A Receptor-Mediated Pathway for Cholesterol Homeostasis
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- Inhibition of PCSK9: A powerful weapon for achieving ideal LDL cholesterol levelsDaniel Howard Steinberg, Joseph Lee Witztum · 2009 · Proceedings of the National Academy of Sciences
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- Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and TherapyMichael Tran Duong, Ilya M. Nasrallah, David A. Wolk, Catherine C.Y. Chang, Ta‐Yuan Chang · 2021 · Frontiers in Aging Neuroscience
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- Curcumin suppresses expression of low‐density lipoprotein (LDL) receptor, leading to the inhibition of LDL‐induced activation of hepatic stellate cellsQiaohua Kang, Anping Chen · 2009 · British Journal of Pharmacology
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- Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient NeuronsBarbara Karten, Dennis E. Vance, Robert B. Campenot, Jean E. Vance · 2003 · Journal of Biological Chemistry
- Two Hepatic Enhancers, HCR.1 and HCR.2, Coordinate the Liver Expression of the Entire Human Apolipoprotein E/C-I/C-IV/C-II Gene ClusterCharles M. Allan, Stacy Taylor, John M. Taylor · 1997 · Journal of Biological Chemistry
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- The familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland.Ulla‐Maija Koivisto, Hannu Turtola, Katriina Aalto‐Setälä, Bert Top, Rune R. Frants, Petri T. Kovanen, A C Syvänen, KIMMO K. KONTULA · 1992 · Journal of Clinical Investigation
- Familial hypercholesterolemia in Brazil: Cascade screening program, clinical and genetic aspectsCinthia E. Jannes, Raul Dias Santos, Pãmela R.S. Silva, Luciana Turolla, Ana Carolina Moron Gagliardi, Júlia Daher Carneiro Marsiglia, Ana Paula Marte Chacra, Marcio Hiroshi Miname, Viviane Zorzanelli Rocha, Wilson Salgado Filho et al. · 2014 · Atherosclerosis
- Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptakeYang, Muhua, Liu, Weidong, Pellicane, Christina, Sahyoun, Christine, Joseph, Biny K., Gallo-Ebert, Christina, Donigan, Melissa, Pandya, Devanshi, Giordano, Caroline, Bata, Adam et al. · 2014 · Journal of Lipid Research
- The Role of Structure and Biophysical Properties in the Pleiotropic Effects of StatinsChristopher Murphy, Evelyne Deplazes, Charles G. Cranfield, Alvaro Garcia · 2020 · International Journal of Molecular Sciences
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- Cloning and regulation of hamster microsomal triglyceride transfer protein. The regulation is independent from that of other hepatic and intestinal proteins which participate in the transport of fatty acids and triglycerides.Mengjie Lin, CM Arbeeny, K. E. Bergquist, Bernadette K. Kienzle, David A. Gordon, John R. Wetterau · 1994 · Journal of Biological Chemistry
- Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cellsLalanne, Florent, Lambert, Gilles, Amar, Marcelo J.A., Chétiveaux, Maud, Zaïr, Yassine, Jarnoux, Anne-Laure, Ouguerram, Khadija, Friburg, José, Seidah, Nabil G., Brewer, H. Bryan et al. · 2005 · Journal of Lipid Research
- Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive HypercholesterolemiaNathan O. Stitziel, Sigrid W. Fouchier, Barbara Sjouke, Gina Marie Peloso, Alessa M. Moscoso, Paul Livermore Auer, Anuj Goel, Bruna Gigante, Timothy A. Barnes, Olle Melander et al. · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
- Selenium nanoparticles alleviate hyperlipidemia and vascular injury in ApoE-deficient mice by regulating cholesterol metabolism and reducing oxidative stressLeilei Guo, Junying Xiao, Haijuan Liu, Hongmei Liu · 2019 · Metallomics
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- Reducing saturated fat intake is associated with increased levels of LDL receptors on mononuclear cells in healthy men and womenVikkie A. Mustad, Terry D. Etherton, Allen D. Cooper, Andrea M. Mastro, Thomas A. Pearson, Satya S. Jonnalagadda, Penny M. Kris‐Etherton · 1997 · Journal of Lipid Research
- Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantationJ. Ryan Gunsalus, Deborah A. Brady, Sarah Coulter, Brian M. Gray, Albert S.B. Edge · 1997 · Nature Medicine
- Mechanisms by which saturated triacylglycerols elevate the plasma low density lipoprotein-cholesterol concentration in hamsters. Differential effects of fatty acid chain length.L A Woollett, David K. Spady, John M. Dietschy · 1989 · Journal of Clinical Investigation
- Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell cultureMayne, Janice, Dewpura, Thilina, Raymond, Angela, Bernier, Lise, Cousins, Marion, Ooi, Teik Chye, Davignon, Jean, Seidah, Nabil G, Mbikay, Majambu, Chrétien, Michel · 2011 · Clinical Chemistry
- Dietary fiber and lipidsT.A. Miettinen · 1987 · American Journal of Clinical Nutrition
- Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesisZhao, Lei, Chen, Yaxi, Tang, Renkuan, Chen, Yao, Li, Qing, Gong, Jianping, Huang, Ailong, Varghese, Zac, Moorhead, John F, Ruan, Xiong Z · 2011 · Journal of Gastroenterology and Hepatology
- Lycopene in atherosclerosis prevention: An integrated scheme of the potential mechanisms of action from cell culture studiesPaola Palozza, Nadia Parrone, Rossella E. Simone, Assunta Catalano · 2010 · Archives of Biochemistry and Biophysics
- Finnish type of low density lipoprotein receptor gene mutation (FH-Helsinki) deletes exons encoding the carboxy-terminal part of the receptor and creates an internalization-defective phenotype.Katriina Aalto‐Setälä, Eero Helve, Petri T. Kovanen, KIMMO K. KONTULA · 1989 · Journal of Clinical Investigation
- A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulationMark T. Mc Auley, Darren J. Wilkinson, Janette JL Jones, Thomas B. L. Kirkwood · 2012 · BMC Systems Biology
- Routes and mechanisms of post‐endosomal cholesterol trafficking: A story that never endsJie Luo, Luyi Jiang, Hongyuan Yang, Bao‐Liang Song · 2017 · Traffic
- Endocytic and Transcytotic Processes in Villous Syncytiotrophoblast: Role in Nutrient Transport to the Human FetusRenate Fuchs, Isabella Ellinger · 2004 · Traffic
- Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid raftsYoshiko Ohno‐Iwashita, Yukiko Shimada, A.Abdul Waheed, Masami Hayashi, Mitsushi Inomata, Megumi Nakamura, Mikako Maruya, Shintaro Iwashita · 2003 · Anaerobe
- Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivoRobert J. Schmidt, Thomas P. Beyer, William R. Bensch, Yuewei Qian, Aiming Lin, Mark C. Kowala, William E. Alborn, Robert J. Konrad, Guoqing Cao · 2008 · Biochemical and Biophysical Research Communications
- Effect of chitosan supplementation on antitubercular drugs-induced hepatotoxicity in ratsSethumadhavan Santhosh, T. Sini, R. Anandan, Paruthapara Thomas Mathew · 2005 · Toxicology
- Chicken Oocytes and Somatic Cells Express Different Splice Variants of a Multifunctional ReceptorHideaki Bujo, Ken A. Lindstedt, Marcela Hermann, Lourdes Mola Dalmau, Johannes Nimpf, Wolfgang J. Schneider · 1995 · Journal of Biological Chemistry
- A single-base substitution in the proximal Sp1 site of the human low density lipoprotein receptor promoter as a cause of heterozygous familial hypercholesterolemia.Ulla‐Maija Koivisto, Jorma J. Palvimo, Olli A. Jänne, Kimmo Kontula · 1994 · Proceedings of the National Academy of Sciences
- Atorvastatin: An Effective Lipid-Modifying Agent in Familial HypercholesterolemiaAdrian David Marais, Jean Catherine Firth, Mary E. Bateman, P. J. Byrnes, Candice Martens, J. Mountney · 1997 · Arteriosclerosis Thrombosis and Vascular Biology
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- Clinical Efficacy and Safety of Alirocumab After Acute Coronary Syndrome According to Achieved Level of Low-Density Lipoprotein CholesterolGregory G. Schwartz, Philippe Gabríel Steg, Deepak L. Bhatt, Vera Bittner, Rafael Díaz, Shaun G. Goodman, J. Wouter Jukema, Yong-Un Kim, Qian H Li, Garen Z. Manvelian et al. · 2021 · Circulation
- Identification of Genes Related to Growth and Lipid Deposition from Transcriptome Profiles of Pig Muscle TissueZhixiu Wang, Qinggang Li, Yangzom Chamba, Bo Zhang, Peng Shang, Hao Zhang, Changxin Wu · 2015 · PLoS ONE
- A CD36-related Transmembrane Protein Is Coordinated with an Intracellular Lipid-binding Protein in Selective Carotenoid Transport for Cocoon ColorationTakashi Sakudoh, Tetsuya Iizuka, Junko Narukawa, Hideki Sezutsu, Isao Kobayashi, Seigo Kuwazaki, Yutaka Banno, Akitoshi Kitamura, Hiromu Sugiyama, Naoko Takada et al. · 2010 · Journal of Biological Chemistry
- Drosophila NPC1b Promotes an Early Step in Sterol Absorption from the Midgut EpitheliumStephen P. Voght, Megan L. Fluegel, Laurie A. Andrews, Leo J. Pallanck · 2007 · Cell Metabolism
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- Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburideThomas J.F. Nieland, Angeliki Chroni, Michael L. Fitzgerald, Zoltan Maliga, Vassilis I. Zannis, Tomas L. Kirchhausen, Monty Krieger · 2004 · Journal of Lipid Research
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- Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J miceCristobal L. Miranda, Valerie D. Elias, Joshua J. Hay, Jaewoo Choi, Ralph L. Reed, Jan Frederik Stevens · 2016 · Archives of Biochemistry and Biophysics
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- Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2Jiangqing Dong, Ximing Du, Huan Wang, Jue Wang, Chang Lu, Xiang Chen, Zhiwen Zhu, Zhipu Luo, Li Yu, Andrew John Brown et al. · 2019 · Nature Communications
- Expanded-dose simvastatin is effective in homozygous familial hypercholesterolaemiaFrederick Johan Raal, Gillian J. Pilcher, D. Roger Illingworth, Anuradha S. Pappu, Evan A. Stein, Peter M. Laskarzewski, Yale Mitchel, Michael R. Melino · 1997 · Atherosclerosis
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