Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

Stroke rehabilitation

Langhorne, P., Bernhardt, J., & Kwakkel, G. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60325-5 · Cited by 2,726

Plasticity during stroke recovery: from synapse to behaviour

Murphy, T. H., & Corbett, D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2735 · Cited by 1,938

Recommendations for Standards Regarding Preclinical Neuroprotective and Restorative Drug Development

Roundtable, S. T. A. I. (1999) · Stroke · doi:10.1161/01.str.30.12.2752 · Cited by 1,256

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

Alexander, G. M., Rogan, S. C., Abbas, A. I., Armbruster, B. N., Pei, Y., Allen, J., Nonneman, R. J., Hartmann, J. F., Moy, S. S., Nicolelis, M. A. L., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.014 · Cited by 1,019

Neuroplasticity in the context of motor rehabilitation after stroke

Dimyan, M. A., & Cohen, L. G. (2011) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.200 · Cited by 732

The “staircase test”: a measure of independent forelimb reaching and grasping abilities in rats

Montoya, C. P., Campbell-Hope, L. J., Pemberton, K. D., & Dunnett, S. B. (1991) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(91)90048-5 · Cited by 610

Cellular and molecular mechanisms of neural repair after stroke: making waves

Carmichael, S. T. (2006) · Annals of Neurology · doi:10.1002/ana.20845 · Cited by 595

Getting Neurorehabilitation Right: What Can Be Learned From Animal Models?

Krakauer, J. W., Carmichael, S. T., Corbett, D., & Wittenberg, G. F. (2012) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968312440745 · Cited by 591

Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation

García‐Alías, G., Barkhuysen, S., Buckle, M., & Fawcett, J. W. (2009) · Nature Neuroscience · doi:10.1038/nn.2377 · Cited by 474

The interaction between training and plasticity in the poststroke brain

Zeiler, S. R., & Krakauer, J. W. (2013) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000025 · Cited by 436

Dissecting the Tectal Output Channels for Orienting and Defense Responses

Isa, K., Sooksawate, T., Kobayashi, K., Kobayashi, K., Redgrave, P., & Isa, T. (2020) · eNeuro · doi:10.1523/eneuro.0271-20.2020 · Cited by 49

Coordinated Plasticity of Synapses and Astrocytes Underlies Practice-Driven Functional Vicariation in Peri-Infarct Motor Cortex

Kim, S. Y., Hsu, J. E., Husbands, L. C., Kleim, J. A., & Jones, T. A. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.1295-17.2017 · Cited by 48

Enhancing Spinal Plasticity Amplifies the Benefits of Rehabilitative Training and Improves Recovery from Stroke

Wiersma, A. M., Fouad, K., & Winship, I. R. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0770-17.2017 · Cited by 44

Refueling the Ischemic CNS: Guidance Molecules for Vascular Repair

Rust, R., Grönnert, L., Weber, R., Mulders, G., & Schwab, M. E. (2019) · Trends in Neurosciences · doi:10.1016/j.tins.2019.05.006 · Cited by 44

Lesion Size- and Location-Dependent Recruitment of Contralesional Thalamus and Motor Cortex Facilitates Recovery after Stroke in Mice

Aswendt, M., Pallast, N., Wieters, F., Baues, M., Hoehn, M., & Fink, G. R. (2020) · Translational Stroke Research · doi:10.1007/s12975-020-00802-3 · Cited by 44

Neuronal activity-dependent myelin repair after stroke

Jia, W., Kamen, Y., Pivoňková, H., & Káradóttir, R. T. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.03.005 · Cited by 45

Brain stimulation: Neuromodulation as a potential treatment for motor recovery following traumatic brain injury

Clayton, E. C., Kinley-Cooper, S. K., Weber, R. A., & Adkins, D. L. (2016) · Brain Research · doi:10.1016/j.brainres.2016.01.056 · Cited by 41

The Spinal Transcriptome after Cortical Stroke: In Search of Molecular Factors Regulating Spontaneous Recovery in the Spinal Cord

Kaiser, J., Maibach, M. A., Salpeter, I., Hagenbuch, N., de Souza, V. B. C., Robinson, M. D., & Schwab, M. E. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2571-18.2019 · Cited by 40

Toward Functional Restoration of the Central Nervous System: A Review of Translational Neuroscience Principles

Krucoff, M. O., Miller, J. P., Saxena, T. K., Bellamkonda, R., Rahimpour, S., Harward, S. C., Lad, S. P., & Turner, D. A. (2018) · Neurosurgery · doi:10.1093/neuros/nyy128 · Cited by 38

Direct, long-term intrathecal application of therapeutics to the rodent CNS

Ineichen, B. V., Schnell, L., Gullo, M., Kaiser, J., Schneider, M. P., Mosberger, A. C., Good, N., Linnebank, M., & Schwab, M. E. (2016) · Nature Protocols · doi:10.1038/nprot.2016.151 · Cited by 37

Nogo-A Antibodies for Progressive Multiple Sclerosis

Ineichen, B. V., Plattner, P. S., Good, N., Martinꝉ, R., Linnebank, M., & Schwab, M. E. (2017) · CNS Drugs · doi:10.1007/s40263-017-0407-2 · Cited by 37

Attractive and repulsive factors act through multi-subunit receptor complexes to regulate nerve fiber growth

Thiede-Stan, N. K., & Schwab, M. E. (2015) · Journal of Cell Science · doi:10.1242/jcs.165555 · Cited by 37

Now is the Critical Time for Engineered Neuroplasticity

Moritz, C. T. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0637-0 · Cited by 37

Neural repair mechanisms after ischemic stroke

Irisa, K., & Shichita, T. (2025) · Inflammation and Regeneration · doi:10.1186/s41232-025-00372-7 · Cited by 35

Corticospinal circuit plasticity in motor rehabilitation from spinal cord injury

Serradj, N., Agger, S., & Hollis, E. R., II (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.12.003 · Cited by 37

Ischemic Stroke in Pontine and Corona Radiata: Location Specific Impairment of Neural Network Investigated With Resting State fMRI

Jiang, C., Yi, L., Cai, S., & Zhang, L. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00575 · Cited by 35

Recovery After Stroke

Cramer, S. C. (2020) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000838 · Cited by 38

The effect of combined therapies on recovery after acquired brain injury: Systematic review of preclinical studies combining enriched environment, exercise, or task-specific training with other therapies

Rytter, H. M., & Rasmussen, C. P. (2016) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-160682 · Cited by 35

Future of Animal Modeling for Poststroke Tissue Repair

Modo, M., Jolkkonen, J., Zille, M., & Boltze, J. (2018) · Stroke · doi:10.1161/strokeaha.117.018293 · Cited by 35

Parvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug

Okabe, N., Wei, X., Abumeri, F., Batac, J., Hovanesyan, M., Dai, W., Azarapetian, S., Campagna, J. J., Pilati, N., Marasco, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57860-0 · Cited by 34

Evaluating the effectiveness of anti-Nogo treatment in spinal cord injuries

Mohammed, R., Opara, K., Lall, R., Ojha, U., & Xiang, J. (2020) · Neural Development · doi:10.1186/s13064-020-0138-9 · Cited by 34

Self-modulation of motor cortex activity after stroke: a randomized controlled trial

Sanders, Z., Fleming, M. K., Smejka, T., Marzolla, M. C., Zich, C., Rieger, S. W., Lührs, M., Goebel, R., Sampaio‐Baptista, C., & Johansen‐Berg, H. (2022) · Brain · doi:10.1093/brain/awac239 · Cited by 33

Spinal cord associative plasticity improves forelimb sensorimotor function after cervical injury

Pal, A., Park, H., Ramamurthy, A., Asan, A. S., Bethea, T., Johnkutty, M., & Carmel, J. B. (2022) · Brain · doi:10.1093/brain/awac235 · Cited by 32

Capacity of astrocytes to promote axon growth in the injured mammalian central nervous system

Hemati-Gourabi, M., Cao, T., Romprey, M. K., & Chen, M. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.955598 · Cited by 32

Nafamostat Mesilate Improves Neurological Outcome and Axonal Regeneration after Stroke in Rats

Liu, Y., Li, C., Wang, J., Fang, Y., Sun, H., Tao, X., Zhou, X., & Liao, H. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9999-7 · Cited by 31

FreiPose: A Deep Learning Framework for Precise Animal Motion Capture in 3D SpacesPreprint

Zimmermann, C., Schneider, A., Alyahyay, M., Brox, T., & Diester, I. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.27.967620 · Cited by 33

Knock down of lncRNA H19 promotes axon sprouting and functional recovery after cerebral ischemic stroke

Hu, S., Zheng, J., Du, Z., & Wu, G. (2020) · Brain Research · doi:10.1016/j.brainres.2020.146681 · Cited by 30

Axonal remodeling in the corticospinal tract after stroke: how does rehabilitative training modulate it?

Okabe, N., Narita, K., & Miyamoto, O. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.200792 · Cited by 30

Fostering Poststroke Recovery

Sommer, C., & Schäbitz, W. (2017) · Stroke · doi:10.1161/strokeaha.116.013324 · Cited by 29

Motor Cortex Maturation Is Associated with Reductions in Recurrent Connectivity among Functional Subpopulations and Increases in Intrinsic Excitability

Biane, J. S., Scanziani, M., Tuszynski, M. H., & Conner, J. M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2792-14.2015 · Cited by 32

Compensatory Relearning Following Stroke: Cellular and Plasticity Mechanisms in Rodents

Balbinot, G. C., & Schuch, C. P. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.01023 · Cited by 30

Constraint induced movement therapy promotes contralesional-oriented structural and bihemispheric functional neuroplasticity after stroke

Liu, P., Li, C., Zhang, B., Zhang, Z., Gao, B., Liu, Y., Wang, Y., Yan, H., Hu, J., Qiu, X., et al. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.06.003 · Cited by 29

HDAC2 (Histone deacetylase 2): A critical factor in environmental enrichment‐mediated stroke recovery

Lin, Y., Yao, M., Wu, H., Dong, J. P., Ni, H., Kou, X., Chang, L., Luo, C., & Zhu, D. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15043 · Cited by 29

A motorized pellet dispenser to deliver high intensity training of the single pellet reaching and grasping task in rats

Espin, A. T., Forero, J. P., Schmidt, E. K. A., Fouad, K., & Fenrich, K. K. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.08.033 · Cited by 28

Anti-Nogo-A Antibodies As a Potential Causal Therapy for Lower Urinary Tract Dysfunction after Spinal Cord Injury

Schneider, M. P., Sartori, A. M., Ineichen, B. V., Moors, S., Engmann, A. K., Hofer, A., Weinmann, O., Kessler, T. M., & Schwab, M. E. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.3155-18.2019 · Cited by 28

The tracts, cytoarchitecture, and neurochemistry of the spinal cord

Tan, S., Faull, R. L. M., & Curtis, M. A. (2022) · The Anatomical Record · doi:10.1002/ar.25079 · Cited by 35

Epothilones Improve Axonal Growth and Motor Outcomes after Stroke in the Adult Mammalian CNS

Kugler, C., Thielscher, C., Tambe, B. A., Schwarz, M. K., Halle, A., Bradke, F., & Petzold, G. C. (2020) · Cell Reports Medicine · doi:10.1016/j.xcrm.2020.100159 · Cited by 28

Rehabilitative skilled forelimb training enhances axonal remodeling in the corticospinal pathway but not the brainstem-spinal pathways after photothrombotic stroke in the primary motor cortex

Okabe, N., Himi, N., Nakamura‐Maruyama, E., Hayashi, N., Narita, K., & Miyamoto, O. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187413 · Cited by 27

Power spectrum slope is related to motor function after focal cerebral ischemia in the rat

Leemburg, S., Gao, B., Cam, E., Sarnthein, J., & Bassetti, C. L. (2018) · SLEEP · doi:10.1093/sleep/zsy132 · Cited by 29

Mechanisms and significance of microglia–axon interactions in physiological and pathophysiological conditions

Fujita, Y., & Yamashita, T. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03758-1 · Cited by 30

Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury

Nakamura, Y., Ueno, M., Niehaus, J. K., Lang, R. A., Zheng, Y., & Yoshida, Y. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2649-20.2021 · Cited by 26

Selective Manipulation of Neural Circuits

Park, H. G., & Carmel, J. B. (2016) · Neurotherapeutics · doi:10.1007/s13311-016-0425-7 · Cited by 29

Axotomized Corticospinal Neurons Increase Supra-Lesional Innervation and Remain Crucial for Skilled Reaching after Bilateral Pyramidotomy

Mosberger, A. C., Miehlbradt, J., Bjelopoljak, N., Schneider, M. P., Wahl, A.-S., Ineichen, B. V., Gullo, M., & Schwab, M. E. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw405 · Cited by 25

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

Quattromani, M. J., Hakon, J., Rauch, U., Bauer, A. Q., & Wieloch, T. W. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.01.011 · Cited by 25

Principles and requirements for stroke recovery science

Sommer, C., & Schäbitz, W. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x20970048 · Cited by 25

Crossing nerve transfer drives sensory input–dependent plasticity for motor recovery after brain injury

Gao, Z., Pang, Z., Lei, G., Chen, Y., Cai, Z., Zhu, S., Lin, W., Qiu, Z., Wang, Y., Shen, Y., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn5899 · Cited by 28

Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity

Hakon, J., Quattromani, M. J., Sjölund, C., Talhada, D., Kim, B., Moyanova, S. G., Mastroiacovo, F., Menna, L. D., Olsson, R., Englund, E. M., et al. (2023) · Brain · doi:10.1093/brain/awad293 · Cited by 25

Delayed exposure to environmental enrichment improves functional outcome after stroke

Tang, Y., Li, M.-Y., Zhang, X., Jin, X., Liu, J., & Wei, P. (2019) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2019.05.002 · Cited by 25

Regenerative Rehabilitation for Stroke Recovery by Inducing Synergistic Effects of Cell Therapy and Neurorehabilitation on Motor Function: A Narrative Review of Pre-Clinical Studies

Ito, A., Kubo, N., Liang, N., Aoyama, T., & Kuroki, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093135 · Cited by 25

Targeting Therapeutic Antibodies to the CNS: a Comparative Study of Intrathecal, Intravenous, and Subcutaneous Anti-Nogo A Antibody Treatment after Stroke in Rats

Wahl, A.-S., Correa, D., Imobersteg, S., Maurer, M., Kaiser, J., Augath, M. A., & Schwab, M. E. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00864-z · Cited by 23

Brain-wide neural dynamics of poststroke recovery induced by optogenetic stimulation

Vahdat, S., Pendharkar, A. V., Chiang, T., Harvey, S. S., 内野晴登, Cao, Z., Kim, A. Y., Choy, M., Chen, H., Lee, H. J., et al. (2021) · Science Advances · doi:10.1126/sciadv.abd9465 · Cited by 23

Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling

Lin, Y., Yang, D., Ni, H., Xu, X.-M., Wu, F., Lin, L., Chen, J., Sun, Y. H., Huang, Z., Li, S., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112294 · Cited by 24

Exercise Training Inhibits the Nogo-A/NgR1/Rho-A Signals in the Cortical Peri-infarct Area in Hypertensive Stroke Rats

Li, C., Wen, H., Wang, Q., Zhang, C., Jiang, L., Dou, Z., Luo, X., & Zeng, J. (2015) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000339 · Cited by 23

Optogenetic Stimulation Enhanced Neuronal Plasticities in Motor Recovery after Ischemic Stroke

Lu, C., Wu, X., Ma, H., Wang, Q., Wang, Y., Luo, Y., Li, C., & Xu, H. (2019) · Neural Plasticity · doi:10.1155/2019/5271573 · Cited by 24

Cell-to-Cell Interactions Mediating Functional Recovery after Stroke

Alia, C., Cangi, D., Massa, V., Salluzzo, M., Vignozzi, L., Caleo, M., & Spalletti, C. (2021) · Cells · doi:10.3390/cells10113050 · Cited by 24

Harnessing cortical plasticity via gabapentinoid administration promotes recovery after stroke

Tedeschi, A., Larson, M. J. E., Zouridakis, A., Mo, L., Bordbar, A., Myers, J. M., Qin, H. Y., Rodocker, H. I., Fan, F., Lannutti, J. J., et al. (2022) · Brain · doi:10.1093/brain/awac103 · Cited by 24

Sox9 knockout mice have improved recovery following stroke

Xu, X., Bass, B. R. L., McKillop, W. M., Mailloux, J., Liu, T., Geremia, N. M., Hryciw, T., & Brown, A. M. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.02.001 · Cited by 23

Motivational state, reward value, and Pavlovian cues differentially affect skilled forelimb grasping in ratsPreprint

Mosberger, A. C., de Clauser, L., Kasper, H., & Schwab, M. E. (2016) · Learning & Memory · doi:10.1101/lm.039537.115 · Cited by 25

Effect of Stroke on Contralateral Functional Connectivity

Yourganov, G., Stark, B. C., Fridriksson, J., Bonilha, L., & Rorden, C. (2021) · Brain Connectivity · doi:10.1089/brain.2020.0901 · Cited by 22

Electroacupuncture Activates Neuroplasticity in the Motor Cortex and Corticospinal Tract via the mTOR Pathway in a Rat P‐MCAO Model

Zhang, Y., Yin, Y.-L., Jin, Z., Hu, Q., & Wu, X. (2022) · BioMed Research International · doi:10.1155/2022/3470685 · Cited by 22

Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex

Thiede-Stan, N. K., Tews, B., Albrecht, D., Ristic, Z., Ewers, H., & Schwab, M. E. (2015) · Journal of Cell Science · doi:10.1242/jcs.167981 · Cited by 22

A data-driven approach for evaluating multi-modal therapy in traumatic brain injury

Haefeli, J., Ferguson, A. R., Bingham, D., Orr, A., Won, S. J., Lam, T. I., Shi, J., Hawley, S., Liu, J., Swanson, R. A., et al. (2017) · Scientific Reports · doi:10.1038/srep42474 · Cited by 23

Recovery after spinal cord injury is enhanced by anti-Nogo-A antibody therapy — from animal models to clinical trials

Sartori, A. M., Hofer, A., & Schwab, M. E. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.11.001 · Cited by 22

Unsupervised behaviour analysis and magnification (uBAM) using deep learning

Brattoli, B., Büchler, U., Dorkenwald, M., Reiser, P., Filli, L., Helmchen, F., Wahl, A.-S., & Ommer, B. (2021) · Nature Machine Intelligence · doi:10.1038/s42256-021-00326-x · Cited by 22

Restoration of spinal cord injury: From endogenous repairing process to cellular therapy

Wu, Y., Tang, Z., Zhang, J., Wang, Y., & Liu, S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1077441 · Cited by 21

Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity-Dependent Stimulation

Moritz, C. T., & Ambrosio, F. (2017) · Pediatric Physical Therapy · doi:10.1097/pep.0000000000000378 · Cited by 21

PTEN Blocking Stimulates Corticospinal and Raphespinal Axonal Regeneration and Promotes Functional Recovery After Spinal Cord Injury

Bhowmick, S., & Muneer, P. M. A. (2020) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlaa147 · Cited by 21

The diversity and plasticity of descending motor pathways rewired after stroke and trauma in rodents

Inoue, T., & Ueno, M. (2025) · Frontiers in Neural Circuits · doi:10.3389/fncir.2025.1566562 · Cited by 21

3D pose estimation enables virtual head fixation in freely moving rats

Schneider, A., Zimmermann, C., Alyahyay, M., Steenbergen, F., Brox, T., & Diester, I. (2022) · Neuron · doi:10.1016/j.neuron.2022.04.019 · Cited by 20

Genetic manipulation of specific neural circuits by use of a viral vector system

Kobayashi, K., Kato, S., & Kobayashi, K. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-016-1674-7 · Cited by 20

Cerebral imaging of post-stroke plasticity and tissue repair

Loubinoux, I., Brihmat, N., Castel-Lacanal, E., & Marqué, P. (2017) · Revue Neurologique · doi:10.1016/j.neurol.2017.09.007 · Cited by 25

Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury

Griffin, J. M., Hingorani Jai Prakash, S., Bockemühl, T., Benner, J. M., Schaffran, B., Moreno-Manzano, V., Büschges, A., & Bradke, F. (2022) · Brain Communications · doi:10.1093/braincomms/fcad005 · Cited by 19

Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury

Meves, J. M., Geoffroy, C. G., Kim, N. D., Kim, J. J., & Zheng, B. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.07.013 · Cited by 19

Dual motor cortex and spinal cord neuromodulation improves rehabilitation efficacy and restores skilled locomotor function in a rat cervical contusion injury model

Sharif, H., Alexander, H., Azam, A., & Martin, J. H. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113715 · Cited by 21

Rehabilitative training paired with peripheral stimulation promotes motor recovery after ischemic cerebral stroke

Hu, S., Wu, G., Wu, B., Du, Z., & Zhang, Y. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113960 · Cited by 18

Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy

Panos, L. D., Bargiotas, P., Arnold, M., Hadjigeorgiou, G. M., & Panos, G. D. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s460998 · Cited by 18

Constraint-induced movement therapy improves efficacy of task-specific training after severe cortical stroke depending on the ipsilesional corticospinal projections

Okabe, N., Himi, N., Nakamura‐Maruyama, E., Hayashi, N., Sakamoto, I., Narita, K., Hasegawa, T., & Miyamoto, O. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.04.006 · Cited by 18

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats

Wen, T., Lall, S., Pagnotta, C., Markward, J., Gupta, D., Ratnadurai‐Giridharan, S., Bucci, J., Greenwald, L. M., Klugman, M. F., Hill, N. J., et al. (2018) · Frontiers in Neural Circuits · doi:10.3389/fncir.2018.00028 · Cited by 20

Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion

Barios, J. A., Pisarchyk, L., Fernandez-Garcia, L., Barrio, L. C., Ramos, M., Martínez‐Murillo, R., & González‐Nieto, D. (2015) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x15606139 · Cited by 18

Improved functional outcome after chronic stroke with delayed anti-Nogo-A therapy: A clinically relevant intention-to-treat analysis

Podraza, K. M., Mehta, Y., Husak, V. A., Lippmann, E., O’Brien, T. E., Kartje, G. L., & Tsai, S. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17730994 · Cited by 18

Biomaterials for Stroke Therapy

Love, C. J., Selim, M. H., Spector, M., & Lo, E. H. (2019) · Stroke · doi:10.1161/strokeaha.118.023721 · Cited by 18

Focal Stroke in the Developing Rat Motor Cortex Induces Age- and Experience-Dependent Maladaptive Plasticity of Corticospinal System

Gennaro, M., Mattiello, A., Mazziotti, R. M., Antonelli, C., Gherardini, L. M., Guzzetta, A., Berardi, N., Cioni, G., & Pizzorusso, T. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00047 · Cited by 18

Early reduced behavioral activity induced by large strokes affects the efficiency of enriched environment in rats

Wahl, A.-S., Erlebach, E., Brattoli, B., Büchler, U., Kaiser, J., Ineichen, B. V., Mosberger, A. C., Schneeberger, S., Imobersteg, S., Wieckhorst, M., et al. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x18777661 · Cited by 17

Combining task-based rehabilitative training with PTEN inhibition promotes axon regeneration and upper extremity skilled motor function recovery after cervical spinal cord injury in adult mice

Pan, L., Tan, B., Tang, W., Luo, M., Liu, Y., Yu, L., & Yin, Y. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113197 · Cited by 18

No evidence for motor-recovery-related cortical connectivity changes after stroke using resting-state fMRI

Branscheidt, M., Ejaz, N., Xu, J., Widmer, M., Harran, M. D., Cortés, J. C., Kitago, T., Celnik, P. A., Hernandez-Castillo, C. R., Diedrichsen, J., et al. (2021) · Journal of Neurophysiology · doi:10.1152/jn.00148.2021 · Cited by 20

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Nandakumar, B., Blumenthal, G. H., Pauzin, F. P., & Moxon, K. A. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab150 · Cited by 16

Urodynamic measurements reflect physiological bladder function in rats

Schneider, M. P., Sartori, A. M., Tampé, J., Moors, S., Engmann, A. K., Ineichen, B. V., Hofer, A., Schwab, M. E., & Kessler, T. M. (2017) · Neurourology and Urodynamics · doi:10.1002/nau.23455 · Cited by 16

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Zhu, X., Ai, Z., Hu, X., & Li, T. (2016) · Scientific Reports · doi:10.1038/srep28572 · Cited by 16

Optogenetic modulation in stroke recovery

Pendharkar, A. V., Levy, S. L., Ho, A. L., Sussman, E. S., Cheng, M., & Steinberg, G. K. (2016) · Neurosurgical FOCUS · doi:10.3171/2016.2.focus163 · Cited by 16

Nogo-A Regulates the Fate of Human Dental Pulp Stem Cells toward Osteogenic, Adipogenic, and Neurogenic Differentiation

Lai, C. F., Shen, J., Balic, A., Pagella, P., Schwab, M. E., & Mitsiadis, T. A. (2022) · Cells · doi:10.3390/cells11213415 · Cited by 14

Anti-repulsive guidance molecule-a antibody treatment and repetitive transcranial magnetic stimulation have synergistic effects on motor recovery after spinal cord injury

Nakanishi, T., Fujita, Y., Tanaka, T., & Yamashita, T. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134329 · Cited by 14

Environmental enrichment during the chronic phase after experimental stroke promotes functional recovery without synergistic effects of EphA4 targeted therapy

de Boer, A., Storm, A., Gómez‐Soler, M., Smolders, S., Rué, L., Poppe, L., Pasquale, E. B., Robberecht, W., & Lemmens, R. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz288 · Cited by 14

Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires repeated handling

Gómez‐Gálvez, Y., Gupta, M., Kaur, M., Fusco, S., Podda, M. V., Grassi, C., Srivastava, A. K., Iacovitti, L., & Blanco‐Suárez, E. (2024) · PLoS ONE · doi:10.1371/journal.pone.0312298 · Cited by 13

Nogo‐A inhibits vascular regeneration in ischemic retinopathy

Joly, S., Dejda, A., Rodriguez, L., Sapieha, P. S., & Pernet, V. (2018) · Glia · doi:10.1002/glia.23462 · Cited by 13

Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 months

Krucoff, M. O., Gramer, R., Lott, D., Kale, E. B., Yadav, A. P., Abd‐El‐Barr, M. M., Sinha, S. R., & Lad, S. P. (2020) · Spinal Cord Series and Cases · doi:10.1038/s41394-020-00345-7 · Cited by 13

Automation of training and testing motor and related tasks in pre-clinical behavioural and rehabilitative neuroscience

Mah, K. M., Espin, A. T., Hallworth, B. W., Bixby, J. L., Lemmon, V., Fouad, K., & Fenrich, K. K. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113647 · Cited by 13

LZK-dependent stimulation of astrocyte reactivity promotes corticospinal axon sprouting

Chen, M., Ingle, L., Plautz, E. J., Kong, X., Tang, R., Ghosh, N., Romprey, M. K., Fenske, W. K., & Goldberg, M. P. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.969261 · Cited by 13

Clinical Application of Robotics and Technology in the Restoration of Walking

Esquenazi, A., Maier, I. C., Aurich-Schuler, T., Beer, S. M., Borggraefe, I., Campen, K., Luft, A. R., Manoglou, D., Meyer‐Heim, A., Spiess, M. R., et al. (2016) · Springer eBooks · doi:10.1007/978-3-319-28603-7_12 · Cited by 13

Correlates of Post-Stroke Brain Plasticity, Relationship to Pathophysiological Settings and Implications for Human Proof-of-Concept Studies

Sánchez-Mendoza, E. H., & Hermann, D. M. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00196 · Cited by 13

Contralesional Sensorimotor Network Participates in Motor Functional Compensation in Glioma Patients

Fang, S., Li, L., Weng, S., Guo, Y., Zhong, Z., Fan, X., Jiang, T., & Wang, Y. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.882313 · Cited by 12

Neuronal repair. Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

Wahl, A. S., Omlor, W., Rubio, J. C., Chen, J. L., Zheng, H., Schroeter, A., Gullo, M., Weinmann, O., Kobayashi, K., Helmchen, F., et al. (2014) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-107011 · Cited by 1

Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation

Wahl, A.-S., Büchler, U., Brändli, A., Brattoli, B., Musall, S., Kasper, H., Ineichen, B. V., Helmchen, F., Ommer, B., & Schwab, M. E. (2017) · Nature Communications · doi:10.1038/s41467-017-01090-6 · Cited by 79

Timing is everything for Nogo-specific antibodies

Cully, M. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4397

Rejuvenation of corticospinal neurons enhances rehabilitation-associated corticospinal tract axon sprouting and functional recovery post photothrombotic ischemic stroke in mice

Sun, B., Sun, L., Zhang, L., Xue, X., Tian, Q., Wu, L., Li, M., Huang, J., Ni, H., Xu, L., et al. (2025) · Genes & Diseases · doi:10.1016/j.gendis.2025.102000

Rewiring of the corticospinal tract in the adult rat after unilateral stroke and anti-Nogo-A therapy

Lindau, N. T., Bänninger, B. J., Gullo, M., Good, N., Bachmann, L. C., Starkey, M. L., & Schwab, M. E. (2013) · Brain · doi:10.1093/brain/awt336 · Cited by 178