The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Natural Behavior Polymorphism Due to a cGMP-Dependent Protein Kinase of Drosophila
Abstract
Naturally occuring polymorphisms in behavior are difficult to map genetically and thus are refractory to molecular characterization. An exception is the foraging gene ( for ), a gene that has two naturally occurring variants in Drosophila melanogaster food-search behavior: rover and sitter. Molecular mapping placed for mutations in the dg2 gene, which encodes a cyclic guanosine monophosphate (cGMP)–dependent protein kinase (PKG). Rovers had higher PKG activity than sitters, and transgenic sitters expressing a dg2 complementary DNA from rover showed transformation of behavior to rover. Thus, PKG levels affected food-search behavior, and natural variation in PKG activity accounted for a behavioral polymorphism.
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Metadata
- Authors
- Osborne, K. A., Robichon, A., Burgess, E., Butland, S., Shaw, R. A., Coulthard, A., Pereira, H. S., Greenspan, R. J., & Sokolowski, M. B.
- Venue
- Science
- Published
- 1997-08-08
- Volume
- 277
- Issue
- 5327
- Pages
- 834-836
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1976354663
- Cited by
- 536
- References
- 2
- FWCI
- 5.19
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
