Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

Walton, Russell T., Christie, Kathleen A., Whittaker, Madelynn N., Kleinstiver, Benjamin P.·2020·Science

Cited by (1,002)

Items 501–600 of 1,002

  1. Advances in CRISPR-based gene editing technology and its application in nucleic acid detection
    LiWen Chen, JIA LI, Jun Chen, Lili Duan, Zheng Hu, Kai Li, Duan‐Fang Liao, NONGYUE HE · 2024 · Biocell
  2. Mismatch prime editing gRNA increased efficiency and reduced indels
    Jidong Fei, Dongdong Zhao, Caiyi Pang, Ju Li, Siwei Li, Wentao Qiao, Juan Tan, Changhao Bi, Xueli Zhang · 2025 · Nature Communications
  3. A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9
    Lan Hu, Jing Han, Hao-Da Wang, Zhou‐Hua Cheng, Chang-Ce Lv, Dong‐Feng Liu, Han‐Qing Yu · 2025 · Nature Communications
  4. Engineering eukaryotic transposon-encoded Fanzor2 system for genome editing in mammals
    Yinghui Wei, Pengfei Gao, Deng Pan, Guoling Li, Yufei Chen, Shangpu Li, Henan Jiang, Yue Yang, Zhuo Liu, Zujiang Liu et al. · 2025 · Nature Chemical Biology
  5. Multiplex base editing of RBSs rewires Bacillus subtilis metabolism for lycopene overproduction
    Yang Liu, Xianhai Cao, Xiaojuan Wang, Ruirui Chen, Boxin Yuan, Shixin Li, Yu Wang, Xiaoping Liao, Xiaomeng Ni, Lixian Wang et al. · 2025 · Metabolic Engineering
  6. A novel base editor SpRY-ABE8eF148A mediates efficient A-to-G base editing with a reduced off-target effect
    Guo Li, Yaxian Cheng, Yeqiu Li, Hongru Ma, Zhongji Pu, Sa Li, Yiqiang Zhao, Xingxu Huang, Yuan Yao · 2022 · Molecular Therapy — Nucleic Acids
  7. Correcting inborn errors of immunity: From viral mediated gene addition to gene editing
    Maria Carmina Castiello, Samuele Ferrari, ANNA MARIA VILLA · 2023 · Seminars in Immunology
  8. Genome editing for plant synthetic metabolic engineering and developmental regulation
    Jiantao Tan, Mengyuan Shen, Nan Chai, Qi Liu, Yao‐Guang Liu, Qinlong Zhu · 2023 · Journal of Plant Physiology
  9. Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock
    Yuguo Yuan, Song-Zi Liu, Muhammad Farhab, Mei-Yun Lv, Ting Zhang, Shao-Xiao Cao · 2024 · Functional & Integrative Genomics
  10. Precision in Action: The Role of Clustered Regularly Interspaced Short Palindromic Repeats/Cas in Gene Therapies
    Amrutha Banda, Olivia Impomeni, Aparana Singh, Abdul Rasheed Baloch, Wenhui Hu, Dabbu Kumar Jaijyan · 2024 · Vaccines
  11. The 4Fs of cotton: genome editing of cotton for fiber, food, feed, and fuel to achieve zero hunger
    Muhammad Sulyman Saleem, Sultan Habibullah Khan, Aftab Ahmad, Iqrar Ahmad Rana, Zunaira Afzal Naveed, Azeem Iqbal Khan · 2024 · Frontiers in Genome Editing
  12. DNA targeting by compact Cas9d and its resurrected ancestor
    Rodrigo Fregoso Ocampo, Jack P. K. Bravo, Tyler L. Dangerfield, Isabel Nocedal, Samatar Ali Jirde, Lisa M. Alexander, Nicole C. Thomas, Anjali Das, Sarah Nielson, Kenneth Allen Johnson et al. · 2025 · Nature Communications
  13. Rewriting CFTR to cure cystic fibrosis
    Giulia Maule, Marjolein M. Ensinck, Mattijs Bulcaen, Marianne Sylvia Carlon · 2021 · Progress in molecular biology and translational science
  14. Modified Gene Editing Systems: Diverse Bioengineering Tools and Crop Improvement
    Guoning Zhu, Hongliang Zhu · 2022 · Frontiers in Plant Science
  15. Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors
    Jianan Li, Jianxiang Lin, Shisheng Huang, Min Li, Wenxia Yu, Yuting Zhao, Junfan Guo, Pumin Zhang, Xingxu Huang, Yunbo Qiao · 2022 · Advanced Science
  16. Engineering CRISPR/Cas-based nanosystems for therapeutics, diagnosis and bioimaging
    Nachuan Song, Shuai Li, Zhaoyue Lv, Xiaohui Ding, Feng Li, Dayong Yang · 2023 · Chinese Chemical Letters
  17. Correction of the pathogenic mutation in TGM1 gene by adenine base editing in mutant embryos
    Lu Dang, Xueliang Zhou, Xiufang Zhong, Wenxia Yu, Shisheng Huang, Hanyan Liu, Yuanyuan Chen, Wuwen Zhang, Lihua Yuan, Lei Li et al. · 2021 · Molecular Therapy
  18. Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment
    Malbranke, Cyril, Rostain, William, Depardieu, Florence, Cocco, Simona, Monasson, Rémi, Bikard, David · 2023 · PLOS Computational Biology
  19. Emerging trends in gene and cell therapy: CRISPR in DNA editing and beyond
    Ruijin Ji, Qiubing Chen, Ying Zhang · 2025 · Cell Reports Medicine
  20. Organ Transplantation: Current Status, Challenges, and Future Prospects
    Xinqiang Li, Ruidong Ding, Jinzhen Cai · 2026 · MedComm
  21. In vivo application of base and prime editing to treat inherited retinal diseases
    Dong Hyun Jo, Sangsu Bae, Seokjoong Kim, Jin‐Soo Kim, Jeong Hun Kim · 2022 · Progress in Retinal and Eye Research
  22. Protocol for gene characterization in Aspergillus niger using 5S rRNA-CRISPR-Cas9-mediated Tet-on inducible promoter exchange
    Xiaomei Zheng, Timothy C. Cairns, Ping Zheng, Vera Meyer, Jibin Sun · 2022 · STAR Protocols
  23. Decoding CRISPR–Cas PAM recognition with UniDesign
    Xiaoqiang Huang, Jun Zhou, Dongshan Yang, Jifeng Zhang, Xiaofeng Xia, Y. Eugene Chen, Jie Xu · 2023 · Briefings in Bioinformatics
  24. The construction of a PAM-less base editing toolbox in Bacillus subtilis and its application in metabolic engineering
    Yan Xia, Lichao Sun, Zeyu Liang, Yingjie Guo, Jing Li, Dan Tang, Yi‐Xin Huo, Shuyuan Guo · 2023 · Chemical Engineering Journal
  25. Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors
    Michael Gapinske, Jackson Winter, Devyani Swami, Lauren Gapinske, Wendy S. Woods, Shraddha Shirguppe, Angelo Miskalis, Anna M. Busza, Dana Joulani, Collin J. Kao et al. · 2023 · Molecular Therapy — Nucleic Acids
  26. Genome and transcriptome engineering by compact and versatile CRISPR-Cas systems
    Guillermo Aquino‐Jarquín · 2023 · Drug Discovery Today
  27. Precise base editing without unintended indels in human cells and mouse primary myoblasts
    Da Eun Yoon, Narae Kim, Soo-Ji Park, Tae Yeong Jeong, Bokkee Eun, Yongcheol Cho, Sooyeon Lim, Hyunji Lee, Je Kyoung Seong, Kyoungmi Kim · 2023 · Experimental & Molecular Medicine
  28. The immune system of prokaryotes: potential applications and implications for gene editing
    SiYang Maggie Liu, Hongling Liu, Xue Wang, Lei Shi · 2024 · Biotechnology Journal
  29. Base Editors-Mediated Gene Therapy in Hematopoietic Stem Cells for Hematologic Diseases
    Chengpeng Zhang, Jinchao Xu, Yikang Wu, Can Xu, Peng Xu · 2024 · Stem Cell Reviews and Reports
  30. Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a
    Lorenzo Olivi, Cleo Bagchus, Victor D. Pool, Ezra T. Bekkering, Konstantin Speckner, Hidde S. Offerhaus, Wen Y. Wu, Martin Depken, Koen J.A. Martens, Raymond H.J. Staals et al. · 2024 · Nucleic Acids Research
  31. CRISPR-Cas Genome Editing in Ex Vivo Human Lungs to Rewire the Translational Path of Genome-Targeting Therapeutics
    Kumi Mesaki, Haruchika Yamamoto, S. Juvet, Jonathan C. Yeung, Zehong Guan, Akhi Akhter, Yan Yao, Cameron Dickie, Henna Mangat, Aizhou Wang et al. · 2024 · Human Gene Therapy
  32. Developing benzylisoquinoline alkaloid-enriched opium poppy via CRISPR-directed genome editing: A review
    Zahra Aghaali, Mohammad Reza Naghavi · 2024 · BMC Plant Biology
  33. Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs
    Hanwen Zhang, Ada McCarroll, Lilia Peyton, Sol Díaz de León‐Guerrero, Siwei Zhang, Prarthana Gowda, David Sirkin, Mahmoud ElAchwah, Alexandra Duhe, Whitney Wood et al. · 2024 · Stem Cell Reports
  34. Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells
    Christi T. Salisbury-Ruf, André Larochelle · 2021 · Journal of Clinical Medicine
  35. Evolution-aided engineering of plant specialized metabolism
    Mohammad Irfan, Benjamin G. Chavez, Paride Rizzo, John C. D’Auria, Gaurav D. Moghe · 2021 · aBIOTECH
  36. Development of Whole Genome‐Scale Base Editing Toolbox to Promote Efficiency of Extracellular Electron Transfer in Shewanella oneidensis MR‐1
    Yaru Chen, Lixia Fang, Xiang Ying, Meijie Cheng, Lin Wang, Panxing Sun, Zhaoyu Zhang, Liang Shi, Yingxiu Cao, Hao Song · 2022 · Advanced Biology
  37. Non-coding RNA: Chief architects of drought-resilient roots
    Zahra Ghorbanzadeh, Rasmieh Hamid, Feba Jacob, Sara Asadi, Ghasem Hosseini Salekdeh, Mohammad Reza Ghaffari · 2022 · Rhizosphere
  38. Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria
    Jian Wang, Yuxi Teng, Xinyu Gong, Jianli Zhang, Yifei Wu, Lei Lou, Michelle Li, Zhong‐Ru Xie, Yajun Yan · 2022 · Metabolic Engineering
  39. Genome editing with natural and engineered CjCas9 orthologs
    Siqi Gao, Yao Wang, Tao Qi, Jingjing Wei, Ziying Hu, Jingtong Liu, Shuna Sun, Huihui Liu, Yongming Wang · 2023 · Molecular Therapy
  40. Functional annotation of variants of the BRCA2 gene via locally haploid human pluripotent stem cells
    Hanqin Li, Rebecca Bartke, Lei Zhao, Yogendra Verma, Anna Horacek, Alma Rechav Ben-Natan, Gabriella Rita Pangilinan, Netravathi Krishnappa, Rasmus Nielsen, Dirk F. Hockemeyer · 2023 · Nature Biomedical Engineering
  41. Precise mutagenesis in zebrafish using cytosine base editors
    Marion Rosello, Malo Serafini, Jean‐Paul Concordet, Filippo Del Bene · 2023 · Nature Protocols
  42. Eukaryotic-driven directed evolution of Cas9 nucleases
    2024
  43. AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing
    Muralikrishna Narra, Anamika Ray, Brittany Polley, Hui Yang, Pankaj Bhowmik · 2025 · Frontiers in Plant Science
  44. Non‐synonymous , synonymous, and non‐coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression
    Kevin Stachelek, Narine Harutyunyan, Susan Lee, Assaf Beck, Jonathan W. Kim, Liya Xu, Jesse L. Berry, Aaron Nagiel, C. Patrick Reynolds, A. Linn Murphree et al. · 2022 · Genes Chromosomes and Cancer
  45. Clinical and Therapeutic Evaluation of the Ten Most Prevalent CRB1 Mutations
    Bruna Lopes da Costa, Masha Kolesnikova, Sarah R. Levi, Thiago Cabral, Stephen H. Tsang, Irene Hussels Maumenee, Peter M. J. Quinn · 2023 · Biomedicines
  46. Structural snapshots of R-loop formation by a type I-C CRISPR Cascade
    Roisin E. O’Brien, Jack P. K. Bravo, Delisa Ramos, Grace N. Hibshman, Jacquelyn T. Wright, David Ward Taylor · 2023 · Molecular Cell
  47. Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophila cells
    Baolong Xia, Raghuvir Viswanatha, Yanhui Hu, Stephanie Elizabeth Mohr, Norbert Perrimon · 2023 · eLife
  48. Design and application of the transformer base editor in mammalian cells and mice
    Wenyan Han, Bao‐Qing Gao, Junjie Zhu, Zongxing He, Jianfeng Li, Li Chun Yang, Jia Chen · 2023 · Nature Protocols
  49. Preclinical Anticipation of On- and Off-Target Resistance Mechanisms to Anti-Cancer Drugs: A Systematic Review
    Paulina J. Dziubańska-Kusibab, Ekaterina Nevedomskaya, Bernard Haendler · 2024 · International Journal of Molecular Sciences
  50. Boosting genome editing in plants with single transcript unit surrogate reporter systems
    Xu Tang, Qiurong Ren, Xiaodan Yan, Rui Zhang, Li Liu, Qinqin Han, Xuelian Zheng, Yiping Qi, Hongyuan Song, Yong Zhang · 2024 · Plant Communications
  51. Analyzing the functional effects of DNA variants with gene editing
    Sarah Cooper, Sofia Obolenski, Andrew J. Waters, Andrew Roger Bassett, Matthew A. Coelho · 2024 · Cell Reports Methods
  52. Advanced Genome Editing Technologies: Potentials and Prospects in Improvement of Sugar crops
    G. Amaresh, Aswini Nunavath, C. Appunu, C. Viswanathan, RAJEEV RANJAN KUMAR, Ranjit Singh Gujjar, R. Manimekalai · 2024 · Sugar Tech
  53. Current Knowledge of Base Editing and Prime Editing
    Olga A. Averina, S. A. Kuznetsova, Oleg A. Permyakov, Сергиев Петр Владимирович · 2024 · Molecular Biology
  54. Gene editing in common cardiovascular diseases.
    Anna-Maria Lauerer, Xurde M. Caravia, Lars S. Maier, Francesco Chemello, S. Lebek · 2024 · Pharmacology and Therapeutics
  55. High-Sensitivity Enzyme-Free Fluorescence Probe Based on CRISPR/Cas13 and the Isothermal Amplification Strategy for Axl Sensing
    Yunsu Ma, Yiping Tan, Jing Li, Qian Xiang, Sunan Liu, Xiaojuan Jin, Simin Shao, Wei Geng, Ling Zhu, Dongzhi Yang · 2024 · Analytical Chemistry
  56. Amelioration of metabolic and behavioral defects through base editing in the PahR408W phenylketonuria mouse model
    Shuming Yin, Liangcai Gao, Xiaoyue Sun, Mei Zhang, Hong-Yi Gao, Xiaoqing Chen, Dan Zhang, Xinyu Ming, Lei Yang, Yaqiang Hu et al. · 2024 · Molecular Therapy
  57. Advancing fish disease research through CRISPR-Cas genome editing: Recent developments and future perspectives
    Huria Marnis, Khairul Syahputra · 2025 · Fish & Shellfish Immunology
  58. Advancements in CRISPR-Cas-based strategies for combating antimicrobial resistance
    Ruiting Zhang, Qi Zhou, Siying Huang, Nan Zhang, Dongchang Sun · 2025 · Microbiological Research
  59. CRISPR-based functional genomics tools in vertebrate models
    Gaurav K. Varshney, Shawn Michael Burgess · 2025 · Experimental & Molecular Medicine
  60. Use of CRISPR/Cas ribonucleoproteins for high throughput gene editing of induced pluripotent stem cells
    Qi Wang, Sueanne Chear, Kristof Wing, David Stellon, Minh Thuan Nguyen Tran, Jana Talbot, Alice Pébay, Alex William Hewitt, Anthony L Cook · 2021 · Methods
  61. Genome Editing Technology and Its Application to Metabolic Engineering in Rice
    Satoru Sukegawa, Seiichi Toki, Hiroaki Saika · 2022 · Rice
  62. Enhancing the quality of staple food crops through CRISPR/Cas-mediated site-directed mutagenesis
    Olawale Samuel Adeyinka, Bushra Tabassum, Koloko Brice Landry, Ifedayo Victor Ogungbe · 2023 · Planta
  63. Integrative dissection of gene regulatory elements at base resolution
    Zeyu Chen, Nauman M. Javed, Molly M. Moore, Jingyi Wu, Gary Sun, Michael E. Vinyard, Alejandro Collins, Luca Pinello, Fadi J. Najm, B Bernstein · 2023 · Cell Genomics
  64. Enhancing prime editor flexibility with coiled-coil heterodimers
    Shuangshuang Mu, Huangyao Chen, Qianru Li, Shixue Gou, Xiaoyi Liu, Junwei Wang, Wei Zheng, Menglong Chen, Qin Jin, Liangxue Lai et al. · 2024 · Genome biology
  65. Current trends in gene therapy to treat inherited disorders of the brain
    Żaneta Matuszek, Brandon L. Brown, Carolyn M. Yrigollen, Megan S. Keiser, Beverly L. Davidson · 2025 · Molecular Therapy
  66. CRISPR/Cas9: an overview of recent developments and applications in cancer research
    Shamjetsabam Nandibala Devi, Rashmi Rana, Priyanka Malik, Nirmal Kumar Ganguly · 2024 · International Journal of Surgery
  67. Why Does the E1219V Mutation Expand T-Rich PAM Recognition in Cas9 from Streptococcus pyogenes?
    Shreya Bhattacharya, Priyadarshi Satpati · 2024 · Journal of Chemical Information and Modeling
  68. Diverse nucleotide substitutions in rice base editing mediated by novel TadA variants
    Man Yu, Yongjie Kuang, Chenyang Wang, Xuemei Wu, Shaofang Li, Dawei Zhang, Wenxian Sun, Xueping Zhou, Ren Bin, Huanbin Zhou · 2024 · Plant Communications
  69. Gene editing therapy for cardiovascular diseases
    Xinyu Wu, Jie Yang, Jiayao Zhang, Yuning Song · 2024 · MedComm
  70. Comparison of CRISPR/Cas9 and Cas12a for gene editing in Chlamydomonas reinhardtii
    Áron Ferenczi, Matthew Fellbaum, Yen Peng Chew, Catherine Anne Kidner, Attila Molnár · 2024 · Algal Research
  71. Genetic advancements in breast cancer treatment: a review
    Marzieh Shokoohi, Sadaf Sedaghatshoar, Homaira Arian, Milad Mokarami, Fatemeh Habibi, Fatemeh Bamarinejad · 2025 · Discover Oncology
  72. Make-or-break prime editing for genome engineering in Streptococcus pneumoniae
    Rengifo-Gonzalez Monica, Maria-Vittoria Mazzuoli, Axel B. Janssen, Anne-Stéphanie Rueff, Jessica Burnier, Xue Liu, Jan‐Willem Veening · 2025 · Nature Communications
  73. PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
    Shao Wei Hu, Sohyang Jeong, Luoying Jiang, Hansol Koo, Zijing Wang, Won Hoon Choi, Biyun Zhu, Heeyoung Seok, Yi Zhou, Min Gu Kim et al. · 2025 · Nature Communications
  74. Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice
    Christiano R. R. Alves, Sabyasachi Das, Vijai Krishnan, Leillani L. Ha, Lauren R. Fox, Hannah E. Stutzman, Claire E. Shamber, Pazhanichamy Kalailingam, Siobhan McCarthy, Christian Lacks Lino Cardenas et al. · 2025 · Nature Biomedical Engineering
  75. enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9
    Jasper Edgar Neggers, Maarten Jacquemyn, Tim Dierckx, Benjamin P. Kleinstiver, Hendrik Jan Thibaut, Dirk Daelemans · 2020 · Molecular Therapy
  76. Bridging photosynthesis and crop yield formation with a mechanistic model of whole-plant carbon–nitrogen interaction
    Tiangen Chang, Zhong-Wei Wei, Zai Shi, Yi Xiao, Honglong Zhao, Shuo-Qi Chang, Mingnan Qu, Qingfeng Song, Faming Chen, Fenfen Miao et al. · 2023 · in silico Plants
  77. Small-molecule compounds boost genome-editing efficiency of cytosine base editor
    Tianyuan Zhao, Qing Li, Chenchen Zhou, Xiujuan Lv, Hongyan Liu, Tianxiang Tu, Na Tang, Yanbo Cheng, Xiaoyu Liu, Changbao Liu et al. · 2021 · Nucleic Acids Research
  78. Development and expansion of the CRISPR/Cas9 toolboxes for powerful genome engineering in yeast
    Cai Guang, Zhenquan Lin, Shuobo Shi · 2022 · Enzyme and Microbial Technology
  79. Editing the genome of common cereals (Rice and Wheat): techniques, applications, and industrial aspects
    Niharika Das, Debasmita Ghosh Dhar, Priyanka Dhar · 2022 · Molecular Biology Reports
  80. A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets
    Péter István Kulcsár, András Tálas, Zoltán Ligeti, Eszter Tóth, Zsófia Rakvács, Zsuzsa Bartos, Sarah Laura Krausz, Ágnes Welker, Vanessza Laura Végi, Krisztina Huszár et al. · 2023 · Nature Communications
  81. Engineering CRISPR guide RNAs for programmable RNA sensors
    Yang Liu, Wei Yong Liu, Baojun Wang · 2023 · Biochemical Society Transactions
  82. Context base editing for splice correction of IVSI-110 β-thalassemia
    Basma Naiisseh, Panayiota L. Papasavva, Nikoletta Y. Papaioannou, Marios Tomazou, Lola Koniali, Xenia Felekis, Constantina G. Constantinou, Maria Sitarou, Soteroula Christou, Marina Kleanthous et al. · 2024 · Molecular Therapy — Nucleic Acids
  83. Sensing through Non-Sensing Ocular Ion Channels
    Meha Kabra, Bikash Ranjan Pattnaik · 2020 · International Journal of Molecular Sciences
  84. Nickase fidelity drives EvolvR-mediated diversification in mammalian cells
    Juan E. Hurtado, Adam J. Schieferecke, Shakked O. Halperin, John Guan, Dylan Aidlen, David V. Schaffer, John E. Dueber · 2025 · Nature Communications
  85. Advances in large-scale DNA engineering with the CRISPR system
    Lee Wha Gwon, Isabel Wen Badon, Youngjeon Lee, Ho‐Joong Kim, Seung Hwan Lee · 2025 · Experimental & Molecular Medicine
  86. Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming
    Yanlong Li, X. Zhang, Chan Xia, Ting Wu, Yuyu Gao, Lingen Zeng, Zhuoxuan Wu, Xiongze Dai, Fang Yuan, Feng Liu et al. · 2025 · Horticulture Research
  87. DNA and RNA editing for the therapy of human diseases: current status, challenges, and future prospects
    Rui Zhao, Changli Wang, 李佳楣, Yan Liao, Chenwei Huang, Ting Hu, Haoling Zhang, Wangzheqi Zhang · 2026 · Molecular Biomedicine
  88. Molecular and Computational Strategies to Increase the Efficiency of CRISPR-Based Techniques
    Lucia Mattiello, Mark Rütgers, Maria Fernanda Sua-Rojas, Rafael Tavares, José Sérgio Soares, Kevin Begcy, Marcelo Menossi · 2022 · Frontiers in Plant Science
  89. CRISPR/Cas systems usher in a new era of disease treatment and diagnosis
    Ruiting Li, Qin Wang, Kaiqin She, Fang Lu, Yang Yang · 2022 · Molecular Biomedicine
  90. A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9
    Yuqiang Qian, Di Wang, Wenchao Niu, Ding Zhao, Jinze Li, Zhiquan Liu, Xun Gao, Yang Han, Liangxue Lai, Zhanjun Li · 2023 · BMC Biology
  91. Massively parallel CRISPR-assisted homologous recombination enables saturation editing of full-length endogenous genes in yeast
    Lei Deng, Yi‐Lian Zhou, Zhenkun Cai, Jie Zhu, Zenan Li, Zehua Bao · 2024 · Science Advances
  92. Navigating the CRISPR/Cas Landscape for Enhanced Diagnosis and Treatment of Wilson’s Disease
    Woong Choi, Seongkwang Cha, Kyoungmi Kim · 2024 · Cells
  93. Unleashing the Potential of CRISPR/Cas9 Genome Editing for Yield-Related Traits in Rice
    Archana Thiruppathi, Shubham Rajaram Salunkhe, Shobica Priya Ramasamy, Rakshana Palaniswamy, Veera Ranjani Rajagopalan, Sakthi Ambothi Rathnasamy, A. Senthil, Manonmani Swaminathan, M. Sudha, M. Raveendran · 2024 · Plants
  94. CRISPR/Cas9 and its derivatives to improve crop biotic stress resistance: Current status and prospects
    Rituja Chattopadhyay, Zulikha Firdous, Vinay Kumar Bari · 2024 · Physiological and Molecular Plant Pathology
  95. Prime Editing: Mechanistic Insights and DNA Repair Modulation
    Astrid Mentani, Marcello Maresca, Anna Shiriaeva · 2025 · Cells
  96. Predicting adenine base editing efficiencies in different cellular contexts by deep learning
    Lucas Kissling, Amina Mollaysa, Sharan Janjuha, Nicolas Mathis, Kim Fabiano Marquart, Yanik Weber, Woohyun J Moon, Paulo J.C. Lin, Steven H.Y. Fan, Hiromi Muramatsu et al. · 2025 · Genome biology
  97. Microalgal bioengineering for futuristic applications in synthetic and space biology
    Rahul Mahadev Shelake, M A Khalid, Jae‐Yean Kim · 2025 · Biotechnology Advances
  98. Precise gene editing of pathogenic Lamin A mutations corrects cardiac disease
    Xurde M. Caravia, Brian Hayashi, Hui zi Li, Peiheng Gan, Damir Alzhanov, Wei Hong Tan, Kenian Chen, John McAnally, Lin Xu, Ning Liu et al. · 2025 · Proceedings of the National Academy of Sciences
  99. PAM-less is more
    Lei Tang · 2020 · Nature Methods
  100. CRISPR technology for abiotic stress resistant crop breeding
    Lingling Ma, Zhen Liang · 2021 · Plant Growth Regulation