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The Dynamic Architecture of Hox Gene Clusters
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Sequential activation of Hox genes correlates with a transition of negative to positive three-dimensional chromosome structure.
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Citations
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“…are proposed to define domains of long-range interaction that tie distant enhancer regions to Hox genes, within specific TAD domains, and thereby determine the activation of these genes in a spatially appropriate manner (Andrey et al., 2013; Darbellay and Duboule, 2016; Noordermeer et al., 2011).”
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Self-citationConvergent evolution of complex regulatory landscapes and pleiotropy at Hox loci
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Metadata
- Authors
- Noordermeer, D., Leleu, M., Splinter, E., Rougemont, J., De Laat, W., & Duboule, D.
- Venue
- Science
- Published
- 2011-10-14
- Volume
- 334
- Issue
- 6053
- Pages
- 222-225
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2169236261
- Cited by
- 391
- References
- 4
- FWCI
- 15.40
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.