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Cited by 345

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LRRK2 kinase in Parkinson's disease

Alessi, Dario R., Sammler, Esther·2018·Science
DOI 10.1126/science.aar5683
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Abstract

Defects in vesicular trafficking and immune responses are found in Parkinson's disease

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Crossref · 10.1126/science.aar5683

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  • Mutations in the LRRK2 gene are a common cause of familial Parkinson's disease and are also observed in sporadic Parkinson's disease patients.

    “Mutations in the LRRK2 gene are a common cause of familial Parkinson’s disease (PD) and are also observed in sporadic PD patients, indicating a key role for LRRK2 across the entire disease spectrum [1,2,3].”

    From Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations (2020) · cites this paper as [1]

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Research works printed but not linked: 15

  1. 10.3233/JPD-130192 · DOI
  2. 10.1002/mds.27059 · DOI
  3. 10.1016/B978-0-444-63233-3.00014-2 · DOI
  4. 10.15252/embj.201798099 · DOI · Paper page
  5. 10.1093/hmg/ddx410 · DOI · Paper page
  6. 10.1186/s13024-016-0140-1 · DOI
  7. 10.7554/eLife.12813 · DOI · Paper page
  8. 10.7554/eLife.31012 · DOI · Paper page
  9. 10.15252/embj.201591593 · DOI
  10. 10.1126/science.1129462 · DOI
  11. 10.1007/978-3-319-49969-7_7 · DOI
  12. 10.1038/548534a · DOI
  13. 10.1084/jem.20170014 · DOI
  14. 10.1371/journal.pone.0080705 · DOI
  15. 10.1126/scitranslmed.aaa3634 · DOI

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Metadata

Authors
Alessi, D. R., & Sammler, E.
Affiliations
Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2018-04-06
Volume
360
Issue
6384
Pages
36-37
ISSN
  • 0036-8075
  • 1095-9203
DOI
10.1126/science.aar5683
Cited by
345
References
0
Language
en
Licence
www.sciencemag.org/about/science-licenses-journal-article-reuse (vor)

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