Cited by 1,911Stroke Rehabilitation and RecoveryMotor Control and AdaptationTranscranial Magnetic Stimulation Studies

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct

Nudo, Randolph J., Wise, Birute M., SiFuentes, Frank, Milliken, Garrett W.·1996·Science

Open this paper in CoChat — free account

Abstract

Substantial functional reorganization takes place in the motor cortex of adult primates after a focal ischemic infarct, as might occur in stroke. A subtotal lesion confined to a small portion of the representation of one hand was previously shown to result in a further loss of hand territory in the adjacent, undamaged cortex of adult squirrel monkeys. In the present study, retraining of skilled hand use after similar infarcts resulted in prevention of the loss of hand territory adjacent to the infarct. In some instances, the hand representations expanded into regions formerly occupied by representations of the elbow and shoulder. Functional reorganization in the undamaged motor cortex was accompanied by behavioral recovery of skilled hand function. These results suggest that, after local damage to the motor cortex, rehabilitative training can shape subsequent reorganization in the adjacent intact cortex, and that the undamaged motor cortex may play an important role in motor recovery.

Integrity signals

Registry

Crossref · 10.1126/science.272.5269.1791

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Functional MRI evidence for adult motor cortex plasticity during motor skill learning
Kami, A., Meyer, G., Jezzard, P., Adams, M. M., Turner, R., & Ungerleider, L. G. (1995) · Nature · doi:10.1038/377155a0 · Cited by 1,883
Technique to improve chronic motor deficit after stroke.
Taub, E., Miller, N. E., Novack, T. A., Cook, E. W., Fleming, W. C., Nepomuceno, C., Connell, J., & Crago, J. E. (1993) · PubMed · Cited by 1,557
Use-dependent alterations of movement representations in primary motor cortex of adult squirrel monkeys
Nudo, R. J., Milliken, G. W., Jenkins, W., & Merzenich, M. M. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00785.1996 · Cited by 1,416
The functional anatomy of motor recovery after stroke in humans: A study with positron emission tomography
Chollet, F., Piero, V. D., Wise, R. J. S., Brooks, D. J., Dolan, R. J., & Frackowiak, R. S. J. (1991) · Annals of Neurology · doi:10.1002/ana.410290112 · Cited by 1,096
Massive Cortical Reorganization After Sensory Deafferentation in Adult Macaques
Pons, T. P., Garraghty, P. E., Ommaya, A. K., Kaas, J. H., Taub, E., & Mishkin, M. (1991) · Science · doi:10.1126/science.1843843 · Cited by 1,081
THE RESTORATION OF MOTOR FUNCTION FOLLOWING HEMIPLEGIA IN MAN
Twitchell, T. E. (1951) · Brain · doi:10.1093/brain/74.4.443 · Cited by 942
Plasticity of Sensory and Motor Maps in Adult Mammals
Kaas, J. H. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.001033 · Cited by 913
Modulation of Cortical Motor Output Maps During Development of Implicit and Explicit Knowledge
Pascual‐Leone, Á., Grafman, J. H., & Hallett, M. (1994) · Science · doi:10.1126/science.8122113 · Cited by 745
Reorganization of movement representations in primary motor cortex following focal ischemic infarcts in adult squirrel monkeys
Nudo, R. J., & Milliken, G. W. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.75.5.2144 · Cited by 715
Reorganization of Movement Representations in Primary Motor Cortex Following Focal Ischemic Infarcts in Adult Squirrel Monkeys
Simonsen, C. (1998) · Neurology Report · doi:10.1097/01253086-199822020-00019 · Cited by 610

Show all 33 references

Research works printed but not linked: 7

BACHYRITA P, RECOVERY FUNCTION TH: 225 (1980).
BLACK P, OUTCOME SEVERE DAMAG: 65 (1975).
BLACK P, T AM NEUROL ASSOC 95, 207 (1970).
BUCY P.C., PRECENTRAL MOTOR COR: 353 (1944).
GOWLAND C, STROKE REHABILITATIO: 217 (1987).
NUDO R.J., SOC NEUR ABSTR 21, 517 (1995).
TRAVIS A.M., AM J PHYS MED 35, 273 (1956).

Sorted by citations

Items 801–900 of 1,000

Intracisternal Antisense Oligonucleotide to Growth Associated Protein-43 Blocks the Recovery-Promoting Effects of Basic Fibroblast Growth Factor after Focal Stroke
Kawamata, T., Ren, J., Cha, J.-H. J., & Finklestein, S. P. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7101 · Cited by 35
Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exercise
Kim, D. Y., Park, S., Lee, S.-U., Choi, D.-H., Park, H., Paek, S. H., Shin, H. Y., Kim, E., Park, S., & Lim, J. H. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.02.016 · Cited by 34
Some Key Problems for Robot-Assisted Movement Therapy Research: A Perspective from the University of California at Irvine
Reinkensmeyer, D. J., Galvez, J. A., Marchal–Crespo, L., Wolbrecht, E. T., & Bobrow, J. E. (2007) · International Conference on Rehabilitation Robotics · doi:10.1109/icorr.2007.4428547 · Cited by 34
Role of neuroimaging in promoting long‐term recovery from ischemic stroke
Seitz, R. J., & Donnan, G. A. (2010) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22315 · Cited by 34
Improvement of Upper Extremity Deficit after Constraint-Induced Movement Therapy Combined with and without Preconditioning Stimulation Using Dual-hemisphere Transcranial Direct Current Stimulation and Peripheral Neuromuscular Stimulation in Chronic Stroke Patients: A Pilot Randomized Controlled Trial
Takebayashi, T., Takahashi, K., Moriwaki, M., Sakamoto, T., & Domen, K. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00568 · Cited by 34
Ischemic Stroke in Pontine and Corona Radiata: Location Specific Impairment of Neural Network Investigated With Resting State fMRI
Jiang, C., Yi, L., Cai, S., & Zhang, L. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00575 · Cited by 35
Broca’s Area: Rethinking Classical Concepts From a Neuroscience Perspective
Burns, M. S., & Fahy, J. K. (2010) · Topics in Stroke Rehabilitation · doi:10.1310/tsr1706-401 · Cited by 35
Changes in cerebral activity after decreased upper-limb hypertonus: an EMG-fMRI study
Manganotti, P., Acler, M., Formaggio, E., Avesani, M., Milanese, F., Baraldo, A., Storti, S. F., Gasparini, A., Cerini, R., Mucelli, R. P., et al. (2010) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2009.12.023 · Cited by 34
BMP-7 and excess glutamate: opposing effects on dendrite growth from cerebral cortical neurons in vitro.
Esquenazi, S., Monnerie, H., Kaplan, P., & le Roux, P. L. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7906 · Cited by 39
Loss of somatic sensation
Carey, L. M. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511545078.018 · Cited by 34
BCI-FES With Multimodal Feedback for Motor Recovery Poststroke
Remsik, A. B., van Kan, P. L. E., Gloe, S., Gjini, K., Williams, L. M., Nair, V. A., Caldera, K. E., Williams, J. C., & Prabhakaran, V. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.725715 · Cited by 33
Effects of Transcranial Direct Current Stimulation With Sensory Modulation on Stroke Motor Rehabilitation: A Randomized Controlled Trial
Koh, C., Lin, J., Jeng, J., Huang, S., & Hsieh, C. (2017) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2017.05.025 · Cited by 33
Dopamine in Motor Cortex Is Necessary for Skill Learning
Molina-Luna, K., Pekanovic, A., Hertler, B., Schubring-Giese, M., Rioult-Pedotti, M.-S., & Luft, A. R. (2009) · Cited by 33
Premotor Cortical-Cerebellar Reorganization in a Macaque Model of Primary Motor Cortical Lesion and Recovery
Yamamoto, T., Hayashi, T., Murata, Y., Ose, T., & Higo, N. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0077-19.2019 · Cited by 33
Bypassing stroke-damaged neural pathways via a neural interface induces targeted cortical adaptation
Kato, K., Sawada, M., & Nishimura, Y. (2019) · Nature Communications · doi:10.1038/s41467-019-12647-y · Cited by 33
Acoustic Startle Reflex in Patients With Chronic Stroke at Different Stages of Motor Recovery: A Pilot Study
Li, S., Chang, S., Francisco, G. E., & Verduzco‐Gutierrez, M. (2014) · Topics in Stroke Rehabilitation · doi:10.1310/tsr2104-358 · Cited by 33
The role of auditory feedback in music-supported stroke rehabilitation: A single-blinded randomised controlled intervention
van Vugt, F. T., Kafczyk, T., Kuhn, W., Rollnik, J. D., Tillmann, B., & ALTENMÜLLER, E. O. (2016) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-150588 · Cited by 33
Brain plasticity and vagus nerve stimulation
Keute, M., & Gharabaghi, A. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102876 · Cited by 32
Movement-related event-related desynchronization in neuropsychiatric disorders
Leocani, L., & Comı, G. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)59023-5 · Cited by 31
Cortical networks subserving upper limb movements in primates.
Kaas, J. H., Stepniewska, I., & Gharbawie, O. A. (2012) · PubMed · Cited by 32
Challenge of Neurorehabilitation for Cerebellar Degenerative Diseases
Miyai, I. (2011) · The Cerebellum · doi:10.1007/s12311-011-0327-5 · Cited by 32
Forced use after TBI: promoting plasticity and function through practice
Page, S. J. (2003) · Brain Injury · doi:10.1080/0269905031000107160 · Cited by 32
Using a Multi-Task Adaptive VR System for Upper Limb Rehabilitation in the Acute Phase of Stroke
Cameirão, M. S., Badia, S. B. I., Duarte, E., & Verschure, P. F. M. J. (2008) · International Conference on Virtual Rehabilitation · doi:10.1109/icvr.2008.4625112 · Cited by 32
Parallel Cortical Networks Formed by Modular Organization of Primary Motor Cortex Outputs
Hamadjida, A., Dea, M. K., Deffeyes, J. E., Quessy, S., & Dancause, N. (2016) · Current Biology · doi:10.1016/j.cub.2016.04.068 · Cited by 33
Dexamphetamine treatment in stroke
Long, D., & Young, J. (2003) · QJM · doi:10.1093/qjmed/hcg113 · Cited by 32
Somesthetic, Visual, and Auditory Feedback and Their Interactions Applied to Upper Limb Neurorehabilitation Technology: A Narrative Review to Facilitate Contextualization of Knowledge
Proulx, C. E., Jean, M. T. L., Higgins, J., Gagnon, D. H., & Dancause, N. (2022) · Frontiers in Rehabilitation Sciences · doi:10.3389/fresc.2022.789479 · Cited by 33
Plasticity of Adult Sensorimotor System in Severe Brain Infarcts: Challenges and Opportunities
Sterr, A., & Conforto, A. B. (2012) · Neural Plasticity · doi:10.1155/2012/970136 · Cited by 31
Corticospinal Facilitation Following Prolonged Proprioceptive Stimulation by Means of Passive Wrist Movement
Macé, M. J. ‐., Levin, O., Alaerts, K., Rothwell, J. C., & Swinnen, S. P. (2008) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0b013e31817da170 · Cited by 31
Combined real-time fMRI and real time fNIRS brain computer interface (BCI): Training of volitional wrist extension after stroke, a case series pilot study
Matarasso, A. K., Rieke, J. D., White, K. D., Yusufali, M. M., & Daly, J. J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250431 · Cited by 34
Central nervous system physiology
Rothwell, J. C., Antal, A., Burke, D. J., Carlsen, A. N., Georgiev, D., Jahanshahi, M., Sternad, D., Valls‐Solé, J., & Ziemann, U. (2021) · Clinical Neurophysiology · doi:10.1016/j.clinph.2021.09.013 · Cited by 34
Anti-kindling achieved by stimulation targeting slow synaptic dynamics
Tass, P. A., & Hauptmann, C. (2009) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2009-0484 · Cited by 31
Physiotherapy after stroke in Ireland: a qualitative insight into the patients' and physiotherapists' experience
Galvin, R., Cusack, T., & Stokes, E. (2009) · International Journal of Rehabilitation Research · doi:10.1097/mrr.0b013e32832b083c · Cited by 31
Gadd45b Mediates Axonal Plasticity and Subsequent Functional Recovery After Experimental Stroke in Rats
Liu, B., Li, L., Tan, X., Zhang, Y., Jiang, Y., He, G., Chen, Q., & Li, C. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8909-0 · Cited by 31
Altered connectivity patterns among resting state networks in patients with ischemic white matter lesions
Ding, J., Ding, X., Hua, B., Xiong, X., Wen, Y., Ding, Z., Wang, Q., & Thompson, P. M. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9793-9 · Cited by 30
Degeneration, Trophic Interactions, and Repair of Severed Axons: A Reconsideration of Some Common Assumptions
Bittner, G. D., Schallert, T. J., & Peduzzi, J. D. (2000) · The Neuroscientist · doi:10.1177/107385840000600207 · Cited by 31
Enlargement of cortical vibrissa representation in the surround of an ischemic cortical lesion
Schiene, K., Staiger, J. F., Bruehl, C., & Witte, O. W. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00292-5 · Cited by 31
Assessing and inducing neuroplasticity with transcranial magnetic stimulation and robotics for motor function.
O'Malley, M., Ro, T., & Levin, H. (2006) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2006.08.332 · Cited by 32
Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation
Moon, L. D. F., Leasure, J. L., Gage, F. H., & Bunge, M. B. (2006) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2006-00336 · Cited by 31
An introduction to functional magnetic resonance imaging of the brain
Matthews, P. M. (2001) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780192630711.003.0001 · Cited by 30
A New Model of Localized Ischemia in Rat Somatosensory Cortex Produced by Cortical Compression
Watanabe, S., Hoffman, J. R., Craik, R. L., Hand, P. J., Croul, S. E., Reivich, M., & Greenberg, J. H. (2001) · Stroke · doi:10.1161/hs1101.097384 · Cited by 31
Motor control testing of upper limb function after botulinum toxin injection: A case study
Hurvitz, E. A., Conti, G. E., Flansburg, E. L., & Brown, S. H. (2000) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2000.6293 · Cited by 31
Trunk Robot Rehabilitation Training with Active Stepping Reorganizes and Enriches Trunk Motor Cortex Representations in Spinal Transected Rats
Oza, C. S., & Giszter, S. F. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4366-14.2015 · Cited by 32
Post-stroke protection from maladaptive effects of learning with the non-paretic forelimb by bimanual home cage experience in C57BL/6 mice
Kerr, A. L., Wolke, M. L., Bell, J. A., & Jones, T. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.062 · Cited by 33
Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats
Adkins, D. L., Ferguson, L. A., Lance, S., Pevtsov, A., McDonough, K., Stamschror, J. D., Jones, T. A., & Kozlowski, D. A. (2015) · Neurorehabilitation and neural repair · doi:10.1177/1545968315576577 · Cited by 30
Coordinated increase of reliable cortical and striatal ensemble activations during recovery after stroke
Guo, L. T., Kondapavulur, S., Lemke, S. M., Won, S. J., & Ganguly, K. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109370 · Cited by 32
Task-specific modulation of corticospinal neuron activity during motor learning in mice
Serradj, N., Marino, F., Moreno-López, Y., Bernstein, A., Agger, S., Soliman, M., Sloan, A. M., & Hollis, E. R., II (2023) · Nature Communications · doi:10.1038/s41467-023-38418-4 · Cited by 41
Recovery of hand function through mental practice: A study protocol
Ietswaart, M., Johnston, M., Dijkerman, H. C., Scott, C. L., Joice, S., Hamilton, S., & MacWalter, R. S. (2006) · BMC Neurology · doi:10.1186/1471-2377-6-39 · Cited by 31
Statistical Signal Processing and the Motor Cortex
Brockwell, A., Kass, R. E., & Schwartz, A. B. (2007) · Proceedings of the IEEE · doi:10.1109/jproc.2007.894703 · Cited by 30
Synapse Loss and Regeneration: A Mechanism for Functional Decline and Recovery after Cerebral Ischemia?
Hasbani, M. J., Underhill, S. M., de Erausquin, G. A., & Goldberg, M. P. (2000) · The Neuroscientist · doi:10.1177/107385840000600208 · Cited by 30
Study on the sEMG Driven Upper Limb Exoskeleton Rehabilitation Device in Bilateral Rehabilitation
Pang, M., Guo, S., & Song, Z. (2012) · Journal of Robotics and Mechatronics · doi:10.20965/jrm.2012.p0585 · Cited by 30
Axonal remodeling in the corticospinal tract after stroke: how does rehabilitative training modulate it?
Okabe, N., Narita, K., & Miyamoto, O. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.200792 · Cited by 30
Neuroplasticity subserving the operation of brain–machine interfaces
Oweiss, K. G., & Badreldin, I. S. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.05.001 · Cited by 33
Phase II Randomized Controlled Trial of Constraint-Induced Movement Therapy in Multiple Sclerosis. Part 2: Effect on White Matter Integrity
Barghi, A., Allendorfer, J. B., Taub, E., Womble, B., Hicks, J. M., Uswatte, G., Szaflarski, J. P., & Mark, V. W. (2018) · Neurorehabilitation and neural repair · doi:10.1177/1545968317753073 · Cited by 31
Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice
Houlton, J., Zhou, L. Y. Y., Barwick, D., Gowing, E. K., & Clarkson, A. N. (2019) · Neural Plasticity · doi:10.1155/2019/1460890 · Cited by 31
Constraint-Induced Movement Therapy
Barghi, A., Mark, V. W., & Taub, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805298-3.00015-3 · Cited by 30
At the interface: convergence of neural regeneration and neural prostheses for restoration of function.
Grill, W. M., McDonald, J. W., Peckham, P. H., Heetderks, W., Kocsis, J. D., & Weinrich, M. (2001) · PubMed · Cited by 30
Facilitation of motor evoked potentials after repetitive voluntary hand movements depends on the type of motor activity
Hauptmann, B., Skrotzki, A., & Hummelsheim, H. (1997) · Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control · doi:10.1016/s0924-980x(97)00031-3 · Cited by 30
Hand rehabilitation based on the RobHand exoskeleton in stroke patients: A case series study
Barría, P., Matías Riquelme, O., Reppich, H., Cisnal, A., Fraile, J. C., Turiel, J. P., Sierra, D., Aguilar, R., Andrade, A., & Núñez-Espinosa, C. A. (2023) · Frontiers in Robotics and AI · doi:10.3389/frobt.2023.1146018 · Cited by 29
Exoskeleton-Robot Assisted Therapy in Stroke Patients: A Lesion Mapping Study
Cerasa, A., Pignolo, L., Gramigna, V., Serra, S., Olivadese, G., Rocca, F., Perrotta, P., Dolce, G., Quattrone, A., & Tonin, P. (2018) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2018.00044 · Cited by 30
Exciting recovery
Field-Fote, E. C. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2014.12.006 · Cited by 29
Neurochemical balance and inhibition at the subacute stage after stroke
Cirillo, J., Mooney, R. A., Ackerley, S., Barber, P. A., Borges, V. M., Clarkson, A. N., Mangold, C., Ren, A., Smith, M., Stinear, C. M., et al. (2020) · Journal of Neurophysiology · doi:10.1152/jn.00561.2019 · Cited by 31
Wearable myoelectric interface enables high‐dose, home‐based training in severely impaired chronic stroke survivors
Hung, N., Paul, V., Prakash, P., Kovach, T., Tacy, G., Tomic, G., Park, S., Jacobson, T., Jampol, A., Patel, P., et al. (2021) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51442 · Cited by 29
New tools for shaping plasticity to enhance recovery after stroke
Motolese, F., Capone, F., & Lazzaro, V. D. (2022) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819410-2.00016-3 · Cited by 34
Plasticity of cerebral functions
Nudo, R. J., & McNeal, D. W. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52901-5.00002-2 · Cited by 31
A paradigm shift in neurorehabilitation
Nadeau, S. E. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(02)00044-3 · Cited by 29
Effectiveness and neural mechanisms associated with tDCS delivered to premotor cortex in stroke rehabilitation: study protocol for a randomized controlled trial
Plow, E. B., Cunningham, D. A., Beall, E. B., Jones, S., Wyant, A., Bonnett, C. E., Yue, G. H., Lowe, M. J., Wang, X., Sakaie, K., et al. (2013) · Trials · doi:10.1186/1745-6215-14-331 · Cited by 30
Same Intervention–Different Reorganization
Carey, L. M., Abbott, D. F., Lamp, G., Puce, A., Seitz, R. J., & Donnan, G. A. (2016) · Neurorehabilitation and neural repair · doi:10.1177/1545968316653836 · Cited by 29
Process of the Functional Reorganization of the Cortical Centers for Movement in GBM Patients: fMRI Study
Majos, A., Bryszewski, B., Kośla, K., Pfaifer, L., Jaskólski, D. J., & Stefańczyk, L. (2015) · Clinical Neuroradiology · doi:10.1007/s00062-015-0398-7 · Cited by 29
Compensatory Relearning Following Stroke: Cellular and Plasticity Mechanisms in Rodents
Balbinot, G. C., & Schuch, C. P. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.01023 · Cited by 30
Learning-based Animal Models: Task-specific Focal Hand Dystonia
Byl, N. N. (2007) · ILAR Journal · doi:10.1093/ilar.48.4.411 · Cited by 29
The Control of Movement Following Traumatic Brain Injury
Kozlowski, D. A., Leasure, J. L., & Schallert, T. J. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110005 · Cited by 29
Advances in neurocognitive rehabilitation research from 1992 to 2017: The ascension of neural plasticity.
Crosson, B., Hampstead, B. M., Krishnamurthy, L. C., Krishnamurthy, V., McGregor, K., Nocera, J. R., Roberts, S. R., Rodriguez, A. D., & Tran, S. M. (2017) · Neuropsychology · doi:10.1037/neu0000396 · Cited by 32
Effects of Home-Based Robotic Therapy Involving the Single-Joint Hybrid Assistive Limb Robotic Suit in the Chronic Phase of Stroke: A Pilot Study
Hyakutake, K., Morishita, T., Saita, K., Fukuda, H., Shiota, E., Higaki, Y., Inoue, T., & Uehara, Y. (2019) · BioMed Research International · doi:10.1155/2019/5462694 · Cited by 29
Early onset of forced impaired forelimb use causes recovery of forelimb skilled motor function but no effect on gross sensory-motor function after capsular hemorrhage in rats
Ishida, A., Tamakoshi, K., Hamakawa, M., Shimada, H., Nakashima, H., Masuda, T., Hida, H., & Ishida, K. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.06.036 · Cited by 27
La stimulation magnétique transcrânienne (SMT) dans la recherche fondamentale et clinique en neuroscience
Valero‐Cabré, A., Pascual‐Leone, Á., & Coubard, O. A. (2011) · Revue Neurologique · doi:10.1016/j.neurol.2010.10.013 · Cited by 46
Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke
Inácio, A. R. L., Ruscher, K., & Wieloch, T. W. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.09.015 · Cited by 28
Experience: a double-edged sword for restorative neural plasticity after brain damage
Allred, R. P., & Jones, T. A. (2008) · Future Neurology · doi:10.2217/14796708.3.2.189 · Cited by 28
Ministrokes in Channelrhodopsin-2 Transgenic Mice Reveal Widespread Deficits in Motor Output Despite Maintenance of Cortical Neuronal Excitability
Anenberg, E., Arstikaitis, P., Niitsu, Y., Harrison, T. C., Boyd, J. D., Hilton, B. J., Tetzlaff, W., & Murphy, T. H. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1442-13.2014 · Cited by 27
Diffusion tensor imaging in the study of language and aphasia
Geva, S., Correia, M., & Warburton, E. A. (2011) · Aphasiology · doi:10.1080/02687038.2010.534803 · Cited by 28
Maladaptive change of body representation in the brain after damage to central or peripheral nervous system
Oouchida, Y., Sudo, T., Inamura, T., Tanaka, N., Ohki, Y., & Izumi, S. (2015) · Neuroscience Research · doi:10.1016/j.neures.2015.12.015 · Cited by 29
Frequency‐specific functional connectivity related to the rehabilitation task of stroke patients
Lu, K., Xu, G., Li, W., Huo, C., Liu, Q., Lv, Z., Wang, Y., Li, Z., & Fan, Y. (2019) · Medical Physics · doi:10.1002/mp.13398 · Cited by 28
The Neurobiology of Language Recovery in Aphasia
Thompson, C. K. (2000) · Brain and Language · doi:10.1006/brln.1999.2260 · Cited by 28
Functional Imaging of Stroke Recovery: An Ecological Review from a Neural Network Perspective with an Emphasis on Motor Systems
Ween, J. E. (2008) · Journal of Neuroimaging · doi:10.1111/j.1552-6569.2007.00180.x · Cited by 30
Fundamentals of cognitive rehabilitation
Mateer, C. A. (2005) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198526544.003.0003 · Cited by 28
Evolution, biomechanics, and neurobiology converge to explain selective finger motor control
Xu, J., Mawase, F., & Schieber, M. H. (2024) · Physiological Reviews · doi:10.1152/physrev.00030.2023 · Cited by 32
Functional Preservation and Reorganization of Brain during Motor Imagery in Patients with Incomplete Spinal Cord Injury: A Pilot fMRI Study
Chen, X., Wan, L., Qin, W., Zheng, W., Qi, Z., Chen, N., & Li, K. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00046 · Cited by 27
Rehabilitation robotics for the upper extremity: review with new directions for orthopaedic disorders
Hakim, R. M., Tunis, B. G., & Ross, M. D. (2016) · Disability and Rehabilitation Assistive Technology · doi:10.1080/17483107.2016.1269211 · Cited by 27
Recovery of consolidation after sleep following stroke—interaction of slow waves, spindles, and GABA
Kim, J., Guo, L. T., Hishinuma, A. K., Lemke, S. M., Ramanathan, D., Won, S. J., & Ganguly, K. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110426 · Cited by 29
Effects of Computer-Aided Interlimb Force Coupling Training on Paretic Hand and Arm Motor Control following Chronic Stroke: A Randomized Controlled Trial
Lin, C., Chou, L., Luo, H.-J., Tsai, P., Lieu, F., Chiang, S., & Sung, W.-H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131048 · Cited by 27
Motor maps and the cortical control of movement
Harrison, T. C., & Murphy, T. H. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.08.018 · Cited by 28
Long-term changes of GABAergic function in the sensorimotor cortex of amputees
Capaday, C., Richardson, M. P., Rothwell, J. C., & Brooks, D. J. (2000) · Experimental Brain Research · doi:10.1007/s002210000477 · Cited by 27
Neuroimaging of recovery from aphasia
Cappa, S. F. (2000) · Neuropsychological Rehabilitation · doi:10.1080/096020100389192 · Cited by 27
The Neuroethology of Vocal Communication: Perception and Cognition
Gentner, T. Q., & Margoliash, D. (2006) · Springer eBooks · doi:10.1007/0-387-22762-8_7 · Cited by 28
Stroke Research in the Modern Era: Images versus Dogmas
Baron, J. (2005) · Cerebrovascular Diseases · doi:10.1159/000087199 · Cited by 27
Factors Contributing to Motor Impairment and Recovery after Stroke
Heddings, A., Friel, K. M., Plautz, E. J., Barbay, S., & Nudo, R. J. (2000) · Neurorehabilitation and neural repair · doi:10.1177/154596830001400406 · Cited by 27
Visual network activation in recovery from sensorimotor stroke.
Seitz, R. J., Knorr, U., Azari, N. P., Herzog, H. R., & Freund, H. (1999) · PubMed · Cited by 27
Multidimensional Phase I Dose Ranging Trials for Stroke Recovery Interventions: Key Challenges and How to Address Them
Dalton, E. J., Churilov, L. P., Lannin, N. A., Corbett, D., Campbell, B. C. V., & Hayward, K. S. (2021) · Neurorehabilitation and neural repair · doi:10.1177/15459683211019362 · Cited by 26
Effects of rehabilitative training on recovery of hand motor function: A review of animal studies
Higo, N. (2013) · Neuroscience Research · doi:10.1016/j.neures.2013.09.008 · Cited by 26
Intensité et rééducation motrice dans la parésie spastique
Meimoun, M., Bayle, N., Baude, M., & Graciès, J. (2015) · Revue Neurologique · doi:10.1016/j.neurol.2014.09.011 · Cited by 28
Body-Machine Interfaces after Spinal Cord Injury: Rehabilitation and Brain Plasticity
Seáñez, I., Pierella, C., Farshchiansadegh, A., Thorp, E. B., Wang, X., Parrish, T. B., & Mussa-Ivaldi, F. A. (2016) · Brain Sciences · doi:10.3390/brainsci6040061 · Cited by 26

Authors: Nudo, R. J., Wise, B. M., SiFuentes, F., & Milliken, G. W.
Affiliations: The University of Texas Health Science Center at Houston (US)
Corresponding author: Nudo, Randolph J.
Milliken, Garrett W.
ORCID: Nudo, Randolph J.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 1996-06-21
Volume: 272
Issue: 5269
Pages: 1791-1794
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.272.5269.1791
OpenAlex: W2038514344
Cited by: 1,911
References: 33
Citations by year: 2026: 34 · 2025: 38 · 2024: 35 · 2023: 51 · 2022: 61 · 2021: 56 · 2020: 34 · 2019: 59 · 2018: 46 · 2017: 71 · 2016: 71 · 2015: 77 · 2014: 82 · 2013: 79 · 2012: 77
FWCI: 52.86
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r29ns027974-05)
National Institute of Neurological Disorders and Stroke (NS27974, NS30853)
Topics: Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords: motor cortex, functional reorganization, ischemic infarct, stroke, motor recovery, rehabilitative training, hand representation, squirrel monkey, cortical plasticity
MeSH terms: Animals, Brain Mapping, Cerebral Infarction, Brain Ischemia, Electric Stimulation, Hand, Male, Motor Cortex, Motor Skills, Neuronal Plasticity, Random Allocation, Saimiri

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks