Cited by 142Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesDeep Brain Stimulation and Movement Disorders

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Intracranial Self-Stimulation in Man

Bishop, M. P., Elder, S. Thomas, Heath, Robert G.·1963·Science

DOI 10.1126/science.140.3565.394

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Abstract

Intracranial self-stimulation techniques, modified for use with neuropsychiatric patients, provide data suggestive of positive and negative reinforcing properties of brief electrical stimulation to various subcortical structures of the human brain.

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Crossref · 10.1126/science.140.3565.394

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BECKER, H.C., A ROENTGENOGRAPHIC STEREOTAXIC TECHNIQUE FOR IMPLANTING AND MAINTAINING ELECTRODES IN THE BRAIN OF MAN, ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY 9: 533 (1957). · DOI
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HEATH, R.G., COMMON CHARACTERISTICS OF EPILEPSY AND SCHIZOPHRENIA - CLINICAL OBSERVATION AND DEPTH ELECTRODE STUDIES, AMERICAN JOURNAL OF PSYCHIATRY 118: 1013 (1962). · DOI
Heath, R. G., Electrical Studies on the Unanesthetized Brain: 214 (1960).
Heath, R. G., Psychosomatic Medicine: 228 (1962).
Heath, R. G., Studies In Schizophrenia: 46 (1954).
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HIGGINS, J.W., BEHAVIORAL CHANGES DURING INTRACEREBRAL ELECTRICAL STIMULATION, ARCHIVES OF NEUROLOGY AND PSYCHIATRY 76: 399 (1956). · DOI
Olds, J., Electrical Stimulation of the Brain: 425 (1961).
OLDS, J, POSITIVE REINFORCEMENT PRODUCED BY ELECTRICAL STIMULATION OF SEPTAL AREA AND OTHER REGIONS OF RAT BRAIN, JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 47: 419 (1954). · DOI · Paper page
OLDS, J, EFFECTS OF HUNGER AND MALE SEX HORMONE ON SELF-STIMULATION OF THE BRAIN, JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 51: 320 (1958). · DOI
OLDS, J, HYPOTHALAMIC SUBSTRATES OF REWARD, PHYSIOLOGICAL REVIEWS 42: 554 (1962). · DOI
Sem-Jacobsen, C. W., Electrical Studies on the Unanesthetized Brain: 280 (1960).
Sem-Jacobsen, C. W., Electroencephalography and Clinical Neurophysiology 11: 379 (1959).

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Authors: Bishop, M. P., Elder, S. T., & Heath, R. G.
Affiliations: Tulane University (US)
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 1963-04-26
Volume: 140
Issue: 3565
Pages: 394-396
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.140.3565.394
OpenAlex: W2012590570
Cited by: 142
References: 0
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 7 · 2022: 6 · 2021: 6 · 2020: 7 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 4 · 2015: 8 · 2014: 8 · 2013: 6 · 2012: 5
FWCI: 1.95
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Keywords: intracranial self-stimulation, electrical brain stimulation, reinforcement, positive reinforcement, negative reinforcement, subcortical structures, neuropsychiatric patients, human brain
MeSH terms: Brain, Electric Stimulation, Electrophysiology, Reinforcement, Psychology, Self Stimulation

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Intracranial Self-Stimulation in Man

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