An ingestible bacterial-electronic system to monitor gastrointestinal health

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

Kearse, M., Moir, R., Wilson, A., Stones-Havas, S., Cheung, M., Sturrock, S., Buxton, S., Cooper, A., Markowitz, S., Duran, C., et al. (2012) · Bioinform. · doi:10.1093/bioinformatics/bts199 · Cited by 19,197

Enzymatic assembly of DNA molecules up to several hundred kilobases

Gibson, D. G., Young, L., Chuang, R.-Y., Venter, J. C., Hutchison, C. A., & Smith, H. O. (2009) · Nature Methods · doi:10.1038/nmeth.1318 · Cited by 10,088

Wireless capsule endoscopy

Iddan, G., Meron, G., Glukhovsky, A., & Swain, P. (2000) · Nature · doi:10.1038/35013140 · Cited by 3,066

Automated design of synthetic ribosome binding sites to control protein expression

Salis, H. M., Mirsky, E. A., & Voigt, C. A. (2009) · Nature Biotechnology · doi:10.1038/nbt.1568 · Cited by 1,844

One-step preparation of competent Escherichia coli: transformation and storage of bacterial cells in the same solution.

Chung, C. T., Niemelä, S., & Miller, R. H. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.7.2172 · Cited by 1,602

Peptic ulcer disease

Malfertheiner, P., Chan, F. K. L., & McColl, K. E. L. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60938-7 · Cited by 1,558

Peptic ulcer disease

Lanas, Á., & Chan, F. K. L. (2017) · The Lancet · doi:10.1016/s0140-6736(16)32404-7 · Cited by 989

Principles of genetic circuit design

Brophy, J. A. N., & Voigt, C. A. (2014) · Nature Methods · doi:10.1038/nmeth.2926 · Cited by 965

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

Pickard, J. M., Maurice, C. F., Kinnebrew, M. A., Abt, M. C., Schenten, D., Golovkina, T. V., Bogatyrev, S. R., Ismagilov, R. F., Pamer, E. G., Turnbaugh, P. J., et al. (2014) · Nature · doi:10.1038/nature13823 · Cited by 550

Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application

Schuster, M., Sexton, D. J., Diggle, S. P., & Greenberg, E. P. (2013) · Annual Review of Microbiology · doi:10.1146/annurev-micro-092412-155635 · Cited by 549

Synthetic biology as driver for the biologization of materials sciences

Morales, O. B., Gueye, M., Lacombe, L., Nowak, C., Schmachtenberg, R., Hörner, M., Jerez‐Longres, C., Mohsenin, H., Wagner, H. J., & Weber, W. (2021) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100115 · Cited by 74

Engineered Bacteria-Based Living Materials for Biotherapeutic Applications

Omer, R., Mohsin, M. Z., Mohsin, A., Mushtaq, B. S., Huang, X., Guo, M., Zhuang, Y., & Huang, J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.870675 · Cited by 71

Delivering living medicines with biomaterials

Harimoto, T., Jung, W., & Mooney, D. J. (2025) · Nature Reviews Materials · doi:10.1038/s41578-024-00766-y · Cited by 79

Advances in Materials and Structures for Ingestible Electromechanical Medical Devices

Bettinger, C. J. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201806470 · Cited by 71

A Quantitative Bacteria Monitoring and Killing Platform Based on Electron Transfer from Bacteria to a Semiconductor

Wang, G., Tang, K., Meng, Z., Liu, P., Mo, S., Mehrjou, B., Wang, H., Liu, X., Wu, Z., & Chu, P. K.-H. (2020) · Advanced Materials · doi:10.1002/adma.202003616 · Cited by 70

Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond

English, M. A., Gayet, R. V., & Collins, J. J. (2021) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-013118-111914 · Cited by 71

Smartphone-Based Biosensor Devices for Healthcare: Technologies, Trends, and Adoption by End-Users

Madrid, R. E., Ramallo, F. A., Barraza, D. E., & Chaile, R. E. (2022) · Bioengineering · doi:10.3390/bioengineering9030101 · Cited by 73

Microbiome engineering: engineered live biotherapeutic products for treating human disease

Rutter, J. W., Dekker, L., Owen, K. A., & Barnes, C. P. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1000873 · Cited by 74

Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation

Ramadi, K. B., McRae, J. C., Selsing, G., Su, A., Fernandes, R., Hickling, M., Rios, B., Babaee, S., Min, S., Gwynne, D., et al. (2023) · Science Robotics · doi:10.1126/scirobotics.ade9676 · Cited by 69

From Microbial Fuel Cells to Biobatteries: Moving toward On‐Demand Micropower Generation for Small‐Scale Single‐Use Applications

Gao, Y., Mohammadifar, M., & Choi, S. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201900079 · Cited by 67

Survey of Transfer Learning Approaches in the Machine Learning of Digital Health Sensing Data

Chato, L., & Regentova, E. E. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13121703 · Cited by 74

Implantable application of polymer‐based biosensors

Mei, X., Ye, D., Zhang, F., & Di, C. (2021) · Journal of Polymer Science · doi:10.1002/pol.20210543 · Cited by 64

Living electronics: A catalogue of engineered living electronic components

Atkinson, J. T., Chavez, M. S., Niman, C. M., & El‐Naggar, M. Y. (2022) · Microbial Biotechnology · doi:10.1111/1751-7915.14171 · Cited by 64

Review article: Current status and future directions of ingestible electronic devices in gastroenterology

Thwaites, P. A., Yao, C. K., Halmos, E. P., Muir, J. G., Burgell, R., Berean, K. J., Kalantar‐Zadeh, K., & Gibson, P. R. (2024) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17844 · Cited by 71

Genetically Engineered Microorganisms and Their Impact on Human Health

Mahdizade Ari, M., Dadgar, L., Elahi, Z., Ghanavati, R., & Taheri, B. (2024) · International Journal of Clinical Practice · doi:10.1155/2024/6638269 · Cited by 67

Biosensing in Smart Engineered Probiotics

Rottinghaus, A. G., Amrofell, M. B., & Moon, T. S. (2019) · Biotechnology Journal · doi:10.1002/biot.201900319 · Cited by 63

Living fabrication of functional semi-interpenetrating polymeric materials

Dai, Z., Yang, X., Wu, F., Wang, L., Xiang, K., Li, P., Lv, Q., Tang, J., Dohlman, A. B., Dai, L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23812-7 · Cited by 61

Genetic Engineering of Resident Bacteria in the Gut Microbiome

Arnold, J. H., Glazier, J., & Mimee, M. (2023) · Journal of Bacteriology · doi:10.1128/jb.00127-23 · Cited by 64

Gastrointestinal diagnosis using non-white light imaging capsule endoscopy

Cummins, G., Cox, B. F., Ciuti, G., Anbarasan, T., Desmulliez, M. P. Y., Cochran, S., Steele, R. J., Plevris, J. N., & Koulaouzidis, A. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0140-z · Cited by 62

Microbes as Biosensors

Inda, M. E., & Lu, T. K. (2020) · Annual Review of Microbiology · doi:10.1146/annurev-micro-022620-081059 · Cited by 62

Synthetic Biology Approaches in the Development of Engineered Therapeutic Microbes

Kang, M., Choe, D., Kim, K., Cho, B., & Cho, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228744 · Cited by 61

A Survey for Possible Technologies of Micro/Nanomachines Used for Molecular Communication Within 6G Application Scenarios

Kong, L., Huang, L., Lin, L., Zheng, Z., Li, Y., Wang, Q., & Liu, G. (2023) · IEEE Internet of Things Journal · doi:10.1109/jiot.2023.3255412 · Cited by 61

Ethical and legal issues of ingestible electronic sensors

Gerke, S., Minssen, T., Yu, H., & Cohen, I. G. (2019) · Nature Electronics · doi:10.1038/s41928-019-0290-6 · Cited by 56

Recent Advances in Organ Specific Wireless Bioelectronic Devices: Perspective on Biotelemetry and Power Transfer Using Antenna Systems

Khan, A. N., Cha, Y., Giddens, H., & Hao, Y. (2022) · Engineering · doi:10.1016/j.eng.2021.10.019 · Cited by 57

Organic small molecule semiconductor materials for OFET-based biosensors

Tao, J., Sun, W., & Lu, L. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114667 · Cited by 56

Living electrochemical biosensing: Engineered electroactive bacteria for biosensor development and the emerging trends

Zhu, J., Wang, B., Zhang, Y., Wei, T., & Gao, T. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115480 · Cited by 56

Continuous biochemical profiling of the gastrointestinal tract using an integrated smart capsule

Min, J., Ahn, H., Lukas, H., Ma, X., Bhansali, R., Sunwoo, S., Wang, C., Xu, Y., Yao, D. R., Kim, G., et al. (2025) · Nature Electronics · doi:10.1038/s41928-025-01407-0 · Cited by 59

Integrating bioelectronics with cell-based synthetic biology

Rivnay, J., Raman, R., Robinson, J. T., Schreib, C. C., Cohen‐Karni, T., Galloway, K. E., & Omid Veiseh, A. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-024-00262-6 · Cited by 61

Injectable fiber batteries for all-region power supply in vivo

Zhao, Y., Mei, T., Ye, L., Li, Y., Wang, L., Zhang, Y., Chen, P., Sun, X., Wang, C., & Peng, H. (2020) · Journal of Materials Chemistry A · doi:10.1039/d0ta10357h · Cited by 52

4D printing for biomedical applications

Mandal, A., & Chatterjee, K. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb00006d · Cited by 58

Recent advances in bacteria‐based platforms for inflammatory bowel diseases treatment

Lu, J., Shen, X., Li, H., & Du, J. (2024) · Exploration · doi:10.1002/exp.20230142 · Cited by 57

Microbial bioelectronic sensors for environmental monitoring

Li, S., Zuo, X., Carpenter, M. D., Verduzco, R., & Ajo-Franklin, C. M. (2024) · Nature Reviews Bioengineering · doi:10.1038/s44222-024-00233-x · Cited by 57

Multiplexed detection and differentiation of bacterial enzymes and bacteria by color-encoded sensor hydrogels

Jia, Z., Müller, M., Gall, T. L., Riool, M., Müller, M., Zaat, S. A. J., Montier, T., & Schönherr, H. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.04.022 · Cited by 53

Ingestible devices for studying the gastrointestinal physiology and their application in oral biopharmaceutics.

Weitschies, W., Müller, L., Grimm, M., & Koziolek, M. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113853 · Cited by 40

Engineered live bacteria as disease detection and diagnosis tools

Tanniche, I., & Behkam, B. (2023) · Journal of Biological Engineering · doi:10.1186/s13036-023-00379-z · Cited by 57

Engineered living materials (ELMs) design: From function allocation to dynamic behavior modulation

Wang, Y., Liu, Y., Li, J., Chen, Y., Liu, S., & Zhong, C. (2022) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2022.102188 · Cited by 51

Moving toward smart biomedical sensing

Naghdi, T., Ardalan, S., Adib, Z. A., Sharifi, A. R., & Golmohammadi, H. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.115009 · Cited by 52

Battery-free, wireless, and electricity-driven soft swimmer for water quality and virus monitoring

Li, D., Zhou, J., Zhao, Z., Huang, X., Li, H., Qu, Q., Zhou, C., Yao, K., Liu, Y., Wu, M., et al. (2024) · Science Advances · doi:10.1126/sciadv.adk6301 · Cited by 51

Engineered bacteria to report gut function: technologies and implementation

Tanna, T., Ramachanderan, R., & Platt, R. J. (2020) · Current Opinion in Microbiology · doi:10.1016/j.mib.2020.07.014 · Cited by 50

Intestinal Engineered Probiotics as Living Therapeutics: Chassis Selection, Colonization Enhancement, Gene Circuit Design, and Biocontainment

Huang, Y., Xiaojun, L., Yu, S., Chen, R., & Chen, W.-Z. (2022) · ACS Synthetic Biology · doi:10.1021/acssynbio.2c00314 · Cited by 53

Hydrogel-Embedded Quantum Dot–Transcription Factor Sensors for Quantitative Progesterone Detection

Chen, M., Grazon, C., Sensharma, P., Nguyen, T. T., Feng, Y., Chern, M., Baer, R. C., Varongchayakul, N., Cook, K., Lecommandoux, S., et al. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c13489 · Cited by 52

Nanofiber-based biodegradable millirobot with controllable anchoring and adaptive stepwise release functions

Tan, R., Yang, X., Lu, H., Yang, L., Zhang, T., Miao, J., Feng, Y., & Shen, Y. (2022) · Matter · doi:10.1016/j.matt.2022.01.023 · Cited by 50

Electroceuticals in the Gastrointestinal Tract

Ramadi, K. B., Srinivasan, S. S., & Traverso, G. (2020) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2020.09.014 · Cited by 52

Hydrogel microcapsules containing engineered bacteria for sustained production and release of protein drugs

Han, C., Zhang, X., Pang, G., Zhang, Y., Pan, H., Li, L., Cui, M., Liu, B., Kang, R., Xue, X., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121619 · Cited by 49

Wearable biomolecular sensing nanotechnologies in chronic disease management

Tu, J., Flynn, C. D., Yeom, J., Wu, Z., Kelley, S. O., & Gao, W. F. (2025) · Nature Nanotechnology · doi:10.1038/s41565-025-02010-2 · Cited by 61

Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface

Naydich, A. D., Nangle, S. N., Bues, J., Trivedi, D., Nissar, N., Inniss, M. C., Niederhuber, M. J., Way, J. C., Silver, P. A., & Riglar, D. T. (2019) · mSystems · doi:10.1128/msystems.00125-19 · Cited by 48

A Review of Digital Health and Biotelemetry: Modern Approaches towards Personalized Medicine and Remote Health Assessment

Busnatu, Ș., Niculescu, A.-G., Bolocan, A., Andronic, O., Stoian, A. P., Scafa‐Udriște, A., Stănescu, A. M. A., Păduraru, D. N., Nicolescu, M. I., Grumezescu, A. M., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12101656 · Cited by 50

Shining light on biosensors: Chemiluminescence and bioluminescence in enabling technologies

Roda, B., Deo, S. K., O’Connor, G., Moraskie, M., Giordani, S., Marassi, V., Roda, A., & Daunert, S. (2024) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2024.117975 · Cited by 48

Beyond the Green Fluorescent Protein: Biomolecular Reporters for Anaerobic and Deep-Tissue Imaging

Ozbakir, H. F., Anderson, N. T., Fan, K., & Mukherjee, A. (2019) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.9b00688 · Cited by 49

A red light-controlled probiotic bio-system for in-situ gut-brain axis regulation

Zhang, X., Pang, G., Sun, T., Liu, X., Pan, H., Zhang, Y., Liu, J., Chang, J. K., Wang, H., & Liu, D. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122005 · Cited by 47

Rational design of functional amyloid fibrillar assemblies

Wang, X., Zhang, S., Zhang, J., Wang, Y., Jiang, X., Tao, Y., Li, D., Zhong, C., & Liu, C. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00756h · Cited by 48

Ingestible devices for long-term gastrointestinal residency: a review

Mau, M. M., Sarker, S., & Terry, B. S. (2021) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ac1731 · Cited by 44

A CMOS Multi-Modal Electrochemical and Impedance Cellular Sensing Array for Massively Paralleled Exoelectrogen Screening

Kumashi, S., Jung, D., Park, J.-S., Tejedor‐Sanz, S., Grijalva, S. I., Wang, A. Y., Li, S., Cho, H. C., Ajo-Franklin, C. M., & Wang, H. (2021) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2021.3068710 · Cited by 45

Accounting for the health risk of probiotics

Liu, X., Zhao, H., & Wong, A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27908 · Cited by 44

Video Capsule Endoscopy and Ingestible Electronics: Emerging Trends in Sensors, Circuits, Materials, Telemetry, Optics, and Rapid Reading Software

Miley, D., Machado, L. B., Condo, C., Jergens, A. E., Yoon, K. J., & Pandey, S. (2021) · Advanced Devices & Instrumentation · doi:10.34133/2021/9854040 · Cited by 47

A Novel Enterococcus faecalis Heme Transport Regulator (FhtR) Senses Host Heme To Control Its Intracellular Homeostasis

Saillant, V., Lipuma, D., Ostyn, E., Joubert, L., Boussac, A., Guerin, H., Brandelet, G., Arnoux, P., & Lechardeur, D. (2021) · mBio · doi:10.1128/mbio.03392-20 · Cited by 43

Systems and synthetic biology-driven engineering of live bacterial therapeutics

Kim, K., Kang, M., & Cho, B. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1267378 · Cited by 46

Modular Combination of Proteolysis-Responsive Transcription and Spherical Nucleic Acids for Smartphone-Based Colorimetric Detection of Protease Biomarkers

Liu, F., Chen, R., Song, W., Li, L., Lei, C., & Nie, Z. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.0c04894 · Cited by 42

Future advances of artificial biosensor technology in biomedical applications

Gaba, S., Chauhan, N., Chandra, R., & Jain, U. (2024) · Talanta Open · doi:10.1016/j.talo.2024.100301 · Cited by 42

Recent progress in the imaging detection of enzyme activities in vivo

Yang, C., Wang, Q., & Ding, W. (2019) · RSC Advances · doi:10.1039/c9ra04508b · Cited by 43

RFID Sensors in Medical Applications

Healey, A. J., Fathi, P., & Karmakar, N. C. (2020) · IEEE Journal of Radio Frequency Identification · doi:10.1109/jrfid.2020.2997708 · Cited by 41

A Microstirring Pill Enhances Bioavailability of Orally Administered Drugs

Mundaca‐Uribe, R., Karshalev, E., de Ávila, B. E., Wei, X., Nguyen, B., Litvan, I., Fang, R. H., Zhang, L., & Wang, J. (2021) · Advanced Science · doi:10.1002/advs.202100389 · Cited by 40

A wireless, ingestible pH sensing capsule system based on iridium oxide for monitoring gastrointestinal health

Cheng, C., Wu, Y., Li, X., An, Z., Lu, Y., Zhang, F., Su, B., & Liu, Q. (2021) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2021.130781 · Cited by 42

Flexible Microinterventional Sensors for Advanced Biosignal Monitoring

Liu, Y., Fan, P., Pan, Y., & Ping, J. F. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.5c00115 · Cited by 41

Monitoring of Drug Release via Intra Body Communication with an Edible Pill

Lamanna, L., Cataldi, P., Friuli, M., Demitri, C., & Caironi, M. (2022) · Advanced Materials Technologies · doi:10.1002/admt.202200731 · Cited by 40

Konjac glucomannan-based hydrogels with health-promoting effects for potential edible electronics applications: A mini-review

Waresindo, W. X., Priyanto, A., Sihombing, Y. A., Hapidin, D. A., Edikresnha, D., Aimon, A. H., Suciati, T. A., & Khairurrijal, K. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125888 · Cited by 39

Interfacing gene circuits with microelectronics through engineered population dynamics

Din, M. O., Martín, A., Razinkov, I., Csicsery, N., & Hasty, J. (2020) · Science Advances · doi:10.1126/sciadv.aaz8344 · Cited by 39

An engineered protein-phosphorylation toggle network with implications for endogenous network discovery

Mishra, D., Bepler, T., Teague, B. P., Berger, B., Broach, J. R., & Weiss, R. (2021) · Science · doi:10.1126/science.aav0780 · Cited by 40

Macroencapsulated bacteria for in vivo sensing and therapeutics

Lyu, Y., Huang, H., Su, Y., Ying, B., Liu, W.-C., Dong, K., Du, N., Langer, R., Gu, Z., & Nan, K. (2024) · Matter · doi:10.1016/j.matt.2024.01.031 · Cited by 38

Engineered Bacteria for Disease Diagnosis and Treatment Using Synthetic Biology

Jin, K., Huang, Y. B., Che, H., & Wu, Y. (2025) · Microbial Biotechnology · doi:10.1111/1751-7915.70080 · Cited by 53

Flexible and Stretchable Self‐Powered Multi‐Sensors Based on the N‐Type Thermoelectric Response of Polyurethane/Nax(Ni‐ett)n Composites

Wan, K., Taroni, P. J., Liu, Z., Liu, Y., Tu, Y., Santagiuliana, G., Hsia, I., Zhang, H., Fenwick, O., Krause, S., et al. (2019) · Advanced Electronic Materials · doi:10.1002/aelm.201900582 · Cited by 38

Threat Modeling and Risk Analysis for Miniaturized Wireless Biomedical Devices

Vakhter, V., Soysal, B., Schaumont, P. R., & Güler, Ü. (2022) · IEEE Internet of Things Journal · doi:10.1109/jiot.2022.3144130 · Cited by 49

Rechargeable Micro‐Batteries for Wearable and Implantable Applications

Li, P., Liao, M., Li, J., Ye, L., Cheng, X., Wang, B., & Peng, H. (2022) · Small Structures · doi:10.1002/sstr.202200058 · Cited by 39

Programming living sensors for environment, health and biomanufacturing

Wan, X., Saltepe, B., Yu, L., & Wang, B. (2021) · Microbial Biotechnology · doi:10.1111/1751-7915.13820 · Cited by 36

A Biobattery Capsule for Ingestible Electronics in the Small Intestine: Biopower Production from Intestinal Fluids Activated Germination of Exoelectrogenic Bacterial Endospores

Rezaie, M., Rafiee, Z., & Choi, S. (2022) · Advanced Energy Materials · doi:10.1002/aenm.202202581 · Cited by 36

Living Synthelectronics: A New Era for Bioelectronics Powered by Synthetic Biology

Sun, J., Yang, R., Li, Q., Zhu, R., Jiang, Y., Zang, L., Zhang, Z., Tong, W., Zhao, H., Li, T., et al. (2024) · Advanced Materials · doi:10.1002/adma.202400110 · Cited by 37

Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models

Gao, T., Niu, L., Wu, X., Dai, D., Zhou, Y., Liu, M., Wu, K., Yu, Y., Guan, N., & Ye, H. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101513 · Cited by 39

Studying the Exposome to Understand the Environmental Determinants of Complex Liver Diseases

Cheung, A., Walker, D. I., Juran, B. D., Miller, G. W., & Lazaridis, K. N. (2019) · Hepatology · doi:10.1002/hep.31028 · Cited by 36

Modular tuning engineering and versatile applications of genetically encoded biosensors

Zhang, J., Pang, Q., Wang, Q., Qi, Q., & Wang, Q. (2021) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2021.1982858 · Cited by 36

A soil-inspired dynamically responsive chemical system for microbial modulation

Lin, Y., Gao, X., Yue, J., Fang, Y., Shi, J., Meng, L., Clayton, C., Zhang, X., Shi, F., Deng, J., et al. (2022) · Nature Chemistry · doi:10.1038/s41557-022-01064-2 · Cited by 37

Phase Separation of DNA‐Encoded Artificial Cells Boosts Signal Amplification for Biosensing

Li, J., Cai, Y., Zhang, L., Li, C., Xie, S., Fu, T., Zhang, Z., Li, L., Qi, L., Lyu, Y., et al. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202306691 · Cited by 35

Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases

Gelsinger, D. R., Ronda, C., Ma, J., Kar, O. B., Edwards, M., Huang, Y., Mavros, C. F., Sun, Y., Perdue, T., Vo, P. L. H., et al. (2025) · Science · doi:10.1126/science.adx7604 · Cited by 37

Engineering microbial diagnostics and therapeutics with smart control

Amrofell, M. B., Rottinghaus, A. G., & Moon, T. S. (2020) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2020.05.006 · Cited by 33

From Nano-Communications to Body Area Networks: A Perspective on Truly Personal Communications

Kułakowski, P., Turbić, K., & Correia, L. M. (2020) · IEEE Access · doi:10.1109/access.2020.3015825 · Cited by 35

Cell-based biosensors for immunology, inflammation, and allergy

Inda, M. E., Mimee, M., & Lu, T. K. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.07.024 · Cited by 35

Gelatin‐Based Ingestible Impedance Sensor to Evaluate Gastrointestinal Epithelial Barriers

Balakrishnan, G., Bhat, A., Naik, D. A., Kim, J. S., Marukyan, S., Gido, L., Ritter, M., Khair, A. S., & Bettinger, C. J. (2023) · Advanced Materials · doi:10.1002/adma.202211581 · Cited by 34

Biosensors for point-of-care testing and personalized monitoring of gastrointestinal microbiota

Ngashangva, L., & Chattopadhyay, S. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1114707 · Cited by 34

Synthetic bacterial therapies for intestinal diseases based on quorum-sensing circuits

Dang, Z., Gao, M., Wang, L., Wu, J., Guo, Y., Zhu, Z., Huang, H., & Kang, G. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108142 · Cited by 36

Multifunctional bioelectronics for brain–body circuits

Sahasrabudhe, A., Cea, C., & Anikeeva, P. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00289-3 · Cited by 34

A Whole-Cell Bacterial Biosensor for Blood Markers Detection in Urine

Barger, N., Oren, I., Li, X., Habib, M., & Daniel, R. (2021) · ACS Synthetic Biology · doi:10.1021/acssynbio.0c00640 · Cited by 33

In Vivo Wireless Sensors for Gut Microbiome Redox Monitoring

Baltsavias, S., Treuren, W. V., Weber, M. J., Charthad, J., Baker, S. W., Sonnenburg, J. L., & Arbabian, A. (2019) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2019.2948575 · Cited by 32

Living plastics from plasticizer-assisted thermal molding of silk protein

Wang, Y., Wu, J., Hartzell, E. J., Hu, W., Mahle, R., Li, X., Chen, Y., Sahoo, J. K., Chan, C., Longo, B. N., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55097-x · Cited by 31

Ingestible optoelectronic capsules enable bidirectional communication with engineered microbes for controllable therapeutic interventions

Zhang, X., Feng, Z., Li, H., Yang, H., Li, L., Zhang, C., Dai, P., Wang, H., Xue, H., Wang, Y., et al. (2025) · Nature Microbiology · doi:10.1038/s41564-025-02057-w · Cited by 39

Next-generation biosensing for in situ monitoring

Wang, B., Sanli, A., Lai, Z., Fu, J., Adeel, M., Zhu, X., Yu, M., Qu, L., Li, A., Yang, Z., et al. (2026) · Nature Sensors · doi:10.1038/s44460-025-00016-w · Cited by 36

Engineering E. coli for Magnetic Control and the Spatial Localization of Functions

Aubry, M., Wang, W., Guyodo, Y., Delacou, E., Guigner, J., Espéli, O., Lebreton, A., Guyot, F., & Gueroui, Z. (2020) · ACS Synthetic Biology · doi:10.1021/acssynbio.0c00286 · Cited by 31

Engineering the Microbiome to Prevent Adverse Events: Challenges and Opportunities

Khan, S. M., Hauptman, R., & Kelly, L. (2020) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-031620-031509 · Cited by 30

Engineering E. coli strains using antibiotic-resistance-gene-free plasmids

Amrofell, M. B., Rengarajan, S., Vo, S., Tovar, E. S. R., LoBello, L., Dantas, G. A., & Moon, T. S. (2023) · Cell Reports Methods · doi:10.1016/j.crmeth.2023.100669 · Cited by 33

Implantable Batteries for Bioelectronics

Jiao, Y., He, E., Ye, T., Wang, Y., Yin, H., & Zhang, Y. (2025) · Accounts of Materials Research · doi:10.1021/accountsmr.4c00342 · Cited by 30

Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis

Wei, J., Ding, W., Song, K., Zhang, Y., Luo, Q., & Qi, C. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1581971 · Cited by 30

Electronic Drugs: Spatial and Temporal Medical Treatment of Human Diseases

Won, C., Kwon, C., Park, K., Seo, J., & Lee, T. (2021) · Advanced Materials · doi:10.1002/adma.202005930 · Cited by 30

Ingestible biosensors for gastrointestinal diagnosis

Thomas, H. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0042-5 · Cited by 7

In vivo detection of gut bleeding

Stower, H. (2018) · Nature Medicine · doi:10.1038/s41591-018-0289-y · Cited by 2

Reportage from the gut

Jarchum, I. (2018) · Nature Biotechnology · doi:10.1038/nbt.4177 · Cited by 1

Sub-1.4 cm3 capsule for detecting labile inflammatory biomarkers in situ

Inda, M. E., Jiménez, M., Liu, Q., Phan, N. V., Ahn, J., Steiger, C., Wentworth, A. J., Riaz, A., Zirtiloglu, T., Wong, K., et al. (2023) · Nature · doi:10.1038/s41586-023-06369-x · Cited by 149

Using bugs in the gut to detect blood

Mao, S. (2018) · Science · doi:10.1126/science.360.6391.870-e