrent Pathogenetic Role

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IBC's 21stAnnual Antibody Engineering and 8thAnnual Antibody Therapeutics International Conferences and 2010 Annual Meeting of The Antibody Society

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Expanding the frontiers of protein–protein modeling: From docking and scoring to binding affinity predictions and other challenges

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Comprehensive Analysis of Pathogen-specific Antibody Response in Vivo Based on an Antigen Library Displayed on Surface of Yeast

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Flu Universal Vaccines: New Tricks on an Old Virus

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Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies

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Fighting the flu: a brief review on anti-influenza agents

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Development of an Influenza virus Protein Array Using Sortagging Technology

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Vaccines based on structure-based design provide protection against infectious diseases

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The human side of influenza

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A highly sensitive chemiluminescent metalloimmunoassay for H1N1 influenza virus detection based on a silver nanoparticle label

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Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice

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Breadth of Antibody Responses during Influenza Virus Infection and Vaccination

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H1 Hemagglutinin Priming Provides Long-Lasting Heterosubtypic Immunity against H5N1 Challenge in the Mouse Model

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Unique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses

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Human 4F5 single-chain Fv antibody recognizing a conserved HA1 epitope has broad neutralizing potency against H5N1 influenza A viruses of different clades

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Fast vaccine design and development based on correlates of protection (COPs): Influenza as a trendsetter

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Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

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Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis

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Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation

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Recombinant influenza A virus hemagglutinin HA2 subunit protects mice against influenza A(H7N9) virus infection

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Influenza Virus–Specific Human Antibody Repertoire Studies

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Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses

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Innate and adaptive immune responses against Influenza A Virus: Immune evasion and vaccination strategies

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Cross-Reactive Fc-Fused Single-Domain Antibodies to Hemagglutinin Stem Region Protect Mice from Group 1 Influenza a Virus Infection

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Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine

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Antibody sequence determinants of viral antigen specificity

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Subcutaneous immunization with recombinant adenovirus expressing influenza A nucleoprotein protects mice against lethal viral challenge

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An Adenovirus-Vectored Influenza Vaccine Induces Durable Cross-Protective Hemagglutinin Stalk Antibody Responses in Mice

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Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin

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Call for a paradigm shift in the design of universal influenza vaccines by harnessing multiple correlates of protection

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Structurally Conserved Binding Sites of Hemagglutinin as Targets for Influenza Drug and Vaccine Development

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Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies

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Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies

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Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens

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The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection

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Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines

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Report on the first WHO integrated meeting on development and clinical trials of influenza vaccines that induce broadly protective and long-lasting immune responses

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Passive Immune Neutralization Strategies for Prevention and Control of Influenza A Infections

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Construction and immunogenicity evaluation of an epitope-based antigen against swine influenza A virus using Escherichia coli heat-labile toxin B subunit as a carrier–adjuvant

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A novel hemagglutinin protein produced in bacteria protects chickens against H5N1 highly pathogenic avian influenza viruses by inducing H5 subtype-specific neutralizing antibodies

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Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage

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Immune responses to infection with H5N1 influenza virus

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Newly Established Monoclonal Antibodies for Immunological Detection of H5N1 Influenza Virus

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HA2 glycopolypeptide of influenza A virus and antiviral immunity

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Structural and antigenic characterization of a computationally-optimized H5 hemagglutinin influenza vaccine

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Population implications of the deployment of novel universal vaccines against epidemic and pandemic influenza

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Inverse folding of protein complexes with a structure-informed language model enables unsupervised antibody evolutionPreprint

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Prospects for broadly protective influenza vaccines

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Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3

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The potential economic value of a ‘universal’ (multi‐year) influenza vaccine

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Localization of epitopes recognized by monoclonal antibodies that neutralized the H3N2 influenza viruses in man

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Universal Flu Vaccines: Primum non nocere

Crowe, J. E. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007118 · Cited by 17

Antiviral Vaccines: Challenges and Advances

Ellebedy, A. H., & Ahmed, R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802174-3.00015-1 · Cited by 19

Lowered pH Leads to Fusion Peptide Release and a Highly Dynamic Intermediate of Influenza Hemagglutinin

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A nanoemulsion-adjuvanted intranasal H5N1 influenza vaccine protects ferrets against homologous and heterologous H5N1 lethal challenge

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Prospects for antibody-based universal influenza vaccines in the context of widespread pre-existing immunity

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B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant

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Bringing influenza vaccines into the 21st century

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Determination of serum neutralization antibodies against seasonal influenza A strain H3N2 and the emerging strains 2009 H1N1 and avian H5N1

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Structural Insights into the Membrane Fusion Mechanism Mediated by Influenza Virus Hemagglutinin

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A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza

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Cross-protection against homo and heterologous influenza viruses via intranasal administration of an HA chimeric multiepitope nanoparticle vaccine

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De novo design of epitope-specific antibodies via a structure-driven computational workflow

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McMillan, C. L. D., Cheung, S. T. M., Modhiran, N., Barnes, J., Amarilla, A. A., Bielefeldt‐Ohmann, H., Lee, L., Guilfoyle, K. A., van Amerongen, G., Stittelaar, K. J., et al. (2021) · npj Vaccines · doi:10.1038/s41541-021-00395-4 · Cited by 16

Stereotyped B‐cell responses are linked to IgG constant region polymorphisms in multiple sclerosis

Lindeman, I., Polak, J., Qiao, S., Holmøy, T., Høglund, R. A., Vartdal, F., Berg‐Hansen, P., Sollid, L. M., & Lossius, A. (2022) · European Journal of Immunology · doi:10.1002/eji.202149576 · Cited by 16

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Yang, R. S., Traver, M. K., Barefoot, N. Z., Stephens, T., Alabanza, C., Manzella‐Lapeira, J., Zou, G., Wolff, J. J., Li, Y., Resto, M., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-54876-2 · Cited by 16

DNA Prime and Virus-like Particle Boost From a Single H5N1 Strain Elicits Broadly Neutralizing Antibody Responses Against Head Region of H5 Hemagglutinin

Wang, G., Zhou, F., Buchy, P., Zuo, T., Hu, H., Liu, J., Song, Y., Ding, H., Tsai, C., Chen, Z., et al. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit414 · Cited by 16

Influenza virus hemagglutinin as a vaccine antigen produced in bacteria.

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8thAnnual European Antibody Congress 2012

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Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors

Tang, G., Qiu, Z., Lin, X., Li, W., Zhu, L., Li, S., Li, H., Wang, L., Chen, L., Wu, J. Z., et al. (2010) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2010.04.141 · Cited by 16

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Human monoclonal antibodies as candidate therapeutics against emerging viruses and HIV-1

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Contribution of Light Chain Residues to High Affinity Binding in an HIV-1 Antibody Explored by Combinatorial Scanning Mutagenesis

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Human protective monoclonal antibodies against the HA stem of group 2 HAs derived from an H3N2 virus-infected human

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Filamentous anti-influenza agents wrapping around viruses

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Baas, D. C., Koopmans, M., de Bruin, E., ten Hulscher, H. I., Buisman, A. M., Hendrikx, L. H., van Beek, J., Godeke, G.-J., Reimerink, J. H. J., & van Binnendijk, R. S. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23535 · Cited by 15

In Silico Structural Homology Modelling and Docking for Assessment of Pandemic Potential of a Novel H7N9 Influenza Virus and Its Ability to Be Neutralized by Existing Anti-Hemagglutinin Antibodies

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Antigenic Characterization of Recombinant Hemagglutinin Proteins Derived from Different Avian Influenza Virus Subtypes

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Research highlights

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A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

Ekiert, D. C., Friesen, R. H. E., Bhabha, G., Kwaks, T., Jongeneelen, M. A. C., Yu, W., Ophorst, C., Cox, F., Korse, H. J. W. M., Brandenburg, B., et al. (2011) · Science · doi:10.1126/science.1204839 · Cited by 820

A Virus-Like Particle That Elicits Cross-Reactive Antibodies to the Conserved Stem of Influenza Virus Hemagglutinin

(2016)

An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells

Lee, C., Yang, C.-Y., Lin, L., Ko, T., Chang, A., Chang, S. S.-C., & Wang, A. H. ‐. (2019) · Scientific Reports · doi:10.1038/s41598-019-40937-4 · Cited by 22