Artificial Vision for the Blind: Electrical Stimulation of Visual Cortex Offers Hope for a Functional Prosthesis

Dobelle, W. H., Mladejovsky, M. G., Girvin, J. P.·1974·Science

DOI 10.1126/science.183.4123.440

Cited by (441)

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Tucker Tomlinson, Lee E. Miller · 2016 · Advances in experimental medicine and biology
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P. F. Johnson, Jonathan J. Bernstein, Gale D. Hunter, W.W. Dawson, Larry L. Hench · 1977 · Journal of Biomedical Materials Research
Retinal prostheses: Clinical results and future challenges
Serge A. Picaud, José‐Alain Sahel · 2014 · Comptes Rendus Biologies
Perceived intensity of somatosensory cortical electrical stimulation
Fridman, Gene Y., Blair, Hugh T., Blaisdell, Aaron P., Judy, Jack W. · 2010 · Experimental Brain Research
Advances in visual prostheses: engineering and biological challenges
Borda, Eleonora, Ghezzi, Diego · 2022 · Progress in Biomedical Engineering
Positive visual phenomena in space: A scientific case and a safety issue in space travel
Walter G. Sannita, Livio Narici, Piergiorgio Picozza · 2006 · Vision Research
Enhanced Performance with Brain Stimulation: Attentional Shift or Visual Cue?
James R. Cavanaugh, Bryan D. Alvarez, Robert H. Wurtz · 2006 · Journal of Neuroscience
Mapping the Representation of the Visual Field by Electrical Stimulation of Human Visual Cortex
Wm. H. Dobelle, Joseph Turkel, David C. Henderson, Jerald R. Evans · 1979 · American Journal of Ophthalmology
Retinal replacement—the development of microelectronic retinal prostheses—experience with subretinal implants and new aspects
Helmut G. Sachs, Veit‐Peter Gabel · 2004 · Graefe s Archive for Clinical and Experimental Ophthalmology
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Troyk, Philip R. · 2017 · Artificial Vision
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Nicholas V. Apollo, Brendan B. Murphy, Kayla Prezelski, Nicolette Driscoll, Andrew G. Richardson, Timothy H. Lucas, Flavia Vitale · 2020 · Journal of Neural Engineering
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Gregg Jorgen Suaning, Nigel Hamilton Lovell, Klaus Schindhelm, Minas T. Coroneo · 1998 · Australian and New Zealand Journal of Ophthalmology
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Helmut G. Sachs, Thomas Schanze, Marcus Wilms, Andreas Rentzos, Ursula Brunner, Florian Gekeler, Lutz Hesse · 2004 · Graefe s Archive for Clinical and Experimental Ophthalmology
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Implantation of electronic visual prosthesis for blindness restoration
Jiuk Jang, Hyobeom Kim, Young Min Song, Jang‐Ung Park · 2019 · Optical Materials Express
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Takashi D.Y. Kozai, Nicolas Alexander Alba, Huanan Zhang, Nicholas A. Kotov, Robert A. Gaunt, Xinyan Tracy Cui · 2014 · Springer eBooks
Visual prosthetics 2006: assessment and expectations
Gislin Dagnelie · 2006 · Expert Review of Medical Devices
Retinotopic map on the visual cortex for eccentrically placed patterns: First noninvasive measurement
Edward L. Maclin, Yoshio C Okada, Lloyd Kaufman, Samuel J. Williamson · 1983 · Il Nuovo Cimento D
Multi-electrode stimulation evokes consistent spatial patterns of phosphenes and improves phosphene mapping in blind subjects
Denise N. Oswalt, William H. Bosking, Ping Sun, Sameer Anil Sheth, Soroush Niketeghad, Michelle Armenta Salas, Uday K. Patel, Robert J. Greenberg, Jessy D. Dorn, Nader Pouratian et al. · 2021 · Brain stimulation
Visual resolution with epi-retinal electrical stimulation estimated from activation profiles in cat visual cortex
Marcus Wilms, Marcus Eger, Thomas Schanze, REINHARD ECKHORNdagger · 2003 · Visual Neuroscience
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M. Bunge · 1987 · Behavioral and Brain Sciences
Electrical induction of vision
Tehovnik, Edward J., Slocum, Warren M. · 2013 · Neuroscience & Biobehavioral Reviews
Estimating Phosphene Maps for Psychophysical Experiments used in Testing a Cortical Visual Prosthesis Device
Nishant Srivastava, Philip R. Troyk, Vernon L. Towle, Daniel J. Curry, E M Schmidt, Conrad V. Kufta, Gislin Dagnelie · 2007 · International IEEE/EMBS Conference on Neural Engineering
The Authenticity of Machine-Augmented Human Intelligence: Therapy, Enhancement, and the Extended Mind
Allen Coin, Veljko Dubljević · 2020 · Neuroethics
Building the bionic eye: an emerging reality and opportunity
Lotfi B. Merabet · 2011 · Progress in brain research
Image Processing Strategies Dedicated to Visual Cortical Stimulators: A Survey
Louis‐Xavier Buffoni, Jonathan Coulombe, Mohamad Sawan · 2005 · Artificial Organs
Transscleral implantation and neurophysiological testing of subretinal polyimide film electrodes in the domestic pig in visual prosthesis development
Helmut G. Sachs, Thomas Schanze, Ursula Brunner, Heiko Sailer, Christoph Wiesenack · 2005 · Journal of Neural Engineering
Nanosensor networks for smart health care
Tooba Khan, Meltem Civas, Oktay Cetinkaya, Naveed Ahmed Abbasi, Özgür B. Akan · 2020 · Elsevier eBooks
Cortical slow potentials and the occipital EEG in congenital blindness
Jeffrey L. Noebels, Walton T. Roth, Bert S. Kopell · 1978 · Journal of the Neurological Sciences
Face identity recognition in simulated prosthetic vision is poorer than previously reported and can be improved by caricaturing
Jessica L. Irons, Tamara Gradden, Angel Zhang, Xuming He, Nick M. Barnes, Adele F. Scott, Elinor McKone · 2017 · Vision Research
Positron Emission Tomographic Studies of Local Cerebral Glucose Metabolism in Humans in Physiological and Pathophysiological Conditions
Martin Reivich, Abass A. Alavi · 1983 · Advances in metabolic disorders
Chronic stability of a neuroprosthesis comprising multiple adjacent Utah arrays in monkeys
Xing Chen, Feng Wang, Roxana N. Kooijmans, Peter Christiaan Klink, Christian Boehler, Maria Asplund, Pieter R. Roelfsema · 2023 · Journal of Neural Engineering
Advances in Retinal Neuroprosthetics
Nigel Hamilton Lovell, Luke E. Hallum, Spencer C. Chen, Socrates Dokos, Philip Byrnes‐Preston, Rylie A. Green, Laura Anne Poole-Warren, Torsten Lehmann, Gregg Jorgen Suaning · 2006 · Wiley eBooks
Phosphene perceptions and safety of chronic visual cortex stimulation in a blind subject
Niketeghad, Soroush, Muralidharan, Abirami, Patel, Uday, Dorn, Jessy D., Bonelli, Laura, Greenberg, Robert J., Pouratian, Nader · 2020 · Journal of Neurosurgery
Retinal Prosthetic Approaches to Enhance Visual Perception for Blind Patients
Shinyong Shim, Kyungsik Eom, Joonsoo Jeong, Sung June Kim · 2020 · Micromachines
Electrical stimulation with a penetrating optic nerve electrode array elicits visuotopic cortical responses in cats
Yiliang Lu, Yan Yan, Xinyu Chai, Qiushi Ren, Yao Chen, Liming Li · 2013 · Journal of Neural Engineering
The Layer 7 Cortical Interface: A Scalable and Minimally Invasive Brain–Computer Interface Platform
Hettick, Mark, Ho, Elton, Poole, Adam J., Monge, Manuel, Papageorgiou, Demetrios, Takahashi, Kazutaka, LaMarca, Morgan, Trietsch, Daniel, Reed, Kyle, Murphy, Mark et al. · 2022
Implantation, removal and replacement of subretinal electronic implants for restoration of vision in patients with retinitis pigmentosa
Katrin Gekeler, Karl Ulrich Bartz‐Schmidt, Helmut G. Sachs, Robert Edward MacLaren, Katarína Štingl, Eberhart Zrenner, Florian Gekeler · 2018 · Current Opinion in Ophthalmology
Intracortical Microelectrode Array Unit Yield under Chronic Conditions: A Comparative Evaluation
Joshua O. Usoro, Brandon S. Sturgill, Kate C. Musselman, Jeffrey R. Capadona, Joseph Jewell Pancrazio · 2021 · Micromachines
Investigation of thermal effects of infrared lasers on the rabbit retina: a study in the course of development of an active subretinal prosthesis
Heiko Sailer, Kei Shinoda, Georgios Blatsios, Konrad Köhler, L. Bondzio, Eberhart Zrenner, Florian Gekeler · 2007 · Graefe s Archive for Clinical and Experimental Ophthalmology
Audio–Vision Substitution for Blind Individuals: Addressing Human Information Processing Capacity Limitations
David J. Brown, Michael J. Proulx · 2016 · IEEE Journal of Selected Topics in Signal Processing
Microelectronic Visual Prostheses
David Daomin Zhou, Robert J. Greenberg · 2009 · Biological and medical physics series
Simplification of Visual Rendering in Simulated Prosthetic Vision Facilitates Navigation
Victor Vergnieux, Marc J.‐M. Macé, Christophe Jouffrais · 2017 · Artificial Organs
Percepts evoked by multi-electrode stimulation of human visual cortex
William H. Bosking, Denise N. Oswalt, Brett L. Foster, Ping Sun, Michael S. Beauchamp, Daniel Yoshor · 2022 · Brain stimulation
Auditory and visual sensations stimulated by low‐frequency electric currents
Donald J. Adrian · 1977 · Radio Science
Implantation and testing of subretinal film electrodes in domestic pigs
Thomas Schanze, Helmut G. Sachs, Christoph Wiesenack, Ursula Brunner, Heiko Sailer · 2005 · Experimental Eye Research
A fast intracortical brain–machine interface with patterned optogenetic feedback
Aamir Abbasi, Dorian Goueytes, Daniel E. Shulz, Valérie Ego‐Stengel, Luc Estebanez · 2018 · Journal of Neural Engineering
A Computer-Based Brain Stimulation System to Investigate Sensory Prostheses for the Blind and Deaf
M. G. Mladejovsky, Donald K. Eddington, Jerald R. Evans, William H. Dobelle · 1976 · IEEE Transactions on Biomedical Engineering
A narrative review of cortical visual prosthesis systems: the latest progress and significance of nanotechnology for the future
Xi Liu, Peipei Chen, Xuemeng Ding, Anning Liu, Peng Li, Cheng Sun, Huaijin Guan · 2022 · Annals of Translational Medicine
Looking ahead: planning for the first human intracortical visual prosthesis by using pilot data from focus groups of potential users
Frank John Lane, MARGARET HELLIE HUYCK, Philip R. Troyk · 2010 · Disability and Rehabilitation Assistive Technology
CMOS stimulating chips capable of wirelessly driving 473 electrodes for a cortical vision prosthesis
Wong, Yan T, Feleppa, Timothy, Mohan, Anand, Browne, Damien, Szlawski, Julian, Rosenfeld, Jeffrey V, Lowery, Arthur · 2019 · Journal of Neural Engineering
Entwicklung einer epiretinalen Prothese zur Stimulation der humanen Netzhaut
M. Feucht, Thomas Laube, Norbert Bornfeld, Peter Walter, Michaela Velikay‐Parel, Ralf Hornig, G. Richard · 2005 · Der Ophthalmologe
Microsensors and microbiosensors for retinal implants
Dency David · 2005 · Frontiers in bioscience
Hypnosis, psi, and the psychology of anomalous experience
R. Nadon, J. Kihlstrom · 1987 · Behavioral and Brain Sciences
Visual Sensation by Electrical Stimulation Using a New Direct Optic Nerve Electrode Device
Kentaro Nishida, Hirokazu Sakaguchi, Motohiro Kamei, Carmen Cecilia-Gonzalez, Yasuo Terasawa, Raúl Vélez-Montoya, Takashi Fujikado, Rafael Sánchez-Fontán, Motoki Ozawa, Hugo Quiroz-Mercado et al. · 2015 · Brain stimulation
The History and Horizons of Microscale Neural Interfaces
Takashi D.Y. Kozai · 2018 · Micromachines
Stochastic resonance in the sensory systems and its applications in neural prosthetics
Patrick Matthews, Pratik Raul, Lawrence M. Ward, Jeroen J. A. van Boxtel · 2024 · Clinical Neurophysiology
Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation
Mark Hettick, Elton Ho, Adam J. Poole, Manuel Monge, Demetrios Papageorgiou, Kazutaka Takahashi, Morgan LaMarca, Daniel Trietsch, Kyle Reed, Mark E. Murphy et al. · 2025 · Nature Biomedical Engineering
ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS
Stanislao Rizzo, P.O. Barale, S. Scheer, Robert G. Devenyi, Marie‐Noëlle Delyfer, Jean‐François Korobelnik, Aleksandra V Rachitskaya, Alex Yuan, Thiran Jayasundera, David N. Zacks et al. · 2018 · Retina
Responses of potential users to the intracortical visual prosthesis: final themes from the analysis of focus group data
Frank John Lane, MARGARET HELLIE HUYCK, Philip R. Troyk, Kenneth Schug · 2012 · Disability and Rehabilitation Assistive Technology
Electrotactile Stimulator for Artificial Proprioception
Percy Nohama, Andréa Vizzotto Lopes, Alberto Cliquet · 1995 · Artificial Organs
Reconfigurable graded adaptive asymmetry-Schottky-barrier phototransistor for artificial visual system with zJ-energy record
Honglin Song, Yanran Li, Shuo Liu, Xilong Zhou, Yu Zhou, Jie Jiang · 2025 · Applied Physics Reviews
Visual objects in the auditory system in sensory substitution: How much information do we need?
Brown, David J., Simpson, Andrew J. R., Proulx, Michael J. · 2014 · Multisensory Research
Safety, efficacy, and quality control of a photoelectric dye-based retinal prosthesis (Okayama University-type retinal prosthesis) as a medical device
Toshihiko Matsuo, Tetsuya Uchida, Kenichi Takarabe · 2009 · Journal of Artificial Organs
Using independent component analysis to remove artifacts in visual cortex responses elicited by electrical stimulation of the optic nerve
Yiliang Lu, Pengjia Cao, Jingjing Sun, Jing Wang, Liming Li, Qiushi Ren, Yao Chen, Xinyu Chai · 2012 · Journal of Neural Engineering
Some suggestions from sociology of science to advance the psi debate
T. Pinch · 1987 · Behavioral and Brain Sciences
Disentangling Function from Benefit: Participant Perspectives from an Early Feasibility Trial for a Novel Visual Cortical Prosthesis
Lilyana Levy, Hamasa Ebadi, Ally Peabody Smith, Lauren Taiclet, Nader Pouratian, Ashley Feinsinger · 2023 · AJOB Neuroscience
Prosthetic Visual Acuity in Irregular Phosphene Arrays Under Two Down-Sampling Schemes: A Simulation Study
Shanquing Cai, Lin Fu, Hui Zhang, Guangshu Hu, Zuoqing Liang · 2005 · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Electrocutaneous stimulation L The effects of stimulus parameters on absolute threshold
John P. Girvin, Lawrence E. Marks, John L. Antunes, Donald O. Quest, Michael D. O’Keefe, Peter Ning, Wm. H. Dobelle · 1982 · Perception & Psychophysics
Towards the cortical representation of form and motion stimuli generated by a retina implant
Thomas Schanze, Nina Greve, Lutz Hesse · 2003 · Graefe s Archive for Clinical and Experimental Ophthalmology
Focal Electrical Stimulation of Cortical Functional Networks
Jia Ming Hu, Mei Zhen Qian, Hisashi Tanigawa, Xue Mei Song, Anna Wang Roe · 2020 · Cerebral Cortex
Automatic object extraction and reconstruction in active video
Ye Lü, Ze-Nian Li · 2007 · Pattern Recognition
Biomedical Implantable Microelectronics
JAMES D. MEINDL · 1980 · Science
Image Recognition With a Limited Number of Pixels for Visual Prostheses Design
Sheng Li, Jie Hu, Xinyu Chai, Yinghong Peng · 2011 · Artificial Organs
A Survey of Vision Aids for the Blind
Jihong Liu, Xiaoye Sun · 2006 · World Congress on Intelligent Control and Automation
Stand des subretinalen Implantatprojekts
Florian Gekeler, Eberhart Zrenner · 2005 · Der Ophthalmologe
Excitation of visual cortex neurons by local intracortical microstimulation
Steven F. Ronner, Bothwell G. Lee · 1983 · Experimental Neurology
Journey of Visual Prosthesis with Progressive Development of Electrode Design Techniques and Experience with CMOS Image Sensors: A Review
Ashish Tiwari, R. H. Talwekar · 2018 · IETE Journal of Research
Sensory Neural Prostheses
Philip R. Troyk, Stuart F. Cogan · 2007 · Springer eBooks
Neural stimulation: Clinical and laboratory experiences
Robert H. Pudenz · 1993 · Surgical Neurology
AN INTRAOCULAR CAMERA FOR RETINAL PROSTHESES: RESTORING SIGHT TO THE BLIND
Noelle R. B. Stiles, Benjamin Patrick McIntosh, Patrick J. Nasiatka, MICHELLE C. HAUER, James David Weiland, Mark S. Humayun, Armand R. Tanguay · 2010 · Advanced series in applied physics
5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood
Nathalie Lombaert, Maroussia Hennes, Sara R. J. Gilissen, Giel Schevenels, Laetitia Aerts, Ria Vanlaer, Lieve Geenen, Ann Van Eeckhaut, Ilse Julia Smolders, Julie Nys et al. · 2018 · Molecular Brain
Simulated Prosthetic Vision: The Benefits of Computer‐Based Object Recognition and Localization
Marc J.‐M. Macé, Valérian Guivarch, Grégoire Denis, Christophe Jouffrais · 2015 · Artificial Organs
Electrical Stimulation of the Human Visual Cortex Preliminary Report
Andrew Talalla, Leo A. Bullara, Robert H. Pudenz · 1974 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Current Status of Artificial Vision by Electrocortical Stimulation
John P. Girvin · 1988 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Psi, statistics, and society
J. Utts · 1987 · Behavioral and Brain Sciences
A novel interface for cortical columnar neuromodulation with multipoint infrared neural stimulation
Feiyan Tian, Ying Zhang, Kenneth E. Schriver, Jia Ming Hu, Anna Wang Roe · 2024 · Nature Communications
Rehabilitation regimes based upon psychophysical studies of prosthetic vision
Spencer C. Chen, Gregg Jorgen Suaning, John W. Morley, Nigel Hamilton Lovell · 2009 · Journal of Neural Engineering
Functional electrical stimulation on paraplegic patients
Helmut Kern · 2014 · European Journal of Translational Myology
Fabrication of large arrays of cortical electrodes for use in man
Gregory F. Klomp, M. V. B. Womack, Wm. H. Dobelle · 1977 · Journal of Biomedical Materials Research
Rules governing perception of multiple phosphenes by human observers
Bosking, William, Foster, Brett, Sun, Ping, Beauchamp, Mike, Yoshor, Daniel · 2018
Visual cortical prosthesis: an electrical perspective
Léo Pio‐Lopez, Romanos Poulkouras, Damien Depannemaecker · 2021 · Journal of Medical Engineering & Technology
A Wearable Real-Time System for Simultaneous Wireless Power and Data Transmission to Cortical Visual Prosthesis
Gian Luca Barbruni, Francesca Rodino, Paolo Motto Ros, Danilo Demarchi, Diego Ghezzi, Sandro Carrara · 2024 · IEEE Transactions on Biomedical Circuits and Systems
Implantation of a newly developed direct optic nerve electrode device for artificial vision in rabbits
Hirokazu Sakaguchi, Motohiro Kamei, Kentaro Nishida, Yasuo Terasawa, Takashi Fujikado, Motoki Ozawa, Kohji Nishida · 2012 · Journal of Artificial Organs
Life of Pt and Pt−Ir stimulating electrodes in neurological prostheses
P. E. K. Donaldson, Nick Donaldson, Giles Skey Brindley · 1985 · Medical & Biological Engineering & Computing
Ethical Considerations for Volunteer Recruitment of Visual Prosthesis Trials
Yu Xing Xia, Qiushi Ren · 2012 · Science and Engineering Ethics
Artificial Visual Information Produced by Retinal Prostheses
Sein Kim, Hyeonhee Roh, Maesoon Im · 2022 · Frontiers in Cellular Neuroscience
Evidence for roles of the activating function in electric stimulation
Stephen B. Knisley · 2000 · IEEE Transactions on Biomedical Engineering
Postmortem investigation of a human cortical visual prosthesis that was implanted for 36 years
Towle, Vernon L, Pytel, Peter, Lane, Frank, Plass, John, Frim, David M, Troyk, Philip R · 2020 · Journal of Neural Engineering