The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Infection of the SCID-hu Mouse by HIV-1
Abstract
SCID-hu mice with human fetal thymic or lymph node implants were inoculated with the cloned human immunodeficiency virus-1 isolate, HIV-1 JR-CSF . In a time- and dose-dependent fashion, viral replication spread within the human lymphoid organs. Combination immunohistochemistry and in situ hybridization revealed only viral RNA transcripts in most infected cells, but some cells had both detectable viral transcripts and viral protein. Infected cells were always more apparent in the medulla than in the cortex of the thymus. These studies demonstrate that an acute infection of human lymphoid organs with HIV-1 can be followed in the SCID-hu mouse.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Barré-Sinoussi, F., Chermann, J. C., Rey, F., Nugeyre, M. T., Chamaret, S., Gruest, J., Dauguet, C., Axler-Blin, C., Vézinet-Brun, F., Rouzioux, C., et al. (1983) · Science · doi:10.1126/science.6189183 · Cited by 7,038
Popovic, M., Sarngadharan, M. G., Read, E., & Gallo, R. C. (1984) · Science · doi:10.1126/science.6200935 · Cited by 3,535
Complete nucleotide sequence of the AIDS virus, HTLV-III
Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., et al. (1985) · Nature · doi:10.1038/313277a0 · Cited by 2,245
Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDS
Levy, J. A., Hoffman, A. D., Kramer, S. M., Landis, J. A., Shimabukuro, J. M., & Oshiro, L. S. (1984) · Science · doi:10.1126/science.6206563 · Cited by 1,436
McCune, J., Namikawa, R., Kaneshima, H., Shultz, L., Lieberman, M., & Weissman, I. (1988) · Science · doi:10.1126/science.241.4873.1632 · Cited by 1,406
Self-citationIsolation of a T-Lymphotropic Virus from Domestic Cats with an Immunodeficiency-Like Syndrome
Pedersen, N. C., Ho, E. W., Brown, M. L., & Yamamoto, J. K. (1987) · Science · doi:10.1126/science.3643650 · Cited by 1,027
Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques
Daniel, M. D., Letvin, N. L., King, N. W., Kannagi, M., Sehgal, P. K., Hunt, R. D., Kanki, P. J., Essex, M., & Desrosiers, R. C. (1985) · Science · doi:10.1126/science.3159089 · Cited by 920
Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms
Koyanagi, Y., Miles, S., Mitsuyasu, R. T., Merrill, J. E., Vinters, H. V., & Chen, I. S. Y. (1987) · Science · doi:10.1126/science.3646751 · Cited by 817
Shaw, G. M., Hahn, B. H., Arya, S. K., Groopman, J. E., Gallo, R. C., & Wong-Staal, F. (1984) · Science · doi:10.1126/science.6095449 · Cited by 633
Pathogenesis of lentivirus infections
Haase, A. T. (1986) · Nature · doi:10.1038/322130a0 · Cited by 566
Cited by
Hematopoiesis: a human perspective
Doulatov, S., Notta, F., Laurenti, E., & Dick, J. E. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.01.006 · Cited by 895
Brenchley, J. M., Hill, B. J., Ambrozak, D. R., Price, D. A., Guenaga, F. J., Casazza, J. P., Kuruppu, J., Yazdani, J., Migueles, S. A., Connors, M., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.3.1160-1168.2004 · Cited by 384
HIV induces thymus depletion in vivo
Bonyhadi, M. L., Rabin, L., Salimi, S., Brown, D. A., Kosek, J., McCune, J. M., & Kaneshima, H. (1993) · Nature · doi:10.1038/363728a0 · Cited by 379
Self-citationCurrent advances in humanized mouse models
Ito, R., Takahashi, T., Katano, I., & Ito, M. (2012) · Cellular & Molecular Immunology · doi:10.1038/cmi.2012.2 · Cited by 349
Animal models for HIV/AIDS research
Hatziioannou, T., & Evans, D. T. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2911 · Cited by 340
Metadata
- Authors
- Namikawa, R., Kaneshima, H., Lieberman, M., Weissman, I. L., & McCune, J. M.
- Venue
- Science
- Published
- 1988-12-23
- Volume
- 242
- Issue
- 4886
- Pages
- 1684-1686
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1969379511
- Cited by
- 366
- References
- 19
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Infection of the SCID-hu Mouse by HIV-1. https://app.cochat.ai/papers/10.1126/science.3201256
- The paper
- Namikawa, R., Kaneshima, H., Lieberman, M., Weissman, I. L., & McCune, J. M. (1988). Infection of the SCID-hu Mouse by HIV-1. Science. https://doi.org/10.1126/science.3201256
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.