Cited by 322Stroke Rehabilitation and RecoveryNerve injury and regenerationSpinal Cord Injury Research

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

Wahl, A. S., Omlor, W., Rubio, J. C., Chen, J. L., Zheng, H., Schröter, A., Gullo, M., Weinmann, O., Kobayashi, K., Helmchen, F., Ommer, B., Schwab, M. E.·2014·Science

DOI 10.1126/science.1253050

Open this paper in CoChat — free account

Abstract

Improving stroke recovery by timing treatment: Patients recovering from strokes often fight a long uphill battle, with mixed results. Studying the effect of physical training on regeneration from damaged nerves in a model of stroke in rats, Wahl et al. show that timing matters. First, the researchers gave the rats a stroke, which damaged their ability to reach for food pellets with their forelimbs. The researchers then gave them physical training and treated them with an antibody to encourage neural regeneration. The rats improved more when the researchers waited until after the antibody treatment to start the training. Damaged circuits, it seems, need a little time to regrow before being called into action. Science , this issue p. 1250

Integrity signals

Registry

Crossref · 10.1126/science.1253050

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Stroke rehabilitation
Langhorne, P., Bernhardt, J., & Kwakkel, G. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60325-5 · Cited by 2,726
Plasticity during stroke recovery: from synapse to behaviour
Murphy, T. H., & Corbett, D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2735 · Cited by 1,938
Recommendations for Standards Regarding Preclinical Neuroprotective and Restorative Drug Development
Roundtable, S. T. A. I. (1999) · Stroke · doi:10.1161/01.str.30.12.2752 · Cited by 1,256
Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors
Alexander, G. M., Rogan, S. C., Abbas, A. I., Armbruster, B. N., Pei, Y., Allen, J., Nonneman, R. J., Hartmann, J. F., Moy, S. S., Nicolelis, M. A. L., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.014 · Cited by 1,019
Neuroplasticity in the context of motor rehabilitation after stroke
Dimyan, M. A., & Cohen, L. G. (2011) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.200 · Cited by 732
The “staircase test”: a measure of independent forelimb reaching and grasping abilities in rats
Montoya, C. P., Campbell-Hope, L. J., Pemberton, K. D., & Dunnett, S. B. (1991) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(91)90048-5 · Cited by 610
Cellular and molecular mechanisms of neural repair after stroke: making waves
Carmichael, S. T. (2006) · Annals of Neurology · doi:10.1002/ana.20845 · Cited by 595
Getting Neurorehabilitation Right: What Can Be Learned From Animal Models?
Krakauer, J. W., Carmichael, S. T., Corbett, D., & Wittenberg, G. F. (2012) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968312440745 · Cited by 591
Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation
García‐Alías, G., Barkhuysen, S., Buckle, M., & Fawcett, J. W. (2009) · Nature Neuroscience · doi:10.1038/nn.2377 · Cited by 474
The interaction between training and plasticity in the poststroke brain
Zeiler, S. R., & Krakauer, J. W. (2013) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000025 · Cited by 436

Show all 34 references

Sorted by citations

Items 201–300 of 319

Visualizing advances in the future of primate neuroscience research
Janssen, P., Isa, T., Lanciego, J. L., Leech, K., Logothetis, N. K., Poo, M., & Mitchell, A. S. (2022) · Current Research in Neurobiology · doi:10.1016/j.crneur.2022.100064 · Cited by 12
Improved Functional Outcome After Peripheral Nerve Stimulation of the Impaired Forelimb Post-stroke
Tsai, S., Schreiber, J. A., Adamczyk, N. S., Wu, J. Y., Ton, S. T., Hofler, R. C., Walter, J. S., O’Brien, T. E., Kartje, G. L., & Nockels, R. P. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.610434 · Cited by 12
Plasticity-rigidity cycles: A general adaptation mechanismPreprint
Csermely, P. (2015) · arXiv (Cornell University) · doi:10.48550/arxiv.1511.01239 · Cited by 14
Orosomucoid 2 is an endogenous regulator of neuronal mitochondrial biogenesis and promotes functional recovery post-stroke
Jing, K., Gu, R., Chen, F., Wan, J., Sun, Y., Guo, P., Chen, F., Feng, J., Guo, J., & Liu, X. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107422 · Cited by 11
Effects of Repetitive Transcranial Magnetic Stimulation on Upper and Lower Limb Motor Function and Spasticity After Stroke: A Meta-Analysis
Lee, H. Y., & Ryu, B.-J. (2025) · Brain & Neurorehabilitation · doi:10.12786/bn.2025.18.e5 · Cited by 11
Learning and Stroke Recovery: Parallelism of Biological Substrates
Joy, M. T., & Carmichael, S. T. (2021) · Seminars in Neurology · doi:10.1055/s-0041-1725136 · Cited by 12
The Subventricular Zone Response to Stroke Is Not a Therapeutic Target of Anti-Nogo-A Immunotherapy
Shepherd, D. J., Tsai, S., Cappucci, S. P., Wu, J. Y., Farrer, R. G., & Kartje, G. L. (2017) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlx050 · Cited by 11
Defining mechanisms of neural plasticity after brainstem ischemia in rats
Minnerup, J., Strecker, J., Wachsmuth, L., Hoppen, M., Schmidt, A., Hermann, D. M., Wiendl, H., Meuth, S. G., Faber, C., Diederich, K., et al. (2018) · Annals of Neurology · doi:10.1002/ana.25238 · Cited by 11
Inositol Polyphosphate-5-Phosphatase K ( Inpp5k ) Enhances Sprouting of Corticospinal Tract Axons after CNS Trauma
Kauer, S. D., Croce, K. F., Li, E. H. F., Evans, B. P., Golan, N., & Cafferty, W. B. J. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0897-21.2022 · Cited by 11
Nanoparticle-Mediated Nose-to-Brain Delivery for Ischemic Stroke Therapy: Preclinical Insights
Park, J., & Riew, T. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17111447 · Cited by 10
Neurobiology of Stroke Recovery
Kane, E., & Ward, N. (2021) · Springer eBooks · doi:10.1007/978-3-030-58505-1_1 · Cited by 12
Multiscale imaging informs translational mouse modeling of neurological disease
Wang, Y., LeDue, J. M., & Murphy, T. H. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.006 · Cited by 13
Anti-Nogo-A Antibody Therapy Improves Functional Outcome Following Traumatic Brain Injury
Powers, B. E., Ton, S. T., Farrer, R. G., Chaudhary, S., Nockels, R. P., Kartje, G. L., & Tsai, S. (2023) · Neurorehabilitation and neural repair · doi:10.1177/15459683231203194 · Cited by 11
Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice
Zhong, J., He, Y., Zhao, Q., Luo, H., Zhang, Q., Tian, Y., Liu, Y., Yang, C., Yin, Y., Yu, L., et al. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-03979-y · Cited by 10
Reinforcement Learning is Impaired in the Sub-acute Post-stroke Period
Branscheidt, M., Hadjiosif, A. M., Anaya, M. A., Keller, J. L., Widmer, M., Runnalls, K. D., Luft, A. R., Bastian, A. J., Krakauer, J. W., & Celnik, P. A. (2025) · Neurorehabilitation and neural repair · doi:10.1177/15459683241304352 · Cited by 10
Effect of task-specific training on Eph/ephrin expression after stroke
Choi, D., Ahn, J., Choi, I.-A., Kim, J., Kim, B.-R., & Lee, J. (2016) · BMB Reports · doi:10.5483/bmbrep.2016.49.11.172 · Cited by 10
Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats
Shepherd, D. J., Tsai, S., O’Brien, T. E., Farrer, R. G., & Kartje, G. L. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00467 · Cited by 9
Lesion Area in the Cerebral Cortex Determines the Patterns of Axon Rewiring of Motor and Sensory Corticospinal Tracts After Stroke
Sato, T., Nakamura, Y., Takeda, A., & Ueno, M. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.737034 · Cited by 11
Adaptation in the spinal cord after stroke: Implications for restoring cortical control over the final common pathway
Urbin, M. A. (2024) · The Journal of Physiology · doi:10.1113/jp285563 · Cited by 10
Double viral vector intersectional approaches for pathway-selective manipulation of motor functions and compensatory mechanisms
Isa, T. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113959 · Cited by 9
A wearable robotics assistive device: Design, technical solutions, and implementation
Wedyan, M., Al-Jumaily, A. A., Alnajjar, F., Mohamad, P., & Shimoda, S. (2017) · International Conference on Electrical and Computing Technologies and Applications (ICECTA) · doi:10.1109/icecta.2017.8252059 · Cited by 9
Facilitating Corticomotor Excitability of the Contralesional Hemisphere Using Non-Invasive Brain Stimulation to Improve Upper Limb Motor Recovery from Stroke—A Scoping Review
Tam, P. K., Oey, N. E., Tang, N., Ramamurthy, G., & Chew, E. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13154420 · Cited by 8
Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
Heiser, H., Kiessler, F., Roggenbach, A., Ibañez, V., Wieckhorst, M., Helmchen, F., Gjorgjieva, J., & Wahl, A.-S. (2025) · Nature Communications · doi:10.1038/s41467-025-58688-4 · Cited by 8
Self-citation
Long-range axon branching: contributions to brain network plasticity and repair
Richards, L. J., Huang, C., Bauer, A. Q., & Lee, J. (2026) · Nature reviews. Neuroscience · doi:10.1038/s41583-025-01008-y · Cited by 9
Neural recovery after cortical injury: Effects of MSC derived extracellular vesicles on motor circuit remodeling in rhesus monkeys
Calderazzo, S. M., Covert, M., de Alba, D., Bowley, B. G. E., Pessina, M. A., Rosene, D. L., Buller, B., Medalla, M., & Moore, T. L. (2022) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2022.08.001 · Cited by 8
Disrupting stroke-induced GAT-1-syntaxin1A interaction promotes functional recovery after stroke
Lin, Y., Wu, F., Li, T., Lin, L., Gao, F., Zhu, L., Xu, X.-M., Chen, M.-Y., Hou, Y.-L., Zhang, C.-J., et al. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101789 · Cited by 8
State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research
Wahl, A.-S. (2018) · Neural Plasticity · doi:10.1155/2018/3846593 · Cited by 8
Self-citation
Longitudinal fMRI measures of cortical reactivation and hand use with and without training after sensory loss in primates
Qi, H., Reed, J. L., Wang, F., Gross, C. L., Liu, X., Chen, L. M., & Kaas, J. H. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118026 · Cited by 8
Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid hemorrhage in rats
Wu, X., Wang, Z., Li, H., 谢学顺, Wu, J., Shen, H., Li, X., Wang, Z., & Chen, G. (2021) · Frontiers of Medicine · doi:10.1007/s11684-021-0879-9 · Cited by 8
Molecular Tools for Targeted Control of Nerve Cell Electrical Activity. Part II
Kolesov, D. V., Sokolinskaya, E. L., Lukyanov, K. A., & Bogdanov, A. M. (2021) · Acta Naturae · doi:10.32607/actanaturae.11415 · Cited by 8
Pregabalin improves axon regeneration and motor outcome in a rodent stroke model
Kugler, C., Blank-Stein, N., Matušková, H., Thielscher, C., Reichenbach, N., Lin, T.-C., Bradke, F., & Petzold, G. C. (2022) · Brain Communications · doi:10.1093/braincomms/fcac170 · Cited by 8
Phylogenetic view of the compensatory mechanisms in motor and sensory systems after neuronal injury
Isa, T., Tohyama, T., & Kinoshita, M. (2022) · Current Research in Neurobiology · doi:10.1016/j.crneur.2022.100058 · Cited by 8
Corticospinal-specific Shh overexpression in combination with rehabilitation promotes CST axonal sprouting and skilled motor functional recovery after ischemic stroke
Wu, B., Yang, L., Xi, C., Yao, H., Chen, L., Fan, F., Wu, G., Du, Z., Hu, J., & Hu, S. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03642-y · Cited by 8
Chemogenetic approaches to unravel circuit wiring and related behavior after spinal cord injury
Steenbergen, V. V., & Bareyre, F. M. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113839 · Cited by 8
Combining robotics with enhanced serotonin-driven cortical plasticity improves post-stroke motor recovery
Conti, S., Spalletti, C., Pasquini, M., Giordano, N., Barsotti, N., Mainardi, M., Lai, S., Giorgi, A., Pasqualetti, M., Micera, S., et al. (2021) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2021.102073 · Cited by 7
Neuronal HDAC3 knockdown promotes propriospinal detour pathway formation and locomotor recovery in a mouse model of spinal cord injury
Gao, Z., Xing, H., Shen, Y., Ding, X., Xu, S., Li, R., Zhang, Y., Mao, S., Liu, C., Jin, J., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adp1873 · Cited by 6
Involvement of Denervated Midbrain-Derived Factors in the Formation of Ectopic Cortico-Mesencephalic Projection after Hemispherectomy
Chang, L., Masada, M., Kojima, M., & Yamamoto, N. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1371-21.2021 · Cited by 6
Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke
Jin, S., Chen, X., Zheng, H., Cai, W., Lin, X., Kong, X., Ni, Y., Ye, J., Li, X., Shen, L., et al. (2022) · iScience · doi:10.1016/j.isci.2022.105885 · Cited by 6
Self-citation
Effects of task-based rehabilitative training combined with PTEN/SOCS3 coinhibition promotes axon regeneration and upper extremity skilled motor function recovery after cervical spinal cord injury in adult mice
Pan, L., Yi, L., Liu, Y., Liu, L., Zhu, Y., Zhong, J., Wang, Y., Yin, Y., Yu, L., Tan, B., et al. (2023) · Neuroscience Letters · doi:10.1016/j.neulet.2023.137121 · Cited by 6
Extravasation into brain and subsequent spread beyond the ischemic core of a magnetic resonance contrast agent following a step-down infusion protocol in acute cerebral ischemia
Nagaraja, T. N., Keenan, K. A., Aryal, M. P., Ewing, J. R., Gopinath, S., Nadig, V. S., Shashikumar, S., & Knight, R. A. (2014) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-11-21 · Cited by 6
Breaking Mental Barriers Promotes Recovery After Spinal Cord Injury
Rodocker, H. I., Bordbar, A., Larson, M. J. E., Biltz, R. G., Wangler, L. M., Fadda, P., Godbout, J. P., & Tedeschi, A. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.868563 · Cited by 6
Clinically Applicable Experimental Design and Considerations for Stroke Recovery Preclinical Studies
Karamyan, V. T. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2926-0_25 · Cited by 6
Nogo-A is secreted in extracellular vesicles, occurs in blood and can influence vascular permeability
Rust, R., Holm, M. M., Egger, M., Weinmann, O., van Rossum, D., Walter, F. R., Santa-Maria, A. R., Grönnert, L., Maurer, M. A., Kraler, S. C., et al. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231216270 · Cited by 6
Self-citation
Anti‐ N ogo‐ A antibody: a treatment option for neurogenic lower urinary tract dysfunction?
Schneider, M. P., Schwab, M. E., & Kessler, T. M. (2014) · British Journal of Urology · doi:10.1111/bju.13007 · Cited by 6
Self-citation
Very Early Initiation Reduces Benefits of Poststroke Rehabilitation Despite Increased Corticospinal Projections
Okabe, N., Himi, N., Nakamura‐Maruyama, E., Hayashi, N., Sakamoto, I., Hasegawa, T., & Miyamoto, O. (2019) · Neurorehabilitation and neural repair · doi:10.1177/1545968319850132 · Cited by 6
Compensatory neuromuscular junction adaptations of forelimb muscles in focal cortical ischemia in rats
Bonilla‬, Y. C. E., Castro, P. A. T. D. S., Faturi, F. M., Zambetta, R. M., Lepesteur‐Gianlorenço, A. C., Croti, G., Jones, T. A., & Russo, T. L. (2020) · Brain and Behavior · doi:10.1002/brb3.1472 · Cited by 6
Feasibility of commonly used fluorescent dyes and viral tracers in aqueous and solvent-based tissue clearing
Wang, P., Zhang, D., Bai, S., Tao, B., Li, S., Wang, T., & Shang, A. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135301 · Cited by 6
Bumetanide: A review of its neuroplasticity and behavioral effects after stroke
Tao, D., Liu, F., Sun, X., Qu, H., Zhao, S., Zhou, Z., Xiao, T., Zhao, C., & Zhao, M. (2019) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-190926 · Cited by 6
Asynchronous therapy targeting Nogo-A enhances neurobehavioral recovery by reducing neuronal loss and promoting neurite outgrowth after cerebral ischemia in mice
Li, L., Deng, B., Wang, S., Zhong, H., Liu, Z., Jin, W., Jiang, T., Xiao, Z., & Wang, Q. (2015) · Journal of drug targeting · doi:10.3109/1061186x.2015.1052070 · Cited by 6
Ghrelin promotes neurologic recovery and neurogenesis in the chronic phase after experimental stroke
Beuker, C., Schreiner, U., Strecker, J.-K., Altach, E., Rätzel, V., Schmidt-Pogoda, A., Wiendl, H., Minnerup, J., & Diederich, K. (2025) · Neurological Research and Practice · doi:10.1186/s42466-025-00371-6 · Cited by 5
Pre-stroke weight loss by glucagon-like peptide 1 receptor and neuropeptide Y receptor Y2 activation improves post-stroke functional recovery in male diabetic mouse models
Vercalsteren, E., Karampatsi, D., Neicu, M., Romanitan, M. O., Haebel, P., Bleymehl, K., Nyström, T., Klein, T., Darsalia, V., & Patrone, C. (2025) · Diabetologia · doi:10.1007/s00125-025-06567-4 · Cited by 5
SpinalTRAQ: A Novel Pipeline for Volumetric Cervical Spinal Cord Analysis Identifies the Corticospinal Tract Synaptic Projectome in Healthy and Post-stroke Mice
Poinsatte, K., Kenwood, M. R., Betz, D., Nawaby, A., Ajay, A. D., Xu, W., Plautz, E. J., Kong, X., Meeks, J. P., Ramirez, D. M. O., et al. (2025) · eNeuro · doi:10.1523/eneuro.0276-25.2025 · Cited by 5
“Time Is Brain” – for Cell Therapies
Yin, H. R., Brian, D., Weber, R., Lyden, P. D., & Rust, R. (2025) · Advanced Science · doi:10.1002/advs.202519579 · Cited by 5
Synergistic effect of chemogenetic activation of corticospinal motoneurons and physical exercise in promoting functional recovery after spinal cord injury
Lin, X., Wang, X., Zhang, Y., Chu, G., Liang, J., Zhang, B., Lu, Y., Steward, O., & Luo, J. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114549 · Cited by 5
Proliferation of Bilateral Nerve Fibers Following Thalamic Infarction Contributes to Neurological Function Recovery: A Diffusion Tensor Imaging (DTI) Study
Liu, Y., Chen, L., Zeng, J., Li, W., Zeng, S., Ye, B., & Liang, Z. (2018) · Medical Science Monitor · doi:10.12659/msm.909071 · Cited by 5
Activation of GABA A receptors enhances the behavioral recovery but not axonal sprouting in ischemic rats
Wang, H., Cheng, X., Yu, H., Zhang, X., Guan, M., Zhao, L., Liu, Y., Linag, Y., Luo, Y., & Zhao, C. (2019) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-180827 · Cited by 5
Therapeutic exercise accompanied by neuronal modulation to enhance neurotrophic factors in the brain with central nervous system disorders
Maejima, H., Inoue, T., & Takamatsu, Y. (2019) · Physical Therapy Research · doi:10.1298/ptr.r0004 · Cited by 7
The Recognition of the Distribution Features of Corticospinal Neurons by a Retrograde Trans-synaptic Tracing to Elucidate the Clinical Application of Contralateral Middle Trunk Transfer
Wang, F., Shen, J., Jiang, S., Qiu, Y., Ye, X., Wang, C., Liang, C., & Xu, W. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.09.030 · Cited by 5
Spontaneous Neuronal Plasticity in the Contralateral Motor Cortex and Corticospinal Tract after Focal Cortical Infarction in Hypertensive Rats
Huang, X., Wang, X., Yang, M., Pan, X., Duan, M., Wen, X., Cai, H., Jiang, G., & Chen, L. (2020) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2020.105235 · Cited by 5
Temporal and Spatial Gene Expression Profile of Stroke Recovery Genes in Mice
Götz, J., Wieters, F., Fritz, V. J., Käsgen, O., Kalantari, A., Fink, G. R., & Aswendt, M. (2023) · Genes · doi:10.3390/genes14020454 · Cited by 5
The pericontused cortex can support function early after TBI but it remains functionally isolated from normal afferent input
Paydar, A., & Harris, N. G. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114260 · Cited by 5
Subcutaneous Neurotrophin-3 infusion induces corticospinal neuroplasticity and improvements in dexterity and walking in elderly rats after large cortical strokePreprint
Duricki, D. A., Kakanos, S. G., Haenzi, B., Wayman, C., Bödecker, N., Vogelgesang, A., Cash, D., & Moon, L. D. F. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/427864 · Cited by 5
Mutanobactin-D, a Streptococcus mutans Non-Ribosomal Cyclic Lipopeptide, Induces Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells and Human Bone Marrow Stem Cells
Nikolić, S., Alastra, G., Pultar, F., Lüthy, L., Stadlinger, B., Carreira, E. M., Bugueno, I. M., & Mitsiadis, T. A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031144 · Cited by 4
A versatile odor detection system based on automatically trained rats for chemical sensing
Oh, Y., Kim, M., Kwon, O. S., Min, S. S., Shin, Y., Kim, K. K., Oh, M., & Kim, M. (2023) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2023.10.042 · Cited by 4
Blocking the Nogo-A Signaling Pathway to Promote Regeneration and Plasticity After Spinal Cord Injury and Stroke
Guzik-Kornacka, A., Vajda, F., & Schwab, M. E. (2016) · Springer eBooks · doi:10.1007/978-1-4899-7654-3_20 · Cited by 4
Self-citation
Role and limitations of rehabilitation-induced neural network remodeling after stroke
Okabe, N., & Miyamoto, O. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.241450 · Cited by 4
Exercise-induced Nogo-A influences rodent motor learning in a time-dependent manner
Stehle, J. H., Sheng, Z., Hausmann, L., Bechstein, P., Weinmann, O., Hernesniemi, J. A., Neimat, J. S., Schwab, M. E., & Zemmar, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250743 · Cited by 4
Self-citation
Neuromuscular Stimulation as an Intervention Tool for Recovery from Upper Limb Paresis after Stroke and the Neural Basis
Obayashi, S., & Saito, H. (2022) · Applied Sciences · doi:10.3390/app12020810 · Cited by 4
Nicotinic acetylcholine signaling is required for motor learning but not for rehabilitation from spinal cord injury
Li, Y., & Li, Y. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.346544 · Cited by 4
Spontaneously regenerative corticospinal neurons in micePreprint
Fait, B. W., Cotto, B., Murakami, T. C., Hagemann-Jensen, M., Zhan, H., Freivald, C., Turbek, I., Gao, Y., Yao, Z., Way, S. W., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.09.612115 · Cited by 4
Crossing nerve transfer restores limb movement by reorganizing the cortico-rubro-spinal pathway in peripheral nerve injury
Pang, Z., Chen, Y., Tong, C., Chen, Y., Lei, G., Cai, Z., Zhu, S., Shen, Y., Liang, Z., Zhang, J., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116192 · Cited by 2
Suppression of Microglial ERO1a Alleviates Inflammation and Enhances the Efficacy of Rehabilitative Training After Ischemic Stroke
Ren, J., Lv, Y., Tian, Q., Sun, L., Miao, P., Yang, X., Xu, L., Feng, C., Li, M., Gu, Q., et al. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03333-8 · Cited by 2
Factors influencing brain recovery from stroke via possible epigenetic changes
Rroji, O., & Mucignat‐Caretta, C. (2024) · Future Science OA · doi:10.1080/20565623.2024.2409609 · Cited by 2
Timing Is Everything in Corticospinal Tract Recovery After Stroke
Moses, Z. B., Abd‐El‐Barr, M. M., & Chi, J. H. (2015) · Neurosurgery · doi:10.1227/01.neu.0000462697.23265.f4 · Cited by 2
Spatiotemporal Parsing of Motor Kinematics for Assessing Stroke Recovery
Antić, B., Büchler, U., Wahl, A.-S., Schwab, M. E., & Ommer, B. (2015) · Lecture notes in computer science · doi:10.1007/978-3-319-24574-4_56 · Cited by 2
Self-citation
An unexpected role of Nogo-A as regulator of tooth enamel formation
Pagella, P., Lai, C. F., Pirenne, L., Cantù, C., Schwab, M. E., & Mitsiadis, T. A. (2024) · International Journal of Oral Science · doi:10.1038/s41368-024-00323-x · Cited by 2
Self-citation
Enhancing plasticity in spinal sensorimotor circuits following injuries to facilitate recovery of motor control
Dickson, R. G., Lall, V. K., & Ichiyama, R. M. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.02.005 · Cited by 2
Quantitative Spatial Mapping of Axons Across Cortical Regions to Assess Axonal Sprouting After Stroke
Joy, M. T., Bridges, S. P., & Carmichael, S. T. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2926-0_13 · Cited by 1
Preclinical Evidence of Nogo-A Inhibition in Stroke Recovery: A Scoping Review
Lima, J. E. E., Rengarajan, S., Wahl, A.-S., Srivatsan, A., Strittmatter, S. M., Carmichael, S. T., George, P. M., Sheth, K. N., Schwab, M. E., & Lansberg, M. G. (2025) · Stroke · doi:10.1161/strokeaha.124.049361 · Cited by 1
Self-citation
ReachingBot: An automated and scalable benchtop device for highly parallel Single Pellet Reach-and-Grasp training and assessment in mice
Kakanos, S. G., Gadiagellan, D., Kim, E., Cash, D., & Moon, L. D. F. (2023) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2023.109908 · Cited by 1
MEP-Guided Scalp Acupuncture Combined with Repetitive Transcranial Magnetic Stimulation for Post-Stroke Upper Extremity Motor Impairment: A Randomized Controlled Study Protocol
Kong, D., Huang, X., Zhang, S., Chen, K., Gao, H., & Xie, H. (2026) · International Journal of General Medicine · doi:10.2147/ijgm.s582719 · Cited by 1
Integrating Molecular, Cellular, and Systems Approaches to Repairing the Brain After Stroke
Krucoff, M. O., Harward, S. C., Rahimpour, S., Dombrowski, K. E., Hauck, E. F., Lad, S. P., & Turner, D. A. (2017) · Springer series in translational stroke research · doi:10.1007/978-3-319-66679-2_18 · Cited by 1
Plastizität nach Schlaganfall: ein Schlüssel zu Verbesserungen in der Neurorehabilitation
Branscheidt, M., Luft, A. R., Menig, A., & Jurkic, Z. (2023) · neuroreha · doi:10.1055/a-2180-8968 · Cited by 1
Tissue optical clearing imaging for structural changes of neuromuscular junctions after mice ischemic stroke [Invited]
Xu, J., Dai, Y., Xuan, A., Yao, Y., Liu, S., Yu, T., & Zhu, D. Y. (2023) · Chinese Optics Letters · doi:10.3788/col202321.120061 · Cited by 1
Scg2 drives corticospinal circuit reorganization with spinal premotor interneurons and astrocytes for motor recovery after stroke in mice
Sato, T., Nakamura, Y., Hoshina, K., Inoue, K., Takada, M., Yano, M., Matsuzawa, H., & Ueno, M. (2026) · Nature Communications · doi:10.1038/s41467-026-73518-x · Cited by 1
Methods for the analysis of neuronal plasticity and brain connectivity during neurological recovery
Sánchez-Mendoza, E. H., de Carvalho, T. S., & Hermann, D. M. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.194704 · Cited by 1
In vivo Use of Dextran-based Anterograde Cortical Tracers to Assess the Integrity of the Cortical Spinal Tract
Wiersma, A. M., & Winship, I. R. (2018) · BIO-PROTOCOL · doi:10.21769/bioprotoc.2463 · Cited by 1
Augmenting Plasticity and Recovery from Stroke by Modulating the Extracellular Matrix of the Central Nervous System
Wiersma, A. M. (2017) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3v698s16 · Cited by 1
Hot Topics in Cellular Neuropathology II: Promoting Neuronal Plasticity in the Injured Central Nervous System
Hermann, D. M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.927980 · Cited by 1
Editorial: Hot topics in cellular neuropathology, volume II: promoting neuronal plasticity in the injured central nervous system
Hermann, D. M., Bacigaluppi, M., & Peruzzotti‐Jametti, L. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1269763 · Cited by 1
Editorial: Rehabilitation to guide functional plasticity and regeneration with novel cellular, pharmacological and neuromodulation therapies
Mestriner, R. G., Kalsi‐Ryan, S., Gholamrezaei, G., & Balbinot, G. C. (2025) · Frontiers in Rehabilitation Sciences · doi:10.3389/fresc.2025.1563975 · Cited by 1
Rehabilitation drives functional reorganization of intact corticospinal-supraspinal projections following partial spinal cord injuryPreprint
Bonanno, J., Trivedi, S., O’Brien, C. F., Saha, S., & Cafferty, W. B. J. (2025) · eLife · doi:10.64898/2025.12.12.694014 · Cited by 1
Timing is everything for Nogo-specific antibodies
Cully, M. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4397
Cerebrovascular Infarct
Sontheimer, H. W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800244-5.00001-x
Task Practice with or without Cellular Transplantation Promotes Recovery of Reach-to Grasp Function after Cervical Spinal Cord Injury
Stackhouse, S. K. (2014) · International Journal of Physical Medicine & Rehabilitation · doi:10.4172/2329-9096.1000239
Rehabilitation promotes the recovery of functional and structural features of healthy neuronal networks after strokePreprint
Mascaro, A. L. A., Conti, E., Lai, S., Giovanna, A. P. D., Spalletti, C., Alia, C., Quarta, E., Panarese, A., Sacconi, L., Micera, S., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/141697
Investigating Effects of Metformin and Enriched Rehabilitation on Perinatal Hypoxia-Ischemia
Antonescu, S. (2017) · uO Research (University of Ottawa) · doi:10.20381/ruor-20998
Structural Neural Plasticity During Stroke Recovery * *This work was supported by operating, salary, and equipment grants to C.E.B. from CIHR, Heart and Stroke Foundation of BC and Yukon, MSFHR, NSERC, and CFI.
Gerrow, K., & Brown, C. E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803784-3.00003-2 · Cited by 1
In vivo Use of Dextran-based Anterograde Cortical Tracers to Assess the Integrity of the Cortical Spinal Tract
Wiersma, A. M., & Winship, I. R. (2018) · BIO-PROTOCOL · doi:10.21769/bioprotoc.2862
Rehabilitation Promotes the Recovery of Functional and Structural Features of Healthy Neuronal Networks after StrokePreprint
Mascaro, A. L. A., Conti, E., Lai, S., Giovanna, A. P. D., Spalletti, C., Alia, C., Panarese, A., Sacconi, L., Micera, S., Caleo, M., et al. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3233815

Authors: Wahl, A. S., Omlor, W., Rubio, J. C., Chen, J. L., Zheng, H., Schröter, A., Gullo, M., Weinmann, O., Kobayashi, K., Helmchen, F., Ommer, B., & Schwab, M. E.
Affiliations: University of Zurich (CH)
Heidelberg University (DE)
Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland.
National Institute for Physiological Sciences (JP)
Corresponding author: Wahl, A. S.
Schwab, M. E.
ORCID: Wahl, A. S.
Omlor, W.
Rubio, J. C.
Chen, J. L.
Zheng, H.
Gullo, M.
Weinmann, O.
Kobayashi, K.
Helmchen, F.
Ommer, B.
Schwab, M. E.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2014-06-13
Volume: 344
Issue: 6189
Pages: 1250-1255
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.1253050
OpenAlex: W2001165604
Cited by: 322
References: 34
Citations by year: 2026: 7 · 2025: 25 · 2024: 11 · 2023: 23 · 2022: 30 · 2021: 28 · 2020: 23 · 2019: 35 · 2018: 29 · 2017: 42 · 2016: 33 · 2015: 26 · 2014: 10
FWCI: 35.92
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
Funders: Japan Society for the Promotion of Science (25560436)
Topics: Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
Health Sciences › Medicine › Clinical Neurology › Spinal Cord Injury Research
Keywords: stroke, corticospinal tract, motor recovery, immunotherapy, neurite outgrowth inhibition, axonal sprouting, forelimb function, motor rehabilitation, intensive training, spinal cord, pharmacogenetics, functional recovery
MeSH terms: Nogo Proteins, Stroke Rehabilitation, Animals, Female, Immunotherapy, Motor Cortex, Myelin Proteins, Physical Conditioning, Animal, Pyramidal Tracts, Prosencephalon, Recovery of Function, Rats, Long-Evans, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks