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Cited by 241

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Transcriptional Coregulators in Development

Mannervik, Mattias, Nibu, Yutaka, Zhang, Hailan, Levine, Michael·1999·Science

Abstract

Small differences in the levels of an extracellular signaling molecule can specify cell fate during development. Threshold responses are often determined at the level of transcription. Cell-specific and spatially localized patterns of gene expression depend on combinations of sequence-specific activators and repressors that bind to extensive cis-regulatory regions. Different mechanisms for integrating this complex regulatory information are discussed, particularly the role of coregulatory proteins, which are recruited to the DNA template by sequence-specific transcription factors. Recent studies suggest that a growing set of coactivators and corepressors mediate communication between diverse upstream regulatory proteins and the core RNA polymerase II transcription complex.

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Crossref · 10.1126/science.284.5414.606

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Metadata

Authors
Mannervik, M., Nibu, Y., Zhang, H., & Levine, M.
Venue
Science
Published
1999-04-23
Volume
284
Issue
5414
Pages
606-609
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1986457767
Cited by
241
References
7
FWCI
10.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Transcriptional Coregulators in Development. https://app.cochat.ai/papers/10.1126/science.284.5414.606
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Mannervik, M., Nibu, Y., Zhang, H., & Levine, M. (1999). Transcriptional Coregulators in Development. Science. https://doi.org/10.1126/science.284.5414.606

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.