The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Rapid development of a DNA vaccine for Zika virus
Open accessAbstract
A DNA vaccine candidate for Zika: The ongoing Zika epidemic in the Americas and the Caribbean urgently needs a protective vaccine. Two DNA vaccines composed of the genes that encode the structural premembrane and envelope proteins of Zika virus have been tested in monkeys. Dowd et al. show that two doses of vaccine given intramuscularly completely protected 17 of 18 animals against Zika virus challenge. A single low dose of vaccine was not protective but did reduce viral loads. Protection correlated with serum antibody neutralizing activity. Phase I clinical trials testing these vaccines are already ongoing. Science , this issue p. 237
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Guzman, M. G., Alvarez, M., & Halstead, S. B. (2013) · Archives of Virology · doi:10.1007/s00705-013-1645-3 · Cited by 738
Prospects for a dengue virus vaccine
Whitehead, S. S., Blaney, J. E., Durbin, A. P., & Murphy, B. R. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1690 · Cited by 623
Vaccine protection against Zika virus from Brazil
Larocca, R. A., Abbink, P., Peron, J. P. S., de A. Zanotto, P. M., Iampietro, M. J., Badamchi-Zadeh, A., Boyd, M., Ng’ang’a, D., Kirilova, M., Nityanandam, R., et al. (2016) · Nature · doi:10.1038/nature18952 · Cited by 505
Self-citationDejnirattisai, W., Wongwiwat, W., Supasa, S., Zhang, X., Dai, X., Rouvinski, A., Jumnainsong, A., Edwards, C., Quyen, N. T. H., Duangchinda, T., et al. (2015) · Nature Immunology · doi:10.1038/ni.3058 · Cited by 500
Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys
Abbink, P., Larocca, R. A., De La Barrera, R. A., Bricault, C. A., Moseley, E. T., Boyd, M., Kirilova, M., Li, Z., Ng’ang’a, D., Nanayakkara, O., et al. (2016) · Science · doi:10.1126/science.aah6157 · Cited by 500
Self-citationDavis, B. S., Chang, G.-J. J., Cropp, B., Roehrig, J. T., Martin, D. A., Mitchell, C. J., Bowen, R., & Bunning, M. L. (2001) · Journal of Virology · doi:10.1128/jvi.75.9.4040-4047.2001 · Cited by 447
Assessing the global threat from Zika virus
Lessler, J., Chaisson, L. H., Kucirka, L. M., Bi, Q., Grantz, K., Salje, H., Carcelen, A. C., Ott, C. T., Sheffield, J. S., Ferguson, N. M., et al. (2016) · Science · doi:10.1126/science.aaf8160 · Cited by 399
Structural Basis of Zika Virus-Specific Antibody Protection
Zhao, H., Fernandez, E., Dowd, K. A., Speer, S. D., Platt, D. J., Gorman, M. J., Govero, J., Nelson, C. A., Pierson, T. C., Diamond, M. S., et al. (2016) · Cell · doi:10.1016/j.cell.2016.07.020 · Cited by 375
Self-citationRecognition determinants of broadly neutralizing human antibodies against dengue viruses
Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.-C., Kikuti, C. M., Navarro Sanchez, M. E., Dejnirattisai, W., Wongwiwat, W., Haouz, A., et al. (2015) · Nature · doi:10.1038/nature14130 · Cited by 357
West Nile Virus Discriminates between DC-SIGN and DC-SIGNR for Cellular Attachment and Infection
Davis, C. W., Nguyen, H.-Y., Hanna, S. L., Sánchez, M. D., Doms, R. W., & Pierson, T. C. (2006) · Journal of Virology · doi:10.1128/jvi.80.3.1290-1301.2006 · Cited by 354
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Self-citationModified mRNA vaccines protect against zika virus infection
Richner, J. M., Himansu, S., Dowd, K. A., Butler, S. L., Salazar, V., Fox, J. M., Julander, J. G., Tang, W. W., Shresta, S., Pierson, T. C., et al. (2017) · Cell · doi:10.1016/j.cell.2017.02.017 · Cited by 909
Self-citationZika virus protection by a single low-dose nucleoside-modified mRNA vaccination
Pardi, N., Hogan, M. J., Pelc, R. S., Muramatsu, H., Andersen, H., DeMaso, C. R., Dowd, K. A., Sutherland, L. L., Scearce, R. M., Parks, R., et al. (2017) · Nature · doi:10.1038/nature21428 · Cited by 884
Self-citationZika Virus Pathogenesis and Tissue Tropism
Miner, J. J., & Diamond, M. S. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.01.004 · Cited by 417
Animal Models of Zika Virus Infection, Pathogenesis, and Immunity
Morrison, T. E., & Diamond, M. S. (2017) · Journal of Virology · doi:10.1128/jvi.00009-17 · Cited by 275
Metadata
- Authors
- Dowd, K. A., Ko, S.-Y., Morabito, K. M., Yang, E. S., Pelc, R. S., DeMaso, C. R., Castilho, L. R., Abbink, P., Boyd, M., Nityanandam, R., Gordon, D. N., Gallagher, J. R., Chen, X., Todd, J.-P., Tsybovsky, Y., Harris, A., Huang, Y.-J. S., Higgs, S., Vanlandingham, D. L., Andersen, H., Lewis, M. G., De La Barrera, R., Eckels, K. H., Jarman, R. G., Nason, M. C., Barouch, D. H., Roederer, M., Kong, W.-P., Mascola, J. R., Pierson, T. C., & Graham, B. S.
- Venue
- Science
- Published
- 2016-10-14
- Volume
- 354
- Issue
- 6309
- Pages
- 237-240
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2521436873
- Cited by
- 396
- References
- 29
- FWCI
- 63.78
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Rapid development of a DNA vaccine for Zika virus. https://app.cochat.ai/papers/10.1126/science.aai9137
- The paper
- Dowd, K. A., Ko, S.-Y., Morabito, K. M., Yang, E. S., Pelc, R. S., DeMaso, C. R., Castilho, L. R., Abbink, P., Boyd, M., Nityanandam, R., Gordon, D. N., Gallagher, J. R., Chen, X., Todd, J.-P., Tsybovsky, Y., Harris, A., Huang, Y.-J. S., Higgs, S., Vanlandingham, D. L., . . . Graham, B. S. (2016). Rapid development of a DNA vaccine for Zika virus. Science. https://doi.org/10.1126/science.aai9137
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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